Neurology
Brain & nervous system clinical trials
Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We’re tracking 11,975 recruiting studies in this area right now.
By phase
- Not applicable9,368
- Phase 2765
- Phase 1561
- Phase 3516
- Phase 4338
- Phase 1/Phase 2301
- Phase 2/Phase 3126
Top conditions
- Stroke799
- Parkinson Disease395
- Alzheimer Disease339
- Multiple Sclerosis330
- Dementia227
- Epilepsy194
- Ischemic Stroke190
- Insomnia159
- Traumatic Brain Injury151
- Obstructive Sleep Apnea142
- Spinal Cord Injuries142
- Acute Ischemic Stroke140
- Sarcopenia134
- Mild Cognitive Impairment129
- Cerebral Palsy120
- Pain Management116
- Migraine107
- Fibromyalgia104
Leading sponsors
- Beijing Tiantan Hospital125
- Assistance Publique - Hôpitaux de Paris110
- Riphah International University105
- Mayo Clinic98
- VA Office of Research and Development91
- Xuanwu Hospital, Beijing89
- Hospices Civils de Lyon77
- Johns Hopkins University70
- University of Minnesota63
- Washington University School of Medicine63
Where studies are running
- California662
- Massachusetts306
- New York296
- Florida272
- Texas267
- Maryland249
- Alabama206
- Arizona206
- Illinois181
- Pennsylvania177
Recruiting studies11,975 total
- NCT06260072RecruitingPhase 2
Magnesium and Riboflavin for Post-Concussion Headaches
This trial tests if taking magnesium and riboflavin (vitamin B2) can help reduce headaches after a concussion. It is for University of Virginia students who have had a concussion within the past 3 days and can swallow pills.
Charlottesville, VirginiaAges 18–40 - NCT06068361Recruiting
Better diagnosis of Lewy body dementia
This study uses a combination of tests to improve diagnosis of dementia with Lewy bodies compared to Alzheimer's disease and healthy aging. You may help doctors identify the right diagnosis more accurately.
Paris, FranceAges 55–85 - NCT06899048Recruiting
Does a risk score predict muscle recovery after surgery?
This study looks at whether a simple risk score can predict how long it takes for muscles to fully recover after surgery. It may help doctors decide when it is safe to wake you up fully.
AsyutAges 18–65 - NCT06540859Recruiting
Spinal cord stimulation for recovery after spinal cord injury
This study tests whether a spinal cord stimulator (a device that sends mild electrical pulses to the spine) can help improve bladder, bowel, and other automatic body functions during inpatient rehab after a recent spinal cord injury. It's for people who have a non-worsening injury at or above the T6 level and are within 4 months of their injury.
Seattle, WashingtonAges 21–65 - NCT06471634Recruiting
Improving sleep and reducing sitting time in type 2 diabetes
This study tests whether a program to improve sleep and reduce sitting time can help people with type 2 diabetes. It combines cognitive behavioral therapy for insomnia with tips to move more during the day.
Leicester, LeicestershireAges 18–75 - NCT06754995Recruiting
Testing a new nerve stimulation method for surgery
This trial tests a special nerve stimulation technique (100 Hz tetanic stimulation) to see if it can help monitor muscle function during anesthesia. It might help doctors make sure patients are properly relaxed during surgery.
Debrecen, Hajdú-BiharAges 18–65 - NCT06866028Recruiting
Brain training to improve emotion regulation using fNIRS feedback
This trial uses a brain imaging technique called fNIRS (a safe, non-invasive headband) to give you real-time feedback on your brain activity. The goal is to help you learn to improve your emotion regulation. It may be helpful if you have no major mental health conditions and want to try a new way to manage emotions.
Hong KongAges 18–30 - NCT06898671Recruiting
Language Skills in Adults With and Without DLD
This study looks at how language skills change over time in adults ages 30–35, by comparing people with Developmental Language Disorder (a lifelong difficulty with language) to those with typical language skills. Participants must have been in an earlier University of Iowa study to join.
Iowa City, IowaAges 30–35 - NCT06897553Recruiting
ACT for Better Mental Health with Neurologic Illness
This study tests a type of talk therapy (ACT) to help people with neurological conditions like Parkinson’s, MS, or epilepsy feel better emotionally. It's for those who are struggling with depression, anxiety, or stress and are ready to work on their mental health.
BielefeldAges 18 years+ - NCT05867641Recruiting
Immersive VR to help dementia caregivers and improve daily life
This study tests whether immersive virtual reality (VR) can help people with dementia feel better and reduce troubling behaviors, while also giving caregivers a break. If you and a family caregiver qualify, you may use VR as part of an at-home support program.
Oakville, OntarioAges 65 years+ - NCT05899582Recruiting
Heart-bypass–like brain surgery for artery blockage patients
This trial studies whether a special bypass surgery can improve symptoms in people with a long-term (chronic) blockage of the middle brain artery. It aims to improve brain blood flow and reduce future stroke risk in the right patients.
BeijingAges 18–65 - NCT04102930Recruiting
Study of immune and genetic features in GCA and PMR
This study looks at immune system and genetic (inherited) differences in people diagnosed with giant cell arteritis or polymyalgia rheumatica. It aims to improve understanding of why these conditions happen and how they vary between people.
Canterbury, KentAges 50 years+ - NCT06410495Recruiting
Digital family sleep program for children with ODD
This study tests a digital program for families to help children with Oppositional Defiant Disorder (ODD) and their parents get better sleep. The program provides tools and support to improve sleep habits for both the child and the parent.
Tampa, FloridaAges 8–17 - NCT06350292Recruiting
Sleep help for children with ODD and insomnia
This study tests a sleep program for children ages 8-12 who have Oppositional Defiant Disorder (ODD) and trouble sleeping. The program aims to improve sleep and reduce daytime problems like mood swings and trouble focusing.
Tampa, FloridaAges 8–12 - NCT06016309Recruiting
Understanding Thinking, Energy, Mood, and Behavior in MS
This study looks at how multiple sclerosis affects thinking, energy, mood, and behavior. It uses simple tests and questionnaires to understand your unique profile, which may help tailor future care.
Groningen, Provincie GroningenAges 18–70 - NCT06715007Recruiting
Study on blood thinners and artery health for small vessel stroke
This study tests whether a combination of antiplatelet drugs and artery-stabilizing medication can improve recovery after a small stroke caused by damage to tiny blood vessels in the brain. It may help prevent further strokes and support healing.
Nanjing, JiangsuAges 30–79 - NCT06899399Recruiting
Stent study for asymptomatic carotid artery blockage
This trial tests a stent procedure to open a severely blocked carotid artery in people who have not had a stroke or mini-stroke from that blockage recently. It aims to see if the procedure is safe and effective for preventing future strokes.
BeijingAges 40–80 - NCT06900101Recruiting
Monitoring study in brain injury intensive care
This study uses a special monitoring system to closely watch patients in the neurologic intensive care unit. It may help doctors better understand and treat brain injuries.
France, BronAges 18–90 - NCT03594344Recruiting
Extra hyperbaric oxygen after leg amputation wounds heal
This study tests whether giving extra treatments with hyperbaric (pressure) oxygen after a leg amputation can improve healing or recovery. It’s meant for people whose amputation happened due to long-lasting infection or poor blood flow and who can attend follow-up visits.
OsloAges 18–90 - NCT06899841RecruitingPhase 2/Phase 3
Dexmedetomidine in a nerve block for kidney stone surgery
This study tests whether adding a medicine called dexmedetomidine to a nerve block (an injection near the spine) can improve pain relief after kidney stone surgery. It is for people who are generally healthy and scheduled for a kidney stone procedure.
Asyut, Assiut GovernorateAges 18–70 - NCT02964637Recruiting
Tests to help diagnose frontotemporal dementia
This study looks at testing (including brain scans) to figure out what type of frontotemporal dementia or related language/speech condition a person has. It may help by making diagnoses more accurate, which can guide better care.
Toronto, OntarioAges 18–90 - NCT05327933Recruiting
Preventing chronic bleeding from the brain’s covering after surgery
This trial looks at whether a procedure called middle meningeal artery embolization can help stop chronic subdural hematoma (slow bleeding/collection under the brain covering) from coming back after your first surgery. It studies an added endovascular treatment right after your operation to reduce recurrence.
Berlin, State of BerlinAges 18 years+ - NCT05218278Recruiting
Nerve and brain signals after out-of-hospital cardiac arrest
This study looks at measurements taken after someone survives an out-of-hospital cardiac arrest to see if the results can predict outcomes. It may help doctors understand which patients are likely to do better and guide care in the ICU.
MariborAges 18 years+ - NCT05460507RecruitingPhase 1
Re-treating brain tumor with radioactive liposome after prior dose
This Phase 1 trial tests whether a radioactive treatment delivered in tiny fat “packets” is safe and tolerable when given again to people whose glioma (brain tumor) came back after a previous similar treatment. It also looks at how well this re-treatment works in carefully selected patients.
San Antonio, TexasAges 18 years+
Common questions
- How many brain & nervous system clinical trials are recruiting?
- Clin2 is tracking 11,975 recruiting neurology studies from the U.S. registry right now, out of 18,541 we cover in this area in total.
- What does “Brain & nervous system” cover here?
- Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We group each study into brain & nervous system based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a brain & nervous system trial near me?
- Use the search to filter brain & nervous system studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.