Neurology
Brain & nervous system clinical trials
Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We’re tracking 11,952 recruiting studies in this area right now.
By phase
- Not applicable9,355
- Phase 2761
- Phase 1558
- Phase 3514
- Phase 4339
- Phase 1/Phase 2300
- Phase 2/Phase 3125
Top conditions
- Stroke798
- Parkinson Disease395
- Alzheimer Disease338
- Multiple Sclerosis328
- Dementia226
- Epilepsy193
- Ischemic Stroke190
- Insomnia159
- Traumatic Brain Injury151
- Obstructive Sleep Apnea142
- Spinal Cord Injuries142
- Acute Ischemic Stroke138
- Sarcopenia134
- Mild Cognitive Impairment127
- Cerebral Palsy119
- Pain Management116
- Migraine107
- Fibromyalgia104
Leading sponsors
- Beijing Tiantan Hospital124
- Assistance Publique - Hôpitaux de Paris109
- Riphah International University105
- Mayo Clinic98
- VA Office of Research and Development92
- Xuanwu Hospital, Beijing89
- Hospices Civils de Lyon77
- Johns Hopkins University69
- University of Minnesota63
- Washington University School of Medicine63
Where studies are running
- California661
- Massachusetts305
- New York295
- Florida272
- Texas266
- Maryland248
- Alabama207
- Arizona206
- Illinois181
- Pennsylvania177
Recruiting studies11,952 total
- NCT04399200Recruiting
Study apnea after stroke to prevent new heart events
This trial looks at sleep apnea (breathing pauses during sleep) in people soon after a first stroke or a TIA, to see if it can be linked to new cardiovascular (heart/blood vessel) events. It also aims to make sure you can safely follow the study and rehabilitation plan.
GrenobleAges 18–85 - NCT04735627Recruiting
Real-time monitoring of levodopa levels in Parkinson’s
This study checks whether measuring levodopa (a Parkinson medicine) in real time can help better understand Parkinson medication effects. You may be asked to wear/perform study monitoring while taking your usual carbidopa/levodopa tablets.
San Diego, CaliforniaAges 40–85 - NCT07421960Recruiting
Periodontitis and sleep quality study
This study looks at how gum disease (periodontitis) might be related to sleep quality. It compares people with healthy gums to those with gum disease.
Istanbul, IstanbulAges 18–65 - NCT07417046Recruiting
Fluoxetine and eye patching for lazy eye treatment
This study tests whether a combination of a medicine (fluoxetine) and eye patching can improve vision in people with lazy eye (amblyopia). It uses special eye scans and brain wave tests to see how well the treatment works for different ages.
Minya, Minya GovernorateAges 10 years+ - NCT07416890RecruitingPhase 2
Study of thiotepa, pirtobrutinib, and sintilimab for CNS lymphoma
This trial tests a combination of three drugs for people with central nervous system (CNS) lymphoma that has come back or not responded to treatment, or for those who cannot take standard chemotherapy. The goal is to see if this new combination is safe and effective.
Hangzhou, ZhejiangAges 18–80 - NCT07421453Recruiting
Better recovery plan for draining brain blood clots
This trial is testing a new, step-by-step care plan (called an enhanced recovery pathway) for people who need a small hole drilled in their skull to drain a slow-growing blood clot (chronic subdural hematoma). The goal is to see if this organized approach helps patients recover faster and feel better.
LeuvenAges 18 years+ - NCT07424508Enrolling by invitation
Adaptive brain stimulation for Parkinson's movement symptoms
This trial tests a new type of deep brain stimulation that adapts to your movements to improve walking, balance, and tremors. It is for people with Parkinson's disease who have had symptoms for at least 3 years, are 21 to 75 years old, and already have a special study brain-stimulation device implanted.
San Francisco, CaliforniaAges 21–75 - NCT07420153Recruiting
Arm cuff treatment before surgery to prevent confusion
This study tests whether using a blood pressure cuff on the arm before surgery (called remote ischemic preconditioning) can help prevent confusion (delirium) after surgery. It is for older adults having planned non-cardiac surgery who are at risk for delirium.
Hamburg, Free and Hanseatic City of HamburgAges 50 years+ - NCT07417137Recruiting
Long-term study of Angelman syndrome
This study follows people with Angelman syndrome over time to learn more about the condition. It does not test any new treatments, but you need a parent or caregiver to come with you to all visits.
Lexington, MassachusettsAges 1 year+ - NCT07423923Enrolling by invitationEarly Phase 1
Memory and navigation study in healthy adults
This study uses brain scans (fMRI or iEEG) to understand how healthy people remember locations and navigate spaces. You may be eligible if you are a healthy adult aged 18–40 and meet the screening criteria.
Tucson, ArizonaAges 18–40 - NCT07423026Recruiting
Remote study using technology to track DMD in young boys
This study uses remote technology, like apps or wearable devices, to monitor motor skills and development in boys with Duchenne muscular dystrophy (DMD). It aims to find better ways to measure how the disease progresses over time without requiring frequent clinic visits.
OxfordAges 1–3 - NCT07424846RecruitingPhase 2/Phase 3
Xylitol gum to prevent gum disease and early birth
This trial tests if chewing xylitol gum during pregnancy can reduce gum disease and preterm birth. You would chew gum after meals and attend dental visits and follow-ups.
LilongweAges Any age - NCT07417085Recruiting
Study of gut bacteria in children with brain tumors
This study looks at how gut bacteria (the microbiome) may differ in children with brain tumors. Researchers will collect samples before and after surgery to understand the connection between gut health and brain tumors.
Florence, FirenzeAges 3–18 - NCT07419087Recruiting
French trunk impairment scale adaptation and validation study
This study aims to adapt and validate a French version of the Trunk Impairment Scale, a tool that measures how well stroke survivors can control their trunk (core body) movements. Participating will help researchers improve stroke recovery assessments.
Ploemeur, Please Choose...Ages 18–85 - NCT07423988Recruiting
Sleep changes at high altitude for Pic du Midi staff
This study looks at how sleep quality changes when you work overnight at high altitude (2877m) at the Pic du Midi observatory, compared to sleeping at home. It helps understand the effects of high-altitude work on rest.
Toulouse, OuiAges 18–65 - NCT07424976Enrolling by invitation
Early brain injury detection after infant heart surgery
This study looks for early signs of brain injury in infants after heart surgery that uses a heart-lung machine. It aims to improve monitoring and care for babies with congenital heart disease.
LjubljanaAges 1 week–1 year - NCT07418775Recruiting
Meningioma Study: Genes, Health & Life
This study looks at how your tumor's genes, personal health habits, and other factors affect your long-term health after a meningioma diagnosis. You'll be asked to complete surveys about your health and experiences—no new treatments or procedures are involved.
San Francisco, CaliforniaAges 18 years+ - NCT07417280Recruiting
Focused ultrasound for neurological disorders
This trial tests a gentle ultrasound treatment (LIFUS) for people with various brain conditions like epilepsy, tumours, or movement disorders. It aims to see if this non-invasive approach can help where other treatments are being used.
Toronto, OntarioAges 18–85 - NCT07424924Recruiting
Walking, activity, and sleep study for Parkinson's
This study looks at how walking, daily activity, and sleep are connected in Parkinson's disease. It compares people with Parkinson's to healthy volunteers to understand these links better.
IstanbulAges 40–75 - NCT07425106Enrolling by invitation
Comparing a low-cost eye scanner for Alzheimer's research
This study uses a special, low-cost eye scanner to look at the back of the eye (retina) in people with early Alzheimer's or mild memory problems. It aims to find changes that might help with early detection.
Durham, North CarolinaAges 18–85 - NCT07425457Recruiting
Cold nerve treatment before knee replacement surgery
This trial tests a cold therapy on nerves before knee replacement to reduce pain. It may help you recover with less discomfort after surgery.
AthensAges 18 years+ - NCT07418008Recruiting
Thinking and memory study for people with liver cirrhosis
This study is creating a new test to measure thinking and memory problems in people with liver cirrhosis. It may help doctors find these problems earlier.
Ambāla, HaryanaAges 18–75 - NCT07420400Recruiting
Detecting heart shunts without needles
This trial uses a specialized ultrasound test (TEE with bubble study) to find a small opening in the heart called a PFO. It may help people who need this test to check for causes of certain health problems.
La Jolla, CaliforniaAges 18 years+ - NCT07423377Recruiting
Vibration device for fibromyalgia pain
This trial tests if a device that delivers small vibrations to your ear can help reduce pain from fibromyalgia. You'll use the device as directed and answer online questions about your pain before and after.
New York, New YorkAges 18 years+
Common questions
- How many brain & nervous system clinical trials are recruiting?
- Clin2 is tracking 11,952 recruiting neurology studies from the U.S. registry right now, out of 18,491 we cover in this area in total.
- What does “Brain & nervous system” cover here?
- Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We group each study into brain & nervous system based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a brain & nervous system trial near me?
- Use the search to filter brain & nervous system studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.