Neurology
Brain & nervous system clinical trials
Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We’re tracking 11,952 recruiting studies in this area right now.
By phase
- Not applicable9,355
- Phase 2761
- Phase 1558
- Phase 3514
- Phase 4339
- Phase 1/Phase 2300
- Phase 2/Phase 3125
Top conditions
- Stroke798
- Parkinson Disease395
- Alzheimer Disease338
- Multiple Sclerosis328
- Dementia226
- Epilepsy193
- Ischemic Stroke190
- Insomnia159
- Traumatic Brain Injury151
- Obstructive Sleep Apnea142
- Spinal Cord Injuries142
- Acute Ischemic Stroke138
- Sarcopenia134
- Mild Cognitive Impairment127
- Cerebral Palsy119
- Pain Management116
- Migraine107
- Fibromyalgia104
Leading sponsors
- Beijing Tiantan Hospital124
- Assistance Publique - Hôpitaux de Paris109
- Riphah International University105
- Mayo Clinic98
- VA Office of Research and Development92
- Xuanwu Hospital, Beijing89
- Hospices Civils de Lyon77
- Johns Hopkins University69
- University of Minnesota63
- Washington University School of Medicine63
Where studies are running
- California661
- Massachusetts305
- New York295
- Florida272
- Texas266
- Maryland248
- Alabama207
- Arizona206
- Illinois181
- Pennsylvania177
Recruiting studies11,952 total
- NCT06843616Recruiting
Study of a disposable brain clot removal scope for bleeding stroke
This study tests a new disposable tube with a camera (endoscope) that doctors use to remove a blood clot from the brain after a bleeding stroke. It is designed for people who are stable enough for surgery and whose bleed is in a part of the brain that is reachable with this tool.
Guiyang, GuizhouAges 18–80 - NCT03948373Recruiting
Study of sleep apnea patients with normal blood pressure
This study is looking at a specific sleep-related condition (obstructive sleep apnea) in adults whose blood pressure is not high, and how their blood pressure rhythm changes over the day. If you have sleep apnea, participating could help researchers understand patterns that may affect long-term health.
LleidaAges 18–100 - NCT04974138RecruitingPhase 4
Preventing first stroke in people with high-risk blood pressure
This trial tests whether a study medicine regimen can help prevent a first stroke in people with hard-to-control “high homocysteine” risk factors linked to a specific gene type. You may qualify if you have certain blood pressure levels, a specific MTHFR gene result, and related blood test findings.
Bengbu, AnhuiAges 45–74 - NCT05444907Recruiting
Testing treatment response in DBS-related mania in Parkinson’s
This study is looking at people with Parkinson’s who developed mania (a high-energy mood episode) after deep brain stimulation (DBS) was turned on or its settings were changed. It may help doctors better understand why this happens and how to manage it safely.
LisbonAges 18 years+ - NCT05755919Recruiting
Brain mapping during epilepsy surgery with special brain electrodes
This study looks at how to map brain function in people having epilepsy surgery by recording brain signals using special electrodes placed on or inside the brain. It may help doctors better understand which brain areas cause seizures.
Detroit, MichiganAges 6 months–21 years - NCT05413655RecruitingPhase 2
Oral drug for mild Alzheimer’s disease symptoms
This Phase 2 trial tests an oral medicine (EX039) to see if it can help people with mild Alzheimer’s disease. It focuses on slowing or improving thinking and memory problems over time.
TaipeiAges 50–80 - NCT06127459Recruiting
Virtual reality to help kids with brain injury improve thinking skills
This trial tests if virtual reality exercises can help children aged 8-12 with mild or moderate traumatic brain injury improve their attention and thinking skills. It is designed for children whose challenges were confirmed by a psychologist and who speak Finnish.
OuluAges 8–12 - NCT06320106Recruiting
Navigating abilities in children with cerebral palsy
This study compares how children with cerebral palsy and their peers navigate spaces. It aims to understand differences in orientation and movement skills.
Bosisio Parini, LeccoAges 13 years+ - NCT06486597Recruiting
Metabolism study in children with cerebral palsy
This study looks at how the body uses energy in children with cerebral palsy who have low muscle mass. It compares them to healthy children to understand metabolism better.
Copenhagen, Copenhagen ØAges 2–18 - NCT06387225Recruiting
Study on brain recovery after cardiac arrest
This study is trying to find better ways to predict recovery in people who had a cardiac arrest outside the hospital and are still unconscious in the intensive care unit. It may help doctors give more accurate information to families.
La Roche-sur-YonAges 18 years+ - NCT06847295Recruiting
Spinal cord stimulation for standing and walking after paralysis
This trial tests if a device that sends mild electrical pulses to the spinal cord, combined with daily therapy, can help people with chronic spinal cord injury regain some ability to stand or walk. It also looks at reducing muscle spasms and improving quality of life.
São Paulo, São PauloAges 18–50 - NCT06718920Recruiting
Childhood experiences and quality of life in MS
This study looks at how difficult childhood experiences may affect the quality of life and coping skills of people with multiple sclerosis. By answering questionnaires, you can help researchers understand these connections and find better ways to support patients.
Rome, RMAges 18 years+ - NCT06844734Recruiting
Study of ITB treatment for hereditary spastic paraplegia
This trial tests if a treatment called ITB (intrathecal baclofen) can help reduce muscle stiffness in people with hereditary spastic paraplegia (HSP). Participants will receive the treatment and be followed over time to see how well it works.
Shanghai, Shanghai MunicipalityAges 14–70 - NCT05260125RecruitingPhase 4
Ultrasound-guided shoulder nerve block for stroke pain
This trial compares two ways to deliver a shoulder nerve block to relieve long-lasting shoulder pain after stroke: one guided by ultrasound and one without. It may help if your stroke-related shoulder pain has lasted at least a few months and you may benefit from a targeted pain-relief injection.
BoluAges 25–75 - NCT05540262Recruiting
Edaravone for new anti-AQP4 optic neuritis
This trial tests edaravone, a medicine intended to reduce damage from optic neuritis, in adults whose condition is confirmed by a positive blood test for anti-AQP4 antibodies. It may help people who are in the first month after their first episode to preserve or improve vision.
NanningAges 18–70 - NCT06068036Recruiting
Telehealth program to boost physical activity after stroke
This study tests whether a telehealth program with a wearable activity tracker can help people who have had a stroke become more active. It's designed for those who are ready to start moving more with their doctor's okay.
Belo Horizonte, Minas GeraisAges 18 years+ - NCT06814964RecruitingPhase 1
Intraventricular clot removal with medication after brain bleed
This trial tests a clot-busting drug (rhTNK-tPA) to remove blood from the ventricles (fluid spaces deep in the brain) after a spontaneous brain bleed. It may help patients whose ventricles are blocked by a large clot, reducing pressure and improving recovery.
Beijing, Beijing MunicipalityAges 18–80 - NCT06409754Recruiting
Brain-computer interface for arm recovery after stroke
This trial tests a brain-computer interface system that helps move your arm using electrical stimulation. It is for people who have had a stroke at least 6 months ago and have lasting weakness in one arm.
Mexico City, Mexico CityAges 18 years+ - NCT07354750Recruiting
Parasternal block for pain in pediatric heart surgery
This trial tests whether a nerve block given before a heart surgery incision reduces the need for pain medicine during the operation in children aged 6 months to 7 years having their first heart surgery through the breastbone.
AnkaraAges 6 months–7 years - NCT07357428Recruiting
Brain-computer implant study for severe paralysis or speech loss
This study tests a brain-computer implant that might help people with severe paralysis or speech loss control a computer with their thoughts. It is for people who have trouble moving and speaking due to a progressive disease or injury.
Sacramento, CaliforniaAges 22–75 - NCT07354724RecruitingPhase 1
Study of DNL952 for adults with late-onset Pompe disease
This trial tests a new drug, DNL952, in adults with late-onset Pompe disease. It aims to see if the drug is safe and how it works in the body, with different groups for people currently on enzyme replacement therapy or those who haven't had it in the past year.
Irvine, CaliforniaAges 18–75 - NCT07357285Recruiting
Stroke treatment trial for smaller vessel blockages
This trial tests a new catheter device to remove blood clots from smaller brain arteries in people having a stroke. It aims to see if the device is safe and effective for patients treated within 24 hours of symptoms starting.
BonnAges 18 years+ - NCT07354269RecruitingPhase 4
Polio vaccine study for adolescents and adults
This trial tests a polio vaccine (sIPV) in healthy people aged 7-50 years. It aims to see how safe and effective the vaccine is, and may help protect against polio.
Dingxi, GansuAges 3 months–50 years - NCT07361302RecruitingPhase 3
Tenecteplase for stroke after 4.5 hours
This trial tests a clot-dissolving medicine called tenecteplase for people who had a stroke more than 4.5 hours ago. It may help you recover if given later than usual.
Buenos AiresAges 18 years+
Common questions
- How many brain & nervous system clinical trials are recruiting?
- Clin2 is tracking 11,952 recruiting neurology studies from the U.S. registry right now, out of 18,491 we cover in this area in total.
- What does “Brain & nervous system” cover here?
- Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We group each study into brain & nervous system based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a brain & nervous system trial near me?
- Use the search to filter brain & nervous system studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.