Neurology
Brain & nervous system clinical trials
Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We’re tracking 12,413 recruiting studies in this area right now.
By phase
- Not applicable9,750
- Phase 2784
- Phase 1574
- Phase 3535
- Phase 4342
- Phase 1/Phase 2305
- Phase 2/Phase 3123
Top conditions
- Stroke845
- Parkinson Disease426
- Multiple Sclerosis343
- Alzheimer Disease341
- Dementia226
- Ischemic Stroke200
- Epilepsy197
- Obstructive Sleep Apnea155
- Spinal Cord Injuries154
- Insomnia153
- Sarcopenia149
- Traumatic Brain Injury149
- Acute Ischemic Stroke139
- Cerebral Palsy131
- Mild Cognitive Impairment129
- Pain Management114
- Migraine112
- Amyotrophic Lateral Sclerosis108
Leading sponsors
- Beijing Tiantan Hospital133
- Riphah International University125
- Assistance Publique - Hôpitaux de Paris112
- Mayo Clinic99
- Xuanwu Hospital, Beijing94
- VA Office of Research and Development93
- Hospices Civils de Lyon79
- Johns Hopkins University70
- National Taiwan University Hospital70
- University of Minnesota64
Where studies are running
- California678
- Massachusetts300
- New York291
- Florida275
- Texas266
- Maryland245
- Arizona213
- Alabama210
- Illinois188
- Pennsylvania178
Recruiting studies12,411 total
- NCT07398170Recruiting
Searching for tumor cells in fluid for recurrent meningioma
This study looks for tumor cells in your blood or spinal fluid to see if they can help track aggressive meningiomas that have come back. It may help doctors understand your cancer better and guide future treatments.
Montpellier, FranceAges 18 years+ - NCT05950659Recruiting
Wearable insoles to prevent repeat diabetic foot ulcers
This trial tests special sensory insoles (called Orpyx Sensory Insoles) to help prevent diabetic foot ulcers from coming back. It aims to reduce high-pressure foot spots for people who already had a healed nerve-related ulcer.
Baltimore, MarylandAges 18 years+ - NCT07703020Enrolling by invitation
Obesity in PKU patients
This study looks at how common obesity is in adults with PKU and what factors may contribute to it.
Lausanne, Canton of VaudAges 18 years+ - NCT07247279Recruiting
Study of myasthenia gravis treatments in Russia
This study tracks how generalized myasthenia gravis (a condition that causes muscle weakness) is treated in Russia. By looking at real-world data, researchers hope to learn more about which treatments work best for people like you.
Kazan'Ages 18 years+ - NCT05957913Enrolling by invitationPhase 2
Testing antiviral drugs to control Epstein-Barr virus in MS
This Phase 2 study tests whether certain antiviral medicines can reduce Epstein-Barr virus (EBV) activity. If you have multiple sclerosis and evidence of EBV infection, the results may help clarify new ways to target EBV-related disease activity.
Boston, MassachusettsAges 18 years+ - NCT07008989Recruiting
Phone app to improve memory in Down syndrome
This study tests a smartphone app called HippoCamera to see if it can help teenagers and young adults with Down syndrome remember everyday events better. You would use the app at home with some help from a parent or guardian.
Chestnut Hill, MassachusettsAges 15–35 - NCT05989893Recruiting
Mapping human thinking during brain surgery
This study maps how thinking works in people with epilepsy or brain lesions near important brain areas. It involves testing during brain surgery procedures to help researchers understand healthy brain function.
Houston, TexasAges 18–75 - NCT07588932RecruitingEarly Phase 1
Medication and Robot Training for Stroke Arm Recovery
This study tests whether three medications (Telmisartan, Cilostazol, and Metformin) combined with robotic arm training can help people improve arm movement and strength after a chronic stroke. You would participate in supervised training sessions using a robotic rehabilitation system.
Charlestown, MassachusettsAges 21–80 - NCT05184816RecruitingPhase 1
Deferoxamine for leptomeningeal cancer spread in the brain lining
This Phase 1 study tests deferoxamine, a medicine given directly into spinal fluid, for leptomeningeal metastasis (cancer spreading to the brain and spinal cord lining). It’s meant to see whether the treatment can be safely given and whether it may help control this difficult-to-treat cancer location.
Basking Ridge, New JerseyAges 18 years+ - NCT07047326Recruiting
Urokinase for acute ischemic stroke within 6 hours
This trial tests whether the clot-busting drug urokinase can help people who have had an ischemic stroke (a stroke caused by a blood clot). The goal is to dissolve the clot and improve recovery, as long as treatment starts within 6 hours of the first symptoms.
Beijing, Beijing MunicipalityAges 18–80 - NCT05854433Enrolling by invitation
Study brain structure in adults with muscle weakness
This study uses scans and other tests to understand how brain structure relates to symptoms in people with myotonic dystrophy type 1 or type 2. It may help researchers connect measurable brain changes to movement and other clinical outcomes.
Winston-Salem, North CarolinaAges 30–65 - NCT07703462Enrolling by invitationPhase 1/Phase 2
Personalized therapy for TARDBP ALS
This trial offers a custom-made treatment for people with ALS caused by a TARDBP gene mutation. It uses a personalized medicine approach to target the specific genetic cause of the disease.
Philadelphia, PennsylvaniaAges Any age - NCT07698925Recruiting
Breathing exercises for sleep problems in PCOS
This trial tests if simple diaphragmatic breathing exercises can improve sleep for women with Polycystic Ovarian Syndrome (PCOS) who have trouble sleeping. If you have PCOS and poor sleep, this gentle, non-drug approach might help.
Cairo, Cairo GovernorateAges 25–35 - NCT05904132Recruiting
Brain stimulation therapy for early Alzheimer’s memory loss
This trial studies a “closed-loop” brain stimulation approach to improve symptoms in people with early Alzheimer’s-related memory problems. It may help by delivering stimulation based on your brain signals, if you meet the safety and diagnosis requirements.
Charlestown, MassachusettsAges 50–80 - NCT06564896Recruiting
Comparing sleep apnea treatments (CPAP vs alternatives)
This trial compares different positive airway pressure (PAP) machines to see which works best for people with moderate to severe sleep apnea. If you have been diagnosed but haven't used a CPAP yet, this study may help find the best option for you.
Cheras, Kuala LumpurAges 18 years+ - NCT04007380Recruiting
Sleep problems after spinal cord injury study
This study looks at how sleep-disordered breathing (breathing problems during sleep) affects mood, thinking, and behavior after a spinal cord injury. It may help researchers understand the impact of these sleep breathing issues and guide better support for people after injury.
Toronto, OntarioAges 18 years+ - NCT04010214Recruiting
Study of cerebellar ataxia in Southeast China
This is an observational study that follows people with cerebellar ataxia, their relatives, and healthy volunteers to learn more about the condition. It may help researchers better understand the causes and patterns of cerebellar ataxia over time.
Fuzhou, FujianAges Any age - NCT04007432Recruiting
Testing nighttime low-oxygen levels after hip fracture surgery
This study checks how often older adults get low oxygen during the night after hip fracture surgery. It may help doctors better monitor and improve care during hospital recovery.
ParisAges 70 years+ - NCT04008329Recruiting
Study of people with amyotrophic lateral sclerosis
This study follows people living with amyotrophic lateral sclerosis (ALS) over time. It may help researchers better understand ALS and track changes that could guide future treatments.
Fuzhou, FujianAges Any age - NCT04010604Recruiting
Study of spinal muscular atrophy in patients and carriers
This is a long-term observation study that follows people affected by spinal muscular atrophy (SMA), people who carry the SMA gene but have no symptoms, and families of people with SMA. It helps researchers better understand SMA and related genetic status, which can support future treatment planning.
Fuzhou, FujianAges 1 week–70 years - NCT04010188Recruiting
Study comparing people with Charcot-Marie-Tooth and healthy controls
This study follows people who have Charcot-Marie-Tooth disease (CMT) and compares them with people without it. It aims to better understand CMT, using both clinical symptoms and genetic test results, which may help future care.
FuzhouAges Any age - NCT04012671Recruiting
Study of Duchenne muscular dystrophy in children and carriers
This is a research study that follows people with Duchenne muscular dystrophy and female genetic carriers to better understand the condition. It may help researchers measure health patterns over time, which can support future treatments.
FuzhouAges 2 years+ - NCT04011566Recruiting
Testing a shunt sensor in people with symptom-free hydrocephalus shunts
This study checks how well a device called ShuntCheck works for monitoring a ventriculoperitoneal (VP) shunt in people who feel okay (no symptoms) with normal pressure hydrocephalus. It may help improve future shunt checks during routine care.
Tampa, FloridaAges 40 years+ - NCT04012905RecruitingPhase 3
Compare two steroid taper schedules for giant cell arteritis
This Phase 3 study compares how two standard steroid dose-reduction (tapering) schedules work for people with giant cell arteritis. It aims to see which taper approach controls the disease while reducing problems from long-term steroid use.
CaenAges 50 years+
Common questions
- How many brain & nervous system clinical trials are recruiting?
- Clin2 is tracking 12,413 recruiting neurology studies from the U.S. registry right now, out of 19,419 we cover in this area in total.
- What does “Brain & nervous system” cover here?
- Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We group each study into brain & nervous system based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a brain & nervous system trial near me?
- Use the search to filter brain & nervous system studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.