Neurology
Brain & nervous system clinical trials
Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We’re tracking 11,952 recruiting studies in this area right now.
By phase
- Not applicable9,355
- Phase 2761
- Phase 1558
- Phase 3514
- Phase 4339
- Phase 1/Phase 2300
- Phase 2/Phase 3125
Top conditions
- Stroke798
- Parkinson Disease395
- Alzheimer Disease338
- Multiple Sclerosis328
- Dementia226
- Epilepsy193
- Ischemic Stroke190
- Insomnia159
- Traumatic Brain Injury151
- Obstructive Sleep Apnea142
- Spinal Cord Injuries142
- Acute Ischemic Stroke138
- Sarcopenia134
- Mild Cognitive Impairment127
- Cerebral Palsy119
- Pain Management116
- Migraine107
- Fibromyalgia104
Leading sponsors
- Beijing Tiantan Hospital124
- Assistance Publique - Hôpitaux de Paris109
- Riphah International University105
- Mayo Clinic98
- VA Office of Research and Development92
- Xuanwu Hospital, Beijing89
- Hospices Civils de Lyon77
- Johns Hopkins University69
- University of Minnesota63
- Washington University School of Medicine63
Where studies are running
- California661
- Massachusetts305
- New York295
- Florida272
- Texas266
- Maryland248
- Alabama207
- Arizona206
- Illinois181
- Pennsylvania177
Recruiting studies11,952 total
- NCT07420192Recruiting
A study on nerve surgery for pain after leg amputation
This trial tests a surgery called RPNI to treat painful nerve growths (neuromas) in people who have lost a leg. The goal is to reduce severe pain and improve the ability to use a prosthetic limb.
Ankara, AnkaraAges 18–70 - NCT07420374Recruiting
Outpatient stroke care for older patients
This study tests whether older people with minor strokes or warning signs can be safely treated at home or in an outpatient clinic instead of staying in the hospital. It may be a good fit if you recently had a mild stroke and do not need complex medical care.
HeidelbergAges 60 years+ - NCT07419997Recruiting
Observational study on clot-busting drugs beyond the usual window
This study looks at patients who received a clot-busting drug (intravenous thrombolysis) for their stroke 4.5 to 24 hours after symptoms started. It aims to see how well this works and what happens to them, using data that has already been collected.
BeijingAges 18 years+ - NCT07419152Recruiting
Yoga for chronic insomnia
This study tests whether yoga can help people with chronic insomnia sleep better. You will practice yoga regularly and see if it improves your sleep quality.
New Delhi, National Capital Territory of DelhiAges 18–65 - NCT07418944Recruiting
Surgery vs. non-surgery for leg pain from a slipped disc
This trial compares surgery to non-surgical treatments for people with leg pain caused by a lumbar disc herniation (slipped disc). It tests if surgery provides better relief after at least 6 weeks of symptoms.
HelsinkiAges 18–60 - NCT07417046Recruiting
Fluoxetine and eye patching for lazy eye treatment
This study tests whether a combination of a medicine (fluoxetine) and eye patching can improve vision in people with lazy eye (amblyopia). It uses special eye scans and brain wave tests to see how well the treatment works for different ages.
Minya, Minya GovernorateAges 10 years+ - NCT07418775Recruiting
Meningioma Study: Genes, Health & Life
This study looks at how your tumor's genes, personal health habits, and other factors affect your long-term health after a meningioma diagnosis. You'll be asked to complete surveys about your health and experiences—no new treatments or procedures are involved.
San Francisco, CaliforniaAges 18 years+ - NCT07417137Recruiting
Long-term study of Angelman syndrome
This study follows people with Angelman syndrome over time to learn more about the condition. It does not test any new treatments, but you need a parent or caregiver to come with you to all visits.
Lexington, MassachusettsAges 1 year+ - NCT07420400Recruiting
Detecting heart shunts without needles
This trial uses a specialized ultrasound test (TEE with bubble study) to find a small opening in the heart called a PFO. It may help people who need this test to check for causes of certain health problems.
La Jolla, CaliforniaAges 18 years+ - NCT07417280Recruiting
Focused ultrasound for neurological disorders
This trial tests a gentle ultrasound treatment (LIFUS) for people with various brain conditions like epilepsy, tumours, or movement disorders. It aims to see if this non-invasive approach can help where other treatments are being used.
Toronto, OntarioAges 18–85 - NCT07423377Recruiting
Vibration device for fibromyalgia pain
This trial tests if a device that delivers small vibrations to your ear can help reduce pain from fibromyalgia. You'll use the device as directed and answer online questions about your pain before and after.
New York, New YorkAges 18 years+ - NCT07424846RecruitingPhase 2/Phase 3
Xylitol gum to prevent gum disease and early birth
This trial tests if chewing xylitol gum during pregnancy can reduce gum disease and preterm birth. You would chew gum after meals and attend dental visits and follow-ups.
LilongweAges Any age - NCT07417072Recruiting
Brain tumor drug testing using 3D models in children
This study creates 3D models from brain tumor tissue of children aged 3-18 to test how different drugs might work against their specific tumor. The goal is to find more personalized treatments.
Florence, FirenzeAges 3–18 - NCT07417943Recruiting
Brain stimulation to improve movement in hereditary spastic paraplegia
This study tests whether a non-invasive brain stimulation technique (called neuromodulation) can improve walking, balance, and other movements in adults with hereditary spastic paraplegia (HSP). It may be a good fit if you can walk with or without help, have stable spasticity medications, and don't have a pacemaker or epilepsy.
Lexington, KentuckyAges 18 years+ - NCT07416890RecruitingPhase 2
Study of thiotepa, pirtobrutinib, and sintilimab for CNS lymphoma
This trial tests a combination of three drugs for people with central nervous system (CNS) lymphoma that has come back or not responded to treatment, or for those who cannot take standard chemotherapy. The goal is to see if this new combination is safe and effective.
Hangzhou, ZhejiangAges 18–80 - NCT07420153Recruiting
Arm cuff treatment before surgery to prevent confusion
This study tests whether using a blood pressure cuff on the arm before surgery (called remote ischemic preconditioning) can help prevent confusion (delirium) after surgery. It is for older adults having planned non-cardiac surgery who are at risk for delirium.
Hamburg, Free and Hanseatic City of HamburgAges 50 years+ - NCT07423390RecruitingPhase 3
Vitamin B12 to prevent nerve damage from chemo
This trial tests if taking mecobalamin (a form of vitamin B12) can prevent or reduce nerve pain and numbness caused by taxane chemotherapy. It may help people getting chemo for several types of cancer.
Xining, QinghaiAges 18 years+ - NCT05679271Recruiting
Stent treatment for low-grade dural AV fistula causing ringing
This trial tests whether placing a small tube (stent) inside a brain vein-sinus can reduce a pulsating ringing sound caused by a “dural arteriovenous fistula” (DAVF). It’s for people whose tinnitus matches the DAVF location and who meet imaging and medication safety requirements.
BordeauxAges 18 years+ - NCT06266234Recruiting
Understanding infantile spasms with computer analysis of brain recordings
This study looks at brain recordings (video EEG) from babies and children who have had infantile spasms. It uses a computer program to better understand those spasms, which may help doctors diagnose and treat them more effectively.
GarchesAges Up to 3 years - NCT06615115Recruiting
Focus instructions for balance in Parkinson's rehab
This study looks at whether different types of instructions (like focusing on your movements) can help improve balance for people with Parkinson's. It might help you move better and feel more steady.
IstanbulAges 50–70 - NCT06627426Recruiting
Virtual reality for helping patients understand brain surgery
This trial uses virtual reality to help you better understand your upcoming brain surgery, such as for an aneurysm, abnormal blood vessels, or a tumor. It aims to improve how information is given before surgery.
BaselAges 18–75 - NCT06782815Recruiting
Acupuncture for stress-related insomnia in young adults
This trial tests whether specific acupuncture points can improve sleep in people with insomnia linked to stress and mood. It focuses on adults under 40 who have had trouble sleeping for at least two weeks.
Hangzhou, ZhejiangAges 18–40 - NCT06730763Recruiting
Brain stimulation to reduce fall risk in children with cerebral palsy
This study tests whether a gentle, non-invasive brain stimulation (called tDCS) can help children with cerebral palsy (spastic hemiplegia) improve their balance and reduce falls. The goal is to see if it makes walking safer and easier.
Giza, Giza GovernorateAges 8–12 - NCT06796725Recruiting
Study of TMS for migraine guided by brain imaging
This study tests whether repetitive transcranial magnetic stimulation (rTMS), guided by magnetoencephalography (MEG), can help people with frequent migraines or tension-type headaches. If you have headaches 15 or more days per month, this treatment might reduce your pain.
ShanghaiAges 15–50
Common questions
- How many brain & nervous system clinical trials are recruiting?
- Clin2 is tracking 11,952 recruiting neurology studies from the U.S. registry right now, out of 18,491 we cover in this area in total.
- What does “Brain & nervous system” cover here?
- Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We group each study into brain & nervous system based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a brain & nervous system trial near me?
- Use the search to filter brain & nervous system studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.