Neurology
Brain & nervous system clinical trials
Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We’re tracking 12,462 recruiting studies in this area right now.
By phase
- Not applicable9,797
- Phase 2786
- Phase 1574
- Phase 3538
- Phase 4342
- Phase 1/Phase 2304
- Phase 2/Phase 3121
Top conditions
- Stroke854
- Parkinson Disease424
- Multiple Sclerosis342
- Alzheimer Disease340
- Dementia226
- Ischemic Stroke199
- Epilepsy196
- Obstructive Sleep Apnea155
- Spinal Cord Injuries154
- Insomnia152
- Traumatic Brain Injury152
- Sarcopenia148
- Acute Ischemic Stroke141
- Cerebral Palsy130
- Mild Cognitive Impairment129
- Pain Management114
- Migraine113
- Amyotrophic Lateral Sclerosis107
Leading sponsors
- Beijing Tiantan Hospital134
- Riphah International University125
- Assistance Publique - Hôpitaux de Paris112
- Mayo Clinic99
- Xuanwu Hospital, Beijing95
- VA Office of Research and Development93
- Hospices Civils de Lyon79
- Johns Hopkins University70
- National Taiwan University Hospital70
- Cairo University63
Where studies are running
- California675
- Massachusetts301
- New York292
- Florida277
- Texas267
- Maryland244
- Arizona216
- Alabama211
- Illinois193
- Pennsylvania177
Recruiting studies12,460 total
- NCT06691165RecruitingPhase 1/Phase 2
Low oxygen therapy for blood pressure in spinal cord injury
This trial tests whether breathing low oxygen (hypoxia) can help stabilize blood pressure in people with spinal cord injuries. It's looking for participants with chronic cervical injuries to see if this therapy improves 24-hour blood pressure control.
Kelowna, British ColumbiaAges 19–65 - NCT06691230Recruiting
Looking at blood flow after stroke clot removal
This study uses a special CT scan to see how well blood flows in the brain after a stroke patient has had a procedure to remove a clot. The goal is to learn more about recovery and improve future care.
BaselAges 18 years+ - NCT06691698Recruiting
CO-OP therapy for teens with mild intellectual disability
This study tests a therapy called CO-OP, which helps teens with mild intellectual disability learn skills to reach their own goals. You'll work with a therapist once a week for 10 weeks, with a parent or adult to support you.
Kristianstad, Skåne CountyAges 13–17 - NCT06692296Recruiting
Balance training with a stabilometric platform for Friedreich's ataxia
This trial tests if a special platform that measures balance can help people with Friedreich's ataxia stand more steadily. If you have Friedreich's ataxia, can walk at least 10 metres and stand without support, you may be eligible.
Pieve di Soligo, VenetoAges 14 years+ - NCT06692426RecruitingPhase 1
Cell therapy for Duchenne muscular dystrophy
This trial tests a new cell-based treatment for Duchenne muscular dystrophy in adults who can no longer walk. The goal is to see if the therapy can help improve muscle function.
Minneapolis, MinnesotaAges 18 years+ - NCT06692569Recruiting
Modified physical therapy for arm and hand recovery after stroke
This study tests a type of physical therapy called modified constraint-induced movement therapy to help improve arm and hand function in people who have had a stroke more than six months ago. You will be encouraged to use your affected arm more often while the stronger arm is gently restricted, which may help retrain your brain and improve movement.
Riyadh, Riyadh RegionAges 45–65 - NCT06692712RecruitingPhase 3
Gene therapy study for children with SPG50
This study tests a gene therapy called IT MELPIDA for children with SPG50, a genetic condition that affects movement and development. The treatment is given through a lumbar puncture (spinal tap) and aims to slow or stop the loss of motor skills.
Dallas, TexasAges 4 months–6 years - NCT06692920Recruiting
Parkinson's brain signals study during DBS surgery
This study looks at brain signals in people with Parkinson's who are already scheduled for Deep Brain Stimulation (DBS) surgery. The goal is to better understand how certain brain pathways work, which could lead to improved treatments.
Minneapolis, MinnesotaAges 21–75 - NCT06693011Recruiting
Testing the Contour device for brain aneurysms
This trial tests a device called Contour to treat a specific type of brain aneurysm (like a bubble on a blood vessel). It may be an option if you have one aneurysm that needs treatment and it fits certain size and shape requirements.
Park Ridge, IllinoisAges 18–75 - NCT06693388Recruiting
Vibration and casting for kids with cerebral palsy
This study tests whether whole body vibration (standing on a gently shaking platform) plus leg casting can help children with cerebral palsy improve ankle flexibility and walking. It is for children who already need casting for tight ankles.
Columbus, OhioAges 3–17 - NCT06694441Recruiting
Sleep, brain chemicals, and memory in older adults with insomnia
This study looks at how a brain chemical called norepinephrine affects sleep and thinking in older adults with insomnia. You may join if you are 55+, have insomnia, and are generally healthy.
Chicago, IllinoisAges 55 years+ - NCT06695312Recruiting
High Tone Power Therapy for Neck Pain and Body Awareness
This trial tests a type of physical therapy called High Tone Power Therapy for people with long-term neck pain from a herniated disc in the neck. It aims to reduce pain and improve your sense of where your neck is in space (proprioception) without needing surgery.
Giza, Giza GovernorateAges 35–50 - NCT06695455Recruiting
Can music help people with Parkinson's swallow better?
This trial tests if a rhythmic sound cue can reduce rolling (a swallowing problem) in people with Parkinson's. If you have trouble with solid foods but not severe liquid aspiration, you may qualify.
Saint-Sébastien-de-Morsent, NormandyAges 18 years+ - NCT06695767Recruiting
Behavioral therapy for epilepsy and depression in veterans
This trial tests a special therapy program for veterans who have both epilepsy and major depression. It uses talk therapy and text message support to help improve mood and seizure control.
Houston, TexasAges 18 years+ - NCT06696027Recruiting
Loss of Y chromosome in autoimmune and lung disease
This study looks at how the loss of the Y chromosome in blood cells may be linked to autoimmune and lung diseases in older men. By joining, you help researchers understand this connection better.
Bonn, North Rhine-WestphaliaAges 50 years+ - NCT06696079Recruiting
Early vs later blood thinner restart after brain bleed surgery in atrial fibrillation
This trial compares restarting a blood thinner early (within a few days) versus later (after about a week) in people who have a chronic subdural hematoma drained and also have atrial fibrillation. The goal is to find out which timing helps prevent both new bleeding and blood clots.
Oulu, North OstrobothniaAges 18 years+ - NCT06696287Recruiting
6-minute hand and arm test in fibromyalgia
This study tests a simple 6-minute hand and arm exercise (pegboard and ring test) in people with fibromyalgia. It helps researchers understand how well you can use your hands and arms during daily activities.
KırşehirAges 18–65 - NCT06696469Recruiting
Virtual reality for arm recovery after stroke
This trial tests if a virtual reality system called BeCure can help people who had a stroke recover arm movement. It's for people who are still in the early to later stages of recovery (not the very first days) and have some movement and sitting balance.
AnkaraAges 18–80 - NCT06696573Recruiting
Anti-inflammatory drugs for pain during medical abortion
This study tests whether giving anti-inflammatory drugs before or during a medical abortion (13–22 weeks) can help prevent pain better than treating pain once it starts. If you're eligible, taking part may help improve pain management for future patients.
Ho Chi Minh CityAges 18 years+ - NCT06696703Recruiting
Human urinary kallidinogenase for acute ischemic stroke
This trial tests whether a medicine called human urinary kallidinogenase can reduce inflammation after a stroke. It may help people who have had a first or recent stroke and have certain levels of disability.
Harbin, HeilongjiangAges 18 years+ - NCT06696898Recruiting
Stretching with and without muscle release for sciatica
This study tests if adding myofascial release (a type of hands-on therapy for tight muscles) to a standard self-stretching program helps relieve sciatica pain and improve movement. It's for people with long-standing (chronic) one-sided sciatica.
Lahore, Punjab ProvinceAges 25–50 - NCT06697158Recruiting
Lymphedema therapy and its effect on sleep and quality of life
This study tests a treatment called complex decongestive physiotherapy for women who have swelling in one arm after breast cancer surgery. It looks at whether this therapy can improve their sleep and overall quality of life.
BoluAges 18–85 - NCT06697470Recruiting
Ultrasound and fluid monitoring in the ICU
This study uses ultrasound and electrical impedance (skin electrodes) to track fluid balance in the muscles and tissues of ICU patients. It aims to see if these tools can help doctors better manage fluids during your stay.
Boussu, HainautAges 18 years+ - NCT06697535RecruitingPhase 2
Study of JYP0061 for acute NMOSD attacks
This trial tests a new medication called JYP0061 for people with NMOSD who are currently experiencing a sudden worsening of symptoms (acute attack). It aims to see if the drug can help control the attack and improve outcomes.
Changsha, HunanAges 18–65
Common questions
- How many brain & nervous system clinical trials are recruiting?
- Clin2 is tracking 12,462 recruiting neurology studies from the U.S. registry right now, out of 19,649 we cover in this area in total.
- What does “Brain & nervous system” cover here?
- Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We group each study into brain & nervous system based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a brain & nervous system trial near me?
- Use the search to filter brain & nervous system studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.