Neurology
Brain & nervous system clinical trials
Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We’re tracking 12,425 recruiting studies in this area right now.
By phase
- Not applicable9,762
- Phase 2784
- Phase 1574
- Phase 3535
- Phase 4342
- Phase 1/Phase 2305
- Phase 2/Phase 3123
Top conditions
- Stroke845
- Parkinson Disease426
- Multiple Sclerosis343
- Alzheimer Disease341
- Dementia226
- Ischemic Stroke200
- Epilepsy197
- Obstructive Sleep Apnea155
- Spinal Cord Injuries154
- Insomnia153
- Sarcopenia149
- Traumatic Brain Injury149
- Acute Ischemic Stroke139
- Cerebral Palsy131
- Mild Cognitive Impairment129
- Pain Management114
- Migraine112
- Amyotrophic Lateral Sclerosis108
Leading sponsors
- Beijing Tiantan Hospital133
- Riphah International University125
- Assistance Publique - Hôpitaux de Paris112
- Mayo Clinic99
- Xuanwu Hospital, Beijing94
- VA Office of Research and Development93
- Hospices Civils de Lyon79
- Johns Hopkins University70
- National Taiwan University Hospital70
- University of Minnesota64
Where studies are running
- California678
- Massachusetts300
- New York292
- Florida275
- Texas267
- Maryland245
- Arizona213
- Alabama211
- Illinois189
- Pennsylvania178
Recruiting studies12,423 total
- NCT04046237Recruiting
Treating gum disease to study heart artery inflammation after a heart attack
This study tests whether treating severe gum disease in people who recently had a heart attack can reduce inflammation in the artery plaque. It may help researchers understand if gum treatment could benefit heart health after a heart attack.
ParisAges 30–70 - NCT04045665RecruitingPhase 3
Blood thinner vs usual care for new heart rhythm after bypass surgery
This trial tests whether using a blood thinner in people with new, temporary atrial fibrillation after CABG (heart bypass surgery) can reduce harmful outcomes compared with standard treatment. It may help prevent stroke or other complications if your rhythm problem fits the trial’s timing and risk profile.
Little Rock, ArkansasAges 18 years+ - NCT04046523Recruiting
Test non-contact eye videos to measure brain pressure waves
This study uses a special video exam of your eyes to record patterns that may relate to brain pressure changes. It may help researchers find a safer, non-contact way to monitor pressure inside the skull.
Minneapolis, MinnesotaAges 4 years+ - NCT04047992Recruiting
Training seated balance with the Indego leg device
This study tests whether using the Indego device can improve balance and movement for people with spinal cord injury (SCI). You would practice standing or balance tasks with the device if you meet the safety and fit requirements.
The Bronx, New YorkAges 18 years+ - NCT04049331RecruitingPhase 2
Testosterone therapy for cancer survivors with fatigue
This trial tests whether testosterone replacement can help male cancer survivors who have ongoing fatigue and low testosterone levels. It is for men who have completed chemotherapy or radiation and are cancer-free for at least a year.
Boston, MassachusettsAges 18–54 - NCT04050995Recruiting
Testing MuSICCA to measure awareness in children
This study tests a tool called MuSICCA to check awareness in children and teens who are being evaluated for a disorder of consciousness. The results may help clinicians better understand a child’s awareness and guide care decisions.
Atlanta, GeorgiaAges 2–18 - NCT04060030RecruitingPhase 2
Leucovorin for young children with autism language difficulties
This Phase 2 study tests whether leucovorin (a vitamin-related medicine) can improve social communication and language in young children with autism. It also looks at safety and whether the results hold while the child stays on their usual therapies and routines.
Phoenix, ArizonaAges 2.5 years–5 years - NCT04057638Recruiting
Facial and hand transplant study for severe face and hand loss
This trial looks at transplanting donor tissue to rebuild parts of the face and one or both hands/forearms after major damage or loss. It aims to see if this approach can restore function and appearance, while carefully managing safety and side effects like the need for long-term immune-suppressing medicines.
New York, New YorkAges 18–64 - NCT04058457Recruiting
Deep brain stimulation for people with Parkinson’s
This study looks at how deep brain stimulation (DBS) affects breathing in people who have Parkinson’s disease and are planning DBS surgery. You may be able to help researchers learn whether DBS changes breathing and how to manage it safely.
Oxford, OxfordshireAges 18 years+ - NCT04063592Recruiting
Surgery plan for pain or skin problems in a healed leg stump
This study looks at a surgical approach for people who already had an above-knee or below-knee amputation and now have ongoing pain or skin/stump problems that haven’t improved. It aims to improve comfort and how well the stump area heals, assuming you’re healthy enough for surgery under standard anesthesia.
Bethesda, MarylandAges 18–65 - NCT04059276Recruiting
Brain scan study of stroke-related changes
This study uses brain magnetic resonance imaging (MRI) scans to look at changes in the brain after a stroke. It may help researchers better understand what happens in the brain over time and improve future care.
ZurichAges 18–80 - NCT04061135Recruiting
Study brain and movement patterns in Parkinson’s or tremor
This study looks at brain signals, thinking, and movement behaviors in people who have Parkinson’s disease or essential tremor and are being considered for deep brain stimulation (DBS) surgery. It may help researchers better understand how DBS affects the brain and day-to-day function.
Birmingham, AlabamaAges 18 years+ - NCT04062292Recruiting
Study of walking balance in lung disease and healthy adults
This study measures how people with obstructive lung diseases walk and maintain balance, compared with people without lung disease. It may help researchers understand movement and balance problems that can happen with breathing conditions.
AnkaraAges 18–65 - NCT04063540RecruitingPhase 2
Amiloride to prevent migraine aura episodes
This study tests whether amiloride can reduce how often migraine aura happens. It’s a proof-of-concept early study, meaning the main goal is to see if the approach seems to work and is safe for people with frequent aura.
BronAges 18–80 - NCT04064307Recruiting
Register people with myotubular or centronuclear myopathy
This study sets up a patient registry for people diagnosed with myotubular myopathy or centronuclear myopathy. Your information can help researchers better understand these conditions and plan future studies or treatments.
Newcastle upon Tyne, Tyne and WearAges Any age - NCT04066348RecruitingPhase 2
TNF medication trial for blast-related tinnitus
This Phase 2 study tests whether a TNF-α medicine can reduce tinnitus symptoms after blast or loud noise exposure, sometimes with traumatic brain injury. You may be a candidate if your tinnitus is at least moderately severe and stable over time, and if you meet other health and medication rules.
Celebration, FloridaAges 18 years+ - NCT04067167Recruiting
Exercise bands versus muscle stimulation for people with cancer
This trial compares two types of exercise—flexible resistance band training versus a type of muscle stimulation—to see which is safe and helpful during cancer treatment. It may help improve physical function while you’re receiving anti-cancer care.
ErlangenAges 18 years+ - NCT04066465Recruiting
Testing how proton therapy affects thinking in young people
This study looks at how proton radiation therapy may affect thinking, learning, and brain function in children and teens with a primary brain tumor. It uses repeated short brain/learning tests to track possible changes over time.
Dresden, SaxonyAges 8–18 - NCT04071847Recruiting
Study tracking results after Abbott deep brain stimulator surgery
This study follows people who are getting a new Abbott deep brain stimulator (DBS) device or replacing the battery/implantable pulse generator to see how outcomes change over time. It mainly applies to certain DBS targets and diagnoses, and it uses follow-up visits to track results.
Tucson, ArizonaAges Any age - NCT04070937Recruiting
Imaging findings and balance function in bilateral vestibulopathy
This study compares CT/MRI imaging results (radiological lesions) with balance system function tests in people with bilateral vestibulopathy. The goal is to see whether changes seen on scans match how well your inner-ear/balance nerves are working, which could improve understanding and future treatment decisions.
Hasselt, LimburgAges 18–90 - NCT04073290RecruitingPhase 4
Rifaximin and lactulose to prevent confusion after TIPS
This trial studies whether taking rifaximin plus lactulose can prevent a brain problem called hepatic encephalopathy (confusion) after TIPS, a procedure to reduce pressure in the liver. It may help people who are having TIPS planned and are at risk of this complication.
LeuvenAges 18–80 - NCT04073797Recruiting
PET scan study of inflammation and cholesterol-lowering treatment
This study uses PET/CT and related scans to measure inflammation in artery plaque and how cholesterol-lowering treatment changes it. It may help researchers understand which treatments reduce artery inflammation for people with heart or blood-vessel disease and high LDL (“bad”) cholesterol.
CambridgeAges 18–99 - NCT04074135RecruitingPhase 2
Study of pancreatic tumors in people with VHL
This trial studies the natural course and management of pancreatic neuroendocrine tumors in people with von Hippel–Lindau (VHL) disease. It may help doctors better predict how these pancreatic findings change over time and how to manage them.
Bethesda, MarylandAges 12 years+ - NCT04075084Recruiting
Watching outcomes of routine home monitoring after a heart monitor implant
This registry study follows people who get a BIOTRONIK implantable heart monitor and use home monitoring. It looks at how routine care and at-home check-ins work in real life, which may help improve support and tracking over time.
AdelaideAges 18 years+
Common questions
- How many brain & nervous system clinical trials are recruiting?
- Clin2 is tracking 12,425 recruiting neurology studies from the U.S. registry right now, out of 19,436 we cover in this area in total.
- What does “Brain & nervous system” cover here?
- Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We group each study into brain & nervous system based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a brain & nervous system trial near me?
- Use the search to filter brain & nervous system studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.