Neurology
Brain & nervous system clinical trials
Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We’re tracking 12,425 recruiting studies in this area right now.
By phase
- Not applicable9,762
- Phase 2784
- Phase 1574
- Phase 3535
- Phase 4342
- Phase 1/Phase 2305
- Phase 2/Phase 3123
Top conditions
- Stroke845
- Parkinson Disease426
- Multiple Sclerosis343
- Alzheimer Disease341
- Dementia226
- Ischemic Stroke200
- Epilepsy197
- Obstructive Sleep Apnea155
- Spinal Cord Injuries154
- Insomnia153
- Sarcopenia149
- Traumatic Brain Injury149
- Acute Ischemic Stroke139
- Cerebral Palsy131
- Mild Cognitive Impairment129
- Pain Management114
- Migraine112
- Amyotrophic Lateral Sclerosis108
Leading sponsors
- Beijing Tiantan Hospital133
- Riphah International University125
- Assistance Publique - Hôpitaux de Paris112
- Mayo Clinic99
- Xuanwu Hospital, Beijing94
- VA Office of Research and Development93
- Hospices Civils de Lyon79
- Johns Hopkins University70
- National Taiwan University Hospital70
- University of Minnesota64
Where studies are running
- California678
- Massachusetts300
- New York292
- Florida275
- Texas267
- Maryland245
- Arizona213
- Alabama211
- Illinois189
- Pennsylvania178
Recruiting studies12,423 total
- NCT05394987Recruiting
Testing new glasses and vision function in amblyopia adults
This study looks at how changing your glasses prescription affects vision and visual function in adults with amblyopia (often called “lazy eye”). It may help researchers understand which optical correction best supports clearer, more balanced vision.
Waterloo, OntarioAges 18–39 - NCT05395195RecruitingPhase 3
Erythropoietin for newborn brain injury in low-resource settings
This Phase 3 trial studies whether erythropoietin (a medicine related to red-blood-cell growth) can improve outcomes for newborns with moderate to severe brain injury after birth. The study focuses on babies born in low- and middle-income countries and aims to reduce harm from this early brain condition.
DhakaAges 1 hour–6 hours - NCT05395715Recruiting
Nerve stimulation study for cubital tunnel nerve compression
This study tests whether a specific type of electrical nerve stimulation (conditioning electrical stimulation) can improve outcomes for people with cubital tunnel syndrome. It is mainly for adults with more severe nerve damage based on specialist test results, and who have not had prior surgery for this problem.
Edmonton, AlbertaAges 18–79 - NCT05395624RecruitingPhase 1/Phase 2
Safety imaging study of a PET tracer in ALS, Alzheimer, MS, Parkinson
This early-phase study tests the safety of a radioactive tracer (“18F-OP-801”) and how the tracer moves through the body (biodistribution) in people with ALS, Alzheimer’s disease, multiple sclerosis, Parkinson’s disease, and in healthy volunteers. It also measures how the body processes the tracer (“pharmacokinetics”) to support future studies.
San Francisco, CaliforniaAges 18–80 - NCT05395598Recruiting
Long-term follow-up for large aortic root aneurysm risks
This study follows people with an enlarged aortic root to track how often serious complications happen over time. It may help doctors understand risk and improve care by observing outcomes for up to five years.
Lille, Please Choose...Ages 45–80 - NCT05397405Recruiting
Improving cholesterol control after narrowing in brain arteries
This study looks at strategies to improve cholesterol treatment in adults whose brain arteries are narrowed and who have had symptoms. Better cholesterol management may help reduce future problems related to this condition.
Nanjing, JiangsuAges 18–85 - NCT05397639RecruitingPhase 3
Masupirdine trial for agitation in Alzheimer’s dementia
This Phase 3 study tests masupirdine to see if it can reduce agitation in people with Alzheimer’s-type dementia. If you have Alzheimer’s dementia with confirmed agitation, joining could help researchers find better treatment options.
Anaheim, CaliforniaAges 50–90 - NCT05397873Recruiting
Biofeedback training to improve vision in hemianopia
This trial tests whether guided “biofeedback” training can help people with hemianopia (a vision field loss) improve how they use their remaining vision. You may be asked to complete vision testing and practice exercises while receiving feedback based on your responses.
Toronto, OntarioAges 18–90 - NCT05400499Recruiting
Deep brain stimulation study in Parkinson’s visuomotor function
This trial studies how deep brain stimulation affects hand-eye (visuomotor) coordination in people with Parkinson’s. It may help researchers understand whether the stimulation settings change movement control for daily tasks.
Cleveland, OhioAges Any age - NCT05402761Recruiting
Nurse-guided sleep program for insomnia after brain injury
This trial studies whether nurse-guided behavioral sleep therapy can improve insomnia in people recovering after a traumatic brain injury (TBI). It may help you sleep better by targeting sleep habits and insomnia symptoms.
TaipeiAges 20–65 - NCT05402163Recruiting
Testing adaptive DBS for gait, balance, and speech
This trial looks at a new type of Parkinson’s brain stimulation (adaptive DBS) to help with disabling walking, balance, and/or speech problems. It also requires replacing your DBS battery because the researchers need to test the new system’s signals.
Toronto, OntarioAges 18–80 - NCT05402488Recruiting
Studying sleep recovery in adults with neurodegeneration
This study looks at how sleep “recovery” works in people with neurodegenerative diseases (conditions where abnormal proteins build up). It uses sleep recordings and sounds during sleep to see how sleep patterns relate to outcomes.
Zurich, Canton of ZurichAges 18 years+ - NCT05402280Recruiting
Study of sleep problems and delirium in hospitalized adults
This study looks at how sleep disturbances may be connected to delirium (sudden confusion) in people staying in the hospital. It may help researchers find ways to prevent delirium by understanding sleep and early warning signs.
Ostrava, Česká RepublikaAges 18 years+ - NCT05402813Recruiting
Study of hearing loss in children with GJB2 or OTOF gene changes
This study follows children with hearing loss caused by changes in specific genes (GJB2 or OTOF). It helps researchers understand how hearing develops over time and how children may do with or without cochlear implants.
ParisAges Up to 16 years - NCT05404230Recruiting
Preventing nerve damage from oxaliplatin in the hands and feet
This study looks at ways to prevent numbness or nerve pain in the hands and feet that can happen from oxaliplatin treatment. It includes people with colon or rectal cancer who will be getting standard chemotherapy with capecitabine plus oxaliplatin.
AalborgAges 18 years+ - NCT05404581Recruiting
Insula brain stimulation for long-term nerve pain
This trial tests whether stimulating a specific brain area (the insula) can reduce chronic nerve pain. It is for people whose pain has lasted at least 6 months and has not improved enough with several pain medicines and other procedures.
Charlottesville, VirginiaAges 18–80 - NCT05405075Recruiting
Alzheimer’s research study with brain tests and blood samples
This study supports Alzheimer’s research by collecting health and thinking (cognitive) test results and blood samples to study genetics and biomarkers. You may be enrolled if you’re age 40 or older and can do these checkups, even if you have mild memory problems or dementia.
Phoenix, ArizonaAges 40 years+ - NCT05406167Recruiting
Tracking quality of life during radiotherapy with a new system
This study collects information about how you feel and how treatment is delivered while you receive radiotherapy using the RefleXion Medical radiotherapy system. It may help doctors improve care and better understand what affects quality of life during treatment.
Duarte, CaliforniaAges Any age - NCT05406349Recruiting
Study of brain activity for space memory using epilepsy implants
This study looks at how your brain represents locations in space, including how it relates to you (beyond your “self”). It uses special epilepsy-related implants or procedures to record brain activity, which may help researchers understand spatial thinking.
Boston, MassachusettsAges 18–70 - NCT05407324RecruitingPhase 2
Dazucorilant for ALS patients at higher risk of faster progression
This Phase 2 study tests whether dazucorilant can slow or improve outcomes in people with amyotrophic lateral sclerosis (ALS) who are likely to progress more quickly. You may be able to join if you meet specific ALS type and risk-score requirements and your health tests and medications fit the study rules.
Phoenix, ArizonaAges 18 years+ - NCT05407857Recruiting
Study to help prevent memory decline in adults over 60
This study looks for ways to lower the risk of developing dementia and improve thinking skills in people over 60. You may be eligible if you do not have dementia but have early warning signs of memory or thinking changes.
New Taipei CityAges 60–90 - NCT05410457Recruiting
Study different treatments after ischemic stroke
This trial looks at which treatment approach after an ischemic stroke (a stroke caused by a blocked blood vessel) may lead to better outcomes. It may help doctors better choose treatments that improve recovery and prognosis.
Nanjing, JiangsuAges 18 years+ - NCT05411029Recruiting
Study on sleep problems in Somali adults
This study looks at how disrupted sleep shows up in Somali adults without certain health conditions. It may help researchers understand sleep patterns in this community and improve future sleep support.
Rochester, MinnesotaAges 18–70 - NCT05413291Recruiting
Study of movement disorders over time
This study follows people (or family members of people) who have or might have a movement disorder to better understand how symptoms change over time. You may be asked to attend study visits and complete study procedures for the duration of the study.
Bethesda, MarylandAges 2–100
Common questions
- How many brain & nervous system clinical trials are recruiting?
- Clin2 is tracking 12,425 recruiting neurology studies from the U.S. registry right now, out of 19,436 we cover in this area in total.
- What does “Brain & nervous system” cover here?
- Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We group each study into brain & nervous system based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a brain & nervous system trial near me?
- Use the search to filter brain & nervous system studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.