Neurology
Brain & nervous system clinical trials
Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We’re tracking 12,425 recruiting studies in this area right now.
By phase
- Not applicable9,762
- Phase 2784
- Phase 1574
- Phase 3535
- Phase 4342
- Phase 1/Phase 2305
- Phase 2/Phase 3123
Top conditions
- Stroke845
- Parkinson Disease426
- Multiple Sclerosis343
- Alzheimer Disease341
- Dementia226
- Ischemic Stroke200
- Epilepsy197
- Obstructive Sleep Apnea155
- Spinal Cord Injuries154
- Insomnia153
- Sarcopenia149
- Traumatic Brain Injury149
- Acute Ischemic Stroke139
- Cerebral Palsy131
- Mild Cognitive Impairment129
- Pain Management114
- Migraine112
- Amyotrophic Lateral Sclerosis108
Leading sponsors
- Beijing Tiantan Hospital133
- Riphah International University125
- Assistance Publique - Hôpitaux de Paris112
- Mayo Clinic99
- Xuanwu Hospital, Beijing94
- VA Office of Research and Development93
- Hospices Civils de Lyon79
- Johns Hopkins University70
- National Taiwan University Hospital70
- University of Minnesota64
Where studies are running
- California678
- Massachusetts300
- New York292
- Florida275
- Texas267
- Maryland245
- Arizona213
- Alabama211
- Illinois189
- Pennsylvania178
Recruiting studies12,423 total
- NCT04589299RecruitingPhase 4
Subcutaneous immune globulin for newly diagnosed CIDP
This study tests whether giving immune globulin under the skin (SCIG) can help people with newly diagnosed CIDP. It may help improve muscle strength and nerve symptoms while avoiding the need for earlier IVIG/SCIG treatment.
AalborgAges 18 years+ - NCT04591093Recruiting
Tested deep vs shallow sound settings in cochlear implants
This study looks at how changing the “stimulation depth” (how deep the sound signals are delivered in the implant) affects hearing performance in people with cochlear implants. It may help find the best settings for improving hearing outcomes for suitable adults.
ParisAges 18 years+ - NCT04594837Recruiting
Robotic ankle device therapy after stroke-related foot drop
This study tests a robotic ankle device to help improve walking in people after a stroke who still have foot drop (the foot doesn’t lift well). It may help strengthen or retrain walking patterns during recovery.
Baltimore, MarylandAges 18 years+ - NCT04596852Recruiting
Testing a new stiffness and spasticity measuring method in children
This study checks whether a special device can reliably measure muscle stiffness and spasticity (tight, overactive muscles) in children. It includes children with cerebral palsy and healthy children to compare measurements and improve accuracy.
Saint-Fargeau-PonthierryAges 7–18 - NCT04600089RecruitingPhase 2
Ketamine during aortic surgery to help prevent spinal nerve injury
This Phase 2 study tests whether ketamine, given during a specific type of major aortic surgery, can help prevent spinal “nerve injury” (called spinal prophylaxis). You might be considered because your planned surgery and current plan for spinal protection match the trial’s needs.
Lexington, KentuckyAges 18–90 - NCT04603196Recruiting
Study sleep apnea in adults with multiple sclerosis
This study looks at how often sleep apnea happens in people who have multiple sclerosis, and how it affects daily life and health. You may be invited to participate if you’re an adult with a confirmed multiple sclerosis diagnosis and can consent to the study.
Boston, MassachusettsAges 18 years+ - NCT04602325Recruiting
Blood and brain injury biomarker study for inherited metabolic disorders
This trial studies blood and other measurable signs (biomarkers) that may reflect brain injury after certain inherited metabolic conditions. Results may help doctors better detect and understand brain effects from these illnesses, especially episodes that affect the brain.
Washington D.C., District of ColumbiaAges 7–18 - NCT04604041Recruiting
Study early warning signs in relapsing-remitting multiple sclerosis
This study looks at “subclinical markers,” meaning early or hidden body changes that may show how relapsing-remitting multiple sclerosis (MS) is doing even when symptoms seem mild. It may help researchers find better ways to monitor MS and detect changes sooner.
SplitAges 18–65 - NCT04604444Recruiting
Rehab program to improve speech brain plasticity after stroke
This study looks at how intensive therapy can change the brain’s ability to relearn speech after a stroke that caused language or speech planning problems. You may be a good candidate if your stroke-related aphasia or apraxia was diagnosed by a speech specialist about 7 months ago.
UppsalaAges 18–75 - NCT04606693Recruiting
Screening for sleep apnea before heart rhythm ablation
This study looks at whether checking for sleep apnea (breathing pauses during sleep) and treating it helps people prepare for atrial fibrillation ablation. It may help by improving outcomes for patients with atrial fibrillation who keep having episodes despite medication.
Madrid, MadridAges 18 years+ - NCT04607174Recruiting
Test knee muscle activation in people with nerve or movement disorders
This study checks how well your knee muscles “turn on” during guided, controlled knee movements. It may help researchers understand movement problems and improve testing or therapies for neuromotor (nerve/movement) disorders.
Milan, MIAges 18–70 - NCT04609709Recruiting
Physical therapy plus electrical dry needling for tension headaches
This trial tests whether specific physical therapy treatments—exercise, manual soft-tissue work, mobilization, and electrical dry needling/TENS—can reduce tension-type headaches. It may help if your headaches happen often and fit the trial’s “frequent” or “chronic” pattern.
Fort Wayne, IndianaAges 18–65 - NCT04610697Recruiting
Cognitive training for people in forensic mental health care
This trial studies whether a structured “cognitive remediation” program (training thinking skills) can help people receiving care on a forensic treatment unit. It may benefit those who want support improving attention, memory, or problem-solving as part of their treatment.
Ottawa, OntarioAges 18–55 - NCT04611009RecruitingPhase 2
Video training for writer’s cramp with attention and movement practice
This trial tests a video-guided program to improve hand control and awareness for people with writer’s cramp. It may help reduce crampy, involuntary hand movements by teaching safer, more coordinated practice.
Kiel, Schleswig-HolsteinAges 18–80 - NCT04613089Recruiting
Study of Batten disease progress and clinical changes over time
This trial tracks how Batten disease (NCL) affects the body and how symptoms change over time. If you have a confirmed genetic (molecular) diagnosis—especially CLN2 with Brineura treatment—it may help researchers understand disease patterns and care needs.
HamburgAges Any age - NCT04615065Recruiting
Biobank study collecting emergency data for very sick patients
This study collects health and sometimes blood sample information from people arriving at the emergency department with high-risk or serious conditions. The goal is to build a large emergency “biobank” to help researchers better understand and improve urgent care.
GroningenAges 18 years+ - NCT04616508Recruiting
Online arm movement training for people with Parkinson’s
This study uses online tasks to look at how people with Parkinson’s control reaching movements. You may benefit by contributing to research that could improve understanding and future treatments for movement problems.
Newark, DelawareAges 18–85 - NCT04620642Recruiting
Registry for adults treated with clot-busting or clot removal
This trial is a registry that collects information from adults who were hospitalized for an ischemic stroke and received either clot-busting medicine or a procedure to remove the clot. It may help doctors better understand stroke treatments and outcomes.
LyonAges 18 years+ - NCT04621357Recruiting
Testing how brain swelling affects recovery after brain bleeding
This study looks at brain swelling (“cerebral edema”) after a spontaneous brain bleed and how it relates to outcomes. It mainly involves people who can have early care and MRI scans, to better understand what affects recovery.
LilleAges 18 years+ - NCT04621279Recruiting
Cooling treatment study for babies with mild brain injury
This study compares different approaches to “cooling” treatment in newborns with mild hypoxic-ischemic encephalopathy (mild brain injury from not enough oxygen around birth). The goal is to see which approach works best and is safest for babies like yours.
Dallas, TexasAges 8 months+ - NCT04623593Recruiting
Study of cost and value of neck disc surgery
This study looks at how cost-effective (good value for the money) anterior neck disc surgery is for people with nerve or spinal cord symptoms. If you need this type of operation, it may help doctors better choose treatments and plan healthcare resources.
Maastricht, LimburgAges 18 years+ - NCT04623463Recruiting
Exercise and how it affects sleep apnea severity
This study looks at whether regular physical activity can make obstructive sleep apnea (OSA) less severe. It focuses on people who are not yet receiving OSA treatment and checks changes in severity over time.
GrenobleAges 18–80 - NCT04624295RecruitingPhase 4
Aspirin soon after certain bleeding stroke, after clot-busting therapy
This trial studies whether starting aspirin early is safe and helpful for people who, after clot-busting treatment for an ischemic stroke, develop a specific type of small brain bleeding called hemorrhagic infarction. You might benefit if your scan later shows this pattern of bleeding and you are not able to take blood-thinners or aspirin is safe for you.
HangzhouAges Any age - NCT04626167RecruitingEarly Phase 1
Testing a bladder transplant done with a kidney transplant
This early-phase study is testing a combined bladder and kidney transplant approach for people whose bladder problems damage the kidneys. The goal is to see if this treatment can improve bladder and kidney outcomes and be done safely.
Rochester, MinnesotaAges 1–60
Common questions
- How many brain & nervous system clinical trials are recruiting?
- Clin2 is tracking 12,425 recruiting neurology studies from the U.S. registry right now, out of 19,436 we cover in this area in total.
- What does “Brain & nervous system” cover here?
- Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We group each study into brain & nervous system based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a brain & nervous system trial near me?
- Use the search to filter brain & nervous system studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.