Neurology
Brain & nervous system clinical trials
Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We’re tracking 11,952 recruiting studies in this area right now.
By phase
- Not applicable9,355
- Phase 2761
- Phase 1558
- Phase 3514
- Phase 4339
- Phase 1/Phase 2300
- Phase 2/Phase 3125
Top conditions
- Stroke798
- Parkinson Disease395
- Alzheimer Disease338
- Multiple Sclerosis328
- Dementia226
- Epilepsy193
- Ischemic Stroke190
- Insomnia159
- Traumatic Brain Injury151
- Obstructive Sleep Apnea142
- Spinal Cord Injuries142
- Acute Ischemic Stroke138
- Sarcopenia134
- Mild Cognitive Impairment127
- Cerebral Palsy119
- Pain Management116
- Migraine107
- Fibromyalgia104
Leading sponsors
- Beijing Tiantan Hospital124
- Assistance Publique - Hôpitaux de Paris109
- Riphah International University105
- Mayo Clinic98
- VA Office of Research and Development92
- Xuanwu Hospital, Beijing89
- Hospices Civils de Lyon77
- Johns Hopkins University69
- University of Minnesota63
- Washington University School of Medicine63
Where studies are running
- California661
- Massachusetts305
- New York295
- Florida272
- Texas266
- Maryland248
- Alabama207
- Arizona206
- Illinois181
- Pennsylvania177
Recruiting studies11,952 total
- NCT06772220Recruiting
Homocysteine management for Parkinson's patients on levodopa
This trial tests whether controlling homocysteine levels can help people with Parkinson's disease who are taking levodopa. You may qualify if you take at least 300 mg of levodopa per day, are between 40 and 90 years old, and have no major kidney problems or uncontrolled high blood pressure.
Portland, OregonAges 40–90 - NCT05634967Recruiting
Kesimpta pregnancy registry for pregnant people with MS
This registry collects information about pregnancy outcomes in people with multiple sclerosis (MS) who have taken Kesimpta (ofatumumab) during pregnancy or shortly before it. It may help doctors better understand safety and developmental outcomes for babies.
La Jolla, CaliforniaAges 18–100 - NCT06085300Recruiting
Bilingual treatment study for children with language delays
This study looks at how bilingual children with language delays respond to treatment in English or Spanish. It aims to find the best way to help them improve their language skills.
Houston, TexasAges 4–6 - NCT06679816RecruitingPhase 4
Hydrocortisone for hormone replacement in large pituitary tumor surgery
This trial tests hydrocortisone as hormone replacement therapy after surgery for large pituitary tumors. It aims to help patients maintain healthy cortisol levels during recovery.
Beijing, Beijing MunicipalityAges 18–70 - NCT06665113Recruiting
Ear nerve stimulation for early Parkinson's disease
This trial tests whether a non-invasive nerve stimulation device (taVNS) worn on the ear can protect brain cells and slow Parkinson's disease progression in early-stage patients. It is for people who have been diagnosed within the last 3 years and are already on standard medication.
Nanjing, JiangsuAges 55–75 - NCT06759116Recruiting
Comparing two pain medicines for knee surgery recovery
This trial tests whether adding fentanyl or dexmedetomidine to a standard numbing medicine (bupivacaine) provides better pain relief after knee surgery. It may help find the best option for patients undergoing knee procedures like total knee replacement or ACL repair.
El SharkiaAges 21–85 - NCT06509191RecruitingPhase 2/Phase 3
Melatonin for preventing delirium in older hospital patients
This trial tests if giving melatonin (a natural sleep hormone) can help prevent delirium (sudden confusion) in older adults who are hospitalized. It may help you if you are 65 or older and admitted to the hospital for general medical care.
MuscatAges 65 years+ - NCT06773286Recruiting
Stimulation and therapy for hand function after spinal cord injury
This trial is testing a safe method of electrical stimulation through the skin (called transcutaneous stimulation) combined with physical therapy to help people who recently had a cervical spinal cord injury improve hand and arm function. It is designed for people who are still in the hospital rehab setting.
West Orange, New JerseyAges 18–75 - NCT06773988Recruiting
Long-term monitoring of breathing support at home for Duchenne patients
This study follows adults with Duchenne muscular dystrophy who use a breathing machine (non-invasive ventilation or NIV) at home. It aims to track their health over time to improve care.
Leuven, Vlaams-BrabantAges 18 years+ - NCT06775028Recruiting
Integrated care for older adults with atrial fibrillation
This trial is testing a new approach to care for older adults with atrial fibrillation (an irregular heartbeat) who also have other health conditions. It aims to see if a more integrated, team-based care plan helps improve their overall health and quality of life.
HaskovoAges 65 years+ - NCT06530732RecruitingPhase 3
Neck drainage surgery for Alzheimer's disease
This study tests a new surgical treatment for Alzheimer's disease. The surgery aims to improve drainage in the neck to help clear waste from the brain. This is a first-of-its-kind pilot study to see if it is safe and might help thinking and memory.
Hangzhou, ZhejiangAges Any age - NCT07482176RecruitingPhase 3
Gene therapy trial for wet age-related macular degeneration
This trial tests a one-time gene therapy injection (IXO-vec) for people with wet age-related macular degeneration (nAMD). It aims to reduce the need for frequent eye injections by helping the eye make its own medicine to block the growth of harmful blood vessels.
Mesa, ArizonaAges 50 years+ - NCT07485244Recruiting
EEG brain monitoring in ICU patients at risk for delirium
This study uses a simple headband (EEG) to monitor brain activity in ICU patients who are at high risk for delirium. The goal is to see if the EEG can help detect delirium earlier, so doctors can provide better care.
Nashville, TennesseeAges 18 years+ - NCT07486934RecruitingPhase 3
Study of DYNE-101 for Myotonic Dystrophy Type 1
This trial tests an experimental drug called DYNE-101 to see if it can help people with myotonic dystrophy type 1 (DM1). The study aims to improve muscle function and daily life. It is for adults who can walk and stand up from a chair without help.
La Jolla, CaliforniaAges 16 years+ - NCT07484217RecruitingPhase 3
Testing solriamfetol for depression with daytime sleepiness
This study tests if the drug solriamfetol can help people with major depression who also feel very tired during the day. It aims to improve both mood and daytime sleepiness.
Tucson, ArizonaAges 18–65 - NCT07484022RecruitingPhase 1
A new drug added to standard treatment for advanced bladder cancer
This trial adds an investigational drug, GB-4362, to a standard combination of two medicines (enfortumab vedotin and pembrolizumab) for advanced bladder cancer. The study wants to see if adding this drug is safe and helps treat the cancer better.
Duarte, CaliforniaAges 18 years+ - NCT04956185Recruiting
Collecting hospital data from people with stroke
This study collects information from people admitted to the stroke care team or neurology during their hospital stay. It may help improve stroke care by understanding patient conditions and hospital experiences.
Ghent, FlandersAges Any age - NCT06019637Recruiting
Long-term safety study of Zolgensma for spinal muscular atrophy
This study follows the long-term safety of Zolgensma gene therapy in Brazilian children with spinal muscular atrophy (SMA). It helps doctors understand how safe the treatment is over time.
Curitiba, ParanáAges birth–100 years - NCT07488429Recruiting
Brain stimulation plus therapy for leg function in cerebral palsy
This study tests whether combining a gentle brain stimulation treatment (rTMS) with physical therapy can help improve leg movement and reduce muscle stiffness in children with cerebral palsy. The goal is to see if this combination works better than therapy alone.
AnkaraAges 5–18 - NCT07486882Recruiting
Comparing two insomnia treatments: sound therapy vs. cognitive behavioral therapy
This study compares a new sound-based therapy (Acoustic Resonance Therapy) using a headband to standard cognitive behavioral therapy for insomnia. It aims to see which approach helps people with moderate-to-severe insomnia sleep better.
Rochester, MinnesotaAges 22 years+ - NCT07488468Recruiting
Shortening fasting before planned surgery
This trial tests a program to reduce how long patients must fast before elective surgery. Shorter fasting may make patients more comfortable and could help recovery.
GiessenAges Any age - NCT07488806Recruiting
Understanding Nemaline Myopathy Over Time (Spain)
This study follows people with nemaline myopathy over time to better understand how the disease progresses. It helps researchers learn more about the condition and plan future treatments.
BarcelonaAges Any age - NCT07482579Recruiting
Stroke Recovery Prediction Using a Digital Twin
This study uses digital twin technology to predict how well people will recover after a stroke. It looks at your walking ability and other factors to create a personalized recovery plan.
Gyeonggi-do, Gyeonggi-doAges 20 years+ - NCT07481786RecruitingPhase 3
Bevacizumab with focused radiation vs standard brain radiation for lung cancer with brain spread
This trial tests combining a drug called bevacizumab with a focused radiation treatment for people with lung cancer that has spread to the brain. It compares this to the standard radiation approach, and aims to see which better preserves memory and controls tumors.
Chongqing, Chongqing MunicipalityAges 18 years+
Common questions
- How many brain & nervous system clinical trials are recruiting?
- Clin2 is tracking 11,952 recruiting neurology studies from the U.S. registry right now, out of 18,491 we cover in this area in total.
- What does “Brain & nervous system” cover here?
- Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We group each study into brain & nervous system based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a brain & nervous system trial near me?
- Use the search to filter brain & nervous system studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.