Neurology
Brain & nervous system clinical trials
Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We’re tracking 12,425 recruiting studies in this area right now.
By phase
- Not applicable9,762
- Phase 2784
- Phase 1574
- Phase 3535
- Phase 4342
- Phase 1/Phase 2305
- Phase 2/Phase 3123
Top conditions
- Stroke845
- Parkinson Disease426
- Multiple Sclerosis343
- Alzheimer Disease341
- Dementia226
- Ischemic Stroke200
- Epilepsy197
- Obstructive Sleep Apnea155
- Spinal Cord Injuries154
- Insomnia153
- Sarcopenia149
- Traumatic Brain Injury149
- Acute Ischemic Stroke139
- Cerebral Palsy131
- Mild Cognitive Impairment129
- Pain Management114
- Migraine112
- Amyotrophic Lateral Sclerosis108
Leading sponsors
- Beijing Tiantan Hospital133
- Riphah International University125
- Assistance Publique - Hôpitaux de Paris112
- Mayo Clinic99
- Xuanwu Hospital, Beijing94
- VA Office of Research and Development93
- Hospices Civils de Lyon79
- Johns Hopkins University70
- National Taiwan University Hospital70
- University of Minnesota64
Where studies are running
- California678
- Massachusetts300
- New York292
- Florida275
- Texas267
- Maryland245
- Arizona213
- Alabama211
- Illinois189
- Pennsylvania178
Recruiting studies12,423 total
- NCT04837105Recruiting
Game-based training to help children walk better with cerebral palsy
This study tests whether a serious video game can improve walking and movement in children with cerebral palsy. It may help your child practice safer, more effective walking skills through guided play.
Saint-Fargeau-Ponthierry, Île-de-France RegionAges 10–18 - NCT04837625Recruiting
Study of myasthenic crisis treatments for emergency breathing problems
This trial studies myasthenic crisis—an urgent, life-threatening worsening of myasthenia gravis that can affect breathing. It aims to better understand and treat people who need breathing support now, or may need it soon.
Shanghai, Shanghai MunicipalityAges 18 years+ - NCT04839887Recruiting
Quality of life after stroke in adults aged 18–65
This trial looks at what affects quality of life after an ischemic stroke (a type of stroke caused by a blocked blood vessel) in younger adults. You may be able to join if you can complete questionnaires about your recovery and daily life.
OlomoucAges 18–65 - NCT04842812RecruitingPhase 1
Personalized immune cell therapy for advanced solid tumors
This Phase 1 study tests engineered immune cells (TILs/CAR-TILs) made from your tumor to treat advanced solid cancers that have not responded to standard treatments. It may help your immune system better recognize and attack the cancer, but it is mainly focused on safety and early results.
GuangzhouAges 18–85 - NCT04844060Recruiting
Study collecting spinal fluid from patients needing a lumbar puncture
This study collects cerebrospinal fluid (the fluid around the brain and spinal cord) during a lumbar puncture. It aims to improve how doctors use this information for accurate diagnosis in patients who need the procedure.
StrasbourgAges Any age - NCT04847284Recruiting
Radiation during brain tumor surgery for brain metastases
This trial tests giving targeted radiation while surgeons are operating to treat brain metastases. It may help control the cancer locally at the time of surgery, especially for certain single lesions.
BarcelonaAges 18 years+ - NCT04847752Recruiting
Predicting outcomes after stroke from artery plaque
This study looks at factors that can help predict recovery and risk after an ischemic stroke caused by plaque buildup in a major artery. It may help doctors better forecast prognosis and tailor follow-up care for people like you.
WuhanAges Up to 80 years - NCT04848077Recruiting
Smartphone exercise program for early Parkinson’s patients
This trial tests whether a motivating phone-based exercise plan can help people with early-stage Parkinson’s move more safely and consistently. You may qualify if you can walk on your own, understand Dutch, and are fairly inactive right now.
Nijmegen, GelderlandAges 18 years+ - NCT04849806Recruiting
Testing whether heart nerve signals predict COPD symptoms
This study looks at “sympathetic nerve activity” (signals from the nervous system that affect the heart) in adults with chronic obstructive pulmonary disease (COPD). The goal is to see whether these measurements can help predict what happens to people with COPD.
AachenAges 18 years+ - NCT04850053Recruiting
Using brain-related “seeds” to help diagnose Alzheimer’s disease
This study looks for specific markers (“seeds”) that may help doctors diagnose Alzheimer’s disease and distinguish it from other memory or thinking conditions. If you are in the right age range and can complete memory testing and provide a sample, you may help validate a diagnostic approach.
Beijing, Beijing MunicipalityAges 55–75 - NCT04851886Recruiting
Vision tool to guide robot therapy for stroke arm posture
This trial tests a vision-based system that detects your arm and posture during robot-assisted upper-arm therapy after a prior stroke. It may help the robot guide treatment more safely and accurately based on your movements and positioning.
Charlestown, MassachusettsAges 18–80 - NCT04851678Recruiting
Study how stress affects adults with Tourette syndrome
This study follows adults with Tourette syndrome over time to better understand how stressors affect symptoms and daily life. It may help researchers learn what factors make symptoms better or worse and improve future care.
Nashville, TennesseeAges 18 years+ - NCT04852354Recruiting
Donate brain/spinal tumor tissue for drug testing
This study collects leftover brain or spinal tumor tissue during neurosurgery (or from autopsies) so researchers can test drugs and measure how they work. It may help future treatments by improving drug screening using real patient tissue.
New York, New YorkAges Any age - NCT04855396Recruiting
Study of blood markers during hyperbaric oxygen brain injury care
This trial looks at blood “biomarkers,” or lab measurements, while people receive hyperbaric oxygen treatment for brain injury as part of the main HOBIT study. It may help researchers understand who benefits and why by improving how treatment responses are tracked.
San Diego, CaliforniaAges 16–65 - NCT04855630Recruiting
Sleep and mild exercise program for thinking and memory support
This study tests whether combining better sleep routines with mild exercise can help with memory, concentration, and thinking speed. To do that, you would wear special devices and complete quick at-home and in-person assessments and a small finger-prick blood test.
Miami, FloridaAges 45–80 - NCT04855825Recruiting
Wearable robotic exoskeleton to improve walking and thinking in MS
This study tests a wearable robotic exoskeleton to help people with multiple sclerosis walk better and improve thinking/problem-solving. You would use the device during supervised sessions and take brief thinking and movement checks to see if it’s safe and helpful for you.
West Orange, New JerseyAges 18–75 - NCT04856059Recruiting
MRI study for early heart changes in Fabry disease
This study looks at early structural and tissue changes in the heart using a special type of MRI scan in adults with Fabry disease. It may help doctors understand changes earlier and better track heart involvement over time.
Toronto, OntarioAges 18 years+ - NCT04861051RecruitingPhase 1
Study ketamine effects on brain sensations in adults
This Phase 1 study tests how ketamine changes “dissociative” experiences—feelings of being disconnected from thoughts or surroundings—in adults. You may be helping researchers better understand ketamine’s effects, which could guide safer future uses.
Palo Alto, CaliforniaAges 18 years+ - NCT04859335Recruiting
Tracking balance and inner-ear function after Gamma Knife for schwannoma
This study looks at how balance and inner-ear (vestibular) function change after Gamma Knife radiosurgery for vestibular schwannoma. It may help doctors understand what to expect during recovery and how well these functions improve.
ToulouseAges 18–65 - NCT04860141RecruitingPhase 4
Gabapentin before wisdom tooth removal to reduce pain
This trial tests whether taking gabapentin before extracting a wisdom tooth helps with pain and comfort after the procedure. It may help people who need a third-molar removal, if they meet the safety and health requirements.
Loma Linda, CaliforniaAges 18–59 - NCT04862507Recruiting
Thrombectomy treatment for severe stroke with low ASPECTS
This trial studies an approach for removing a blockage using thrombectomy in people with an acute ischemic stroke that shows a low ASPECTS score. It may help restore blood flow in strokes that have significant early changes on brain imaging.
BerlinAges 18 years+ - NCT04863612Recruiting
SBRT for spinal tumors with possible spinal cord pressure
This study looks at treating spinal metastases (spread to the spine from a solid cancer) using SBRT, a focused type of radiation. It aims to control tumor growth and relieve or prevent spinal cord compression, sometimes alongside surgery.
Leuven, Vlaams BrabantAges 18–99 - NCT04867187Recruiting
Brain stimulation plus mirror therapy for nerve pain
This trial tests whether a noninvasive brain stimulation treatment (repeated TMS) combined with mirror therapy can reduce nerve pain. It may help people whose nerve pain has lasted for months and hasn’t improved enough with usual medicines.
BronAges 18–85 - NCT04869059Recruiting
tDCS for mild brain injury memory word finding
This trial tests whether a noninvasive brain stimulation treatment (tDCS) can improve word-retrieval problems after a mild or moderate concussion-like brain injury. It may help if testing shows trouble finding the right words when speaking.
Dallas, TexasAges 18–75
Common questions
- How many brain & nervous system clinical trials are recruiting?
- Clin2 is tracking 12,425 recruiting neurology studies from the U.S. registry right now, out of 19,436 we cover in this area in total.
- What does “Brain & nervous system” cover here?
- Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We group each study into brain & nervous system based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a brain & nervous system trial near me?
- Use the search to filter brain & nervous system studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.