Neurology
Brain & nervous system clinical trials
Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We’re tracking 12,425 recruiting studies in this area right now.
By phase
- Not applicable9,762
- Phase 2784
- Phase 1574
- Phase 3535
- Phase 4342
- Phase 1/Phase 2305
- Phase 2/Phase 3123
Top conditions
- Stroke845
- Parkinson Disease426
- Multiple Sclerosis343
- Alzheimer Disease341
- Dementia226
- Ischemic Stroke200
- Epilepsy197
- Obstructive Sleep Apnea155
- Spinal Cord Injuries154
- Insomnia153
- Sarcopenia149
- Traumatic Brain Injury149
- Acute Ischemic Stroke139
- Cerebral Palsy131
- Mild Cognitive Impairment129
- Pain Management114
- Migraine112
- Amyotrophic Lateral Sclerosis108
Leading sponsors
- Beijing Tiantan Hospital133
- Riphah International University125
- Assistance Publique - Hôpitaux de Paris112
- Mayo Clinic99
- Xuanwu Hospital, Beijing94
- VA Office of Research and Development93
- Hospices Civils de Lyon79
- Johns Hopkins University70
- National Taiwan University Hospital70
- University of Minnesota64
Where studies are running
- California678
- Massachusetts300
- New York292
- Florida275
- Texas267
- Maryland245
- Arizona213
- Alabama211
- Illinois189
- Pennsylvania178
Recruiting studies12,423 total
- NCT05871606RecruitingPhase 1
Breathing nitric oxide during clot-removal for stroke
This Phase 1 study tests whether inhaled nitric oxide (a gas breathed through a ventilator) can improve outcomes in people having a specific kind of emergency stroke procedure to remove a clot from the brain. It focuses on patients who need general anesthesia for the clot-removal procedure and have imaging results that suggest salvageable brain tissue.
Charlotte, North CarolinaAges 18–80 - NCT05874739Recruiting
Track movement with a wearable sensor for 12 months
This study uses a wearable sensor to track how well people move over a year. It may help researchers understand mobility and how different movement conditions affect walking and daily function.
Newcastle upon TyneAges 18 years+ - NCT05875103Recruiting
Brain and language study using a word fluency task
This study looks at how thinking and language work in people with certain brain conditions, using a simple word-finding task and brain scans. It may help researchers better understand what brain changes are linked to different symptoms.
AmiensAges 18 years+ - NCT05877196Recruiting
Adaptive walking and fitness program for mild memory decline
This study tests an “adaptive” exercise plan that adjusts over time to help improve aerobic fitness and your body’s fitness response in people with mild memory problems or early Alzheimer’s. It may help you safely build the kind of fitness that supports brain health, while researchers monitor changes with fitness testing and blood work.
Phoenix, ArizonaAges 65 years+ - NCT05877391Recruiting
Collecting sexual and gender identity information in hospice
This study tests an approach to collect and use sexual orientation and gender identity (often called “SOGI”) information for people receiving hospice care. The goal is to help hospice teams better understand and support patients’ needs.
Aurora, ColoradoAges 18 years+ - NCT05877560Recruiting
Noninvasive brain stimulation for eye focusing trouble
This study tests a noninvasive brain stimulation treatment to improve symptoms of convergence insufficiency, a condition that makes near vision tasks like reading harder. You may be randomly assigned to the study treatment or a comparison condition.
Downers Grove, IllinoisAges 18–40 - NCT05877885Recruiting
Digital treatment for low motivation in older adults with depression
This study tests a digital therapy to improve apathy (feeling unmotivated or “checked out”) in people age 60+ who have depression. It also uses brain imaging (MRI) and questionnaires to see whether the treatment helps brain function linked to motivation.
Orlando, FloridaAges 60 years+ - NCT05877846Recruiting
Personalized care to improve physical function in older adults
This study looks at precision (personalized) approaches to help older adults improve physical function. It may include giving a specific supplement depending on lab results, and it requires regular study visits and ability to complete procedures.
Chapel Hill, North CarolinaAges 65–85 - NCT05878223Recruiting
Testing different shockwave doses for ankle stiffness after stroke
This study compares different doses of shockwave treatment to reduce ankle muscle tightness (spasticity) after stroke. If you have persistent ankle stiffness and can safely receive the treatment, your results may help find the best dose for symptom relief.
HsinchuAges 20 years+ - NCT05881031Recruiting
Home breathing support for medically complex children
This trial studies whether starting a noninvasive breathing machine (given without a tube in the airway) at home works well and is tolerated in children with medical complexity. It may help improve comfort and safety when new breathing support is prescribed.
Toronto, OntarioAges 5 years–17.9 years - NCT05881239Recruiting
Remote smell tests to track early Alzheimer’s health changes
This trial uses remote, at-home (or remote) smell-based testing to help researchers assess health in people with preclinical Alzheimer’s disease and in control participants. It may help by showing how well smell-related changes can signal disease status over time.
Boston, MassachusettsAges 18–100 - NCT05883969Recruiting
Family play program for infants at high risk for cerebral palsy
This trial tests an early, family-centered play-based intervention for infants who have a high risk of developing cerebral palsy. The goal is to help support early movement and development as soon as possible.
AalborgAges 3 months–1 year - NCT05884138Recruiting
Amino acid supplement and exercise for people on dialysis
This trial studies whether taking essential amino acids along with exercise can improve muscle function in people receiving hemodialysis. It may help you build or maintain strength and mobility.
Daejeon, South KoreaAges 20–80 - NCT05884762Recruiting
Brain training rehab for arm recovery after a recent stroke
This trial tests an upper-limb (arm/hand) rehabilitation program guided by brain activity signals, started soon after a stroke. It may help people with early incomplete arm recovery improve hand and arm function.
RennesAges 18–80 - NCT05884944Recruiting
Osteopathic massage study for leg muscle in Parkinson’s disease
This trial studies whether osteopathic manipulative medicine (gentle hands-on treatment) can change how leg muscles work in people with Parkinson’s disease. It may help with leg pain, cramping, or walking problems caused by Parkinson’s.
Old Westbury, New YorkAges 18 years+ - NCT05885295Recruiting
Testing thinking and memory after stroke using cognitive exams
This study looks at how thinking and memory change after a stroke using short cognitive tests. It may help researchers better understand which brain changes affect thinking, and how to measure them accurately.
LondonAges 18 years+ - NCT05885529Recruiting
Blood and CT tests after a concussion to track brain injury
This study checks whether two blood proteins (GFAP and UCH-L1) can help identify which brain spots are linked to a significant head injury after a concussion. You may be able to help by providing a blood sample and getting a CT scan as part of usual care, so doctors can better sort out injury risk.
AngersAges 18 years+ - NCT05885932Recruiting
Stent treatment versus medicines for blocked neck artery
This study compares a drug-coated stent placed in a neck (vertebral) artery versus best medical treatment with medicines and risk-factor control. It aims to reduce problems caused by a badly narrowed artery after recent stroke-like symptoms.
BeijingAges 18 years+ - NCT05886114Recruiting
Lifestyle program to help older adults at risk of memory decline
This trial tests a multi-part lifestyle program to help older adults who may be starting to decline in thinking and memory. It may help slow cognitive decline by combining lifestyle changes over 24 months.
Hangzhou, ZhejiangAges 60–80 - NCT05886725Recruiting
At-home walking test to help recovery after major surgery
This study looks at how a simple at-home walking pattern test, done before and after major surgery, relates to how older adults recover. It may help doctors better understand recovery and possibly tailor support after surgery.
Chicago, IllinoisAges 60 years+ - NCT05887440Recruiting
Isokinetic strength training for knee control after stroke
This trial studies whether a special strength-training program that uses an “isokinetic” machine can improve walking and knee control in people after stroke. It is for people who have noticeable knee movement during walking and can safely take part in rehab.
RennesAges 18–75 - NCT05887674Recruiting
Non-drug memory program for early Alzheimer’s and memory loss
This trial studies a non-medication (non-drug) program to improve memory and daily thinking in people with mild cognitive impairment or mild Alzheimer’s disease. It may help by supporting brain function and monitoring symptoms over time.
Shanghai, Shanghai MunicipalityAges 60–90 - NCT05888441Recruiting
Walking obstacle testing in people with and without vision trouble
This trial studies how people negotiate obstacles while walking, comparing those with normal vision and those with vision impairment. It may help researchers better understand balance and safety needs for walking in everyday settings.
Bloomington, IndianaAges 18 years+ - NCT05888688Recruiting
Studying muscle loss in people with heart failure or diabetes
This study looks at sarcopenia, which is age-related loss of muscle, in people with certain types of heart failure or in people with stable type 2 diabetes but no symptoms. The goal is to better understand muscle changes and what might help people stay stronger.
Leicester, LeicestershireAges 18 years+
Common questions
- How many brain & nervous system clinical trials are recruiting?
- Clin2 is tracking 12,425 recruiting neurology studies from the U.S. registry right now, out of 19,436 we cover in this area in total.
- What does “Brain & nervous system” cover here?
- Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We group each study into brain & nervous system based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a brain & nervous system trial near me?
- Use the search to filter brain & nervous system studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.