Neurology
Brain & nervous system clinical trials
Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We’re tracking 12,462 recruiting studies in this area right now.
By phase
- Not applicable9,797
- Phase 2786
- Phase 1574
- Phase 3538
- Phase 4342
- Phase 1/Phase 2304
- Phase 2/Phase 3121
Top conditions
- Stroke854
- Parkinson Disease424
- Multiple Sclerosis342
- Alzheimer Disease340
- Dementia226
- Ischemic Stroke199
- Epilepsy196
- Obstructive Sleep Apnea155
- Spinal Cord Injuries154
- Insomnia152
- Traumatic Brain Injury152
- Sarcopenia148
- Acute Ischemic Stroke141
- Cerebral Palsy130
- Mild Cognitive Impairment129
- Pain Management114
- Migraine113
- Amyotrophic Lateral Sclerosis107
Leading sponsors
- Beijing Tiantan Hospital134
- Riphah International University125
- Assistance Publique - Hôpitaux de Paris112
- Mayo Clinic99
- Xuanwu Hospital, Beijing95
- VA Office of Research and Development93
- Hospices Civils de Lyon79
- Johns Hopkins University70
- National Taiwan University Hospital70
- Cairo University63
Where studies are running
- California675
- Massachusetts301
- New York292
- Florida277
- Texas267
- Maryland244
- Arizona216
- Alabama211
- Illinois193
- Pennsylvania177
Recruiting studies12,460 total
- NCT06793800Recruiting
Ear nerve stimulation to improve breathing after stroke
This study tests whether a gentle nerve stimulation device placed on your ear can improve your breathing after a stroke. It's for people who had a first stroke 1 to 3 years ago and are otherwise generally healthy (no heart, lung, or ear problems).
IstanbulAges 40–80 - NCT06793839Recruiting
3D ultrasound imaging after brain bleed
This trial tests a new 3D ultrasound technique to see if it can better visualize blood flow in the brain after a subarachnoid hemorrhage (bleeding around the brain). It may help doctors monitor and treat patients more effectively.
CaenAges 18 years+ - NCT06793865Recruiting
Stimulation for ankle muscles to improve balance after stroke
This study tests a type of electrical stimulation, called Russian current, on the front shin muscles to see if it helps stroke patients stand steadier and lower their risk of falling.
MinyaAges 40–55 - NCT06794008RecruitingPhase 2
CAR-T cell therapy for hard-to-treat autoimmune diseases
This trial tests a new treatment using your own immune cells (called CAR-T cells) designed to target and attack cells that cause autoimmune diseases. It is for people with lupus, Sjögren's syndrome, inflammatory myopathy, scleroderma, Behcet's disease, ANCA-associated vasculitis, IgG4-related disease, antiphospholipid syndrome, or thrombotic thrombocytopenic purpura who have not improved with standard therapies.
Beijing, Beijing MunicipalityAges 18–65 - NCT06794489Recruiting
Tracking CMT with biomarkers over time
This study is looking for people with Charcot-Marie-Tooth disease (a nerve condition) and healthy volunteers to track long-term changes in the body. Researchers want to see if certain biomarkers (measurable signs) can help predict how CMT progresses over time.
Göttingen, Lower SaxonyAges 18–65 - NCT06794606Recruiting
Study for drug-resistant focal epilepsy
This trial looks at ways to diagnose and treat focal epilepsy that isn't controlled by medications. It includes patients with or without a visible brain lesion on imaging.
MilanAges 18 years+ - NCT06794853Recruiting
TIPS for improving muscle wasting in liver cirrhosis
This study looks at how a treatment called TIPS (a procedure to reduce pressure in the liver) might help improve muscle wasting (sarcopenia) in people with liver cirrhosis. If you are scheduled for TIPS, researchers want to see if it can stop or reverse muscle loss.
WuhanAges 18–80 - NCT06794879Recruiting
Parent survey on children's pain and sedation
This trial asks parents to fill out a survey about how their child's pain and sedation are managed during blood draws or other procedures. The goal is to understand parents' views and improve care for children.
Bologna, ItalyAges Any age - NCT06795230Recruiting
Arm exercise with blood flow cuffs for MS
This study tests a type of arm exercise that uses a blood pressure cuff to limit blood flow, aiming to improve arm function in people with multiple sclerosis. It may help if you have some arm weakness but no recent relapses or blood clotting issues.
Leganés, MadridAges 18 years+ - NCT06795152Recruiting
Rare GSD Natural History Study
This study follows people with rare types of glycogen storage disease (GSD) over time to learn more about how the disease progresses. It does not test a new treatment but will collect information to help future research.
Durham, North CarolinaAges birth–90 years - NCT06795243Recruiting
Physical therapy for endometriosis and exercise adherence
This study tests whether physical therapy (exercise for your muscles) can help with endometriosis symptoms and how well people stick with the program. If you have endometriosis and can do light strength exercises, you may be able to join.
SevilleAges 18 years+ - NCT06795867Recruiting
ACT therapy for chronic migraine disability
This study tests whether Acceptance and Commitment Therapy (ACT), a type of talk therapy that helps you accept difficult thoughts and feelings, can reduce disability caused by chronic migraine. You will be placed in one of two groups to compare ACT with your usual care.
Boston, MassachusettsAges 18–65 - NCT06795932Recruiting
Testing a new nerve stimulation device for frozen shoulder
This study tests if a non-invasive device that stimulates nerves can help treat frozen shoulder (adhesive capsulitis). If you are an adult with frozen shoulder and are in generally good health, you may be able to join to see if this device works.
Saguenay, QuebecAges 18 years+ - NCT06796595Recruiting
Nerve recovery program for chronic pelvic nerve pain
This study tests a medical program designed to help nerves heal better after surgery for long-term pelvic or buttock nerve pain. It looks at results one year after a minimally invasive operation to free compressed nerves.
BordeauxAges 18 years+ - NCT06796725Recruiting
Study of TMS for migraine guided by brain imaging
This study tests whether repetitive transcranial magnetic stimulation (rTMS), guided by magnetoencephalography (MEG), can help people with frequent migraines or tension-type headaches. If you have headaches 15 or more days per month, this treatment might reduce your pain.
ShanghaiAges 15–50 - NCT06796920Recruiting
Spinal cord stimulation for leg problems in adrenomyeloneuropathy
This trial tests a small device placed near your spinal cord (called epidural spinal cord stimulation) to see if it can help improve leg movement and stiffness in people with adrenomyeloneuropathy (AMN). If you have AMN and trouble walking due to leg stiffness, this study may explore a new option for you.
Beijing, Beijing MunicipalityAges 22–50 - NCT06796972Recruiting
Emotional impact of fetal surgery for spina bifida
This study looks at how parents make decisions about fetal surgery for spina bifida (myelomeningocele) and how they feel afterward. It aims to understand the emotional and psychological effects to better support families.
Paris, ParisAges 18 years+ - NCT06797024Recruiting
Study of JY231 injection for tough nerve immune disorders
This trial tests a new injection called JY231 for people with certain hard-to-treat nerve and immune disorders that haven't improved with standard treatments. It aims to see if this experimental therapy can help control the disease when other options have failed.
Wuhan, HubeiAges 18–75 - NCT06797154Recruiting
Stroke recovery study: wrist sensor to boost arm use
This study tests a wrist-worn sensor that vibrates to remind you to use your weaker arm. It's designed for people who had a stroke 1 to 6 months ago and have some arm weakness, to help them use their affected arm more during daily activities.
Boston, MassachusettsAges 18–85 - NCT06797219Recruiting
Light therapy device study for newborns with severe brain bleeding
This trial tests a light therapy device in newborns who had a severe form of brain bleeding (intraventricular hemorrhage grade 3 or 4) within the first month of life. The goal is to see if this non-invasive treatment may help improve recovery.
Newark, New JerseyAges birth–1 month - NCT06797284Recruiting
Light, electrical, and magnetic therapy for sleep issues
This study tests if light, electrical, or magnetic treatments can help people with insomnia, narcolepsy, or REM sleep behavior disorder improve their sleep-wake problems. It compares these gentle brain stimulation methods to understand which works best.
Suzhou, JiangsuAges 8–75 - NCT06797661Recruiting
Brain lesion blood flow study before surgery
This study looks at how blood flow in the brain changes when there is a mass that can be removed with surgery. You would join before any treatment, which helps doctors understand the link between the brain lesion and blood vessel function.
BrusselsAges 18–90 - NCT06797752Recruiting
Stellate ganglion block and retina blood flow study
This trial looks at how a nerve block (stellate ganglion block) affects blood flow in the retina. It may help people who already get this block for conditions like complex regional pain syndrome understand eye effects.
Dallas, TexasAges 18 years+ - NCT06798012RecruitingPhase 2
TAK-411 for adults with CIDP
This study tests a new investigational drug called TAK-411 for adults with chronic inflammatory demyelinating polyneuropathy (CIDP). It is for people who have already responded to immunoglobulin therapy and are on a stable dose.
La Jolla, CaliforniaAges 18 years+
Common questions
- How many brain & nervous system clinical trials are recruiting?
- Clin2 is tracking 12,462 recruiting neurology studies from the U.S. registry right now, out of 19,649 we cover in this area in total.
- What does “Brain & nervous system” cover here?
- Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We group each study into brain & nervous system based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a brain & nervous system trial near me?
- Use the search to filter brain & nervous system studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.