Neurology
Brain & nervous system clinical trials
Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We’re tracking 12,487 recruiting studies in this area right now.
By phase
- Not applicable9,830
- Phase 2786
- Phase 1573
- Phase 3532
- Phase 4343
- Phase 1/Phase 2304
- Phase 2/Phase 3119
Top conditions
- Stroke855
- Parkinson Disease423
- Alzheimer Disease341
- Multiple Sclerosis341
- Dementia229
- Ischemic Stroke200
- Epilepsy195
- Obstructive Sleep Apnea155
- Traumatic Brain Injury154
- Insomnia153
- Spinal Cord Injuries151
- Sarcopenia149
- Acute Ischemic Stroke141
- Cerebral Palsy131
- Mild Cognitive Impairment129
- Migraine113
- Pain Management113
- Amyotrophic Lateral Sclerosis107
Leading sponsors
- Beijing Tiantan Hospital135
- Riphah International University125
- Assistance Publique - Hôpitaux de Paris112
- Mayo Clinic99
- Xuanwu Hospital, Beijing94
- VA Office of Research and Development92
- Hospices Civils de Lyon79
- Johns Hopkins University71
- National Taiwan University Hospital69
- University of Minnesota63
Where studies are running
- California673
- Massachusetts306
- New York293
- Florida278
- Texas270
- Maryland245
- Alabama213
- Arizona212
- Illinois193
- Pennsylvania177
Recruiting studies12,485 total
- NCT07248995Recruiting
Ultrasound to set breathing support in brain injury patients with lung issues
This trial tests if chest and head ultrasound can help doctors adjust the breathing machine (PEEP) for patients with both a severe brain injury and a serious lung condition called ARDS. The goal is to improve care without harming the brain.
ThessalonikiAges 18 years+ - NCT07249060Recruiting
Interferon levels in cancer and autoimmune disease patients
This study looks at a protein called interferon in the blood of people with cancer who are starting immunotherapy, and people with certain autoimmune diseases (such as lupus, Sjögren's syndrome, scleroderma, or inflammatory myopathy). The goal is to compare interferon patterns and better understand immune responses.
Pamplona, NavarreAges 18 years+ - NCT07249632RecruitingPhase 3
Study of Telitacicept for Eye Muscle Weakness from Myasthenia Gravis
This trial tests a new drug, telitacicept, for people with myasthenia gravis that only affects the eyes (ocular myasthenia gravis). The goal is to see if it can improve symptoms like droopy eyelids or double vision.
Beijing, Beijing MunicipalityAges 12–80 - NCT07249918Recruiting
Wearable devices for dementia care in rural Taiwan
This trial tests if wearable devices can help monitor and improve behavioral symptoms like agitation, depression, or sleep problems in people with Alzheimer's or mild cognitive impairment. It also involves their caregivers.
Beigang, YunlinAges Any age - NCT07250035RecruitingPhase 3
Chinese herb trial for brain bleed linked to amyloid angiopathy
This trial tests a traditional Chinese medicine called Jiedu Huayu to see if it helps people recover from a brain bleed caused by a condition where proteins build up in blood vessel walls (cerebral amyloid angiopathy). The goal is to improve outcomes without surgery.
BeijingAges 50–90 - NCT07250230Recruiting
Nicotine patch for pain after lung surgery in male smokers
This study tests if a high-dose nicotine patch worn before and after lung surgery can reduce pain in men who smoke but are quitting for the procedure. It aims to help manage pain during recovery.
Zhengzhou, HenanAges 18–75 - NCT07250672Recruiting
3D video training for Parkinson's movement
This trial tests if watching personalized 3D videos of movements can help improve walking and other skills in people with Parkinson's. It involves using a special viewer to watch actions that match your own needs.
Bolu, BoluAges 50–85 - NCT07250750RecruitingPhase 1/Phase 2
IM-101 for generalized and ocular myasthenia gravis
This study tests a new medicine called IM-101 in people with myasthenia gravis (MG), a muscle weakness condition. It aims to see if it can safely help manage symptoms.
Altamonte Springs, FloridaAges 18–74 - NCT07250958Recruiting
Testing dome-only coiling for severe aneurysm bleeding
This trial tests a specific way of treating a brain aneurysm that has caused a severe bleed (subarachnoid hemorrhage). Instead of coiling the whole aneurysm, doctors will only coil the dome part. The goal is to see if this simpler approach helps patients who are very sick from the bleeding.
Louisville, KentuckyAges 18 years+ - NCT07251023RecruitingPhase 3
Testing a new drug for Alzheimer's dementia
This study tests whether a new drug called Latrepirdine (DMB-I) is safe and effective for people with mild to moderate Alzheimer's dementia. It may help slow cognitive decline when added to current treatment or used alone.
Kazan'Ages 60–90 - NCT07681401Recruiting
Financial help for dementia caregivers
This study provides financial counseling to family or friends who care for someone with Alzheimer's disease or related dementias. It tests if this support helps caregivers manage stress and finances.
Salt Lake City, UtahAges 25–55 - NCT07680725Recruiting
Bottle breathing exercise for Parkinson's: muscle strength and balance
This trial tests if a simple breathing exercise using a bottle can strengthen the muscles you use to breathe and improve your balance. It may help people with Parkinson's who can walk on their own.
Istanbul, MaltepeAges 18–75 - NCT07054801RecruitingPhase 2
Testing lidocaine and steroids for headache after bleeding stroke
This study tests whether giving two medicines (lidocaine and methylprednisolone) directly into the artery during a routine brain vessel procedure can help relieve headaches caused by a bleeding stroke. It may help find a new treatment for this type of headache.
San Francisco, CaliforniaAges 18 years+ - NCT06459635Recruiting
Migraine attack prediction study using smartphone tracking
This study uses a smartphone app or device to track your body signals and predict when a migraine attack is about to start. It is designed for people with frequent (10–14 days per month) migraines.
Madrid, MadridAges 18–65 - NCT07682090Recruiting
Nerve stimulation for fibromyalgia pain
This study tests a gentle nerve stimulation device worn near your ear to see if it can reduce fibromyalgia pain and improve how your body handles stress. It is a non-invasive treatment option that you receive while continuing your regular medications.
Rome, LazioAges 18–70 - NCT02390518RecruitingPhase 1
Tested different radiation doses for brain metastases
This Phase 1 study tests how to safely give focused radiation (SRS) at different doses to people with brain metastases. It aims to find a dose level that works well while limiting side effects.
Salt Lake City, UtahAges 18 years+ - NCT07681973Recruiting
Smell training for loss of smell in sinus patients
This study tests whether smell training can improve your sense of smell and affect your immune system. It is for people with chronic sinus inflammation and nasal polyps who have lost their sense of smell.
Cleveland, OhioAges 18 years+ - NCT05359653RecruitingPhase 1/Phase 2
Clemastine to study MRI changes in relapsing MS
This early-phase study tests whether clemastine (a drug being studied for “myelin repair”) changes how MS looks on special MRI scans. It may help researchers understand if the treatment supports restoring nerve covering in people with relapsing-remitting MS.
San Francisco, CaliforniaAges 18–55 - NCT07095920Recruiting
Brain stimulation for arm recovery after stroke
This trial tests a brain stimulation device (Brain Q) to help improve arm and hand movement in people who had a stroke 6 months to 5 years ago. The goal is to see if it can boost recovery beyond standard therapy.
Jacksonville, FloridaAges 18–80 - NCT07680335Recruiting
Blood test to help diagnose Alzheimer's earlier
This study is testing whether a simple blood test can help doctors diagnose Alzheimer's disease earlier and more accurately. It's for people who are having memory or thinking problems and are visiting a memory clinic.
Amsterdam, North HollandAges 55 years+ - NCT06459648Recruiting
Can anti-CGRP antibodies prevent chronic migraine?
This study tests a new treatment (anti-CGRP antibodies) to prevent migraine attacks from becoming chronic. It looks at whether we can predict who will respond best, aiming to find better long-term control for people with frequent or chronic migraine.
Zaragoza, AragonAges 18–65 - NCT07680842Recruiting
Non-invasive ultrasound for drug-resistant epilepsy
This study tests a non-invasive focused ultrasound treatment for people with epilepsy that doesn't respond to medications. The goal is to see if this gentle ultrasound can reduce seizures without surgery.
San Francisco, CaliforniaAges 21–65 - NCT07546409Recruiting
Do ketones help thinking in older adults with prediabetes?
This study looks at whether a supplement called ketones can improve thinking and memory in older adults who have prediabetes but not diabetes or memory problems. You will take the supplement, have brain scans, and complete thinking tests.
Birmingham, AlabamaAges 60–75 - NCT05566301Recruiting
Study of blood thinner response after carotid stent
This study looks at how well clopidogrel works in adults who receive a carotid artery stent and are on dual blood thinners. It may help doctors understand why some people don’t get the expected benefit and improve treatment after stenting.
San Donato Milanese, MilanAges 18 years+
Common questions
- How many brain & nervous system clinical trials are recruiting?
- Clin2 is tracking 12,487 recruiting neurology studies from the U.S. registry right now, out of 19,851 we cover in this area in total.
- What does “Brain & nervous system” cover here?
- Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We group each study into brain & nervous system based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a brain & nervous system trial near me?
- Use the search to filter brain & nervous system studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.