Neurology
Brain & nervous system clinical trials
Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We’re tracking 12,462 recruiting studies in this area right now.
By phase
- Not applicable9,797
- Phase 2786
- Phase 1574
- Phase 3538
- Phase 4342
- Phase 1/Phase 2304
- Phase 2/Phase 3121
Top conditions
- Stroke854
- Parkinson Disease424
- Multiple Sclerosis342
- Alzheimer Disease340
- Dementia226
- Ischemic Stroke199
- Epilepsy196
- Obstructive Sleep Apnea155
- Spinal Cord Injuries154
- Insomnia152
- Traumatic Brain Injury152
- Sarcopenia148
- Acute Ischemic Stroke141
- Cerebral Palsy130
- Mild Cognitive Impairment129
- Pain Management114
- Migraine113
- Amyotrophic Lateral Sclerosis107
Leading sponsors
- Beijing Tiantan Hospital134
- Riphah International University125
- Assistance Publique - Hôpitaux de Paris112
- Mayo Clinic99
- Xuanwu Hospital, Beijing95
- VA Office of Research and Development93
- Hospices Civils de Lyon79
- Johns Hopkins University70
- National Taiwan University Hospital70
- Cairo University63
Where studies are running
- California675
- Massachusetts301
- New York292
- Florida277
- Texas267
- Maryland244
- Arizona216
- Alabama211
- Illinois193
- Pennsylvania177
Recruiting studies12,460 total
- NCT06677970RecruitingPhase 3
Blood Pressure Control After Stroke Thrombectomy
This trial tests whether carefully lowering blood pressure after a mechanical clot removal procedure for stroke can improve outcomes. If you've had a large vessel stroke that was successfully treated with thrombectomy, this study will help guide blood pressure management in the recovery period.
Seoul, SeoulAges 20 years+ - NCT06678100Recruiting
Swallowing study for adults with Alzheimer's
This study looks at swallowing problems in people with Alzheimer's disease compared to healthy older adults. If you have Alzheimer's, you'll have a swallowing test and your caregiver will answer questions about your daily life.
Nashville, TennesseeAges 60 years+ - NCT06678347Recruiting
Leadership program for healthcare managers
This trial tests a program to help first-line managers in hospitals lead better and support their teams. It may benefit managers and their employees by improving work recovery and well-being.
GothenburgAges 18 years+ - NCT06678529Recruiting
Can brain stimulation prevent confusion after hip surgery?
This study tests if a gentle, noninvasive brain stimulation called transcranial direct current stimulation (tDCS) can reduce postoperative delirium (sudden confusion) in older adults recovering from hip fracture surgery. It aims to see if tDCS is a safe, drug-free way to protect brain function.
Taiyuan, ShanxiAges 65 years+ - NCT06678737RecruitingPhase 2
TMS plus behavioral therapy for teens with tics
This study tests whether combining a brain stimulation technique called TMS with behavioral therapy can reduce tics in adolescents and young adults. If you have had tics for at least a year and they are moderate or severe, this trial may be a good fit.
Minneapolis, MinnesotaAges 12–21 - NCT06679062RecruitingPhase 2
Suvorexant for alcohol use disorder and PTSD
This study tests whether the sleep medication suvorexant can help people with both alcohol use disorder and PTSD. If you're struggling with drinking, PTSD symptoms, and poor sleep, this trial may offer a new treatment option.
Los Angeles, CaliforniaAges 21–65 - NCT06679374RecruitingPhase 2
Can varenicline help reduce falls in Parkinson disease?
This phase 2 trial tests a medicine called varenicline (brand name Chantix) to see if it can reduce falls in people with Parkinson disease who also have a specific brain change (loss of a chemical called acetylcholine in the back of the brain) and mild cognitive problems. The study will help determine if this medicine is safe and effective for this group.
Ann Arbor, MichiganAges 45 years+ - NCT06679296Recruiting
Aging and Memory Loss Study in China
This study looks at how aging affects memory and thinking. It uses brain scans, a spinal tap, and other tests to understand cognitive decline better.
Wenzhou, ZhejiangAges Any age - NCT06679543Recruiting
How partial sleep loss affects heart function during cycling
This study looks at how a night of poor sleep affects your heart's ability to pump blood while you ride a bike. It may help find out why sleep loss can be hard on the heart.
Guelph, OntarioAges 18–50 - NCT06679816RecruitingPhase 4
Hydrocortisone for hormone replacement in large pituitary tumor surgery
This trial tests hydrocortisone as hormone replacement therapy after surgery for large pituitary tumors. It aims to help patients maintain healthy cortisol levels during recovery.
Beijing, Beijing MunicipalityAges 18–70 - NCT06680011Recruiting
Study of diagnostic markers for neurosyphilis
This study looks for better ways to diagnose neurosyphilis, an infection that affects the brain and spinal cord. Researchers will compare test results from people with neurosyphilis, people with syphilis but no brain involvement, and healthy volunteers.
Shanghai, Shanghai MunicipalityAges 18–65 - NCT06680934Recruiting
CABP2 patient registry and natural history study
This study tracks people with hearing loss caused by changes in the CABP2 gene. It aims to understand how the condition develops over time.
GöttingenAges Any age - NCT06681207Recruiting
Exploring brain stimulation for stepping after stroke
This study tests whether a mild electrical brain stimulation can help people with chronic stroke improve their stepping and walking. If you have had a stroke at least 6 months ago, can walk with or without a device, and have some leg weakness, this study may be for you.
Galveston, TexasAges 21–90 - NCT06681610Recruiting
Testing pulse stimulation to improve movement in ALS
This trial studies if a non-invasive pulse stimulation can help people with ALS move better. It aims to see if this treatment can improve motor function.
Barcelona, CataloniaAges 21–80 - NCT06681623Recruiting
Ublituximab in older adults with relapsing MS
This study is testing how safe and effective the medication ublituximab is for older adults (ages 55–80) with relapsing multiple sclerosis. It aims to see if this treatment works well for this age group.
Foxborough, MassachusettsAges 55–80 - NCT06681649Recruiting
ICU follow-up care for survivors and their caregivers
This study tests a bundle of follow-up care for ICU survivors and their caregivers after leaving the hospital. It aims to improve recovery and support for both patients and their families.
Kingston, OntarioAges 18 years+ - NCT06681974RecruitingPhase 3
Throat therapy for sleep apnea without CPAP
This trial tests a type of mouth and throat therapy to see if it can help people with mild to moderate sleep apnea who can't or don't want to use a CPAP machine. It might be an option if you want a non-machine treatment for your sleep apnea.
SantanderAges 18–70 - NCT06682286Recruiting
Breathing patterns during nighttime NIV
This study looks at how people breathe while using their nighttime breathing machine (NIV). It helps doctors understand breathing patterns better for people with COPD or OHS.
AucklandAges 18 years+ - NCT06682416Recruiting
Does the temperature of pain relief medicine affect fever during labor?
This study tests whether using a warmer or cooler numbing medicine during an epidural changes the chance of a mother developing a fever during labor. If you are planning an epidural for vaginal delivery, this trial may help improve pain relief and reduce fever risk.
Suzhou, JiangsuAges 18 years+ - NCT06682429Recruiting
Home rehab program after stroke
This study tests a home-based therapy program delivered by video calls to help people recovering from a stroke improve arm function. It is designed for those with moderate arm weakness about 4 months after their stroke.
Downey, CaliforniaAges 18–80 - NCT06682819Recruiting
Looking at eye nerve layers in NOHL gene carriers
This study uses a special eye scan (OCT) to look at the layer of nerve fibers in the retina of people who carry (or don't carry) a specific gene change linked to Leber Hereditary Optic Neuropathy (NOHL). The goal is to find early warning signs in the blood that might show who is at risk of losing vision.
Paris, ParisAges 18–60 - NCT06683248Recruiting
Night shifts and menstrual cycle health study
This study looks at how working night shifts affects your health throughout your menstrual cycle. It aims to help understand the risks and support better health for shift workers.
Uppsala, Uppsala CountyAges 18–35 - NCT06683365RecruitingPhase 1
Nerve graft trial for Parkinson's or MSA
This trial tests whether grafting a piece of your own leg nerve into a specific part of the brain can improve symptoms of Parkinson's disease or multiple system atrophy (MSA). It aims to help people whose movement problems are moderate but not too severe.
Lexington, KentuckyAges 40–75 - NCT06684249Recruiting
Comparing nerve block and Botox for chronic migraine
This study compares two treatments for chronic migraine: a nerve block (injection near the nerves in the head) and Botox injections. It aims to see which one works better to reduce headache days and improve quality of life.
Zagazig, Sharqia ProvinceAges 18–65
Common questions
- How many brain & nervous system clinical trials are recruiting?
- Clin2 is tracking 12,462 recruiting neurology studies from the U.S. registry right now, out of 19,649 we cover in this area in total.
- What does “Brain & nervous system” cover here?
- Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We group each study into brain & nervous system based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a brain & nervous system trial near me?
- Use the search to filter brain & nervous system studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.