Neurology
Brain & nervous system clinical trials
Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We’re tracking 11,975 recruiting studies in this area right now.
By phase
- Not applicable9,368
- Phase 2765
- Phase 1561
- Phase 3516
- Phase 4338
- Phase 1/Phase 2301
- Phase 2/Phase 3126
Top conditions
- Stroke799
- Parkinson Disease395
- Alzheimer Disease339
- Multiple Sclerosis330
- Dementia227
- Epilepsy194
- Ischemic Stroke190
- Insomnia159
- Traumatic Brain Injury151
- Obstructive Sleep Apnea142
- Spinal Cord Injuries142
- Acute Ischemic Stroke140
- Sarcopenia134
- Mild Cognitive Impairment129
- Cerebral Palsy120
- Pain Management116
- Migraine107
- Fibromyalgia104
Leading sponsors
- Beijing Tiantan Hospital125
- Assistance Publique - Hôpitaux de Paris110
- Riphah International University105
- Mayo Clinic98
- VA Office of Research and Development91
- Xuanwu Hospital, Beijing89
- Hospices Civils de Lyon77
- Johns Hopkins University70
- University of Minnesota63
- Washington University School of Medicine63
Where studies are running
- California662
- Massachusetts306
- New York296
- Florida272
- Texas267
- Maryland249
- Alabama206
- Arizona206
- Illinois181
- Pennsylvania177
Recruiting studies11,975 total
- NCT05614310Recruiting
Brain scan study to spot early Alzheimer’s
This study uses MRI brain scans and memory tests to help detect early Alzheimer’s disease. It compares people with Alzheimer’s (diagnosed by a clinician) with people without memory problems to see which scan and test results stand out.
AberdeenAges 18 years+ - NCT05848271Recruiting
Natural history study for people with HPDL gene changes
This study follows people who have an HPDL gene change to better understand how symptoms and health progress over time. It may help clinicians learn more about the condition and plan future treatments.
San Diego, CaliforniaAges Any age - NCT06221553RecruitingPhase 1
New CAR T-cell treatment for DIPG brain tumor
This trial tests a new type of immunotherapy called B7H3 IL-7Ra CAR T-cells for children with DIPG, a tough-to-treat brain tumor. The treatment is given directly into the fluid around the brain using a special catheter, and the goal is to see if it's safe and if it can help fight the tumor.
Bangkok, PathumwanAges 1–18 - NCT07251491RecruitingPhase 1/Phase 2
Psilocybin for depression after spinal cord injury
This trial tests whether psilocybin (a substance found in certain mushrooms) can help treat depression in people with a spinal cord injury. You would receive the study drug in a controlled setting, and your progress would be monitored closely.
The Bronx, New YorkAges 22 years+ - NCT07258069Recruiting
Glue injection for chronic subdural hematoma
This trial tests whether injecting a medical glue into a specific artery in the brain can safely treat a chronic subdural hematoma (a collection of blood on the brain's surface) or a recurrent subdural hematoma. This approach may offer a less invasive alternative to traditional surgery.
Fukuoka, Kitakyushu-cityAges 18 years+ - NCT07258212Recruiting
Safety and normal vision data study with Neos device
This study is testing a device called Neos to gather safety information and normal vision data. It includes both healthy volunteers and people with eye or brain conditions, helping researchers understand how vision and eye movements work.
Bern, Canton of BernAges 3 years+ - NCT07258290Recruiting
Freesolve Magnesium Scaffold for Heart Artery Blockages
This trial tests a new dissolvable magnesium scaffold to treat blockages in heart arteries. It is designed for people with stable heart pain or certain recent heart attacks, and it aims to open blocked arteries and then slowly dissolve over time.
Washington D.C., District of ColumbiaAges 18–80 - NCT07250750RecruitingPhase 1/Phase 2
IM-101 for generalized and ocular myasthenia gravis
This study tests a new medicine called IM-101 in people with myasthenia gravis (MG), a muscle weakness condition. It aims to see if it can safely help manage symptoms.
Altamonte Springs, FloridaAges 18–74 - NCT07252492Recruiting
Testing a new hearing device for people with hearing loss
This study tests a new hearing device called 'Audiocap' to see if it helps people with mild to moderate hearing loss hear better. It may be an option if you are getting your first hearing aid.
Lyon, FranceAges 18 years+ - NCT07252440RecruitingPhase 2
Testing an oral drug for early Alzheimer's disease
This study tests an oral tablet (TTYP01) for people with early Alzheimer's disease. It aims to see if the drug can slow memory loss. You must have a study partner who can support you throughout the trial.
Chongqing, Chongqing MunicipalityAges 55–85 - NCT07256925Recruiting
Malnutrition screening for clinic patients
This trial is testing a simple screening tool to identify malnutrition risk in adults visiting hospital clinics. Participating could help researchers find better ways to spot nutrition problems early and connect you with help.
Sarıçam, AdanaAges 18 years+ - NCT07251023RecruitingPhase 3
Testing a new drug for Alzheimer's dementia
This study tests whether a new drug called Latrepirdine (DMB-I) is safe and effective for people with mild to moderate Alzheimer's dementia. It may help slow cognitive decline when added to current treatment or used alone.
Kazan'Ages 60–90 - NCT07252895Recruiting
Testing the EXOPULSE Suit for walking in multiple sclerosis
This trial tests whether the EXOPULSE Suit can help people with multiple sclerosis walk better. You will try the suit and we will measure how it affects your walking over time.
BerckAges 18 years+ - NCT07249632RecruitingPhase 3
Study of Telitacicept for Eye Muscle Weakness from Myasthenia Gravis
This trial tests a new drug, telitacicept, for people with myasthenia gravis that only affects the eyes (ocular myasthenia gravis). The goal is to see if it can improve symptoms like droopy eyelids or double vision.
Beijing, Beijing MunicipalityAges 12–80 - NCT07254234Recruiting
Eye scans to detect Alzheimer's-related proteins
This study uses a special eye scan to look for abnormal protein deposits in the retina, which may be linked to Alzheimer's disease. It is for people who are generally healthy but have mild memory concerns or mild cognitive impairment.
Abu DhabiAges 55 years+ - NCT07250828Enrolling by invitation
BurstDR spinal cord stimulation for painful diabetic neuropathy
This trial tests a type of spinal cord stimulation called BurstDR to see if it can reduce pain from diabetic nerve damage. It may help people with diabetes who have ongoing leg pain that hasn't gotten better with standard pain medications.
Grand Island, NebraskaAges 19 years+ - NCT06731335RecruitingPhase 2
Psilocybin for chronic nerve pain that hasn't improved with other treatments
This study tests whether psilocybin (a compound found in certain mushrooms) can help reduce chronic nerve pain that has not responded well to standard medications. You will receive study treatment plus psychotherapy to see if it improves your pain.
Toronto, OntarioAges 18–65 - NCT06902415Recruiting
Using a computer analysis platform for brain blood vessel disease
This study uses a special computer platform to analyze DSA scan images from people with brain blood vessel diseases. It aims to better understand their condition and guide treatment decisions.
Beijing, Beijing MunicipalityAges 1–80 - NCT07250958Recruiting
Testing dome-only coiling for severe aneurysm bleeding
This trial tests a specific way of treating a brain aneurysm that has caused a severe bleed (subarachnoid hemorrhage). Instead of coiling the whole aneurysm, doctors will only coil the dome part. The goal is to see if this simpler approach helps patients who are very sick from the bleeding.
Louisville, KentuckyAges 18 years+ - NCT07256795Enrolling by invitation
ME/CFS after COVID-19 vs. before the pandemic
This study looks at how the brain's protective barrier and immune system work in people with ME/CFS, comparing those who got sick before the COVID-19 pandemic to those who developed ME/CFS after a COVID-19 infection. It aims to understand why some people have lasting brain fog, fatigue, and other neuropsychiatric symptoms.
Baltimore, MarylandAges 18–70 - NCT07256704Recruiting
Hypnosis and attention for neurological conditions
This study looks at whether hypnosis can help improve attention in people with conditions like stroke, traumatic brain injury, or multiple sclerosis. It may help if you have trouble concentrating or focusing.
LucerneAges 18 years+ - NCT07253870Recruiting
Nerve stimulation for subacute stroke recovery
This study compares two types of nerve stimulation (one on the ear, one on the neck) to see which helps upper limb movement better in people who had a stroke 3–6 months ago. It may help improve arm and hand function.
Lahore, Punjab ProvinceAges 45–70 - NCT07252310Enrolling by invitationPhase 4
Smartphone app to find best beta blocker dose for heart failure
This study uses a smartphone app to test how different beta blocker doses work best for you. It's for older adults with stable heart failure who want to fine-tune their treatment.
New York, New YorkAges 65 years+ - NCT07251140Recruiting
Swallowing study with a new microphone device
This study tests a new microphone device to see if it can help find swallowing problems in people who have had a stroke. If you are already scheduled for a swallowing test, you may be able to take part.
Atlanta, GeorgiaAges 40–85
Common questions
- How many brain & nervous system clinical trials are recruiting?
- Clin2 is tracking 11,975 recruiting neurology studies from the U.S. registry right now, out of 18,541 we cover in this area in total.
- What does “Brain & nervous system” cover here?
- Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We group each study into brain & nervous system based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a brain & nervous system trial near me?
- Use the search to filter brain & nervous system studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.