Neurology
Brain & nervous system clinical trials
Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We’re tracking 12,425 recruiting studies in this area right now.
By phase
- Not applicable9,762
- Phase 2784
- Phase 1574
- Phase 3535
- Phase 4342
- Phase 1/Phase 2305
- Phase 2/Phase 3123
Top conditions
- Stroke845
- Parkinson Disease426
- Multiple Sclerosis343
- Alzheimer Disease341
- Dementia226
- Ischemic Stroke200
- Epilepsy197
- Obstructive Sleep Apnea155
- Spinal Cord Injuries154
- Insomnia153
- Sarcopenia149
- Traumatic Brain Injury149
- Acute Ischemic Stroke139
- Cerebral Palsy131
- Mild Cognitive Impairment129
- Pain Management114
- Migraine112
- Amyotrophic Lateral Sclerosis108
Leading sponsors
- Beijing Tiantan Hospital133
- Riphah International University125
- Assistance Publique - Hôpitaux de Paris112
- Mayo Clinic99
- Xuanwu Hospital, Beijing94
- VA Office of Research and Development93
- Hospices Civils de Lyon79
- Johns Hopkins University70
- National Taiwan University Hospital70
- University of Minnesota64
Where studies are running
- California678
- Massachusetts300
- New York292
- Florida275
- Texas267
- Maryland245
- Arizona213
- Alabama211
- Illinois189
- Pennsylvania178
Recruiting studies12,423 total
- NCT04988009Recruiting
Telemedicine care experience survey for brain tumor patients
This trial asks brain tumor patients and caregivers to share what they think about the quality of care they receive through telemedicine. Your feedback may help improve how neuro-oncology visits are done by video in the future.
Houston, TexasAges 18 years+ - NCT04989790Recruiting
Early mobility program for critically ill children in the PICU
This trial tests whether a structured “early mobility” activity plan (“PICU Up!”) helps children who are on a breathing machine recover or feel better while in the pediatric ICU. It aims to see if starting safe movement earlier makes a difference for critically ill kids.
Madera, CaliforniaAges Up to 18 years - NCT04990713Recruiting
Compare two pain-blocking methods during lung surgery
This study tests two different ways of numbing the chest to reduce pain during video-assisted lung surgery (VATS). It may help some people have less pain after surgery while still allowing the surgeon to do the operation safely.
London, OntairoAges 18 years+ - NCT04991389RecruitingPhase 4
Test a breathing study plan for kids with sleep apnea after surgery
This trial studies how to improve outcomes for children who still have obstructive sleep apnea after having their tonsils and adenoids removed. It uses computer modeling (based on breathing/airflow) and may include a special breathing gas during testing in some parts of the study.
Cincinnati, OhioAges 3–18 - NCT04992871Recruiting
Swiss Cerebral Palsy Registry
This registry study collects information about people with cerebral palsy in Switzerland. It helps researchers better understand CP and related needs over time, which can support future care and studies.
AarauAges birth+ - NCT04994756Recruiting
Stroke and brain blood-vessel procedure registry study
This study collects information from people who undergo a procedure for a problem in brain or blood vessels (such as stroke-related vessel blockage). It does not test a new drug; it helps doctors understand outcomes and care patterns after these procedures.
Birmingham, AlabamaAges 1–120 - NCT04995068Recruiting
Predicting Brain Lesion Risk After Mild Head Injury
This trial studies how to predict who may develop small brain injuries seen on CT scans after a mild traumatic brain injury. It may help doctors decide who needs closer monitoring or follow-up imaging.
StockholmAges 15 years+ - NCT04997109Recruiting
Telemedicine for early constraint therapy in young children with CP
This trial studies a home-based (telemedicine) version of a therapy called constraint therapy for very young babies at risk for or diagnosed with cerebral palsy (CP). The goal is to improve how well the affected arm/hand works by encouraging use of the more affected side.
Atlanta, GeorgiaAges 4 months–1.1 years - NCT04997317RecruitingPhase 1/Phase 2
Lu-177 targeting drug for returning or growing meningioma
This Phase 1/2 study tests a targeted radioactive medicine (Lu-177-satoreotide) for meningiomas that keep coming back or keep growing. It works only if tumor imaging shows the tumor has the right “target” signal, and it aims to see how well it can control the disease and how safe it is.
Basel, Canton of Basel-CityAges 18 years+ - NCT04997642Recruiting
Parkinson’s patient database for memory and movement tracking
This study builds a research database of people who receive care for Parkinson’s disease, including those with mild memory problems or dementia. It aims to collect consistent information that researchers can use to better understand Parkinson’s and related thinking changes.
Philadelphia, PennsylvaniaAges 18 years+ - NCT04998357Recruiting
Autologous mitochondrial transplant after acute stroke complications
This trial studies whether giving your own mitochondria (cell energy parts) can improve recovery after certain emergencies in the brain, such as blocked brain blood vessels or dangerous vessel spasm after a brain bleed. You might be considered if you can safely receive standard procedures and also get a brain MRI.
Seattle, WashingtonAges 18–85 - NCT04998396RecruitingPhase 1/Phase 2
Gene therapy trial for Canavan disease in young children
This Phase 1/2 trial tests an AAV9 gene therapy to treat Canavan disease. It aims to improve disease-related findings in children whose genetic test confirms ASPA gene changes.
Oakland, CaliforniaAges Up to 2.5 years - NCT05000528Recruiting
Program teaching for long-term insomnia patients
This trial tests whether a structured patient education program helps people with chronic insomnia sleep better and feel better. You would likely learn sleep-focused strategies and receive support aimed at improving sleep habits.
NîmesAges 18 years+ - NCT05003388RecruitingPhase 1
Safety study of IV stem cells from donor umbilical cord
This early study tests whether an IV infusion of donor-derived stem cells is safe for people with multiple sclerosis. It mainly focuses on side effects and safety, not whether it improves MS symptoms yet.
St John'sAges Any age - NCT05004233Recruiting
Antiplatelet treatment imaging test for stroke patients
This study uses special microscope imaging (transmission electron microscopy) to look at tiny changes in platelets before and after starting an antiplatelet medicine. It’s testing whether platelets show clear structural signs around the start of treatment for a specific type of stroke.
Saint-EtienneAges 18 years+ - NCT05004129RecruitingPhase 2/Phase 3
Tideglusib for genetic childhood myotonic dystrophy
This trial studies how safe and effective tideglusib is for children and young adults with congenital or childhood-onset myotonic dystrophy type 1 (DM1). It may help researchers learn whether the medicine improves symptoms while tracking side effects closely.
Little Rock, ArkansasAges 6–45 - NCT05005026Recruiting
Online walking program to ease nerve pain after spinal cord injury
This study tests a virtual, at-home walking exercise program to reduce long-lasting nerve pain after spinal cord injury. It may help if your pain has been present for months and you can safely use the online walking sessions without significant side effects.
Birmingham, AlabamaAges 18 years+ - NCT05004493Recruiting
Plasma exchange patient registry and sample collection
This study collects information and blood or other samples from people who are getting plasma exchange therapy. The goal is to build a registry (a organized database) that researchers can use to better understand and improve care.
Iowa City, IowaAges 12–99 - NCT05004610RecruitingPhase 2
Hypertonic lactate treatment after cardiac arrest
This trial studies whether giving a specific IV fluid (hypertonic lactate) soon after resuscitation from cardiac arrest can improve recovery. It is for adults who remain in a deep unresponsive state after return of spontaneous circulation.
Brussels, BelgiumAges 18 years+ - NCT05004987RecruitingPhase 4
Study brain and blood changes in older adults with depression
This study looks at how a brain protein linked to Alzheimer’s disease changes over time in older adults who have major depression but no major memory problems. It involves brain scans, blood and urine tests, and a spinal fluid sample to better understand the connection between depression and brain aging.
New York, New YorkAges 60 years+ - NCT05006859Recruiting
Wheelchair positioning for people with neuromuscular conditions
This trial looks at improving wheelchair positioning for people with neuromuscular diseases. Better positioning may help comfort, safety, and support day-to-day movement in a wheelchair.
AincourtAges 8 years+ - NCT05007990Recruiting
Interview study of caregiving networks over a person’s life
This study uses interviews and questionnaires to better understand who makes up a caregiver’s support network when caring for someone with a long-term health condition. Your answers may help researchers understand how caregiving changes over time and across different health situations.
Bethesda, MarylandAges 18–100 - NCT05008770Recruiting
Test diet and gut changes in older adults with muscle loss
This study looks at how gut changes (including inflammation) may relate to muscle problems in older adults. You may be invited to provide stool (feces) samples and undergo further testing after a screening visit.
LeuvenAges 65 years+ - NCT05008705Recruiting
Protein and muscle stimulation for hospitalized seniors
This trial tests whether increasing protein intake plus using a gentle electrical muscle stimulation device can help maintain or build muscle mass in older adults while they are hospitalized. It may help prevent muscle loss that can happen after short hospital stays.
São PauloAges 65 years+
Common questions
- How many brain & nervous system clinical trials are recruiting?
- Clin2 is tracking 12,425 recruiting neurology studies from the U.S. registry right now, out of 19,436 we cover in this area in total.
- What does “Brain & nervous system” cover here?
- Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We group each study into brain & nervous system based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a brain & nervous system trial near me?
- Use the search to filter brain & nervous system studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.