Neurology
Brain & nervous system clinical trials
Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We’re tracking 11,952 recruiting studies in this area right now.
By phase
- Not applicable9,355
- Phase 2761
- Phase 1558
- Phase 3514
- Phase 4339
- Phase 1/Phase 2300
- Phase 2/Phase 3125
Top conditions
- Stroke798
- Parkinson Disease395
- Alzheimer Disease338
- Multiple Sclerosis328
- Dementia226
- Epilepsy193
- Ischemic Stroke190
- Insomnia159
- Traumatic Brain Injury151
- Obstructive Sleep Apnea142
- Spinal Cord Injuries142
- Acute Ischemic Stroke138
- Sarcopenia134
- Mild Cognitive Impairment127
- Cerebral Palsy119
- Pain Management116
- Migraine107
- Fibromyalgia104
Leading sponsors
- Beijing Tiantan Hospital124
- Assistance Publique - Hôpitaux de Paris109
- Riphah International University105
- Mayo Clinic98
- VA Office of Research and Development92
- Xuanwu Hospital, Beijing89
- Hospices Civils de Lyon77
- Johns Hopkins University69
- University of Minnesota63
- Washington University School of Medicine63
Where studies are running
- California661
- Massachusetts305
- New York295
- Florida272
- Texas266
- Maryland248
- Alabama207
- Arizona206
- Illinois181
- Pennsylvania177
Recruiting studies11,952 total
- NCT07429240RecruitingPhase 1/Phase 2
Gene editing trial for Duchenne muscular dystrophy (ages 2-7)
This trial tests a new gene editing treatment called PBGENE-DMD for boys with Duchenne muscular dystrophy (DMD) whose genetic mutation falls within a specific range of the dystrophin gene (exons 45-55). The goal is to see if it is safe and can help improve muscle function.
Little Rock, ArkansasAges 2–7 - NCT07430917RecruitingPhase 2
Testing J147 for recent stroke from blocked artery
This trial tests a new drug, J147, for people who recently had a stroke caused by a blocked artery and have already had a procedure to reopen that artery. It aims to see if the drug can improve recovery.
Long Beach, CaliforniaAges 18–90 - NCT07430878Enrolling by invitation
Sleep tracking study for insomnia patterns
This study uses your Withings smartwatch or sleep monitor to track sleep patterns over time. It looks for signs of insomnia and how your sleep changes from night to night.
Issy-les-MoulineauxAges 18 years+ - NCT07430956RecruitingPhase 3
Stroke prevention in atrial fibrillation without standard blood thinners
This trial tests a new medication to prevent strokes and blood clots in people with atrial fibrillation (an irregular heartbeat) who cannot safely take standard blood thinners. The drug works by blocking a different clotting factor, which may lower bleeding risks.
Dothan, AlabamaAges 18 years+ - NCT07432958RecruitingPhase 2
Study of AP-472 with levodopa for Parkinson's motor fluctuations
This trial tests an experimental drug called AP-472, taken alongside your regular Parkinson's medications, to see if it can reduce the amount of "OFF" time you experience each day when symptoms return between doses of levodopa.
Little Rock, ArkansasAges 30–80 - NCT07428616RecruitingPhase 2
Study of Zanzalintinib for recurring meningioma
This trial tests a drug called Zanzalintinib for people with meningioma that has come back or grown despite past treatments. It aims to see if the drug can stop or slow tumor growth.
Birmingham, AlabamaAges 18 years+ - NCT07433946Recruiting
Liquid nutrition to prevent weight loss in IBD
This study tests whether adding a special liquid nutrition drink (partial enteral nutrition) to your regular diet can help prevent weight loss and muscle loss in people with Crohn's disease or ulcerative colitis who are at risk of malnutrition.
Rozzano, MilanoAges 18–65 - NCT06809842Recruiting
Nerve blocks for pain after knee surgery
This study compares two nerve blocks—one to a muscle nerve and one to a skin nerve—to see which works better for pain after knee surgery. If you're having knee surgery, these blocks could help you recover with less pain and fewer side effects.
Kafr ash Shaykh, KafrelsheikhAges 18 years+ - NCT01372800Recruiting
Study blood adiponectin levels and stroke/heart risk
This study measures a blood marker called adiponectin and looks at how it relates to heart and stroke (cardiovascular and cerebrovascular) problems over time. It may help doctors understand who is at higher risk, especially in Chinese participants.
Xi'an, ShaanxiAges 18–85 - NCT03781128RecruitingPhase 2
LSD for cluster headaches in a clinical study
This Phase 2 study tests whether a supervised dose of LSD (or a placebo) can reduce cluster headache attacks. It’s for people whose cluster headaches respond to oxygen, and who can safely pause certain medications and substances around the dosing day.
BaselAges 25–75 - NCT07428447Recruiting
Skin test to see if essential tremor may progress to Parkinson's
This study uses a small skin sample to look for a protein linked to Parkinson's disease. It aims to help people with essential tremor understand their risk of developing Parkinson's, which could guide future care.
Scottsdale, ArizonaAges 50–85 - NCT07429305Recruiting
Nerve stimulation and standing for spinal cord injury
This trial tests whether combining a nerve stimulation therapy with standing exercises can improve bladder and bowel function after a spinal cord injury. It may help people who have nerve-related bladder problems.
Vancouver, British ColumbiaAges 19 years+ - NCT07433257Recruiting
Steroid injection for carpal tunnel with diabetes
This study tests if a steroid injection in the wrist helps people with carpal tunnel syndrome, comparing results between those with and without type 2 diabetes. If you have mild to moderate carpal tunnel and either well-controlled diabetes or no diabetes, you may be able to join.
Istanbul, IstanbulAges 18–75 - NCT07429422Recruiting
Precise Radiation for Spine Tumors
This trial is testing a very precise radiation technique called SBRT for tumors that have spread to the spine. It aims to see if this approach can treat the tumor effectively while reducing side effects.
LjubljanaAges 18 years+ - NCT07429578Recruiting
Brain stimulation for anxiety and insomnia
This study tests whether a gentle, non-invasive brain stimulation technique (tACS) can help people who have both generalized anxiety and long-term sleep problems. It aims to see if this treatment can reduce anxiety and improve sleep.
São Paulo, São PauloAges 18–65 - NCT07430774Recruiting
Depression, emotions, and heart rate in teens
This study looks at how your relationship with your parent and your emotions affect your heart rate and depression. You will wear a Fitbit for a week and answer questionnaires about your feelings and daily habits.
Dallas, TexasAges 12–18 - NCT07427589Recruiting
New Heart Tests in Sleep Apnea
This study looks at how sleep apnea affects your heart and blood vessels over time. It uses a sleep study and heart tests to see if certain measurements can predict heart health changes.
AntwerpAges 18 years+ - NCT07430761Recruiting
Stigma and tremor suppression in essential tremor
This study looks at how stigma (feeling embarrassed or judged) affects people with essential tremor who are planning to have a focused ultrasound procedure to reduce their tremor. It aims to understand feelings before and after treatment.
Dallas, TexasAges 18 years+ - NCT07430345RecruitingPhase 1/Phase 2
Buprenorphine for pain in older adults with broken bones
This trial tests a low-dose pain medicine called buprenorphine for people 65 and older who come to the emergency room with a broken bone. It aims to find a safe way to manage pain in older adults.
Camden, New JerseyAges 65 years+ - NCT07432789Recruiting
Testing a motion app for children with cerebral palsy
This study tests a smartphone app that measures how children with cerebral palsy move. It aims to see if the app can accurately track motor abilities, which could help doctors and families monitor progress more easily.
DijonAges 6–18 - NCT07427537Recruiting
Studying nerve damage from chemotherapy in colorectal and lung cancer patients
This study looks for small molecules in the blood that might predict nerve damage caused by certain chemotherapies. If you have colorectal or lung cancer and are starting a specific chemo plan, this trial could help researchers understand why some people get nerve problems and others don't.
Clermont-FerrandAges 18 years+ - NCT07432074Enrolling by invitation
Acupressure and massage after cesarean section
This study tests whether acupressure (gentle pressure on specific points) or massage can help women recover after a planned cesarean. It aims to reduce pain and improve comfort without using extra medicine.
IstanbulAges 18–45 - NCT07426991Recruiting
Multiple sclerosis, thinking, sleep, and tiredness study
This study looks at how multiple sclerosis (MS) affects your thinking, sleep, and tiredness. It compares people with MS who have at least mild fatigue to people without MS who also have sleep problems, to understand these issues better.
DüsseldorfAges 18–79 - NCT07425652Recruiting
Physiotherapy methods for fibromyalgia pain
This study tests different physiotherapy techniques to help women with fibromyalgia manage pain and improve daily function. It compares several hands-on therapies to find the most effective approach.
AnkaraAges 18–65
Common questions
- How many brain & nervous system clinical trials are recruiting?
- Clin2 is tracking 11,952 recruiting neurology studies from the U.S. registry right now, out of 18,491 we cover in this area in total.
- What does “Brain & nervous system” cover here?
- Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We group each study into brain & nervous system based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a brain & nervous system trial near me?
- Use the search to filter brain & nervous system studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.