Neurology
Brain & nervous system clinical trials
Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We’re tracking 11,952 recruiting studies in this area right now.
By phase
- Not applicable9,355
- Phase 2761
- Phase 1558
- Phase 3514
- Phase 4339
- Phase 1/Phase 2300
- Phase 2/Phase 3125
Top conditions
- Stroke798
- Parkinson Disease395
- Alzheimer Disease338
- Multiple Sclerosis328
- Dementia226
- Epilepsy193
- Ischemic Stroke190
- Insomnia159
- Traumatic Brain Injury151
- Obstructive Sleep Apnea142
- Spinal Cord Injuries142
- Acute Ischemic Stroke138
- Sarcopenia134
- Mild Cognitive Impairment127
- Cerebral Palsy119
- Pain Management116
- Migraine107
- Fibromyalgia104
Leading sponsors
- Beijing Tiantan Hospital124
- Assistance Publique - Hôpitaux de Paris109
- Riphah International University105
- Mayo Clinic98
- VA Office of Research and Development92
- Xuanwu Hospital, Beijing89
- Hospices Civils de Lyon77
- Johns Hopkins University69
- University of Minnesota63
- Washington University School of Medicine63
Where studies are running
- California661
- Massachusetts305
- New York295
- Florida272
- Texas266
- Maryland248
- Alabama207
- Arizona206
- Illinois181
- Pennsylvania177
Recruiting studies11,952 total
- NCT07456722Recruiting
Heart health in spinal cord injury with autonomic dysreflexia
This study looks at how the heart is built and works in people with long-term spinal cord injury, especially those who have autonomic dysreflexia. It might help doctors understand heart risks and improve care.
NottwilAges 18 years+ - NCT07459660Enrolling by invitationPhase 2
Long-term study of ML-007C-MA for Alzheimer's psychosis
This trial tests a long-term treatment (ML-007C-MA) for people with Alzheimer's disease who have psychosis. It is for those who already completed an earlier study with the same drug and may benefit from continuing it. The goal is to see if ongoing treatment is helpful and safe.
Anaheim, CaliforniaAges 55–91 - NCT07455383RecruitingPhase 3
Testing ALKS 2680 for adults with narcolepsy type 1
This study tests a new medication, ALKS 2680, to see if it helps reduce daytime sleepiness and other symptoms in adults with narcolepsy type 1. It may offer a new treatment option for people with this condition.
Cullman, AlabamaAges 18–70 - NCT07453888RecruitingPhase 3
Nose spray for sudden vision loss from optic nerve damage
This trial tests a nose spray medication (cenegermin) for people who recently lost vision due to a specific type of optic nerve damage (NAION). The goal is to see if it can help restore sight when started within two weeks of vision loss.
Los Angeles, CaliforniaAges 50–80 - NCT07461220RecruitingPhase 1/Phase 2
Testing IRL757 for apathy in Parkinson's disease
This trial tests a new drug called IRL757 to see if it is safe and helps with apathy (loss of motivation or interest) in people with Parkinson's disease. You need to have at least moderate apathy and a caregiver who can come to visits with you.
PlevenAges 50–90 - NCT07461259Recruiting
Testing a new exoskeleton for walking after spinal cord injury
This trial tests a powered exoskeleton called TWIICE Rise to see if it is safe and possible for people with spinal cord injury to use it for walking. It may help if you have some movement or no movement in your legs but need help standing and walking with crutches.
Nottwil, Canton of LucerneAges 18–70 - NCT07457060RecruitingPhase 4
Polio vaccine study for 2-month-old infants
This study tests giving babies two different types of polio vaccines in a specific order to see which is safer and more effective. If your baby is about 2 months old and hasn't had any polio vaccine yet, they may be able to join.
Kawit, CaviteAges 2 months–3 months - NCT07455747Recruiting
Study of a new system for treating carotid artery disease
This study is testing a special system (ENROUTE Transcarotid Neuroprotection) used with a stent to treat narrowed carotid arteries, which can help prevent stroke. It looks at how well the system works in real medical settings.
St Louis, MissouriAges 18 years+ - NCT07455136Recruiting
Blood test for traumatic brain injury diagnosis and monitoring
This study is testing a new blood-based test to help doctors diagnose traumatic brain injury (TBI) and track recovery or complications. If you have had a head injury and a CT scan as part of your care, you may be able to join.
Sacramento, CaliforniaAges 18 years+ - NCT04073290RecruitingPhase 4
Rifaximin and lactulose to prevent confusion after TIPS
This trial studies whether taking rifaximin plus lactulose can prevent a brain problem called hepatic encephalopathy (confusion) after TIPS, a procedure to reduce pressure in the liver. It may help people who are having TIPS planned and are at risk of this complication.
LeuvenAges 18–80 - NCT05097001Recruiting
Personalized brain-stimulation program for dystonia using imaging
This study tests whether using brain imaging to guide stimulation settings can improve symptoms in people with long-term deep brain stimulation for dystonia. It will compare different stimulation approaches in a blinded, step-by-step crossover design to see which one helps more.
Würzburg, BavariaAges 18 years+ - NCT05340062Recruiting
Noninvasive brain-pressure check versus invasive test in children
This trial compares a noninvasive way to measure brain pressure to an invasive method in children. It may help reduce the need for painful or risky procedures while still getting useful measurements for care.
BolognaAges Up to 18 years - NCT05715710Recruiting
MRI and brain vein pattern study for memory and thinking problems
This study looks at whether certain deep brain veins seen on MRI are linked to thinking and memory problems in people with small-vessel brain disease. It compares brain scan findings with cognitive (thinking) testing to better understand what may drive cognitive dysfunction.
Zigong, SichuanAges 50–85 - NCT06374667Recruiting
Skull bone injection vs. IV for large stroke
This trial tests a new way to give medicine for a large stroke on one side of the brain. The medicine is injected into the skull bone instead of through a vein, and researchers want to see if it works better and is safe.
Wuhu, AnhuiAges 18–80 - NCT07456956Recruiting
Exercise comparison for muscle loss after stroke
This trial compares two types of leg exercise programs (high-intensity vs. moderate-intensity interval training) to see which better helps rebuild muscle strength and function in people who have had a stroke within the past 1 to 6 months.
Istanbul, AtaşehirAges 18–80 - NCT07458568Recruiting
ViBandz study for children with movement problems
This study tests a wearable device called ViBandz that gives gentle vibrations to help children with neurologic conditions move better. It is for children who are already scheduled to receive this type of vibration therapy as part of their regular care at Children's Mercy Hospital.
Kansas City, MissouriAges 6 months–17 years - NCT07455201Recruiting
CT scan for brain bleed removal surgery
This trial studies a new CT scan designed to help doctors guide a special minimally invasive surgery to remove a brain bleed. It's for patients who are already scheduled for this procedure at Mount Sinai West Hospital.
New York, New YorkAges 18 years+ - NCT07458815Recruiting
Vitamin D for stroke recovery after brain bleed
This trial tests whether vitamin D supplements can help people recover after a specific type of stroke (intracerebral hemorrhage). It is for adults who had a moderate-sized bleed in the upper part of the brain within the last 4 days and were otherwise independent before the stroke.
Hong KongAges 18–90 - NCT07454733Recruiting
Do videos of clinic meetings improve quality of life in ALS?
This study looks at whether watching videos of your clinic team meetings helps improve quality of life for people with ALS and their caregivers. You and your caregiver would both take part, and you'd need to be able to use the internet and email.
Scottsdale, ArizonaAges 18 years+ - NCT07462195RecruitingPhase 4
Dexmedetomidine for smoother recovery after thyroid surgery
This trial tests whether adding a medicine called dexmedetomidine during thyroid surgery helps you wake up more calmly and comfortably. It may reduce side effects like confusion or shakiness after anesthesia.
HanoiAges 18–65 - NCT07459478Recruiting
Tilt-table test for vasovagal fainting
This study looks at whether using a tilt-table (a special table that tilts you upright to trigger fainting) helps doctors better understand and treat fainting caused by vasovagal syncope. If you have this type of fainting, this study could help find better ways to manage it.
AmsterdamAges 18 years+ - NCT07460804Recruiting
Sit to stand study for chronic stroke survivors
This trial tests a specific exercise to help people who had a stroke more than 6 months ago improve their ability to stand up from a chair. It may help you if you have some trouble but can still do the movement with minimal or no help.
Cullowhee, North CarolinaAges 18 years+ - NCT07461896Recruiting
Nerve function study in Charcot-Marie-Tooth and related neuropathies
This study looks at how nerves work and their structure in people with Charcot-Marie-Tooth disease, CIDP, or anti-MAG neuropathy. It may help doctors better understand these conditions.
MilanAges 18 years+ - NCT07455162Recruiting
Gesture plus speech therapy for Cantonese speakers with aphasia
This study tests whether combining hand gestures with speaking helps Cantonese speakers who have trouble finding words after a stroke. If you have aphasia and can repeat single words, you may be able to join.
Hong KongAges 18 years+
Common questions
- How many brain & nervous system clinical trials are recruiting?
- Clin2 is tracking 11,952 recruiting neurology studies from the U.S. registry right now, out of 18,491 we cover in this area in total.
- What does “Brain & nervous system” cover here?
- Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We group each study into brain & nervous system based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a brain & nervous system trial near me?
- Use the search to filter brain & nervous system studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.