Neurology
Brain & nervous system clinical trials
Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We’re tracking 12,487 recruiting studies in this area right now.
By phase
- Not applicable9,830
- Phase 2786
- Phase 1573
- Phase 3532
- Phase 4343
- Phase 1/Phase 2304
- Phase 2/Phase 3119
Top conditions
- Stroke855
- Parkinson Disease423
- Alzheimer Disease341
- Multiple Sclerosis341
- Dementia229
- Ischemic Stroke200
- Epilepsy195
- Obstructive Sleep Apnea155
- Traumatic Brain Injury154
- Insomnia153
- Spinal Cord Injuries151
- Sarcopenia149
- Acute Ischemic Stroke141
- Cerebral Palsy131
- Mild Cognitive Impairment129
- Migraine113
- Pain Management113
- Amyotrophic Lateral Sclerosis107
Leading sponsors
- Beijing Tiantan Hospital135
- Riphah International University125
- Assistance Publique - Hôpitaux de Paris112
- Mayo Clinic99
- Xuanwu Hospital, Beijing94
- VA Office of Research and Development92
- Hospices Civils de Lyon79
- Johns Hopkins University71
- National Taiwan University Hospital69
- University of Minnesota63
Where studies are running
- California673
- Massachusetts306
- New York293
- Florida278
- Texas270
- Maryland245
- Alabama213
- Arizona212
- Illinois193
- Pennsylvania177
Recruiting studies12,485 total
- NCT07283159RecruitingPhase 2
Tenecteplase plus a second drug for stroke recovery
This study tests whether giving a second drug (urinary kallidinogenase) after the clot-busting drug tenecteplase can help people with moderate to severe ischemic strokes recover better. It is for patients who started treatment within 4.5 hours of symptoms.
ShenyangAges 18 years+ - NCT07283289Recruiting
Obstructive sleep apnea in patients with PAD
This study looks at how common obstructive sleep apnea is in people with peripheral artery disease (PAD). Participants will have a sleep test as part of their regular care.
Toulon, VarAges 18 years+ - NCT07284082Recruiting
How Does Menopause and HIV Affect Heart Health in Women?
This study looks at how menopause and HIV together might affect a woman's risk for heart disease. If you are a woman with HIV and are either premenopausal, perimenopausal, or postmenopausal, the researchers want to see if the combination of HIV and menopause creates a higher risk.
San Francisco, CaliforniaAges 18 years+ - NCT07284264Recruiting
Early Alzheimer's detection study using digital tools
This study uses a digital tool to help detect early signs of Alzheimer's disease in people aged 50 and older. It aims to find high-risk individuals who may benefit from early monitoring.
BeijingAges 50 years+ - NCT07284290RecruitingPhase 4
Brain imaging, thinking, and medication study for Lewy body dementia
This study looks at how brain changes affect attention and thinking in people with Lewy body dementia. It includes brain scans, an EEG, and a medication option to see if it helps with symptoms.
Richmond, VirginiaAges 50–89 - NCT07284732Recruiting
Ear nerve stimulation for consciousness disorders
This trial tests whether a gentle electrical stimulation on the ear can help people with disorders of consciousness, like a vegetative or minimally conscious state. It aims to see if this noninvasive treatment can improve brain function and awareness.
Guangzhou, GuangdongAges 18–70 - NCT07284719Recruiting
Focused Ultrasound for Parkinson's Tremor
This trial tests a non-invasive treatment called MR-guided focused ultrasound (MRgFUS) to reduce severe tremor in Parkinson's disease. It uses sound waves to target the brain area causing the shaking, without surgery.
AarhusAges 50–80 - NCT07284784RecruitingPhase 2/Phase 3
Buntanetap for Parkinson's disease study
This trial tests an investigational drug called buntanetap in people with Parkinson's disease. It aims to see if the drug can improve symptoms. There are two groups: those who've taken buntanetap before (Cohort 1) and those with a deep brain stimulator (DBS) implant for at least a year (Cohort 2).
Birmingham, AlabamaAges 40–85 - NCT07284797RecruitingPhase 1
Safety study for autoimmune disease and healthy volunteers
This trial is testing an experimental drug for safety in people with certain autoimmune diseases—like myositis, scleroderma, or Sjögren's disease—as well as in healthy volunteers. It aims to find out if the drug is safe enough to study further.
MelbourneAges 18–75 - NCT07284823Recruiting
Cionic sleeve study for walking problems in Parkinson's
This trial tests a wearable sleeve that uses gentle electrical signals to help improve walking in people with Parkinson's disease. It aims to see if the sleeve is safe and easy to use.
Carlsbad, CaliforniaAges 22–75 - NCT07285187Recruiting
Vein congestion and confusion after heart surgery trial
This trial looks at how blood backing up in veins after heart surgery might relate to delirium (sudden confusion). It uses a special ultrasound to check vein blood flow and then watches for confusion afterward.
Yangzhou, JiangsuAges 18 years+ - NCT07285226Recruiting
Creatine for muscle loss in older adults
This trial tests whether taking creatine HCl can help older adults with muscle loss (sarcopenia) improve muscle strength. If you are over 60 and have weak grip strength, this study might be for you.
BelgradeAges 60 years+ - NCT07285356Recruiting
Surgical gloves to prevent nerve damage from oxaliplatin
This trial tests whether wearing special surgical gloves during oxaliplatin chemotherapy can help prevent nerve damage (numbness or tingling) in people with advanced colon cancer.
São Paulo, São PauloAges 18 years+ - NCT07285720Recruiting
Language Development in Williams Syndrome
This study looks at how children and adults with Williams syndrome learn language. Researchers want to understand how sounds and word patterns affect language skills in this condition.
AmiensAges 6 years+ - NCT07285837Recruiting
Intensive arm rehab for kids with cerebral palsy
This study tests an intensive rehabilitation program for the upper limb (arm and hand) in children and teens with cerebral palsy. It aims to improve arm function and may help your child gain more control and independence.
Saint-Fargeau-Ponthierry, Île-de-France RegionAges 3–17 - NCT07285954Recruiting
Mindful walking study for brain health
This study tests whether a mindful walking program (audio-guided walks) can help people with brain conditions like multiple sclerosis, Parkinson's, or Alzheimer's feel more resilient. If you join, you will be randomly assigned to the walking program or a control group, and you'll wear a Fitbit and do some in-person brain tests.
Urbana, IllinoisAges 18–110 - NCT07286565Recruiting
Remote motor development study for early-diagnosed DMD or SMA
This study remotely tracks motor development in children with Duchenne muscular dystrophy or spinal muscular atrophy who were diagnosed at birth or before symptoms started. It aims to see if early monitoring helps improve long-term care and outcomes.
LiègeAges 4 months+ - NCT07286734Recruiting
Ultrasound study of radial nerve in arm fracture with nerve injury
This study uses ultrasound and nerve tests to examine the radial nerve in people who have a broken upper arm bone (humeral shaft fracture) and also have radial nerve palsy (weakness or paralysis on the back of the hand/forearm). The goal is to better understand how the nerve is affected by the fracture.
Istanbul, KarsAges 18 years+ - NCT07287059Recruiting
Wearable robot and virtual reality for hand recovery after stroke
This study tests if combining a wearable robotic glove with virtual reality exercises can help improve hand function in people who have had a stroke. It may be a good fit if you have some movement in your hand and arm but need more help.
Istanbul, BeykozAges 30–60 - NCT07287124Recruiting
New fully implantable cochlear implant for severe hearing loss
This study tests a new type of cochlear implant that is completely placed under the skin, with no external parts. It is for adults with severe hearing loss who still struggle to hear even with hearing aids.
Englewood, ColoradoAges 18 years+ - NCT07287410Recruiting
Assessing thinking and daily life in dementia and MCI
This study looks at how dementia or mild cognitive impairment affects thinking, daily living, and mood. The goal is to better understand these conditions by doing careful assessments.
Messina, MEAges 50–86 - NCT07287189RecruitingPhase 2
SAT-3247 for boys with Duchenne muscular dystrophy
This trial tests a new daily pill called SAT-3247 for boys with Duchenne muscular dystrophy (DMD) who are still able to walk. The goal is to see if it can help slow muscle decline.
Los Angeles, CaliforniaAges 7–9 - NCT07287397RecruitingPhase 1/Phase 2
Testing VTx-002 for safety in ALS patients
This trial tests a new drug called VTx-002 to see if it is safe and tolerable for people with ALS. You may be able to join if you have had symptoms for less than 18 months and have a caregiver who can help.
Phoenix, ArizonaAges 18 years+ - NCT07287774Recruiting
Testing a new noise-reduction feature for hearing aids
This trial is testing a new computer program that helps hearing aids reduce background noise. It might make it easier for people with mild to moderate hearing loss to hear in noisy places.
West Lafayette, IndianaAges 18 years+
Common questions
- How many brain & nervous system clinical trials are recruiting?
- Clin2 is tracking 12,487 recruiting neurology studies from the U.S. registry right now, out of 19,851 we cover in this area in total.
- What does “Brain & nervous system” cover here?
- Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We group each study into brain & nervous system based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a brain & nervous system trial near me?
- Use the search to filter brain & nervous system studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.