Neurology
Brain & nervous system clinical trials
Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We’re tracking 12,425 recruiting studies in this area right now.
By phase
- Not applicable9,762
- Phase 2784
- Phase 1574
- Phase 3535
- Phase 4342
- Phase 1/Phase 2305
- Phase 2/Phase 3123
Top conditions
- Stroke845
- Parkinson Disease426
- Multiple Sclerosis343
- Alzheimer Disease341
- Dementia226
- Ischemic Stroke200
- Epilepsy197
- Obstructive Sleep Apnea155
- Spinal Cord Injuries154
- Insomnia153
- Sarcopenia149
- Traumatic Brain Injury149
- Acute Ischemic Stroke139
- Cerebral Palsy131
- Mild Cognitive Impairment129
- Pain Management114
- Migraine112
- Amyotrophic Lateral Sclerosis108
Leading sponsors
- Beijing Tiantan Hospital133
- Riphah International University125
- Assistance Publique - Hôpitaux de Paris112
- Mayo Clinic99
- Xuanwu Hospital, Beijing94
- VA Office of Research and Development93
- Hospices Civils de Lyon79
- Johns Hopkins University70
- National Taiwan University Hospital70
- University of Minnesota64
Where studies are running
- California678
- Massachusetts300
- New York292
- Florida275
- Texas267
- Maryland245
- Arizona213
- Alabama211
- Illinois189
- Pennsylvania178
Recruiting studies12,423 total
- NCT04233788Recruiting
Brain mass imaging study using MRI to learn what causes it
This study uses MRI scanning to better describe a suspected brain mass and understand what it might be. You may be asked to lie in the scanner for about one hour, if you meet the study’s safety and eligibility rules.
BernAges 18 years+ - NCT04236726Recruiting
Quality of life study for people with chronic breathing failure
This study looks at how chronic respiratory failure affects day-to-day quality of life. It enrolls people who use breathing support at home or in care, and may help clinicians understand what support works best for patients’ daily living.
LondonAges 18 years+ - NCT04240561Recruiting
Study of hearing aid results in people with Alzheimer’s dementia
This study looks at how much hearing aid outcomes vary in older adults who have Alzheimer’s dementia or mild memory problems. It may help researchers understand what hearing aids work best and for whom.
Chicago, IllinoisAges 50–90 - NCT04246437RecruitingPhase 1
Brain imaging study for autonomic failure with possible Parkinson disease
This Phase 1 study uses a special injected imaging tracer and an MRI scan to look at brain function in people with autonomic failure. It may help researchers understand what’s happening in conditions that can be related to Parkinson disease, multiple system atrophy, or dementia with Lewy bodies.
Nashville, TennesseeAges 18 years+ - NCT04250454Recruiting
Early treatment for babies at risk of cerebral palsy
This trial looks at an early intervention for very young babies who show signs they may develop cerebral palsy. The goal is to improve development as early as possible, especially in babies with concerning brain scan findings or movement patterns.
Charlottenlund, København CityAges 2 months–5 months - NCT04250493Recruiting
Testing insulin resistance in multiple system atrophy
This study looks at how the body handles blood sugar (insulin resistance) in people with multiple system atrophy (MSA). Results may help doctors understand the disease better and explore new ways to monitor or treat it.
BordeauxAges 30 years+ - NCT04253015Recruiting
Safety registry for people with high-risk neuroblastoma on dinutuximab beta
This study is a long-term safety and follow-up registry. It tracks how dinutuximab beta is doing in real-world patients with high-risk neuroblastoma over time.
Vienna, State of ViennaAges 1–18 - NCT04252066Recruiting
Pregnancy and breastfeeding study for women with Fabry disease
This study follows pregnant and breastfeeding women with Fabry disease (and their infants) to better understand what happens during pregnancy and early life. You may or may not be taking migalastat, and the goal is to gather real-world information that could help future care.
Philadelphia, PennsylvaniaAges Any age - NCT04263285Recruiting
Repetitive brain stimulation for depression after spinal cord injury
This trial studies a brain-stimulation treatment to improve depression symptoms in people who have depression after a spinal cord injury. It may help if you have major depression and meet specific safety and eligibility checks.
Charleston, South CarolinaAges 18–70 - NCT04271033Recruiting
MicroNet-covered stent to prevent stroke in carotid procedures
This study tests a special stent (a small mesh tube) that may help prevent stroke during a carotid revascularization procedure. It’s for people with narrowing in the carotid artery, either recently symptomatic or very high-grade even without symptoms.
Krakow, MaloplskaAges 18 years+ - NCT04274179RecruitingPhase 3
Ketogenic diet for children with new childhood absence seizures
This trial tests whether a high-fat, low-carbohydrate (ketogenic) diet can reduce absence seizures in children who are newly diagnosed. It may help some kids by changing how the brain uses energy, but participation requires close diet monitoring and follow-up.
Baltimore, MarylandAges 3–12 - NCT04271878Recruiting
Test breathing and blood-pressure response in POTS patients
This study measures how breathing patterns and heart rate/blood pressure change when you move from lying to standing in people with POTS. It may help researchers understand symptoms better and improve ways to manage them.
Calgary, AlbertaAges 18–60 - NCT04273828Recruiting
Study of muscle changes in chronic low back pain surgery
This study looks at how muscle degeneration relates to nerve-related symptoms in people with chronic low back pain. You may be eligible if you’ve tried non-surgical care but still need surgery to relieve nerve pressure.
São Paulo, São PauloAges 18 years+ - NCT04278118Recruiting
Proton radiation study for non-cancer brain tumor types
This trial tests a radiation plan that gives treatment in fewer, larger “fractions” using proton beams (or sometimes photon beams) for certain non-cancer brain tumor types. It aims to see how well this approach works while keeping side effects manageable.
Atlanta, GeorgiaAges 18 years+ - NCT04279158Recruiting
Attention training after stroke or for ADHD
This study tests an attention-focused training approach to help people improve how the brain inhibits or filters information. It may be relevant after certain stroke-related attention problems, and also for people with ADHD, or for healthy volunteers for comparison.
BronAges 8–75 - NCT04282629RecruitingPhase 2
Milrinone to help prevent brain blood-flow complications after aneurysm bleed
This Phase 2 trial tests whether milrinone, a heart-acting medicine, can improve brain blood flow to help prevent delayed brain ischemia after a severe subarachnoid hemorrhage. It may help reduce later brain damage in people who are too ill or sedated for a normal neurologic exam early on.
BordeauxAges 18 years+ - NCT04286308Recruiting
Testing brain-speech recordings during DBS for movement disorders
This study looks at how brain and speech networks work while people with Parkinson’s disease, essential tremor, or dystonia are getting deep brain stimulation (DBS). It may help doctors better understand and possibly improve speech outcomes for people receiving DBS.
Boston, MassachusettsAges 18–85 - NCT04286516Recruiting
Brain and robot training for arm movement after stroke
This study tests whether brain stimulation and robotic/arm training can improve arm movement in people who had a stroke. It may help strengthen movement and coordination by targeting brain pathways related to arm control.
Pittsburgh, PennsylvaniaAges 45–90 - NCT04289467RecruitingPhase 2
Fenfluramine for stubborn infantile spasms
This Phase 2 trial studies fenfluramine to treat infantile spasms that haven’t improved after standard medicines (ACTH and vigabatrin). If you/your child has ongoing seizures, the study may offer another treatment option and will monitor safety closely, especially heart-related side effects.
Los Angeles, CaliforniaAges 1–3 - NCT04289142RecruitingPhase 4
Testing memory effects of dexmedetomidine during heart surgery
This study looks at how a sleep medicine called dexmedetomidine affects thinking and memory after heart surgery. It compares cognitive outcomes over time to see if this sedation choice changes long-term brain function.
Vancouver, British ColumbiaAges 60 years+ - NCT04296604Recruiting
tDCS brain stimulation to improve thinking and mood
This study tests whether a non-surgical brain stimulation called tDCS can improve “executive function,” which means skills like planning, focus, and decision-making. It is designed for people with several mental health and substance-use conditions, and it may help you if those skills are affected by your diagnosis.
Boston, MassachusettsAges 18–65 - NCT04296097Recruiting
Deep brain stimulation for severe, steady disabling tinnitus
This study tests whether deep brain stimulation (a device that sends controlled signals to the brain) can reduce severe, constant tinnitus that has not improved with usual treatments. It may help lower the loudness distress and improve daily quality of life for people whose tinnitus is especially disabling.
GrenobleAges 18–75 - NCT04299893RecruitingPhase 2/Phase 3
Ozone treatment for chemotherapy nerve pain
This trial tests whether ozone therapy can reduce painful nerve damage caused by chemotherapy. It is for adults with ongoing moderate-to-severe pain in the hands or feet after chemotherapy.
Las Palmas de Gran Canaria, Las PalmasAges 18–100 - NCT04302870RecruitingPhase 2/Phase 3
Test medicines for motor neurone disease using adaptive trial design
This study tests treatments for motor neurone disease (MND) and assigns people to different treatment arms in an adaptive way. It may help doctors find out which medicine works best and for whom.
Portadown, County ArmaghAges 18 years+
Common questions
- How many brain & nervous system clinical trials are recruiting?
- Clin2 is tracking 12,425 recruiting neurology studies from the U.S. registry right now, out of 19,436 we cover in this area in total.
- What does “Brain & nervous system” cover here?
- Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We group each study into brain & nervous system based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a brain & nervous system trial near me?
- Use the search to filter brain & nervous system studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.