Neurology
Brain & nervous system clinical trials
Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We’re tracking 11,952 recruiting studies in this area right now.
By phase
- Not applicable9,355
- Phase 2761
- Phase 1558
- Phase 3514
- Phase 4339
- Phase 1/Phase 2300
- Phase 2/Phase 3125
Top conditions
- Stroke798
- Parkinson Disease395
- Alzheimer Disease338
- Multiple Sclerosis328
- Dementia226
- Epilepsy193
- Ischemic Stroke190
- Insomnia159
- Traumatic Brain Injury151
- Obstructive Sleep Apnea142
- Spinal Cord Injuries142
- Acute Ischemic Stroke138
- Sarcopenia134
- Mild Cognitive Impairment127
- Cerebral Palsy119
- Pain Management116
- Migraine107
- Fibromyalgia104
Leading sponsors
- Beijing Tiantan Hospital124
- Assistance Publique - Hôpitaux de Paris109
- Riphah International University105
- Mayo Clinic98
- VA Office of Research and Development92
- Xuanwu Hospital, Beijing89
- Hospices Civils de Lyon77
- Johns Hopkins University69
- University of Minnesota63
- Washington University School of Medicine63
Where studies are running
- California661
- Massachusetts305
- New York295
- Florida272
- Texas266
- Maryland248
- Alabama207
- Arizona206
- Illinois181
- Pennsylvania177
Recruiting studies11,952 total
- NCT07465991Recruiting
Online insomnia therapy for fibromyalgia and activity
This study tests if an online therapy program for insomnia (using cognitive behavioral therapy, or CBT) can help people with fibromyalgia sleep better and be more physically active. If you have fibromyalgia and trouble sleeping, this treatment may improve your pain and daily function.
OxfordAges 18 years+ - NCT07466394Recruiting
Early detection of thinking problems study
This study tests a new way to find early signs of memory or thinking problems in older adults. It could help identify people who might benefit from earlier support or treatment.
MünchenAges 60 years+ - NCT07471555Enrolling by invitation
Vascular access and intraosseous study for nursing students
This trial tests a teaching method for inserting a special needle into bone (intraosseous access) and regular IV lines. It is only for 4th year nursing students.
Valencia, ValenciaAges 18 years+ - NCT07463027Enrolling by invitation
Veteran brain injury rehab with integrated care
This trial tests a 3-week rehabilitation program for veterans with traumatic brain injury and other conditions. It aims to improve recovery through team-based care.
Milwaukee, WisconsinAges 18–65 - NCT07463014Recruiting
Peer support for stroke recovery
This trial tests whether getting support from a trained peer coach who has also had a stroke can help you recover better. It's designed for people who have had a stroke and recently left the hospital.
SingaporeAges 21–99 - NCT07463235RecruitingPhase 3
High dose cabergoline for small prolactin tumors in women
This trial tests a higher dose of the drug cabergoline to see if it works better for small prolactin-secreting tumors (microprolactinomas) in premenopausal women who have not been treated before. It aims to find a safe and effective way to lower high prolactin levels and shrink the tumor.
Belo HorizonteAges 18 years+ - NCT06792396Recruiting
Study of children with a certain sleep-related seizure pattern
This research looks back at records of children (up to age 16) who were treated for a condition called electrical status epilepticus in sleep (ESES) or a related brain disorder with sleep-triggered abnormal brain waves. The goal is to learn more about these conditions to improve care.
ColchesterAges 1–16 - NCT06792201Recruiting
Sarcopenia study in women at different life stages
This trial looks at muscle loss (sarcopenia) in women who are pre-menopause or post-menopause, and whether hormone replacement therapy affects it. It aims to understand how muscle health changes over a woman's life.
BolognaAges 18–65 - NCT06790979Recruiting
Sleep patterns and recovery after traumatic brain injury
This study uses a wearable device to track sleep patterns in people who have had a traumatic brain injury (TBI). It aims to see how sleep relates to recovery, which could help improve care after a head injury.
Yinchuan, NingxiaAges 18–60 - NCT03360838Recruiting
Prediction test for confusion after heart surgery in older adults
This study uses a short, self-answered thinking test before elective heart surgery to help predict who may develop confusion afterward. The goal is to improve early identification and care planning for patients at higher risk.
BaselAges 60 years+ - NCT05618002Recruiting
Study compares sleep medicines for chronic pain insomnia
This trial tests different treatments to help people with long-term (chronic) pain and severe insomnia sleep better. It’s looking at three options—one medicine (lemborexant) compared with existing sleep medicines (zopiclone and clonidine)—and whether they improve sleep when non-medicine sleep strategies haven’t worked.
Surrey, British ColumbiaAges 20–99 - NCT04312399Recruiting
Hormone treatment study for Alzheimer risk in postmenopausal women
This study looks at whether hormone treatment can help prevent or slow Alzheimer’s disease in women who have gone through menopause. It may help by testing a hormone-based approach in a carefully selected group.
GhentAges 40–65 - NCT04748601RecruitingPhase 4
Qudexy XR to help prevent migraine in kids ages 6 to 11
This study tests whether Qudexy XR can reduce migraine headaches in children ages 6 to 11. It looks for kids who are having frequent, disruptive migraine attacks and checks safety with careful medication rules.
Birmingham, AlabamaAges 6–11 - NCT05864638Recruiting
Registry study of clot-removal treatment for acute stroke
This study records outcomes for people having an acute ischemic stroke treated with an endovascular (catheter-based) procedure. It may help doctors understand how clot-removal treatment works in different patients and hospitals.
ShanghaiAges Any age - NCT06102733Recruiting
Pelvic pain study for women and men
This trial is testing treatments for chronic pelvic pain, sacroiliac pain, groin pain, tailbone pain, and piriformis pain. It may help people with persistent pain in these areas find relief.
Surrey, British ColumbiaAges 20–99 - NCT06276543Recruiting
Safety study of the Bactiseal shunt catheter
This study is for people who already have a hydrocephalus shunt (a tube that drains fluid from the brain) and have had it for at least 2 years. It tests the safety of a specific catheter called Bactiseal and tracks how well it works over time.
Beijing, Beijing MunicipalityAges Any age - NCT06787677Recruiting
SPG pulsed radiofrequency for chronic cluster headache
This trial tests a treatment called sphenopalatine ganglion (SPG) pulsed radiofrequency for people with chronic cluster headache. It uses short bursts of energy to calm a nerve cluster in the face that is linked to the pain, and may help when standard medicines like verapamil or lithium haven't worked.
Beijing, Beijing MunicipalityAges 18 years+ - NCT06710249RecruitingPhase 2
Testing Salovum and SPC Flakes for Brain Tumor Swelling
This trial tests whether two special food products (Salovum and SPC Flakes) can help reduce brain swelling caused by tumors. If you have a brain tumor with swelling and are already on steroids, you may be able to join.
LundAges 18–79 - NCT06794879Recruiting
Parent survey on children's pain and sedation
This trial asks parents to fill out a survey about how their child's pain and sedation are managed during blood draws or other procedures. The goal is to understand parents' views and improve care for children.
Bologna, ItalyAges Any age - NCT06788288Recruiting
Massage chairs and sleep quality study
This study tests whether using a massage chair over several weeks can help improve sleep in people who have trouble sleeping. You may qualify if you have poor sleep and are otherwise healthy.
Trikala, ThessalyAges 18–45 - NCT06793865Recruiting
Stimulation for ankle muscles to improve balance after stroke
This study tests a type of electrical stimulation, called Russian current, on the front shin muscles to see if it helps stroke patients stand steadier and lower their risk of falling.
MinyaAges 40–55 - NCT06793332RecruitingPhase 2
Ivonescimab and Trodelvy for breast cancer with brain metastases
This trial tests two drugs (Ivonescimab and a Trop2 ADC) for people with triple-negative breast cancer that has spread to the brain. It aims to see if this combination can shrink brain tumors and help patients live longer.
Shanghai, Shanghai MunicipalityAges 18–70 - NCT06794736Recruiting
Study on metabolic profiles in lower-grade gliomas
This study looks at how lower-grade gliomas (a type of slow-growing brain tumor) use energy. It may help doctors better understand the tumor and choose the best treatment for you.
Bari, ApuliaAges 18 years+ - NCT06792877Recruiting
Mindfulness for thinking in early Alzheimer's
This study tests if mindfulness training can help protect thinking and memory in early-stage Alzheimer's disease. It compares mindfulness to other activities to see if it slows down memory loss.
Boston, MassachusettsAges 50–100
Common questions
- How many brain & nervous system clinical trials are recruiting?
- Clin2 is tracking 11,952 recruiting neurology studies from the U.S. registry right now, out of 18,491 we cover in this area in total.
- What does “Brain & nervous system” cover here?
- Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We group each study into brain & nervous system based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a brain & nervous system trial near me?
- Use the search to filter brain & nervous system studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.