Neurology
Brain & nervous system clinical trials
Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We’re tracking 12,425 recruiting studies in this area right now.
By phase
- Not applicable9,762
- Phase 2784
- Phase 1574
- Phase 3535
- Phase 4342
- Phase 1/Phase 2305
- Phase 2/Phase 3123
Top conditions
- Stroke845
- Parkinson Disease426
- Multiple Sclerosis343
- Alzheimer Disease341
- Dementia226
- Ischemic Stroke200
- Epilepsy197
- Obstructive Sleep Apnea155
- Spinal Cord Injuries154
- Insomnia153
- Sarcopenia149
- Traumatic Brain Injury149
- Acute Ischemic Stroke139
- Cerebral Palsy131
- Mild Cognitive Impairment129
- Pain Management114
- Migraine112
- Amyotrophic Lateral Sclerosis108
Leading sponsors
- Beijing Tiantan Hospital133
- Riphah International University125
- Assistance Publique - Hôpitaux de Paris112
- Mayo Clinic99
- Xuanwu Hospital, Beijing94
- VA Office of Research and Development93
- Hospices Civils de Lyon79
- Johns Hopkins University70
- National Taiwan University Hospital70
- University of Minnesota64
Where studies are running
- California678
- Massachusetts300
- New York292
- Florida275
- Texas267
- Maryland245
- Arizona213
- Alabama211
- Illinois189
- Pennsylvania178
Recruiting studies12,423 total
- NCT04192656RecruitingPhase 4
PAP treatment for sudden hearing loss with sleep apnea
This trial tests whether using PAP (a breathing device for sleep apnea) can improve sudden hearing loss that happens alongside obstructive sleep apnea. It may help by reducing stress on the body during sleep and supporting hearing recovery.
Beijing, Beijing MunicipalityAges 18–70 - NCT04192773RecruitingEarly Phase 1
Brain-scan study of IV lidocaine for tinnitus
This early study uses an MRI/brain scan to see how IV lidocaine affects brain activity in people with tinnitus, and also compares it with people without tinnitus or with different hearing patterns. It may help researchers understand whether lidocaine could change tinnitus signals in the brain.
Boston, MassachusettsAges 18 years+ - NCT04194619Recruiting
Study of pregnancy safety in women with rare blood-vessel diseases
This study looks at pregnancy and the early period after birth in women with rare diseases that affect blood vessels. It may help doctors understand risks and improve care for future pregnancies.
AngersAges 18–45 - NCT04197297RecruitingPhase 2
Brain scan tests for biomarkers in people with brain metastases
This trial studies brain scan findings to see if specific imaging markers can help understand or predict outcomes in people with brain metastases. It may help researchers improve how brain metastases are evaluated before radiation treatment.
Toronto, OntarioAges 18 years+ - NCT04197258Recruiting
Peer support after stroke for people going home from rehab
This study tests whether a personal “peer” supporter can help you after discharge home following a stroke. It’s meant to improve how stroke patients cope and to understand what support works best.
Saint-Genis-LavalAges 18 years+ - NCT04198909Recruiting
Testing a new way to measure hearing nerve health
This study uses a painless, non-invasive method to test how well the hearing nerve works in people with normal hearing. It may help doctors better understand hearing loss in the future.
Clermont-FerrandAges 18–55 - NCT04198246Recruiting
Chinese essential tremor registry study
This study is a registry for people diagnosed with essential tremor, helping doctors collect and compare information over time. It may help improve understanding of essential tremor and guide future care.
Changsha, HunanAges Any age - NCT04198792Recruiting
Finding outcomes after ECMO for heart-related emergencies
This study looks at what helps determine survival and better brain function after people are treated with ECMO, a heart-lung support machine. It may help doctors understand who is most likely to do well after this kind of emergency treatment.
GothenburgAges 16 years+ - NCT04199299Recruiting
Communication sensors for people who can’t express needs clearly
This trial tests a wearable sensor system that may help people who have difficulty communicating their needs clearly. It may capture signals from the body so caregivers and devices can better understand reactions and needs.
OsloAges 5–80 - NCT04204863Recruiting
Study of adults treated for a prolonged seizure emergency
This study looks at adults who had a serious, long-lasting seizure emergency called status epilepticus. It aims to better understand what happened and may help improve care for similar patients in the future.
AarauAges 18 years+ - NCT04202341Recruiting
Registry for people with generalized myasthenia gravis on Alexion treatment
This study is a registry, meaning it collects health and disease information from people with generalized myasthenia gravis (gMG) who are receiving Alexion C5 “inhibition” therapies. Your data can help researchers better understand real-world outcomes and disease patterns over time.
Birmingham, AlabamaAges 18 years+ - NCT04201964Recruiting
TNK treatment for stroke when blood flow didn’t reopen enough
This trial looks at giving a clot-busting medicine directly into the brain arteries (intra-arterial TNK) when a stroke procedure (thrombectomy) doesn’t reopen the blocked vessel enough. It aims to improve recovery by improving blood flow while checking for safety, especially bleeding risk.
ShenyangAges 18 years+ - NCT04204642Recruiting
Testing MRI findings to find markers of brain blood vessel disease
This study looks at brain MRI scans in people with cerebral amyloid angiopathy (a condition where amyloid builds up in brain blood vessels). The goal is to search for “biomarkers,” or measurable scan features, to better understand and detect the disease in some people before symptoms or during symptoms.
Milan, MilanoAges 55 years+ - NCT04212780Recruiting
Testing a smarter DBS system for severe essential tremor
This trial tests an upgraded deep brain stimulation (DBS) system that can “sense” tremor and adjust treatment in a loop. It’s designed for people with severe essential tremor whose tremor is still disabling despite standard DBS and medication.
Gainesville, FloridaAges 21–99 - NCT04215679Recruiting
Virtual reality plus mental practice for stroke hand recovery
This trial tests whether “motor imagery” done with virtual reality can improve hand function after a stroke. You may benefit if you have readable Turkish and enough thinking ability to follow the program.
Bolu, MerkezAges 18–80 - NCT04217421RecruitingPhase 3
Allopurinol for newborns needing heart surgery with bypass
This trial tests whether the medicine allopurinol can protect the brain and heart in newborns with serious congenital heart disease who need heart surgery soon after birth. It may help reduce injury during and around surgery that uses a heart-lung machine (cardiopulmonary bypass).
GroningenAges Up to 1 month - NCT04219670Recruiting
Using sensors to study stroke recovery in hospital and community
This study uses sensor recordings to learn how stroke recovery happens over time, including for people in the hospital and those living in the community. Your results may help improve future monitoring and rehabilitation after stroke.
Chicago, IllinoisAges 18 years+ - NCT04220047Recruiting
Surgery changes for preventing irregular heart rhythms during bypass
This trial studies whether removing a small heart pouch area and a specific ligament during off-pump heart bypass surgery improves outcomes. It is meant for people having their first off-pump coronary bypass, without a history of atrial fibrillation.
BeijingAges 18–80 - NCT04220190RecruitingPhase 2/Phase 3
Study drug made from your immune cells for ALS
This trial tests RAPA-501, a treatment made using your own immune cells, to slow progression of ALS. It may help by changing how your immune system responds in ALS.
Boston, MassachusettsAges 18 years+ - NCT04222062RecruitingPhase 2
Compare Gliadel implant versus focused brain radiation
This Phase 2 study compares two ways to treat brain metastases: a Gliadel wafer placed during planned surgery versus focused stereotactic radiosurgery. It aims to see which approach works better and is safer for people with a limited number of brain tumor spots.
Detroit, MichiganAges 18 years+ - NCT04225975Recruiting
Study brain activity in babies right after birth
This study measures a newborn’s brain activity immediately after delivery. It may help doctors better understand early brain function in healthy full-term babies.
AmiensAges 1 minute–15 minutes - NCT04229056Recruiting
Computer training to improve thinking and planning after stroke or Parkinson’s
This trial tests computer-based “self-training” to improve executive function, such as working memory—your ability to hold and use information in mind. It’s for adults with a prior stroke, cardiac arrest, or Parkinson’s disease who have trouble on a specific working-memory task.
CopenhagenAges 18–100 - NCT04230785Recruiting
Blood RNA test during clot-busting treatment for stroke
This trial studies special molecules in the blood (non-coding RNA) in people having an acute ischemic stroke treated with a procedure to remove clots. It may help doctors better understand how the body responds and potentially improve future stroke care.
Nanjing, JiangsuAges 18–90 - NCT04230447Recruiting
Study of brain confusion in sepsis patients
This study builds a group of adults with sepsis who develop sudden brain problems, like delirium or coma. It aims to better understand how often this happens and how it may be recognized in hospital, which could help future care.
Beijing, Beijing MunicipalityAges 18–89
Common questions
- How many brain & nervous system clinical trials are recruiting?
- Clin2 is tracking 12,425 recruiting neurology studies from the U.S. registry right now, out of 19,436 we cover in this area in total.
- What does “Brain & nervous system” cover here?
- Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We group each study into brain & nervous system based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a brain & nervous system trial near me?
- Use the search to filter brain & nervous system studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.