Neurology
Brain & nervous system clinical trials
Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We’re tracking 12,473 recruiting studies in this area right now.
By phase
- Not applicable9,815
- Phase 2785
- Phase 1573
- Phase 3534
- Phase 4343
- Phase 1/Phase 2304
- Phase 2/Phase 3119
Top conditions
- Stroke856
- Parkinson Disease424
- Alzheimer Disease341
- Multiple Sclerosis341
- Dementia228
- Ischemic Stroke199
- Epilepsy195
- Obstructive Sleep Apnea155
- Traumatic Brain Injury154
- Insomnia152
- Spinal Cord Injuries151
- Sarcopenia149
- Acute Ischemic Stroke141
- Cerebral Palsy130
- Mild Cognitive Impairment129
- Migraine113
- Pain Management112
- Amyotrophic Lateral Sclerosis107
Leading sponsors
- Beijing Tiantan Hospital135
- Riphah International University125
- Assistance Publique - Hôpitaux de Paris112
- Mayo Clinic98
- Xuanwu Hospital, Beijing95
- VA Office of Research and Development92
- Hospices Civils de Lyon79
- Johns Hopkins University71
- National Taiwan University Hospital70
- University of Minnesota63
Where studies are running
- California674
- Massachusetts306
- New York293
- Florida277
- Texas270
- Maryland245
- Arizona213
- Alabama212
- Illinois193
- Pennsylvania177
Recruiting studies12,471 total
- NCT07096674RecruitingPhase 2
Long-term study of ORX750 for narcolepsy and idiopathic hypersomnia
This trial is for people who have already completed the main CRYSTAL-1 study of ORX750. It tests the long-term safety and effects of the drug, so you can continue treatment if it was helping you.
Auburn, AlabamaAges 18–65 - NCT07096687Recruiting
Cooling treatment for acute ischemic stroke
This trial tests whether lowering body temperature (targeted temperature management) can help people who have had a stroke within the last 48 hours. It focuses on strokes caused by a blockage in a specific part of the brain's blood supply, and aims to see if cooling can reduce brain damage.
Bologna, BolognaAges 18 years+ - NCT07096700Recruiting
VR and wearable brace for multiple sclerosis rehabilitation
This trial tests whether combining virtual reality exercises with a leg brace can help people with multiple sclerosis improve their walking and balance. If you have mild to moderate disability and can use the Exoband brace, you may be eligible.
Bologna, BolognaAges 18–65 - NCT07097298Recruiting
Empathy and compassion study for Parkinson's patients and caregivers
This study explores empathy and self-compassion in people with Parkinson's disease and their caregivers. If you have mild to moderate Parkinson's and a caregiver at home, you and your caregiver may join together to help researchers understand how to better support both of you.
LuganoAges 50–80 - NCT07097701RecruitingPhase 3
Comparing two forms of mexiletine for non-dystrophic myotonias
This trial compares a new extended-release (PR) form of mexiletine to the immediate-release (IR) form in people with non-dystrophic myotonias. The goal is to see if the longer-acting version works as well or better with fewer side effects.
LeuvenAges 16 years+ - NCT07097792Recruiting
Concussion recovery support program for headaches
This study tests a support program for young people who have had a concussion and are still having headaches. It aims to help them recover and feel better.
Seattle, WashingtonAges 18–29 - NCT07098728Recruiting
Levetiracetam vs Phenobarbital for prolonged seizures in children
This trial compares two antiseizure medicines, levetiracetam and phenobarbital, to see which one works better for children whose prolonged seizures (lasting several minutes) do not stop after two doses of a rescue medicine called benzodiazepine.
Yangon, YangonAges 1 month–12 years - NCT07099599Recruiting
Image test for blood flow after stroke treatment
This trial uses a special imaging technique to check if blood flow has fully returned to the brain after a stroke clot is removed. It aims to improve understanding of how well the brain's tiny blood vessels are working after treatment.
Cincinnati, OhioAges 18 years+ - NCT07099651Recruiting
Social understanding in spinocerebellar ataxia
This study looks at how people with certain genetic types of spinocerebellar ataxia (a condition that affects movement and coordination) understand social situations. It aims to see if there are differences in social thinking compared to people without the condition.
AngersAges 18–100 - NCT07099911Recruiting
Electrical stimulation and blood sugar control after spinal cord injury
This study tests whether a type of electrical stimulation on leg muscles can help control blood sugar levels in people with spinal cord injury. It compares results to those without injury to see if this treatment might improve health.
Bath, United KingdomAges 18 years+ - NCT07100119RecruitingPhase 1
Study of LY4256984 for people with sporadic ALS
This trial tests a new medicine called LY4256984 for people with sporadic ALS (ALS not caused by a known genetic mutation). The goal is to see if the drug is safe and how it affects the body. It may offer a new treatment option for people recently diagnosed with ALS.
LeuvenAges 18–75 - NCT07100600RecruitingPhase 2
Targeted drug with or without radiation for HER2-positive breast cancer brain tumors
This trial tests whether adding radiation therapy to a targeted cancer drug (trastuzumab rezetecan) is better than the drug alone for women with HER2-positive breast cancer that has spread to the brain. If you have untreated brain tumors from this type of breast cancer, this study aims to find the best way to stop them from growing.
Zhengzhou, HenanAges 18 years+ - NCT07101250RecruitingPhase 4
Study of acetazolamide before laparoscopic hysterectomy
This trial tests a medication called acetazolamide given before surgery to see if it can help prevent shoulder pain after a laparoscopic hysterectomy. If you are a woman scheduled for this type of hysterectomy, you may be able to join.
Greenville, South CarolinaAges 21–65 - NCT07101302Recruiting
App-based insomnia help for cancer survivors
This trial tests a smartphone app designed to help cancer survivors improve their sleep. If you have trouble sleeping and live in Canada, this app-based program could help you manage insomnia without needing to visit a clinic.
St. John's, Newfoundland and LabradorAges 18 years+ - NCT07101523Recruiting
Using technology to promote healthy lifestyles
This trial uses technology to help adolescents with intellectual disabilities adopt healthier habits like exercise and good nutrition. It aims to find out if using smartphones can make it easier to stay active and eat well.
Seville, SpainAges 4–30 - NCT07101796Recruiting
Mood and personality in sleep apnea treatment
This study looks at how mood and personality traits affect treatment adherence in people with suspected or confirmed sleep apnea. It may help tailor support for better treatment outcomes.
Beijing, Beijing MunicipalityAges 18–70 - NCT07101939RecruitingPhase 2
Studying a medicine to preserve muscle during weight loss
This trial tests a new medicine, (S)-pindolol benzoate, given along with semaglutide (Ozempic/Wegovy). The goal is to see if it helps people lose mostly fat instead of muscle while on a weight loss program.
BelgradeAges 18–75 - NCT07102342RecruitingPhase 1/Phase 2
Cell therapy for Parkinson's disease
This trial tests a new cell treatment for Parkinson's disease. It involves injecting special cells into the brain to see if they can safely replace damaged cells and improve symptoms. It might help people who have had Parkinson's for several years and still respond well to medication.
New York, New YorkAges 30–75 - NCT07102394RecruitingPhase 1
Testing talimogene laherparepvec for skin bumps in adults with NF1
This trial tests a drug called IMLYGIC (talimogene laherparepvec) to see if it is safe and tolerable for treating skin bumps (cutaneous neurofibromas) in adults with NF1. The drug is injected directly into the bumps, and the study will check if it can shrink them or improve symptoms.
Baltimore, MarylandAges 18 years+ - NCT07102446Recruiting
Opioid safety program for chronic pain patients without cancer
This trial tests a program to help manage opioid use safely for people with chronic non-cancer pain. If you take opioids for long-term pain and do not have cancer, this study may help improve your care.
Seoul, SeoulAges 19–79 - NCT07102927Recruiting
Virtual reality training for stroke patients with neglect
This trial tests whether virtual reality exercises can help people with right-brain stroke overcome 'neglect' (trouble noticing things on their left side). It aims to improve daily function and quality of life.
SeoulAges 19–99 - NCT07103044Recruiting
Early learning program for children with language delays
This study tests a program that helps teachers support language and early reading skills in preschool children with language delays or disorders. It compares children who receive language services with those developing typically.
Baltimore, MarylandAges 3.8 years–5.4 years - NCT07103356Recruiting
Water pitcher filter to reduce arsenic in well water
This study gives eligible New Hampshire residents a special water pitcher filter that helps remove arsenic from well water. The study team will check if the filter works well over time and if people can use it easily at home.
Lebanon, New HampshireAges 18 years+ - NCT07103590Recruiting
Comparing two plates for fixing jaw angle fractures
This trial compares two types of metal plates used to fix a broken lower jaw angle. It aims to see which method works better and helps patients heal faster.
AlexandriaAges 20–50
Common questions
- How many brain & nervous system clinical trials are recruiting?
- Clin2 is tracking 12,473 recruiting neurology studies from the U.S. registry right now, out of 19,792 we cover in this area in total.
- What does “Brain & nervous system” cover here?
- Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We group each study into brain & nervous system based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a brain & nervous system trial near me?
- Use the search to filter brain & nervous system studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.