Neurology
Brain & nervous system clinical trials
Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We’re tracking 12,462 recruiting studies in this area right now.
By phase
- Not applicable9,797
- Phase 2786
- Phase 1574
- Phase 3538
- Phase 4342
- Phase 1/Phase 2304
- Phase 2/Phase 3121
Top conditions
- Stroke854
- Parkinson Disease424
- Multiple Sclerosis342
- Alzheimer Disease340
- Dementia226
- Ischemic Stroke199
- Epilepsy196
- Obstructive Sleep Apnea155
- Spinal Cord Injuries154
- Insomnia152
- Traumatic Brain Injury152
- Sarcopenia148
- Acute Ischemic Stroke141
- Cerebral Palsy130
- Mild Cognitive Impairment129
- Pain Management114
- Migraine113
- Amyotrophic Lateral Sclerosis107
Leading sponsors
- Beijing Tiantan Hospital134
- Riphah International University125
- Assistance Publique - Hôpitaux de Paris112
- Mayo Clinic99
- Xuanwu Hospital, Beijing95
- VA Office of Research and Development93
- Hospices Civils de Lyon79
- Johns Hopkins University70
- National Taiwan University Hospital70
- Cairo University63
Where studies are running
- California675
- Massachusetts301
- New York292
- Florida277
- Texas267
- Maryland244
- Arizona216
- Alabama211
- Illinois193
- Pennsylvania177
Recruiting studies12,460 total
- NCT06731673Recruiting
HSP47 protein study in blood clots
This study looks at a protein called HSP47 in people with blood clots, heart attacks, or strokes caused by atrial fibrillation, compared to healthy volunteers. It aims to learn more about how blood clots form and may lead to better treatments.
Aarhus, Central RegionAges 18 years+ - NCT06731868RecruitingPhase 1/Phase 2
Study of an experimental tablet for tardive dyskinesia
This study tests an experimental once-daily tablet for moderate-to-severe tardive dyskinesia, a condition causing uncontrollable repetitive movements. It aims to see if the drug is safe and reduces these symptoms over time.
ShanghaiAges 18–64 - NCT06731998Recruiting
Improving pain control after cancer surgery
This study compares different methods of managing pain after minimally invasive surgery for abdominal cancers. It aims to find which approach works best to reduce pain and improve recovery.
Pittsburgh, PennsylvaniaAges 18–89 - NCT06732180RecruitingPhase 1
Testing a new drug (GT-02287) for Parkinson's disease
This trial tests an investigational drug called GT-02287 in people with early-stage Parkinson's disease (diagnosed within the last 7 years). The goal is to see if it is safe and how the body processes it, with a special focus on people with certain genetic changes (GBA1 mutations) that may be linked to Parkinson's.
Darlinghurst, New South WalesAges 30–85 - NCT06732128Recruiting
Nature virtual reality for depression in Alzheimer's disease
This trial tests whether a virtual reality nature experience can help improve mood in people with early-to-moderate Alzheimer's disease. Participants will use a VR headset and a few apps at home, with a caregiver present, over several sessions.
Toronto, OntarioAges 50 years+ - NCT06732284Recruiting
Sleep inertia study in depression
This study looks at sleep inertia (the grogginess you feel after waking up) in people with major depression. It uses a simple reaction-time test to understand how depression affects waking up.
NîmesAges 18–54 - NCT06732622Recruiting
Laser Acupuncture for Bell's Palsy
This trial tests laser acupuncture as a needle-free treatment for Bell's palsy (sudden facial weakness). It might help people with moderate to severe symptoms who start treatment within 8 weeks of onset.
Beijing, Beijing MunicipalityAges 18–65 - NCT06732674Recruiting
Home-based care for lung disease in rheumatic conditions
This trial tests whether people with lung disease caused by a rheumatic condition can safely manage their care at home using a smartphone or tablet. It aims to see if home monitoring is as effective as in-person visits for keeping your lungs healthy.
OsloAges 18 years+ - NCT06732713Recruiting
Swiss ball vs. Frenkel exercises for Down syndrome
This trial compares using a Swiss ball versus Frenkel exercises to improve balance and coordination in children with Down syndrome. It may help children who can stand and walk on their own.
Lahore, Punjab ProvinceAges 8–13 - NCT06733025Recruiting
Comparing surgery and Botox for arm spasticity
This trial compares two treatments—Botox injections or surgery—for arm and hand spasticity after a stroke, brain injury, or spinal cord injury. It may help you decide which option works best for you.
MölndalAges 18 years+ - NCT06733077Recruiting
Digital services for Parkinson's disease
This study is developing digital services for people with Parkinson's disease and also includes healthy volunteers. It aims to understand movement problems like freezing of gait and festination, and uses a virtual reality system to measure these issues.
ExeterAges 18 years+ - NCT06733220Recruiting
Balance in strabismus patients having eye muscle surgery
This study looks at how strabismus (misaligned eyes) affects balance before and after surgery. It may help patients understand if their eye condition influences their stability.
Roma, RMAges 16–65 - NCT06733246Recruiting
Ceretrieve Device for acute ischemic stroke treatment
This study tests a new device called Ceretrieve that is designed to remove blood clots from large arteries in the brain for people having a severe ischemic stroke. If you are eligible, you will receive the device treatment (a mechanical thrombectomy) within 24 hours of your first symptoms.
HeidelbergAges 18 years+ - NCT06733636Recruiting
Smell training for older adults with smell loss
This study tests whether a special device can help older adults regain their sense of smell through regular training with different scents. It is designed for people who have lost smell due to aging or other causes, not from birth.
Baltimore, MarylandAges 60 years+ - NCT06733714Recruiting
Brain stimulation plus memory training for older adults
This study tests whether a gentle, non-invasive electrical current applied to the scalp (tACS) combined with computer-based brain exercises can improve memory and thinking in older adults who have concerns about their cognitive health.
Rio de Janeiro, Rio de JaneiroAges 50 years+ - NCT06733922RecruitingPhase 4
Tracking MS changes with ofatumumab in active relapsing MS
This study looks at whether blood tests and eye-tracking tasks can show how well ofatumumab slows or stops MS damage. It's for people starting ofatumumab as part of their regular care who have active relapsing-remitting MS.
Calgary, AlbertaAges 18–99 - NCT06734026Recruiting
Enriched environment rehab for chronic brain injury
This study tests a rich, supportive environment (including exercise, social activities, and cognitive tasks) to help people with chronic brain injury improve their mobility and overall function. If you have a brain injury that happened more than 3 months ago and can stand with support, you may be able to join a program that focuses on your recovery.
Cleveland, OhioAges 18 years+ - NCT06734000Recruiting
Spinal cord injury study with tissue samples
This trial collects tissue samples from people with new spinal cord injuries to study recovery. It may help researchers understand how to improve treatment.
Nantes, Loire-AtlantiqueAges 16 years+ - NCT06734546Recruiting
Exercise and brain health in type 2 diabetes
This study tests whether regular exercise can improve brain health in people with type 2 diabetes. If you have type 2 diabetes, are not on insulin, are inactive, and are between 30 and 75 years old, you may be able to join.
Hasselt, LimburgAges 30–75 - NCT06734598RecruitingPhase 4
Botox for Jaw Tightness After Head and Neck Radiation
This study tests whether Botox injections into the jaw muscles can help head and neck cancer survivors who have trouble opening their mouths (trismus) after radiation therapy. If you have tight or painful jaw muscles and limited mouth opening, this treatment may offer relief.
TaipeiAges 18 years+ - NCT06734689Recruiting
Genes and heart inflammation from immunotherapy
This study looks at genetic factors that may affect the risk of heart inflammation (myocarditis) caused by immune checkpoint inhibitors (ICIs), a type of cancer immunotherapy. It aims to find out if your genes make you more likely to develop this side effect.
ParisAges 18 years+ - NCT06735053Recruiting
Virtual reality physiotherapy for multiple sclerosis patients
This trial tests whether virtual reality exercises can help people with advanced multiple sclerosis improve their movement and walking. You may qualify if you need two walking aids and your MS has been stable for the last six months.
Móstoles, MadridAges 18–70 - NCT06735248RecruitingPhase 2
Study testing mRNA vaccine for multiple sclerosis relapse prevention
This study tests whether an mRNA vaccine (mRNA-1195) can help prevent relapses in people with early relapsing multiple sclerosis (MS). It compares the vaccine to a placebo (a shot with no active ingredient) to see if it is safe and effective.
Boston, MassachusettsAges 18–55 - NCT06735768Recruiting
Daily magnetic brain stimulation to prevent migraines
This study tests a type of magnetic brain stimulation (repetitive TMS) given daily at home to prevent migraines. It may be an option if your migraine medications aren't enough or you want a non-drug treatment.
Vienna, State of ViennaAges 18–65
Common questions
- How many brain & nervous system clinical trials are recruiting?
- Clin2 is tracking 12,462 recruiting neurology studies from the U.S. registry right now, out of 19,649 we cover in this area in total.
- What does “Brain & nervous system” cover here?
- Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We group each study into brain & nervous system based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a brain & nervous system trial near me?
- Use the search to filter brain & nervous system studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.