Neurology
Brain & nervous system clinical trials
Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We’re tracking 12,462 recruiting studies in this area right now.
By phase
- Not applicable9,797
- Phase 2786
- Phase 1574
- Phase 3538
- Phase 4342
- Phase 1/Phase 2304
- Phase 2/Phase 3121
Top conditions
- Stroke854
- Parkinson Disease424
- Multiple Sclerosis342
- Alzheimer Disease340
- Dementia226
- Ischemic Stroke199
- Epilepsy196
- Obstructive Sleep Apnea155
- Spinal Cord Injuries154
- Insomnia152
- Traumatic Brain Injury152
- Sarcopenia148
- Acute Ischemic Stroke141
- Cerebral Palsy130
- Mild Cognitive Impairment129
- Pain Management114
- Migraine113
- Amyotrophic Lateral Sclerosis107
Leading sponsors
- Beijing Tiantan Hospital134
- Riphah International University125
- Assistance Publique - Hôpitaux de Paris112
- Mayo Clinic99
- Xuanwu Hospital, Beijing95
- VA Office of Research and Development93
- Hospices Civils de Lyon79
- Johns Hopkins University70
- National Taiwan University Hospital70
- Cairo University63
Where studies are running
- California675
- Massachusetts301
- New York292
- Florida277
- Texas267
- Maryland244
- Arizona216
- Alabama211
- Illinois193
- Pennsylvania177
Recruiting studies12,460 total
- NCT06786676RecruitingPhase 1
Safety study of AS-S603 in healthy volunteers
This trial tests a new drug called AS-S603 in healthy volunteers to see if it is safe and how the body processes it. It is an early-phase study for people of Korean or Caucasian background.
SeoulAges 19–85 - NCT06786858Recruiting
Hand exoskeleton training for stroke recovery
This study tests whether a robotic hand device (exoskeleton) can help people who had a stroke more than 6 months ago improve hand movement. It may benefit those who still have some hand function but struggle to open their affected hand.
Washington D.C., District of ColumbiaAges 21 years+ - NCT06787677Recruiting
SPG pulsed radiofrequency for chronic cluster headache
This trial tests a treatment called sphenopalatine ganglion (SPG) pulsed radiofrequency for people with chronic cluster headache. It uses short bursts of energy to calm a nerve cluster in the face that is linked to the pain, and may help when standard medicines like verapamil or lithium haven't worked.
Beijing, Beijing MunicipalityAges 18 years+ - NCT06788119Recruiting
Smartphone tool for facing fears in anxiety
This study tests a smartphone tool called SYMPTOMS-JIT to help people with anxiety disorders face their fears in real life. It might be a good option if you have a specific phobia, agoraphobia, panic disorder, or social phobia and want to try a new, guided approach.
Castellon, CastellónAges 18 years+ - NCT06788288Recruiting
Massage chairs and sleep quality study
This study tests whether using a massage chair over several weeks can help improve sleep in people who have trouble sleeping. You may qualify if you have poor sleep and are otherwise healthy.
Trikala, ThessalyAges 18–45 - NCT06788743Recruiting
Sevoflurane vs. propofol for preventing confusion after surgery in older diabetics
This trial compares two common anesthesia drugs (sevoflurane gas vs. propofol injection) to see which one lowers the risk of confusion or delirium after surgery in older adults with diabetes. It aims to find a safer way to give anesthesia for your operation.
Xi’an, ShanxiAges 60 years+ - NCT06788886Recruiting
Breathing practice for brain and mental health in cancer and other illnesses
This study tests a simple breathing practice to see if it can improve brain health and mental well-being for people with cancer, multiple sclerosis, or their caregivers. You will do light exercises and answer questionnaires, and some participants will also have an MRI brain scan.
Rochester, MinnesotaAges 18–85 - NCT06788977Recruiting
Migraine treatment in pregnancy with a nerve stimulation device
This trial tests if a device that gently stimulates a nerve on your forehead can safely treat migraines during pregnancy. You'll use the device at home and track your headaches via text or email.
Darien, ConnecticutAges 18–44 - NCT06789250Recruiting
Online therapy for mental health and alcohol use issues
This trial tests an internet-based cognitive behavioral therapy program designed for people who struggle with both mental health symptoms (like depression or anxiety) and problematic alcohol use. The goal is to see if this approach can help improve both issues at the same time, conveniently from home.
LinköpingAges 18 years+ - NCT06789783RecruitingPhase 2/Phase 3
Lithium treatment for Cornelia de Lange syndrome
This trial tests whether lithium can help people with Cornelia de Lange syndrome (CdLS) who have a confirmed NIPBL gene mutation. It might improve their daily life and overall well-being.
Milan, MIAges 4 years+ - NCT06789770Recruiting
Nasal vs mouth breathing during drug-induced sleep
This study compares how breathing through the nose versus mouth affects sleep, using both natural and medication-induced sleep. It may help people with sleep apnea understand their breathing patterns better.
Philadelphia, PennsylvaniaAges 18 years+ - NCT06790394RecruitingPhase 1
Test-Retest PET Scan Study for Heart Amyloidosis
This study uses a special PET scan tracer to see how consistent the images are in people with heart amyloidosis (a buildup of abnormal protein in the heart) and in people without the condition. The goal is to improve diagnosis and monitoring.
LondonAges 40 years+ - NCT06790914Recruiting
Testing a method to reduce pain after lung cancer surgery
This study looks at whether a special care during surgery can reduce extra sensitivity to pain (called hyperalgesia) after a keyhole lung cancer operation. It aims to find better ways to make recovery less painful.
Fujian, FuzhouAges 18 years+ - NCT06790979Recruiting
Sleep patterns and recovery after traumatic brain injury
This study uses a wearable device to track sleep patterns in people who have had a traumatic brain injury (TBI). It aims to see how sleep relates to recovery, which could help improve care after a head injury.
Yinchuan, NingxiaAges 18–60 - NCT06791356Recruiting
Better Sleep for Older African Americans
This study tests a type of talk therapy for insomnia called CBT-I, done over Zoom. It's for older African Americans who have had trouble sleeping for at least three months.
Newark, New JerseyAges 60 years+ - NCT06791551Recruiting
Non-drug therapy before heart surgery to protect the brain
This study tests whether a simple, non-drug, non-surgical program before heart surgery can help protect your brain. It is for people with heart disease who are at higher risk for problems like stroke after surgery.
Beijing, Beijing MunicipalityAges 18–80 - NCT06791902Recruiting
Adaptive brain stimulation for walking problems in Parkinson's
This study tests a new type of deep brain stimulation (DBS) that automatically adjusts to your walking or balance issues. It uses your brain's own signals to improve movement.
Lausanne, Canton of VaudAges 18 years+ - NCT06792045Recruiting
Predicting tongue blockage during sleep in children
This study uses a special camera during sleep to see if the tongue is blocking the airway in children with sleep-disordered breathing. It may help doctors better understand why some children still have trouble breathing after tonsil surgery.
BrusselsAges 6–17 - NCT06792201Recruiting
Sarcopenia study in women at different life stages
This trial looks at muscle loss (sarcopenia) in women who are pre-menopause or post-menopause, and whether hormone replacement therapy affects it. It aims to understand how muscle health changes over a woman's life.
BolognaAges 18–65 - NCT06792383Recruiting
Psychological and psychiatric assessment before epilepsy surgery
This study evaluates psychological and psychiatric well-being in adults with drug-resistant epilepsy who are being considered for surgery. It aims to understand factors that may affect outcomes and patient experience.
MilanAges 18 years+ - NCT06792877Recruiting
Mindfulness for thinking in early Alzheimer's
This study tests if mindfulness training can help protect thinking and memory in early-stage Alzheimer's disease. It compares mindfulness to other activities to see if it slows down memory loss.
Boston, MassachusettsAges 50–100 - NCT06793332RecruitingPhase 2
Ivonescimab and Trodelvy for breast cancer with brain metastases
This trial tests two drugs (Ivonescimab and a Trop2 ADC) for people with triple-negative breast cancer that has spread to the brain. It aims to see if this combination can shrink brain tumors and help patients live longer.
Shanghai, Shanghai MunicipalityAges 18–70 - NCT06793527Recruiting
Pain relief methods for laparoscopic bariatric surgery
This trial compares three different pain relief methods during weight-loss surgery: a nerve block, a lidocaine drip, and a targeted injection near the celiac plexus. The goal is to find which approach works best with fewer side effects.
Krakow, Lesser Poland VoivodeshipAges 18–75 - NCT06793735Recruiting
Virtual reality app for memory and thinking problems
This trial tests a virtual reality app you can use at home to help with early memory or thinking problems. It may be an option if you have mild cognitive impairment or notice your thinking is slowing down.
Messina, ItalyAges 40–80
Common questions
- How many brain & nervous system clinical trials are recruiting?
- Clin2 is tracking 12,462 recruiting neurology studies from the U.S. registry right now, out of 19,649 we cover in this area in total.
- What does “Brain & nervous system” cover here?
- Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We group each study into brain & nervous system based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a brain & nervous system trial near me?
- Use the search to filter brain & nervous system studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.