Neurology
Brain & nervous system clinical trials
Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We’re tracking 12,425 recruiting studies in this area right now.
By phase
- Not applicable9,762
- Phase 2784
- Phase 1574
- Phase 3535
- Phase 4342
- Phase 1/Phase 2305
- Phase 2/Phase 3123
Top conditions
- Stroke845
- Parkinson Disease426
- Multiple Sclerosis343
- Alzheimer Disease341
- Dementia226
- Ischemic Stroke200
- Epilepsy197
- Obstructive Sleep Apnea155
- Spinal Cord Injuries154
- Insomnia153
- Sarcopenia149
- Traumatic Brain Injury149
- Acute Ischemic Stroke139
- Cerebral Palsy131
- Mild Cognitive Impairment129
- Pain Management114
- Migraine112
- Amyotrophic Lateral Sclerosis108
Leading sponsors
- Beijing Tiantan Hospital133
- Riphah International University125
- Assistance Publique - Hôpitaux de Paris112
- Mayo Clinic99
- Xuanwu Hospital, Beijing94
- VA Office of Research and Development93
- Hospices Civils de Lyon79
- Johns Hopkins University70
- National Taiwan University Hospital70
- University of Minnesota64
Where studies are running
- California678
- Massachusetts300
- New York292
- Florida275
- Texas267
- Maryland245
- Arizona213
- Alabama211
- Illinois189
- Pennsylvania178
Recruiting studies12,423 total
- NCT05413655RecruitingPhase 2
Oral drug for mild Alzheimer’s disease symptoms
This Phase 2 trial tests an oral medicine (EX039) to see if it can help people with mild Alzheimer’s disease. It focuses on slowing or improving thinking and memory problems over time.
TaipeiAges 50–80 - NCT05413616Recruiting
Personalized nutrition and activity therapy for older hospital patients
This study tests whether a tailored nutrition plan plus a step-by-step exercise program can improve physical strength and performance in older adults in the hospital. It compares these interventions to the usual hospital care you would normally get.
Nijmegen, GelderlandAges 65 years+ - NCT05414903Recruiting
Reading support study for children with balance/hearing loss
This study looks at how children with vestibular (balance) and/or hearing loss learn to read. It may help researchers understand what reading supports work best for children who have trouble with balance and sound processing.
Omaha, NebraskaAges 7–18 - NCT05414292Recruiting
Testing rapamycin effect on exercise muscle function in older adults
This study looks at how rapamycin (a medication that affects a growth signal in the body) changes muscle responses when older adults do resistance exercise. It may help researchers understand whether this treatment could improve or alter muscle function with aging.
DerbyAges 50–90 - NCT05414708Recruiting
Art therapy for veterans with PTSD symptoms
This study tests whether art therapy can improve emotional well-being in military members who have significant PTSD symptoms. You would answer questionnaires and likely take part in art-making sessions as part of the treatment being studied.
Bethesda, MarylandAges 18–64 - NCT05415020Recruiting
Behavior program for chronic migraine
This trial tests a behavioral (talk/skills-based) program to help people with chronic migraine. It may help reduce migraine frequency or improve day-to-day coping.
Phoenix, ArizonaAges 18 years+ - NCT05416385Recruiting
Stress echo scan with special contrast to study carotid plaque
This study uses a heart stress ultrasound test, plus a contrast dye, to look for new blood vessel growth inside carotid plaque (the buildup in neck arteries). It may help doctors better judge the risk of stroke and determine which people need closer care.
Calgary, AlbertaAges 18 years+ - NCT05415501Recruiting
Sentence practice training for people with post-stroke aphasia
This study tests a training program designed to help people with aphasia—trouble making sentences—after a stroke. It may help improve sentence use and communication by practicing targeted sentence production skills.
West Lafayette, IndianaAges 21–85 - NCT05416567Recruiting
Embolization for meningioma using blood-vessel blockage
This trial studies whether a procedure that blocks the tumor’s blood supply (embolization) can help people with a typical meningioma that is growing or causing symptoms. It may help shrink or control the tumor by cutting off its main blood supply.
TrondheimAges 18 years+ - NCT05416684Recruiting
PEEK vs titanium skull repair after brain surgery
This is an observation study that compares outcomes after two types of skull repair: PEEK and titanium. It may help doctors understand which option works best and how patients recover, without requiring an experimental treatment plan.
Shanghai, Shanghai MunicipalityAges 18–65 - NCT05418218Recruiting
International headache registry for people with headache diagnoses
This study collects information from people who have headaches to better understand different headache types. You may help researchers by keeping headache records and allowing follow-up over time.
Hangzhou, ZhejiangAges 4–99 - NCT05418010RecruitingPhase 2
Natalizumab treatment for early multiple sclerosis-like symptoms
This Phase 2 study tests natalizumab to treat people who have had a first episode of symptoms suggestive of multiple sclerosis. It aims to see whether the treatment can help after early “demyelination” changes are seen on brain MRI.
LondonAges 18–55 - NCT05418894Recruiting
Study brain signals and improve treatment-resistant depression
This trial studies how brain activity relates to feelings and depression, using brain electrodes to measure signals. It’s meant for people with long-lasting, treatment-resistant major depression who may need stimulation while continuing psychiatric care.
Houston, TexasAges 22–70 - NCT05419076RecruitingPhase 2
SRS radiation for small cell lung cancer with brain spread
This Phase 2 trial tests a type of focused radiation (stereotactic radiosurgery, or SRS) for people with small cell lung cancer that has spread to the brain. It looks at whether this approach can treat brain metastases when the cancer has limited to a certain number of spots.
Basking Ridge, New JerseyAges 18 years+ - NCT05423600Recruiting
Telehealth spinal stimulation plus exercise for high-level incomplete SCI
This study tests whether a home, therapist-guided exercise program combined with a spinal stimulation device (with or without limited blood flow) can improve movement and function in people with incomplete tetraplegia. It may help your muscles respond better, but participation depends on safety checks and your ability to do exercises by video.
Richmond, VirginiaAges 18–70 - NCT05422534RecruitingPhase 3
CoQ10 plus exercise for people with advanced kidney disease
This trial tests whether a supplement called CoQ10, along with supervised exercise, can improve how the body uses energy in people on chronic dialysis. It may help with muscle function and overall health if your heart and dialysis situation are stable enough.
Sacramento, CaliforniaAges 18–75 - NCT05423171Recruiting
Extra hand-focused therapy for children with cerebral palsy
This trial tests an intensive therapy program that trains both hands together to improve hand use in children with cerebral palsy. It may help your child with everyday hand and arm skills, but it also requires meeting certain health, eye, and recent-treatment limits.
QuébecAges 6–17 - NCT05424302Recruiting
Home virtual reality therapy for vestibular problems by location
This study looks at how well a home-based virtual reality (VR) vestibular therapy works for people with ongoing (chronic) balance problems, and whether results differ based on where the problem is in the inner ear. It may help your care team understand who benefits most from VR therapy.
Vancouver, British ColumbiaAges 18 years+ - NCT05423860Recruiting
HALO prostate study for men with early prostate cancer
This trial studies HALO, a new “human analytics” approach, in men with early-stage prostate cancer. It may help doctors better assess or guide care using MRI and biopsy findings, before or around initial treatment.
Indian Wells, CaliforniaAges 45–90 - NCT05424016Recruiting
Propranolol for brain blood-vessel tumors in VHL
This trial studies whether propranolol, a beta-blocker medicine, can help people with VHL who have non-urgent hemangioblastomas in the brain/spinal cord. It aims to see if the medication is safe and beneficial without needing immediate surgery.
Le Kremlin-BicêtreAges 18 years+ - NCT05424172Recruiting
Smartphone coaching to boost exercise after spinal cord injury
This study tests a smartphone program and coaching to help people with spinal cord injury follow recommended exercise routines. It may help you increase how much you exercise and improve adherence to exercise guidelines.
Chicago, IllinoisAges 18–80 - NCT05424978Recruiting
Standardized green-channel treatment for acute stroke care
This study tests a structured, fast way of treating people who have a new ischemic stroke (a stroke caused by a blocked blood vessel). It may help because it focuses on getting the right stroke treatments quickly and consistently.
Xi'an, ShaanxiAges 18–100 - NCT05425004RecruitingPhase 2
Cabozantinib for recurrent or worsening meningioma tumors
This Phase 2 trial studies cabozantinib, a targeted pill medicine, for meningioma that has come back or is getting worse after standard treatment like surgery or radiation. It aims to shrink tumors and slow progression when other options may have limited benefit.
Miami, FloridaAges 18 years+ - NCT05425615Recruiting
Testing brain stimulation to improve language after left stroke
This study tests a form of brain stimulation (TMS) in people who had a stroke affecting the left side of the brain. It aims to understand whether stimulation can help with language processing tasks at least a month after stroke.
Milwaukee, WisconsinAges 18–85
Common questions
- How many brain & nervous system clinical trials are recruiting?
- Clin2 is tracking 12,425 recruiting neurology studies from the U.S. registry right now, out of 19,436 we cover in this area in total.
- What does “Brain & nervous system” cover here?
- Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We group each study into brain & nervous system based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a brain & nervous system trial near me?
- Use the search to filter brain & nervous system studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.