Neurology
Brain & nervous system clinical trials
Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We’re tracking 12,407 recruiting studies in this area right now.
By phase
- Not applicable9,742
- Phase 2782
- Phase 1577
- Phase 3534
- Phase 4342
- Phase 1/Phase 2307
- Phase 2/Phase 3123
Top conditions
- Stroke843
- Parkinson Disease429
- Alzheimer Disease342
- Multiple Sclerosis342
- Dementia226
- Ischemic Stroke200
- Epilepsy197
- Obstructive Sleep Apnea156
- Spinal Cord Injuries153
- Insomnia152
- Sarcopenia150
- Traumatic Brain Injury150
- Acute Ischemic Stroke138
- Cerebral Palsy131
- Mild Cognitive Impairment129
- Migraine114
- Pain Management113
- Amyotrophic Lateral Sclerosis108
Leading sponsors
- Beijing Tiantan Hospital133
- Riphah International University125
- Assistance Publique - Hôpitaux de Paris112
- Mayo Clinic98
- Xuanwu Hospital, Beijing93
- VA Office of Research and Development92
- Hospices Civils de Lyon79
- Johns Hopkins University70
- National Taiwan University Hospital70
- University of Minnesota64
Where studies are running
- California680
- Massachusetts299
- New York292
- Florida274
- Texas267
- Maryland246
- Arizona213
- Alabama209
- Illinois189
- Pennsylvania177
Recruiting studies12,405 total
- NCT02535702Recruiting
Brain scan study to measure addiction biology
This study uses brain imaging (MRI) and tasks to better understand what’s happening in the brain in addiction. It may help researchers improve how addiction is studied and measured using brain-based methods.
Bethesda, MarylandAges 18 years+ - NCT03650829Recruiting
IVF baby study for pregnancies in Guangzhou
This study looks at babies born from IVF (assisted reproductive technology) pregnancies. It may help the hospital better understand outcomes for families who plan to deliver there and stay in Guangzhou for years.
Guangzhou, GuangdongAges Up to 18 years - NCT05878002Recruiting
Tests thinking, movement, and sleep after clot removal stroke
This study looks at thinking skills, body movement, and sleep patterns in adults after a specific type of stroke treated with a clot-removing procedure. It may help doctors better understand what changes happen after treatment and how to measure them.
RomeAges 18 years+ - NCT05724836Recruiting
Carotid artery narrowing treatment follow-up at clinic
This study follows people who are getting a procedure for carotid artery narrowing at the clinic. It aims to learn about outcomes after these treatments.
Jacksonville, FloridaAges 18 years+ - NCT05322239Recruiting
Brain stimulation study measuring resting brain activity
This trial tests how a specific brain stimulation method (theta burst stimulation) changes brain activity when you are resting. It may help researchers understand brain function changes, especially in people without certain mental or health risks.
Philadelphia, PennsylvaniaAges 18–60 - NCT05689866Recruiting
Study of bladder and sphincter symptoms in functional neurological disorders
This study looks at bladder and sphincter (urine control) symptoms in people with functional neurological disorders. It may help doctors understand what causes these symptoms and how to better treat them.
BobignyAges 18 years+ - NCT05401669Recruiting
Radial vs femoral access for brain artery imaging
This trial compares two ways doctors reach the blood vessels to do diagnostic brain angiography: through the wrist artery (radial) or the groin artery (femoral). It may help show which access route is safer or easier for people needing this brain blood vessel imaging.
Shanghai, ShangaiAges 18–80 - NCT02559752Recruiting
Computer brain testing during proton radiation for childhood tumors
This trial studies how children’s thinking and learning skills change while they receive proton beam radiation for a brain/spinal cord tumor. It uses computer-based cognitive tests to better understand brain effects during treatment, which may help future care.
St Louis, MissouriAges 4–21 - NCT02559804Recruiting
Study of nerve tumors in children affecting the spine canal
This study follows children and teens with certain nerve-cell tumors (like neuroblastoma) that involve the spinal canal. It collects information on how these tumors behave and how treatments and outcomes may differ, aiming to improve care over the long term.
GenovaAges Up to 18 years - NCT04956549Recruiting
Exercise program for early memory loss in African Americans
This study tests whether a structured exercise program can lower Alzheimer’s risk in older African American adults who have mild cognitive impairment (MCI). You’ll be placed by chance into an exercise group or a comparison group and attend group sessions for about a year.
Baton Rouge, LouisianaAges 60 years+ - NCT02142946Recruiting
Track balance and walking in people with MS
This study measures how well you can balance and walk over time. It may help researchers understand balance problems in multiple sclerosis and how they change with movement.
BaselAges 18–80 - NCT01668082Recruiting
Study brain tumor metabolism during planned brain surgery
This study looks at how brain tumors use energy (“metabolism”) during planned surgical removal. It may help researchers learn what makes tumors grow and how to improve future brain tumor treatments.
Dallas, TexasAges 18 years+ - NCT05483465RecruitingPhase 4
NAD supplement trial for brain blood vessel health in aging
This trial studies whether taking an NAD supplement can support brain blood vessel health as people age. Participants will be tested for brain and health changes and may help researchers understand how to keep the brain’s blood vessels healthier over time.
Oklahoma City, OklahomaAges 60–85 - NCT05265000Recruiting
Skin electrical stimulation for chronic low back pain
This study tests whether a gentle electrical treatment placed on the skin near the spine can reduce chronic low back pain. If you qualify, you’ll try the stimulation and complete several assessments over a day, so the team can measure any pain and function changes.
San Francisco, CaliforniaAges 21–85 - NCT03849963Recruiting
Brain imaging study of energy use and brain chemicals
This study uses MRI scans to measure how your brain uses energy and how certain brain chemicals are made. It’s for healthy adults and can help researchers understand normal brain chemistry and metabolism.
Dallas, TexasAges 18–60 - NCT04733599Recruiting
Spinal cord stimulation for long-term arm nerve pain
This trial tests whether a high-frequency spinal cord stimulator can reduce long-term nerve pain in the arm after a brachial plexus injury. It may help people whose pain has lasted at least 3 months despite standard treatments.
Jacksonville, FloridaAges 18 years+ - NCT04991831Recruiting
Registry study for Exablate thalamotomy in tremor-dominant Parkinson’s
This study follows people who are getting an Exablate procedure to treat medication-resistant, tremor-dominant Parkinson’s. It aims to track safety and outcomes in real-world care after the treatment is approved.
Miami, FloridaAges 30–99 - NCT04876742Recruiting
Wheat beer to help prevent confusion in ICU patients
This study tests whether drinking wheat beer can lower the risk of delirium, a sudden confusion that can happen in intensive care. If you’re at higher risk and can take the study drink safely, this could help you avoid or reduce delirium.
BaselAges 18 years+ - NCT05017051Recruiting
Testing brain function in adults with cerebral palsy
This trial measures how the brain and movement systems work in real-life (everyday) conditions. It may help researchers understand brain-related thinking and control problems in adults, and to compare them with healthy adults.
ClamartAges 18 years+ - NCT04577677Recruiting
Study brain effects of mild electrical stimulation
This study looks at how mild electrical stimulation to the brain affects brain activity. You might be eligible if you’re generally healthy and can safely receive this stimulation, with no conditions that increase risk.
Leuven, Vlaams-BrabantAges 18–40 - NCT04063514Enrolling by invitation
MRI-focused ultrasound study of blood-brain barrier in low-grade glioma
This study uses special imaging during routine MRI scans to check how well the blood-brain barrier lets substances pass in people with low-grade brain tumors. It may help researchers better measure and track treatment effects over time.
Santa Monica, CaliforniaAges 18 years+ - NCT04280458Recruiting
Intensive movement and thinking rehab for children with severe disabilities
This trial tests an intensive rehabilitation program to improve both movement abilities and daily function in children with severe, long-term disability due to early brain injury. It may help children gain better adaptive skills and independence through structured therapy.
Hyères, VarAges 4–13 - NCT04355195Recruiting
Preventing delirium after surgery in older patients
This trial tests a “care plan” meant to lower the risk of confusion (delirium) after surgery in people age 70 and older. If you qualify, you may receive additional prevention-focused care before and around your operation.
BerlinAges 70 years+ - NCT03840083Recruiting
Study how sleep affects learning in adults
This study looks at how getting good sleep changes learning in adults as they age. If you sleep regularly and don’t have certain sleep or brain/mental health conditions, you may be able to take part.
Amherst, MassachusettsAges 18–80
Common questions
- How many brain & nervous system clinical trials are recruiting?
- Clin2 is tracking 12,407 recruiting neurology studies from the U.S. registry right now, out of 19,276 we cover in this area in total.
- What does “Brain & nervous system” cover here?
- Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We group each study into brain & nervous system based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a brain & nervous system trial near me?
- Use the search to filter brain & nervous system studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.