Neurology
Brain & nervous system clinical trials
Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We’re tracking 12,432 recruiting studies in this area right now.
By phase
- Not applicable9,770
- Phase 2785
- Phase 1574
- Phase 3537
- Phase 4342
- Phase 1/Phase 2303
- Phase 2/Phase 3121
Top conditions
- Stroke846
- Parkinson Disease424
- Multiple Sclerosis343
- Alzheimer Disease340
- Dementia226
- Ischemic Stroke200
- Epilepsy196
- Obstructive Sleep Apnea155
- Insomnia153
- Spinal Cord Injuries153
- Sarcopenia149
- Traumatic Brain Injury149
- Acute Ischemic Stroke141
- Cerebral Palsy131
- Mild Cognitive Impairment129
- Pain Management114
- Migraine112
- Amyotrophic Lateral Sclerosis107
Leading sponsors
- Beijing Tiantan Hospital134
- Riphah International University126
- Assistance Publique - Hôpitaux de Paris112
- Mayo Clinic99
- Xuanwu Hospital, Beijing94
- VA Office of Research and Development93
- Hospices Civils de Lyon79
- Johns Hopkins University70
- National Taiwan University Hospital70
- University of Minnesota64
Where studies are running
- California674
- Massachusetts300
- New York291
- Florida274
- Texas267
- Maryland245
- Arizona214
- Alabama209
- Illinois190
- Pennsylvania177
Recruiting studies12,430 total
- NCT06419959Recruiting
NightWare watch for better sleep and heart health in veterans with PTSD
This study tests if a special watch (NightWare) can help veterans with PTSD who have nightmares sleep better and improve heart health. The watch vibrates gently during nightmares to reduce them without waking you up.
Aurora, ColoradoAges 22–88 - NCT06420141Recruiting
Nerve pain after ankle fracture surgery
This study looks at why some people develop nerve pain (neuropathic pain) after breaking their ankle and having surgery. If you have an ankle fracture that needs surgery, you may be able to join and help researchers understand this type of pain better.
Indianapolis, IndianaAges 18–85 - NCT06420271Recruiting
Cerebellar stimulation for ataxia symptoms
This trial tests a brain stimulation technique (tACS-iTBS) on the cerebellum to see if it can improve coordination and movement problems caused by ataxia. It might help if you have a stable medication routine and can follow instructions.
Rome, LazioAges 8–80 - NCT06420778Recruiting
Acupuncture for head and face nerve pain after shingles
This trial tests whether a gentle form of acupuncture (superficial needling with electroacupuncture) can relieve long-lasting nerve pain after shingles on the head and face. It may help if you have had head or face shingles and the pain has continued for a month or more.
Hangzhou, ZhejiangAges 50–80 - NCT06421350Recruiting
Closed-loop spinal cord stimulation for complex regional pain syndrome
This trial tests a new type of spinal cord stimulator that automatically adjusts to your pain signals. It may help people with complex regional pain syndrome (CRPS) who have not tried this kind of therapy before.
La Jolla, CaliforniaAges 18 years+ - NCT06421831RecruitingPhase 1/Phase 2
Gene therapy trial for spinal muscular atrophy type 3
This trial is testing a one-time gene therapy drug for people with SMA type 3. The goal is to see if it can safely improve muscle function and strength.
Beijing, Beijing MunicipalityAges 2 years+ - NCT06422442Recruiting
Information processing in adults who stutter
This study looks at how adults who stutter process information and react to different situations. It may help researchers understand the thinking patterns linked to stuttering.
Memphis, TennesseeAges 18–65 - NCT06422741Recruiting
Grape seed extract for cholesterol in night shift workers
This study tests whether a grape seed extract supplement can help lower LDL (bad) cholesterol in people who work rotating night shifts. It is looking for healthy adults with moderately high cholesterol who are not taking cholesterol medicine.
Reus, TarragonaAges 18 years+ - NCT06422923RecruitingPhase 1/Phase 2
Cell therapy for hard-to-treat epilepsy starting in both temporal lobes
This trial tests a new cell therapy (NRTX-1001) for people with epilepsy that starts in both sides of the brain's temporal lobes and doesn't get better with medication. It aims to reduce or stop seizures.
Little Rock, ArkansasAges 18–75 - NCT06423547Recruiting
Predicting confusion after surgery in older adults
This study looks at older patients (65 and older) who have had surgery and anesthesia. It aims to find who is at risk for confusion (delirium) and memory problems afterward. The goal is to help doctors prevent these issues.
BeijingAges 65–100 - NCT06423664Recruiting
Study on child development after cannabis use in pregnancy
This study looks at how cannabis (marijuana) use during pregnancy might affect a child's development. If you used cannabis while pregnant and gave birth to a healthy baby at full term, you and your child may be able to join.
Albuquerque, New MexicoAges Up to 1 week - NCT06424158Recruiting
Massage therapy after upper or lower back surgery
This study tests if massage therapy can help children recover after their first back surgery (thoracic or lumbar fusion). It's for kids who can talk and don't have certain health problems like chronic pain or bleeding disorders.
Fort Worth, TexasAges 7–19 - NCT06424743Recruiting
Strength training volume for women with fibromyalgia
This study tests whether different amounts of strength training (resistance exercise) help women with fibromyalgia feel better. It compares three different workout volumes to see which one women prefer and which works best for their symptoms.
Natal, Rio Grande do NorteAges 18–65 - NCT06425029Recruiting
Music app therapy for hard-to-control epilepsy with RNS
This study is testing a music-based app that you can use at home to help treat seizures. It is for adults with focal epilepsy who already have an RNS device and whose seizures are not controlled by medication.
Worcester, MassachusettsAges 18 years+ - NCT06425380Recruiting
Resistant potato starch for liver cirrhosis and confusion
This study is testing whether a special type of starch (resistant potato starch) can help people with cirrhosis who have had episodes of confusion from liver problems. It may help by changing the bacteria in your gut, which could reduce the risk of future confusion episodes.
Rochester, MinnesotaAges 18–99 - NCT06425731Recruiting
Dance and energy in Parkinson's disease
This study looks at how dancing affects energy use in people with Parkinson's. If you already take Dance for PD® classes and have mild to moderate Parkinson's, researchers want to see how your body responds during a dance class.
Boston, MassachusettsAges 18–85 - NCT06426316Recruiting
Immune cells and migraines study
This study looks at how certain immune cells and inflammatory chemicals relate to migraines. If you have migraines or an autoimmune condition (like lupus, rheumatoid arthritis, or Crohn's disease), you may be able to participate. The goal is to understand what causes migraines.
Clermont-Ferrand, AURAAges 18–50 - NCT06426498Recruiting
Ultrasound and temporary blind spot study
This study tests whether a focused ultrasound technique can create a temporary blind spot in the vision. Researchers hope this will help them find the right ultrasound dose for each person, with the goal of treating certain brain conditions.
Charleston, South CarolinaAges 18–70 - NCT06426615Recruiting
Understanding brain signals in unresponsive states after injury
This study looks at brain activity in people who are unresponsive after a brain injury. It uses advanced brain scans to see if there are hidden signs of consciousness, which could help doctors better understand and care for these patients.
Leuven, Vlaams-BrabantAges 18 years+ - NCT06426953Recruiting
Proteins in blood to predict confusion after surgery in older diabetics
This study looks at proteins in your blood (TGF-β and INS-PI3K-AKT) to see if they can predict confusion after surgery (postoperative delirium) in older adults with diabetes. It may help doctors identify who is at higher risk.
Duyun, GuizhouAges 65 years+ - NCT06427265Recruiting
Recovery after ICU: a long-term study
This study follows people after they leave the ICU to see how they recover over time. It uses computer programs to find patterns and create early warning tools to help doctors spot problems sooner.
Guiyang, GuizhouAges 18–100 - NCT06427304Recruiting
Heart scan study for amyloid protein in older adults
This trial is testing older adults with heart failure to see if a heart condition called cardiac amyloidosis (a buildup of abnormal protein in the heart) is present. If you are 80 or older, have been in the hospital for heart failure in the past year, and have a thickened heart wall, you may be able to join.
Paris, IIe-de-FranceAges 80 years+ - NCT06428006RecruitingPhase 2
Sleep therapy for insomnia in multiple sclerosis
This study tests whether a talking therapy (cognitive behavioral therapy for insomnia) can help people with multiple sclerosis who have trouble sleeping. It is done online, so you can join from home.
Kansas City, KansasAges 18–65 - NCT06428032Recruiting
Habit training for children with bilateral cerebral palsy
This trial tests a therapy called HABIT-ILE to see if it helps children with bilateral cerebral palsy improve hand use and brain function. It may be a good fit if your child can follow instructions and has certain levels of hand and movement ability.
Santiago, Santiago MetropolitanAges 8–18
Common questions
- How many brain & nervous system clinical trials are recruiting?
- Clin2 is tracking 12,432 recruiting neurology studies from the U.S. registry right now, out of 19,532 we cover in this area in total.
- What does “Brain & nervous system” cover here?
- Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We group each study into brain & nervous system based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a brain & nervous system trial near me?
- Use the search to filter brain & nervous system studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.