Neurology
Brain & nervous system clinical trials
Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We’re tracking 12,432 recruiting studies in this area right now.
By phase
- Not applicable9,770
- Phase 2785
- Phase 1574
- Phase 3537
- Phase 4342
- Phase 1/Phase 2303
- Phase 2/Phase 3121
Top conditions
- Stroke846
- Parkinson Disease424
- Multiple Sclerosis343
- Alzheimer Disease340
- Dementia226
- Ischemic Stroke200
- Epilepsy196
- Obstructive Sleep Apnea155
- Insomnia153
- Spinal Cord Injuries153
- Sarcopenia149
- Traumatic Brain Injury149
- Acute Ischemic Stroke141
- Cerebral Palsy131
- Mild Cognitive Impairment129
- Pain Management114
- Migraine112
- Amyotrophic Lateral Sclerosis107
Leading sponsors
- Beijing Tiantan Hospital134
- Riphah International University126
- Assistance Publique - Hôpitaux de Paris112
- Mayo Clinic99
- Xuanwu Hospital, Beijing94
- VA Office of Research and Development93
- Hospices Civils de Lyon79
- Johns Hopkins University70
- National Taiwan University Hospital70
- University of Minnesota64
Where studies are running
- California674
- Massachusetts300
- New York291
- Florida274
- Texas267
- Maryland245
- Arizona214
- Alabama209
- Illinois190
- Pennsylvania177
Recruiting studies12,430 total
- NCT06428734Recruiting
Outcomes study for normal pressure hydrocephalus
This study follows people with idiopathic normal pressure hydrocephalus (iNPH) to track their health outcomes over time. It helps doctors understand how the condition naturally progresses without surgery.
Beijing, Beijing MunicipalityAges 18–80 - NCT06429280Recruiting
Lazy Eye Treatment Registry for Luminopia Users
This registry collects information from people with lazy eye who have used Luminopia treatment for at least 12 weeks. It helps researchers learn more about how the treatment works in real life.
San Ramon, CaliforniaAges Any age - NCT06429501RecruitingPhase 2
Numbing medicine for facial fracture surgery
This study tests numbing medicine (local anesthetic) given during surgery for broken facial bones, like the jaw or cheekbones. The goal is to see how well it works and if it helps recovery.
St Louis, MissouriAges 18 years+ - NCT06429332RecruitingPhase 4
Care bundle study for brain bleed on CT scan
This trial is testing a set of standard care steps (a 'care bundle') for people who have a sudden brain bleed (intracerebral hemorrhage) that shows up on a CT scan. It aims to see if this bundle improves recovery and outcomes.
Oklahoma City, OklahomaAges 18 years+ - NCT06429735Recruiting
Robot-implanted brain-computer interface for severe paralysis
This trial tests a brain-computer interface (a device that lets you control a computer with your thoughts) that is implanted by a robot. It is for people with severe paralysis who may benefit from a new way to communicate or control devices.
Phoenix, ArizonaAges 22–75 - NCT06429774Recruiting
Comparing hospital treatments for traumatic brain injury
This study compares how well different hospital teams work together to treat people with traumatic brain injury. It aims to find the best care approach to help patients recover.
Beijing, Beijing MunicipalityAges 1–89 - NCT06430385RecruitingPhase 1/Phase 2
Study of ION440 for MECP2 Duplication Syndrome
This trial tests an experimental medicine called ION440 for people with MECP2 Duplication Syndrome. The medicine is given as an injection into the spinal fluid, and the study aims to check its safety and how well it works.
San Diego, CaliforniaAges 2–65 - NCT06430333RecruitingPhase 2
Sleep therapy to prevent depression in pregnancy
This study tests whether a sleep-focused therapy can help prevent depression in pregnant people who have insomnia. If you are 14–31 weeks pregnant and have trouble sleeping, this trial offers a program to improve your sleep and lower your risk of depression.
Novi, MichiganAges 18 years+ - NCT06430359Recruiting
How urine copper changes over 24 hours in Wilson disease
This study looks at how copper levels in urine change throughout the day and night in people with Wilson disease. If you take part, you will collect all your urine for 24 hours so researchers can measure copper at different times.
Bron, RhoneAges 6–70 - NCT06430632Recruiting
Early robotic walking training after stroke
This trial tests whether early, robot-assisted walking training can help people recovering from a stroke improve their ability to walk. It uses a wearable robotic exoskeleton to support your body and guide your legs during practice.
Dallas, TexasAges 18–85 - NCT06431685RecruitingPhase 1
Brain radiation, immunotherapy, and chemo for lung cancer spread
This trial tests a combination of low-dose radiation to the whole brain, immunotherapy, and chemotherapy given through a lumbar puncture. It is for people with lung cancer that has spread to the lining of the brain and has not responded to standard treatments.
Chengdu, SichuanAges 18–75 - NCT06431711Recruiting
Eye scan study for brain small vessel disease
This study uses a special eye scan (OCTA) to check the health of tiny blood vessels in the back of the eye. It may help doctors understand small vessel disease in the brain and find easier ways to monitor it.
Hangzhou, ZhejiangAges 35 years+ - NCT06432907Recruiting
Brain signal study during movement in epilepsy patients
This study records brain signals from electrodes already placed in your brain for medical reasons. It looks at how your brain controls movement, which could help develop future devices for people with paralysis.
MoscowAges 18–70 - NCT06433765Recruiting
BRIUMVI and pregnancy safety in multiple sclerosis
This study looks at the effects of the MS medication BRIUMVI on pregnancy and baby health. It compares women who took BRIUMVI during pregnancy to those who did not.
Wilmington, North CarolinaAges 15–50 - NCT06434571RecruitingPhase 2
Comparing two sleep treatments for people with MS
This trial tests if talking with a sleep coach by video is better than a web-based program for improving sleep, reducing fatigue, and protecting the brain in people with multiple sclerosis (MS). Both treatments focus on changing thoughts and habits around sleep.
Kansas City, KansasAges 18–65 - NCT06435195Recruiting
Study of rare pituitary and sellar region diseases
This study is collecting information from people with rare diseases of the pituitary gland or nearby areas. It aims to better understand these conditions and improve care.
Beijing, Beijing MunicipalityAges Any age - NCT06435520RecruitingPhase 4
Helping people stop sleep medications in primary care
This trial helps people who have been using sleep medications for a long time and want to stop. You will work with your primary care doctor to gradually reduce the medication and learn ways to sleep better without pills.
Denver, ColoradoAges 21 years+ - NCT06436716Recruiting
AI Model for Traumatic Neck Spinal Cord Injury
This study uses artificial intelligence and MRI scans to predict outcomes in people with a traumatic cervical spinal cord injury. The AI model combines imaging data with genetic information to help doctors make better treatment decisions.
Nantong, JiangsuAges Any age - NCT06437132Recruiting
Digital Thanotyping for End-of-Life Care in Dementia
This study tests a digital system (called 'thanotyping') to better understand the last stages of life in people with dementia who live in nursing homes. The goal is to improve care and support for both patients and families during this time.
Bergen, VestlandAges 65 years+ - NCT06437587Recruiting
Home rehab with simple tech for stroke recovery
This trial tests a home-based rehabilitation program using simple technology to help people who have had a stroke and still have trouble moving an arm or leg. It aims to see if doing exercises at home can improve your recovery.
Daqing, HeilongjiangAges 18 years+ - NCT06437600Recruiting
Immediate balloon angioplasty for severe stroke with brain artery narrowing
This trial tests whether doing an angioplasty (a procedure to open a narrowed artery with a small balloon) as soon as possible after a severe stroke caused by a blockage in a brain artery can improve recovery. It is for people who arrive within 24 hours of their stroke and have a specific type of narrowing inside the skull.
Guangzhou, GuangdongAges 18 years+ - NCT06438419Recruiting
Brain activity in Parkinson's during movement with DBS
This study records brain activity during movement in people with Parkinson's who have a special deep brain stimulation (DBS) device. It aims to understand how brain rhythms relate to movement, which could improve future treatments.
BordeauxAges 18–75 - NCT06438965Recruiting
Light test for muscle & nerve disease in kids
This study uses a safe, non-invasive light test (called MSOT) to help diagnose and monitor children with muscle or nerve diseases. It aims to find better ways to track these conditions without needles or radiation.
Ottawa, OntarioAges Up to 18 years - NCT06438900Recruiting
Studying AGEs and muscle loss in obesity and diabetes
This study is looking at how certain sugar-related proteins (called AGEs) might be linked to muscle loss in people with obesity and type 2 diabetes. It aims to understand why muscle wasting happens in this condition.
NovaraAges 18 years+
Common questions
- How many brain & nervous system clinical trials are recruiting?
- Clin2 is tracking 12,432 recruiting neurology studies from the U.S. registry right now, out of 19,532 we cover in this area in total.
- What does “Brain & nervous system” cover here?
- Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We group each study into brain & nervous system based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a brain & nervous system trial near me?
- Use the search to filter brain & nervous system studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.