Neurology
Brain & nervous system clinical trials
Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We’re tracking 12,425 recruiting studies in this area right now.
By phase
- Not applicable9,762
- Phase 2784
- Phase 1574
- Phase 3535
- Phase 4342
- Phase 1/Phase 2305
- Phase 2/Phase 3123
Top conditions
- Stroke845
- Parkinson Disease426
- Multiple Sclerosis343
- Alzheimer Disease341
- Dementia226
- Ischemic Stroke200
- Epilepsy197
- Obstructive Sleep Apnea155
- Spinal Cord Injuries154
- Insomnia153
- Sarcopenia149
- Traumatic Brain Injury149
- Acute Ischemic Stroke139
- Cerebral Palsy131
- Mild Cognitive Impairment129
- Pain Management114
- Migraine112
- Amyotrophic Lateral Sclerosis108
Leading sponsors
- Beijing Tiantan Hospital133
- Riphah International University125
- Assistance Publique - Hôpitaux de Paris112
- Mayo Clinic99
- Xuanwu Hospital, Beijing94
- VA Office of Research and Development93
- Hospices Civils de Lyon79
- Johns Hopkins University70
- National Taiwan University Hospital70
- University of Minnesota64
Where studies are running
- California678
- Massachusetts300
- New York292
- Florida275
- Texas267
- Maryland245
- Arizona213
- Alabama211
- Illinois189
- Pennsylvania178
Recruiting studies12,423 total
- NCT05900414Recruiting
Help choosing blood thinners to prevent stroke in AF
This trial tests a web-based decision aid that helps people with atrial fibrillation (AF) decide about stroke-prevention treatment, such as blood thinners. It may help you feel more confident and make safer choices by showing options at the right time after diagnosis.
Calgary, AlbertaAges 18 years+ - NCT05901259Recruiting
Tracking routine outcomes using a mobility suit database
This trial sets up a database to follow routine health and mobility outcomes over time. You may be included if you have certain neurological conditions and can safely use the EXOPULSE suit.
Bergshamra, Stockholm CountyAges 2 years+ - NCT05901493Recruiting
Memory learning task study for adults with language difficulty
This study checks how well adults remember and use newly learned language information over time. It compares people with developmental language disorder to people without it to understand what may affect long-term learning.
Newark, DelawareAges 18–55 - NCT05901675Recruiting
Weight loss and exercise after stroke in walking recovery
This trial studies whether a weight-loss plan combined with exercise can improve walking and leg movement after stroke. It may help if you have ongoing leg weakness but can still walk without devices for testing.
Charleston, South CarolinaAges 35–85 - NCT05902195Recruiting
Improve work ability for young adults after stroke
This study aims to help young adults who have had a stroke improve their ability to work. It may help people get back to work and manage daily function after stroke.
Hong KongAges 18 years+ - NCT05902351Recruiting
Study of the natural course of Charcot-Marie-Tooth disease
This study looks at how Charcot-Marie-Tooth disease (CMT) or related inherited nerve conditions change over time. It may help researchers better understand what to expect and guide future treatments.
New York, New YorkAges Any age - NCT05902910Recruiting
Robot therapy to improve arm movement after long-term stroke
This trial tests whether a therapy robot (the Luna EMG rehabilitation robot) can improve arm movement and be acceptable to use for people with chronic stroke. It focuses on helping the arm recover function over time and seeing how well patients tolerate the approach.
BrestAges 18 years+ - NCT05903027Recruiting
Testing gepant migraine treatment for better side effects
This trial studies how well a “gepant” medicine works for different types of migraine and how tolerable it is. It may help if you have frequent migraines and you can keep a headache diary as the study asks.
FlorenceAges 18 years+ - NCT05903235Recruiting
VR and mirror therapy for arm recovery after stroke
This trial tests a mix of virtual reality (VR) and mirror therapy to help improve arm movement after a stroke. You may be asked to use the technology and give feedback, and the study may compare it with other care approaches to see if it helps more.
Taoyuan CityAges 20–80 - NCT05903560Recruiting
Arm versus leg access for clot removal in basilar stroke
This trial compares doing a clot-removal procedure through the arm artery versus the leg artery for an emergency stroke caused by a blocked basilar artery. It aims to see which access route is safer and more effective for restoring blood flow when time is critical.
Nanjing, JiangsuAges 18 years+ - NCT05903859RecruitingPhase 3
Study to improve fertility in men after spinal cord injury
This phase 3 study tests a treatment to improve reproductive function (fertility-related measures) in men who have had a traumatic spinal cord injury. If you may be eligible, it could help researchers see whether the treatment improves reproductive outcomes for men with spinal cord injury.
Miami, FloridaAges 18 years+ - NCT05903898Recruiting
AI to improve stroke care after hospital admission
This trial uses artificial intelligence (computer tools that help analyze information) to improve stroke care for people admitted quickly after symptoms start. It may help hospitals make faster or better care decisions, based on patient details and follow-up results.
TromsøAges 18 years+ - NCT05904301Recruiting
Registry for autoimmune and autoinflammatory disease patients
This study builds a nationwide list (registry) of people with certain autoimmune or inflammation-related illnesses. It helps researchers understand these diseases better over time, which can guide future care.
YerevanAges Any age - NCT05905419Recruiting
Brain scan study of opioid effects in women with pain
This study uses brain imaging (MRI) to understand how opioid medications may affect the brain in women. People with chronic pain who take opioids (or do not) and healthy women without chronic pain may be invited to participate.
Durham, North CarolinaAges 18 years+ - NCT05906056Recruiting
CPM therapy vs bone overgrowth in hip or knee
This study compares continuous passive motion (a machine that gently moves a joint without you moving it) versus the body’s tendency to form extra bone called heterotopic ossification. It aims to see whether CPM can affect how and how much bone overgrowth develops after neurologic injuries like stroke, brain injury, or spinal cord injury.
Ioannina, EpirusAges 15–70 - NCT05907005Recruiting
Text-message mental health support for stroke family caregivers
This study tests whether instant-message support can reduce stress and depression symptoms for family caregivers of people having their first stroke. It may help you cope better while your loved one is in the hospital and during early recovery.
Hong KongAges 18 years+ - NCT05906992RecruitingPhase 3
Testing CT-P53 versus Ocrevus for relapsing MS
This Phase 3 study compares CT-P53 with Ocrevus in people with relapsing-remitting multiple sclerosis (MS). It aims to see how well each treatment controls MS activity and to compare safety and study drug effects.
PoznanAges 18–55 - NCT05907031Recruiting
Brain stimulation to improve language after left-stroke aphasia
This trial studies a specific brain-stimulation method to help improve speech and language problems (aphasia) after an ischemic stroke. You may qualify if your stroke affected the left side of the brain and your language testing shows moderate language difficulty.
Fuzhou, FujianAges 35–75 - NCT05907239Recruiting
Shock wave therapy for jaw muscle pain
This trial tests whether focused shock wave treatment can reduce chronic jaw pain caused by jaw muscle problems. You might qualify if you have moderate to severe temporomandibular (jaw) pain for at least 3 months.
São Paulo, São PauloAges 18 years+ - NCT05907694Recruiting
Treatment of stroke from PFO, with or without closure
This study looks at whether treating a history of “cryptogenic” stroke (stroke with no clear cause) using a patent foramen ovale (PFO) closure, plus medical therapy, is better than medical therapy alone. It focuses on people over 60 with a heart shunt seen on an ultrasound of the heart.
Québec, QuebecAges 18 years+ - NCT05907837Recruiting
Early check and support for infants at risk for cerebral palsy
This study looks at early detection and early support for babies who are at higher risk of cerebral palsy and developmental delays. It may help by finding concerns sooner and starting help earlier.
CorkAges Up to 9 months - NCT05908123Recruiting
Study of stuttering in children and adults
This study looks at how stuttering shows up, how severe it is, and possible ways to assess and treat it. It may help by giving you a chance to work with speech specialists and get a structured evaluation.
Austin, TexasAges 2–85 - NCT05908149Recruiting
Gait analysis with a shoe insole splint after stroke
This study checks how a special shoe insole splint affects walking patterns in people recovering from a stroke. It’s looking at gait (walking) measurements to see whether the splint can help safely during physical therapy.
IoanninaAges 18–70 - NCT05908695RecruitingPhase 4
GV-971 treatment for mild to moderate Alzheimer’s disease
This Phase 4 trial tests whether a medicine called sodium oligomannate (GV-971) is safe and effective for people with mild to moderate Alzheimer’s disease. It may help slow or improve memory and thinking symptoms while carefully tracking side effects.
Huainan, AnhuiAges 50–85
Common questions
- How many brain & nervous system clinical trials are recruiting?
- Clin2 is tracking 12,425 recruiting neurology studies from the U.S. registry right now, out of 19,436 we cover in this area in total.
- What does “Brain & nervous system” cover here?
- Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We group each study into brain & nervous system based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a brain & nervous system trial near me?
- Use the search to filter brain & nervous system studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.