Neurology
Brain & nervous system clinical trials
Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We’re tracking 11,952 recruiting studies in this area right now.
By phase
- Not applicable9,355
- Phase 2761
- Phase 1558
- Phase 3514
- Phase 4339
- Phase 1/Phase 2300
- Phase 2/Phase 3125
Top conditions
- Stroke798
- Parkinson Disease395
- Alzheimer Disease338
- Multiple Sclerosis328
- Dementia226
- Epilepsy193
- Ischemic Stroke190
- Insomnia159
- Traumatic Brain Injury151
- Obstructive Sleep Apnea142
- Spinal Cord Injuries142
- Acute Ischemic Stroke138
- Sarcopenia134
- Mild Cognitive Impairment127
- Cerebral Palsy119
- Pain Management116
- Migraine107
- Fibromyalgia104
Leading sponsors
- Beijing Tiantan Hospital124
- Assistance Publique - Hôpitaux de Paris109
- Riphah International University105
- Mayo Clinic98
- VA Office of Research and Development92
- Xuanwu Hospital, Beijing89
- Hospices Civils de Lyon77
- Johns Hopkins University69
- University of Minnesota63
- Washington University School of Medicine63
Where studies are running
- California661
- Massachusetts305
- New York295
- Florida272
- Texas266
- Maryland248
- Alabama207
- Arizona206
- Illinois181
- Pennsylvania177
Recruiting studies11,952 total
- NCT05378490Recruiting
Study of stroke types and thrombolysis treatment
This study includes people who have had certain kinds of sudden brain blood-flow problems (like an ischemic stroke, bleeding in the brain, or a brief warning episode) or conditions that look similar. It looks at how treatment such as clot-busting medicine (thrombolysis) fits for these situations.
LørenskogAges 18 years+ - NCT06072105Recruiting
Medical decisions in multiple system atrophy: a study in Austria
This study looks at how medical decisions are made for people with multiple system atrophy (MSA). It includes both people with MSA and their unpaid caregivers who live in Austria and speak German. Participants and caregivers will share their experiences through online interviews to help improve future care.
Innsbruck, AustriaAges 30 years+ - NCT06412055Recruiting
Adjustable stiffness ankle-foot orthosis study
This study is testing a special ankle-foot orthosis (AFO) that can be adjusted to be more or less stiff. It's for people with foot drop or ankle weakness who already use or need an AFO, and can walk at least a short distance.
AmsterdamAges 18 years+ - NCT06550284Recruiting
Nerve sensitivity in carpal tunnel syndrome
This study tests how small nerve fibers work in people with carpal tunnel syndrome. It uses simple sensory tests to understand nerve function, which may help guide treatment.
San Antonio, TexasAges 18–65 - NCT06663969Recruiting
Temporal Interference Stimulation for Epilepsy
This trial tests a new, gentle way to stimulate specific brain areas using a special electrical signal. It aims to see if this can help people with epilepsy that hasn't improved with medication.
Beijing, Beijing MunicipalityAges 14–65 - NCT04066465Recruiting
Testing how proton therapy affects thinking in young people
This study looks at how proton radiation therapy may affect thinking, learning, and brain function in children and teens with a primary brain tumor. It uses repeated short brain/learning tests to track possible changes over time.
Dresden, SaxonyAges 8–18 - NCT05850247RecruitingPhase 2
Study brain inflammation in carotid artery narrowing after stroke or TIA
This Phase 2 study looks at a protein called ficolin-2 and whether it relates to brain inflammation after a short stroke-like event or eye blood vessel blockage caused by narrowed carotid arteries. If you recently had symptoms from the carotid artery and meet imaging and health criteria, you may be offered study-related assessments to better understand the cause and help future treatment decisions.
BronAges 18 years+ - NCT06810219Recruiting
Brain-computer interface study for ALS communication
This study tests a brain-computer interface (BCI) that uses augmented reality glasses to help people with late-stage ALS communicate. You wear a headset that reads your brain signals and lets you select words or phrases on a screen, giving you a new way to talk to others.
Santa Barbara, CaliforniaAges 18 years+ - NCT05119842Recruiting
Implant study for permanent voice weakness from vocal cord closure
This study tests a voice implant device in people with permanent vocal cord weakness (UVFP) who have trouble closing their vocal cords. It aims to improve voice strength and reduce voice-related burden, while checking safety over the study period.
Phoenix, ArizonaAges 18–80 - NCT03344276Recruiting
Testing thinking and memory after carotid artery treatment
This study checks how a carotid artery procedure affects thinking and memory. You may be able to join if you’re an adult with significant carotid artery narrowing seen on ultrasound, and you can safely do follow-up MRI scans.
San Diego, CaliforniaAges 18 years+ - NCT04759443Recruiting
Skin testing to detect small-fiber nerve damage
This study looks for small-fiber neuropathy (nerve damage that can affect pain and sensation) by examining skin properties. It may help researchers find easier ways to detect this condition using skin-based testing.
Boston, MassachusettsAges 18 years+ - NCT05416385Recruiting
Stress echo scan with special contrast to study carotid plaque
This study uses a heart stress ultrasound test, plus a contrast dye, to look for new blood vessel growth inside carotid plaque (the buildup in neck arteries). It may help doctors better judge the risk of stroke and determine which people need closer care.
Calgary, AlbertaAges 18 years+ - NCT05520268Recruiting
Music therapy plus digital rehab for dementia symptoms
This study tests whether music therapy and a digital music program can improve symptoms and daily functioning in people living with dementia. It may help support memory, mood, or communication by using music-based activities.
HelsinkiAges 60 years+ - NCT06120049RecruitingPhase 2/Phase 3
Comparing new PET scans for Parkinson's, MSA, Lewy body dementia, and Alzheimer's
This study tests if a new radioactive tracer called [18F]-MFBG can help doctors better distinguish between Parkinson's disease, multiple system atrophy (MSA), dementia with Lewy bodies, and Alzheimer's disease. It compares the new scan with two standard scans to see which is most accurate.
Ghent, GentAges 18–85 - NCT06813586Recruiting
Study of cerebral palsy cases in Italy
This study observes children with cerebral palsy to better understand how common it is in Italy. It may help improve care and resources for people with CP.
Brindisi, ApuliaAges 4–18 - NCT06286189RecruitingPhase 1/Phase 2
Testing trazodone for sleep apnea
This trial tests whether the medication trazodone can help people with moderate to severe obstructive sleep apnea (OSA). If you have OSA and are not taking certain medications or have other sleep disorders, you may be able to join.
Boston, MassachusettsAges 21–70 - NCT06343688Recruiting
How ankle braces affect motor skills in CP
This study tests how wearing special ankle braces (called DAFOs) right away affects movement and balance in children with spastic diplegic cerebral palsy. It aims to see if the braces make it easier to walk and stand.
BoluAges 4–15 - NCT06568107Recruiting
Sensory and environment trial for dementia with repeated vocalizations
This study tests whether a calming environment and gentle sensory activities (like soothing sounds or textures) can help nursing home residents with dementia who make repeated sounds or cries. The goal is to see if these interventions can reduce those vocalizations and improve well-being.
Philadelphia, PennsylvaniaAges 50 years+ - NCT07430150Recruiting
Long-term effects of oxygen therapy on thinking after brain injury
This study checks if hyperbaric oxygen therapy (breathing pure oxygen in a special chamber) has lasting benefits for thinking skills in people who have had a traumatic brain injury.
ZrifinAges 18 years+ - NCT07429448RecruitingPhase 1
Numbing medicine for pain after appendix removal
This trial tests whether numbing medicine (bupivacaine) placed into the belly during an open appendix removal helps reduce pain after surgery, compared to a placebo (a shot with no medicine).
Lahore, Punjab ProvinceAges 20–60 - NCT07426965Recruiting
Ultrasound findings and pain in stroke patients with shoulder pain
This study uses ultrasound to look at the shoulder on the side affected by stroke and see how it relates to pain. It may help understand why shoulder pain happens after a stroke.
AnkaraAges 18–75 - NCT06718933RecruitingPhase 1/Phase 2
Study of a drug combination for breast cancer that spread to the brain
This trial tests whether a combination of three drugs (SHR-A1811, pyrotinib, and bevacizumab) can help people with advanced breast cancer that has spread to the brain. It aims to shrink brain tumors and stop them from growing.
Shanghai, Shanghai MunicipalityAges 18 years+ - NCT07430956RecruitingPhase 3
Stroke prevention in atrial fibrillation without standard blood thinners
This trial tests a new medication to prevent strokes and blood clots in people with atrial fibrillation (an irregular heartbeat) who cannot safely take standard blood thinners. The drug works by blocking a different clotting factor, which may lower bleeding risks.
Dothan, AlabamaAges 18 years+ - NCT07430878Enrolling by invitation
Sleep tracking study for insomnia patterns
This study uses your Withings smartwatch or sleep monitor to track sleep patterns over time. It looks for signs of insomnia and how your sleep changes from night to night.
Issy-les-MoulineauxAges 18 years+
Common questions
- How many brain & nervous system clinical trials are recruiting?
- Clin2 is tracking 11,952 recruiting neurology studies from the U.S. registry right now, out of 18,491 we cover in this area in total.
- What does “Brain & nervous system” cover here?
- Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We group each study into brain & nervous system based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a brain & nervous system trial near me?
- Use the search to filter brain & nervous system studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.