Neurology
Brain & nervous system clinical trials
Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We’re tracking 11,934 recruiting studies in this area right now.
By phase
- Not applicable9,337
- Phase 2764
- Phase 1555
- Phase 3514
- Phase 4340
- Phase 1/Phase 2299
- Phase 2/Phase 3125
Top conditions
- Stroke797
- Parkinson Disease395
- Alzheimer Disease337
- Multiple Sclerosis330
- Dementia224
- Epilepsy192
- Ischemic Stroke190
- Insomnia159
- Traumatic Brain Injury151
- Obstructive Sleep Apnea142
- Spinal Cord Injuries142
- Acute Ischemic Stroke139
- Sarcopenia135
- Mild Cognitive Impairment126
- Cerebral Palsy119
- Pain Management113
- Migraine107
- Fibromyalgia105
Leading sponsors
- Beijing Tiantan Hospital124
- Assistance Publique - Hôpitaux de Paris109
- Riphah International University105
- Mayo Clinic98
- VA Office of Research and Development92
- Xuanwu Hospital, Beijing89
- Hospices Civils de Lyon77
- Johns Hopkins University69
- University of Minnesota63
- Washington University School of Medicine63
Where studies are running
- California655
- Massachusetts304
- New York295
- Florida267
- Texas267
- Maryland248
- Arizona209
- Alabama205
- Illinois183
- Pennsylvania175
Recruiting studies11,934 total
- NCT05659524Recruiting
Saline rinse after pituitary nose surgery study
This study checks whether rinsing your nose with saline (salt water) after pituitary surgery improves comfort and nasal breathing. It may help patients reduce post-surgery nasal irritation and support better nose outcomes.
Phoenix, ArizonaAges 19–85 - NCT06375759Recruiting
Surgery comparison for spinal cavity from injury or infection
This trial tests two surgical options for people with a spinal cord injury or infection that caused a fluid-filled cavity (syrinx) in the spine. It compares a new type of bypass surgery with a procedure to remove scar tissue, to see which helps improve symptoms better.
Beijing, Beijing MunicipalityAges 18–80 - NCT06380777Recruiting
Digital system for diagnosing and treating sarcopenia
This study is testing a new digital system to help diagnose and manage sarcopenia (age-related muscle loss). It aims to make it easier for doctors to track and treat muscle loss, which can improve your strength and quality of life.
Beijing, Beijing MunicipalityAges 45 years+ - NCT05070078Recruiting
Assessing recovery after lumbar disc surgery using SANE
This study uses a simple recovery questionnaire called SANE to understand how people do after lumbar discectomy (surgery to relieve a slipped or herniated disc). It may help the care team measure recovery in a clearer, more consistent way.
Windsor, OntarioAges 18 years+ - NCT05309473Recruiting
Sounds during restricted sleep after being sleep deprived
This study tests whether playing certain sounds during a period of limited sleep can affect how your body responds after you’ve been kept awake. It’s designed for healthy adults and checks safety and how well you can follow the study instructions.
Silver Spring, MarylandAges 18–39 - NCT06346535Recruiting
PrimeCog: New thinking tests for recent depression or stress diagnosis
This trial studies new digital tests that could help doctors in primary care detect cognitive (thinking) problems in people recently diagnosed with depression or stress-related disorders. The goal is to find reliable early signs of cognitive changes so treatment can be better tailored.
Linköping, Östergötland CountyAges 18–65 - NCT06380387Recruiting
Metabolism in children before and after brain tumor treatment
This study looks at how the body's energy use (metabolism) changes in children with a brain tumor before and after treatment. The goal is to understand how the tumor and its treatment affect the body, which may help improve care in the future.
Copenhagen, Copenhagen ØAges 6–18 - NCT03749980Recruiting
Study following people with von Hippel-Lindau (VHL)
This study follows people who have von Hippel-Lindau (VHL) over time to better understand how the condition changes. It may help doctors plan future treatments by collecting long-term health information.
Boston, MassachusettsAges Any age - NCT06385951Recruiting
Virtual reality navigation test for early Alzheimer's detection
This study uses a virtual reality navigation task to detect early signs of Alzheimer's disease. It compares people with mild cognitive problems, mild Alzheimer's, and healthy older adults to see if this test can spot the disease earlier.
Ghent, East-FlandersAges 50–80 - NCT06387875Recruiting
Community health study in Qianwan, Ningbo
This study is creating a health database of people living in Qianwan New District, Ningbo. Researchers will ask about your health and lifestyle, and follow up over time to learn about community well-being.
ShanghaiAges 18 years+ - NCT06140719Recruiting
Study to speed up DIPG and DMG research
This trial collects information from people with a rare type of brain tumor called DIPG or DMG. The goal is to help researchers learn more about these tumors and find better treatments faster.
Los Altos, CaliforniaAges Any age - NCT06342570Recruiting
EEG changes during pain for laparoscopic surgery patients
This study measures brain wave changes in response to pain during laparoscopic surgery. It aims to improve how pain is monitored under anesthesia.
SeoulAges 19 years+ - NCT06394453Recruiting
Feeding during cooling for brain injury in newborns
This study looks at whether it is safe to give small amounts of milk to babies who are being cooled for brain injury after a difficult birth. It may help doctors decide if feeding during cooling can improve outcomes.
CracowAges Up to 6 hours - NCT05808153Recruiting
Brain scans and thinking tests to track Huntington’s progression
This study uses special brain imaging and memory/thinking tests to find early “markers” that can predict how Huntington’s disease will progress over time. You may qualify as someone with early-stage Huntington’s or as a healthy control, if you meet specific safety and scoring requirements.
Créteil, Île-de-France RegionAges 18–65 - NCT06390761Recruiting
Acupuncture for constipation in Parkinson's disease
This trial tests whether acupuncture can help relieve constipation in people with Parkinson's disease. If you have both Parkinson's and constipation that is not caused by another medical condition, this study may offer a non-drug treatment option.
Xi'an, ShaanxiAges 35–80 - NCT05539677Recruiting
Research biobank and patient registry for aggressive solid tumors
This study builds a biobank and patient registry using tumor samples and blood. It helps researchers better understand aggressive cancers and may improve future treatments by testing immune (defense) responses.
Saint PetersburgAges 1 year+ - NCT06400940RecruitingPhase 4
Testing a flow-diverting stent for brain aneurysms that returned
This trial tests a special stent (DERIVO) for brain aneurysms that have come back after earlier treatment. It's for people who cannot have other treatments like coiling or surgery.
Saint PetersburgAges 18 years+ - NCT06401057Recruiting
Long-term brain function tracking for brain lesions
This study creates a registry to track brain function over time in people with brain lesions. It aims to better understand how the brain works and may help improve future care.
HeidelbergAges 18 years+ - NCT06399926Recruiting
Pemetrexed via Ommaya for lung cancer in brain lining
This study tests whether a drug called pemetrexed, given directly into the fluid around your brain through a small implanted device, is safe and effective for treating lung cancer that has spread to the lining of the brain. It is for people whose cancer has a specific genetic change (EGFR, ALK, or ROS1) and who have already tried standard targeted pills that no longer control their disease.
Changsha, HunanAges 18 years+ - NCT06401564Recruiting
Virtual reality rehab after ischemic stroke
This study tests whether using virtual reality (VR) exercises in the hospital can help people recover arm movement and function after an ischemic stroke. You may be a candidate if you have weakness in one arm and can follow directions.
Stony Brook, New YorkAges 18 years+ - NCT05832515RecruitingPhase 1
Stem cell transplant for multiple sclerosis with MS-prep chemotherapy
This early-phase study tests a stem cell transplant procedure for people with multiple sclerosis whose usual MS medicines have not worked or can’t be tolerated. The goal is to see if this approach can help control MS activity and progression, while checking for safety.
Saint PetersburgAges 18–65 - NCT06398353Recruiting
Acupuncture for frequent primary headaches
This study tests whether acupuncture can improve quality of life for people with frequent primary headaches (like migraines or tension headaches). If you have headaches more than twice a week, this trial may help you find relief.
Taoyuan, Select A StateAges 18 years+ - NCT04126369Recruiting
Mindfulness program to improve quality of life in drug-resistant epilepsy
This trial tests whether a mindfulness training program can improve quality of life for people with drug-resistant epilepsy. It looks at whether learning mindfulness skills helps you cope day-to-day alongside your usual treatment.
GrenobleAges 18 years+ - NCT05296980Recruiting
Testing a dementia risk-reduction program for older adults
This study checks whether a program called REMINDER can help reduce risk of developing dementia by improving risk factors over 12 weeks. It’s for older adults who have higher dementia risk but do not currently have dementia.
CoimbraAges 60–75
Common questions
- How many brain & nervous system clinical trials are recruiting?
- Clin2 is tracking 11,934 recruiting neurology studies from the U.S. registry right now, out of 18,325 we cover in this area in total.
- What does “Brain & nervous system” cover here?
- Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We group each study into brain & nervous system based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a brain & nervous system trial near me?
- Use the search to filter brain & nervous system studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.