Neurology
Brain & nervous system clinical trials
Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We’re tracking 12,425 recruiting studies in this area right now.
By phase
- Not applicable9,762
- Phase 2784
- Phase 1574
- Phase 3535
- Phase 4342
- Phase 1/Phase 2305
- Phase 2/Phase 3123
Top conditions
- Stroke845
- Parkinson Disease426
- Multiple Sclerosis343
- Alzheimer Disease341
- Dementia226
- Ischemic Stroke200
- Epilepsy197
- Obstructive Sleep Apnea155
- Spinal Cord Injuries154
- Insomnia153
- Sarcopenia149
- Traumatic Brain Injury149
- Acute Ischemic Stroke139
- Cerebral Palsy131
- Mild Cognitive Impairment129
- Pain Management114
- Migraine112
- Amyotrophic Lateral Sclerosis108
Leading sponsors
- Beijing Tiantan Hospital133
- Riphah International University125
- Assistance Publique - Hôpitaux de Paris112
- Mayo Clinic99
- Xuanwu Hospital, Beijing94
- VA Office of Research and Development93
- Hospices Civils de Lyon79
- Johns Hopkins University70
- National Taiwan University Hospital70
- University of Minnesota64
Where studies are running
- California678
- Massachusetts300
- New York292
- Florida275
- Texas267
- Maryland245
- Arizona213
- Alabama211
- Illinois189
- Pennsylvania178
Recruiting studies12,423 total
- NCT05426967Recruiting
Brain stimulation for depression after mild traumatic brain injury
This trial studies a noninvasive brain treatment (rTMS) to reduce depression symptoms in people with past mild traumatic brain injury from military service. It may help by changing brain activity, while also requiring stable mental health care and regular follow-up.
Palo Alto, CaliforniaAges 18–55 - NCT05429983Recruiting
Predicts results from Inspire tongue-stimulation for sleep apnea
This study looks at how breathing mechanics during a sleep-related test (DISE) can help predict how well Inspire tongue (hypoglossal nerve) stimulation will work. It may help your care team choose the best approach and set expectations for improvement.
Baltimore, MarylandAges 18 years+ - NCT05431010Recruiting
Electroacupuncture for walking problems in older people with muscle loss
This study tests whether electroacupuncture (a type of acupuncture that uses a mild electric current) can improve walking ability in older adults with sarcopenia, which means age-related loss of muscle. If it helps, it could make it easier to walk and complete daily activities.
Hangzhou, ZhejiangAges 60–95 - NCT05431101Recruiting
Absorbable versus non-absorbable stitches after carpal tunnel surgery
This study compares two types of stitches used to close the skin after carpal tunnel release surgery. It may help show which stitch type leads to better healing and comfort afterward.
ApeldoornAges 18 years+ - NCT05431595RecruitingPhase 2/Phase 3
Test a less sedating plan for agitated delirium in cancer
This study looks at whether using certain sleep/behavior medicines (called neuroleptics) with anti-seizure medicines can calm agitation from delirium without needing as much of the usual “neuroleptic” medicines. It may help people with advanced cancer who are confused and very restless or hard to settle.
Houston, TexasAges 18 years+ - NCT05433441Recruiting
Parkinson care team program for people living at home
This study tests whether “Parkinson specialized teams” can improve care for people with Parkinson’s disease who live at home, with help from a main family caregiver. It looks at whether specialized support can be followed over time and whether it helps daily functioning.
BordeauxAges 18 years+ - NCT05433103Recruiting
Blood flow restriction training for veterans with multiple sclerosis
This trial tests whether a special exercise method that briefly limits blood flow to the legs can improve strength and walking ability in people with multiple sclerosis (MS). If you have walking limitations, it may help you build fitness with less heavy resistance training—but you must be able to safely use a pressure cuff during testing.
Aurora, ColoradoAges 18–75 - NCT05434065RecruitingPhase 2
Celecoxib for brain bleeding after onset
This Phase 2 trial tests whether celecoxib (an anti-inflammatory medicine) can improve outcomes after an intracerebral hemorrhage (a type of stroke caused by bleeding in the brain). It also studies how the medicine may help the body recover. You would need to start treatment quickly after symptoms begin and meet several safety and bleeding-control requirements.
TaipeiAges 20–80 - NCT05434572Recruiting
Neuromuscular disease biobank for research samples
This trial is building a biobank (a secure research collection) from people with neuromuscular diseases, their families, or healthy volunteers. By joining, you help researchers study these conditions and improve future treatments.
Richmond, VirginiaAges Up to 75 years - NCT05435612Recruiting
Rehab after cochlear implant for one-sided hearing loss
This trial studies how well hearing rehabilitation works after getting a cochlear implant in people with one-sided (single-sided) deafness. It may help your care team understand what rehab results to expect and how to support hearing progress.
Beijing, Beijing MunicipalityAges 12 years+ - NCT05435781RecruitingPhase 4
Hydrocortisone added during stress in people on low-dose prednisolone
This study tests whether adding supplemental hydrocortisone during stressful events can prevent problems in people who develop adrenal insufficiency from long-term prednisolone. It is meant to see if “stress dosing” is safer and helps the body respond to stress.
AarhusAges 50 years+ - NCT05437237Recruiting
AI test to triage stroke patients using EEG in ambulances
This study tests an AI computer algorithm that helps decide how urgently a person with suspected stroke should be treated, using a special brain-wave test (EEG) in the ambulance. It may help teams spot certain stroke patterns faster and route patients to the right care sooner.
Amsterdam, North HollandAges 18 years+ - NCT05439200Recruiting
Video-based treatment for lazy eye in young children
This trial tests whether a video treatment can improve “lazy eye” (amblyopia) in children ages 3–7. It may help if your child’s vision difference is present despite glasses worn consistently, and you’re able to skip the usual patching during the study.
Dallas, TexasAges 3–7 - NCT05439902Recruiting
Tamsulosin for painful urination in women with multiple sclerosis
This trial studies whether tamsulosin can improve painful or difficult urination (dysuria) in women who have multiple sclerosis. It focuses on people whose symptoms are linked to bladder coordination problems, with stable ongoing treatment.
NîmesAges 18 years+ - NCT05440448Recruiting
Patch-free therapy for lazy eye in children
This study tests a patch-free treatment approach for “lazy eye” (amblyopia) in children. It may help some kids improve vision without using traditional eye patches, but it requires a willingness to skip standard patching during the study.
Dallas, TexasAges 3–12 - NCT05444127Recruiting
Study of oral health in people with Wilson’s disease
This study compares oral (mouth and teeth) health in people with Wilson’s disease versus people without it. It aims to see whether Wilson’s disease is linked to specific dental and imaging findings, which could help with future prevention and care.
Ivry-sur-SeineAges 18 years+ - NCT05441280RecruitingPhase 2
Pimavanserin to improve sleep in veterans with PTSD
This Phase 2 trial studies pimavanserin, a medicine meant to improve insomnia, in veterans who also have PTSD. It may help reduce problems with falling asleep, staying asleep, or waking too early that affect daytime functioning.
Houston, TexasAges 18–64 - NCT05443100Recruiting
Testing whole-body cold therapy for metabolic, neurologic, or fibromyalgia pain
This trial studies whether a whole-body cold therapy called “WBC” can help people with certain metabolic conditions, neurologic conditions, or fibromyalgia. You may be able to join if you meet age and weight requirements and don’t have certain medical or safety risks.
Oggebbio, Verbano-Cusio-OssolaAges 18–65 - NCT05443633Recruiting
Brain and speech training for people with aphasia
This study looks at ways to improve language (speaking and understanding) for people with aphasia caused by stroke or dementia, using MRI to study brain function. It may help by testing language-focused approaches and how brain activity changes during treatment.
Tucson, ArizonaAges 21–80 - NCT05443906Recruiting
Home exercise program for people with neurodegenerative conditions
This trial studies whether a home exercise program is safe and helpful for people with certain neurodegenerative conditions, including X-linked adrenoleukodystrophy and DARS2-related disease, as well as some other similar diagnoses. You would be asked to do exercises at home and be assessed on your walking and strength/safety.
Baltimore, MarylandAges 5–75 - NCT05444907Recruiting
Testing treatment response in DBS-related mania in Parkinson’s
This study is looking at people with Parkinson’s who developed mania (a high-energy mood episode) after deep brain stimulation (DBS) was turned on or its settings were changed. It may help doctors better understand why this happens and how to manage it safely.
LisbonAges 18 years+ - NCT05445180Recruiting
Brain scan study of thinking in cannabis users with psychosis
This study uses brain imaging to understand how thinking works in people who use cannabis, comparing those with psychosis to people without psychosis. It may help researchers learn what brain patterns relate to thinking difficulties and how cannabis use fits in.
Montreal, QuebecAges 16–80 - NCT05446584RecruitingPhase 2
Study memory changes in people with past mild head injury
This Phase 2 study looks at how memory problems (amnestic mild cognitive impairment) may relate to a history of a mild traumatic brain injury. It compares people with a past mild head injury to people without one to better understand what might be driving memory symptoms.
Dallas, TexasAges 55 years+ - NCT05450822Recruiting
Personalized testing to guide treatment for epilepsy
This trial uses detailed brain tests to better match people with epilepsy to the right treatment. It may help by using “precision medicine” methods to understand what in the brain is driving seizures.
CopenhagenAges 16–55
Common questions
- How many brain & nervous system clinical trials are recruiting?
- Clin2 is tracking 12,425 recruiting neurology studies from the U.S. registry right now, out of 19,436 we cover in this area in total.
- What does “Brain & nervous system” cover here?
- Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We group each study into brain & nervous system based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a brain & nervous system trial near me?
- Use the search to filter brain & nervous system studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.