Neurology
Brain & nervous system clinical trials
Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We’re tracking 12,407 recruiting studies in this area right now.
By phase
- Not applicable9,742
- Phase 2782
- Phase 1577
- Phase 3534
- Phase 4342
- Phase 1/Phase 2307
- Phase 2/Phase 3123
Top conditions
- Stroke843
- Parkinson Disease429
- Alzheimer Disease342
- Multiple Sclerosis342
- Dementia226
- Ischemic Stroke200
- Epilepsy197
- Obstructive Sleep Apnea156
- Spinal Cord Injuries153
- Insomnia152
- Sarcopenia150
- Traumatic Brain Injury150
- Acute Ischemic Stroke138
- Cerebral Palsy131
- Mild Cognitive Impairment129
- Migraine114
- Pain Management113
- Amyotrophic Lateral Sclerosis108
Leading sponsors
- Beijing Tiantan Hospital133
- Riphah International University125
- Assistance Publique - Hôpitaux de Paris112
- Mayo Clinic98
- Xuanwu Hospital, Beijing93
- VA Office of Research and Development92
- Hospices Civils de Lyon79
- Johns Hopkins University70
- National Taiwan University Hospital70
- University of Minnesota64
Where studies are running
- California680
- Massachusetts299
- New York292
- Florida274
- Texas267
- Maryland246
- Arizona213
- Alabama209
- Illinois189
- Pennsylvania177
Recruiting studies12,405 total
- NCT05294029Recruiting
Study of movement and aging in adults with neuromotor disability
This study looks at how neuro-related movement problems change as people age. It may help improve care plans for adults with neuromotor disabilities by learning what happens over time.
GarchesAges 18 years+ - NCT04829708RecruitingPhase 3
Preventing brain spread in limited-stage small cell lung cancer
This trial compares two ways to manage limited-stage small cell lung cancer that has improved after initial chemotherapy and radiation. Participants will either get preventive brain radiation or have regular brain MRI scans instead, to see which approach is safer and works better.
Jinan, ShandongAges 18–75 - NCT04929236RecruitingPhase 3
Testing different PANZYGA doses for children with CIDP
This Phase 3 study compares different dose schedules of PANZYGA (immune-globulin) in children with chronic inflammatory demyelinating polyradiculoneuropathy (CIDP). It aims to find a dosing plan that is both safe and effective for improving symptoms and function.
Birmingham, AlabamaAges 2–17 - NCT04686877Recruiting
Surgery to remove deep brain bleeding with urokinase
This trial tests whether a targeted (stereotactic) procedure to remove deep brain bleeding, combined with a medicine called urokinase, is safer and works better than standard care. It focuses on people whose bleeding is in the deep brain and who are able to undergo surgery within a specific time window.
Fuzhou, FujianAges 40 years+ - NCT04648124Recruiting
MRI brain scan study in hereditary retinal vision loss
This study uses functional MRI (a type of brain scan) to understand how the brain processes vision in people with inherited retinal disorders. You might be included if you are an adult with hereditary retinal degeneration and are planning certain vision-related treatments soon.
Paris, PARISAges 18 years+ - NCT05124132Enrolling by invitation
Study of resilience and brain health after an earlier parent study
This trial looks at how resilience (how well people cope with stress) and brain health change over time in older adults who already joined an earlier study. You may be eligible if you participated in that “parent study.”
St Louis, MissouriAges 65 years+ - NCT04889794Recruiting
Helps pharmacists support seniors with memory problems after work changes
This study looks at whether reorganizing work in family medicine clinics changes how pharmacists review and support seniors who have major memory (cognitive) problems. It may help improve medication support and seniors’ autonomy with guidance that fits their needs.
Montreal, QuebecAges 65 years+ - NCT04874220Recruiting
Brain study of real-world navigation in people with RNS
This study looks at how the brain works while people navigate in everyday life. It includes people who already have an RNS device placed in their brain and helps researchers understand the brain activity tied to spatial navigation.
Los Angeles, CaliforniaAges 12–70 - NCT05079516Recruiting
Study how the brain learns using arm testing and brain stimulation
This study uses a reaching task and a brain stimulation method (TMS) to see which brain areas help sensory learning. It may help researchers understand how learning works in the brain and how to design better therapies, if needed.
Bloomington, IndianaAges 18–45 - NCT05036564Recruiting
Biopsy and spinal fluid testing for newly diagnosed brain lymphoma
This study uses brain biopsy and spinal fluid (lumbar puncture) tests to better diagnose and understand how well treatments may work for certain lymphomas in the brain. It may help doctors match the right therapy by studying what the disease looks like in the body and brain.
Milan, Italy/LombardyAges 18 years+ - NCT05457569Recruiting
Parent support program for babies at high brain risk
This study checks whether a coordinated parent support program delivered after NICU (and after discharge) is practical and helpful. It gathers feedback through interviews with parents and professionals to improve how care and parenting support are organized.
DijonAges 18 years+ - NCT04316039RecruitingPhase 2/Phase 3
Radiation alone or with temozolomide for brain tumor after surgery
This trial compares standard radiation therapy versus radiation plus a chemotherapy medicine called temozolomide in people with a newly diagnosed low-grade (WHO grade II) brain glioma after surgery. It’s designed to see if adding temozolomide improves outcomes while managing side effects.
Chengdu, SichuanAges 18–70 - NCT05600764Recruiting
Study of how TRPV4 nerve disease develops over time
This study looks at the natural history of TRPV4-related neuropathy—how it starts and changes over time. It may help doctors better understand the condition, especially for people with TRPV4 gene changes.
Baltimore, MarylandAges 3–80 - NCT04313140Recruiting
MRI virtual biopsy to predict glioma grade
This study uses special MRI images to estimate the “grade” of a suspected brain tumor (glioma) without taking a tissue sample first. If it works well, it may help doctors better plan care based on imaging.
PoitiersAges 18 years+ - NCT04261127Recruiting
Testing a genetic tool to diagnose recessive ataxia
This study checks how well a computer algorithm (called RADIAL) can find the cause of autosomal recessive cerebellar ataxia using genetic information. It may help confirm diagnoses when the genetic cause is still unknown and other causes have already been ruled out.
BesançonAges 5 years+ - NCT03948971Recruiting
Measuring normal brain vein pressure during angiograms
This study measures pressure in the brain’s draining veins during a planned (elective) brain angiogram. It may help doctors better understand “normal” vein pressure, especially for people being evaluated for other conditions.
Winston-Salem, North CarolinaAges 18–60 - NCT04070040RecruitingPhase 2
Camrelizumab for returning brain lymphoma after prior treatment
This trial studies camrelizumab (an immune medicine) for primary CNS lymphoma that has come back after standard treatment. It aims to shrink the lymphoma seen on MRI and help control the disease with a new immune-based approach.
BeijingAges 18 years+ - NCT05527067Recruiting
Study of alpha-synuclein brain disease in patients and healthy people
This study follows people with a primary alpha-synuclein diagnosis and compares them with healthy controls. It aims to better understand this condition and may help researchers design better future tests and treatments.
Fuzhou, FujianAges 30–80 - NCT05466383Recruiting
Screening and treatment support for adolescent spinal curve in China
This study checks adolescents who have an AIS spinal curve and then offers an intervention. It may help by testing what screening and treatment approach works best for improving or managing the curve.
Haikou, HainanAges 9–16 - NCT05273970Enrolling by invitation
Brain recording study during electrode surgery for drug-resistant epilepsy
This study uses special brain recordings done during electrode implantation to better understand brain activity in people whose symptoms are hard to control with medications. The goal is to help doctors improve how they evaluate and treat certain brain or nerve conditions.
Phoenix, ArizonaAges 18–80 - NCT04381663Enrolling by invitation
Tracking symptoms in degenerative neck spine narrowing
This study follows adults with degenerative narrowing in the neck spine to see how symptoms and function change over time. It may help doctors better understand which patients improve or worsen, and why.
BaselAges 18 years+ - NCT05558371Recruiting
International study for people with CDKL5 disorder
This study is for anyone diagnosed with CDKL5 disorder who can be seen at participating clinics or is already listed in an international CDKL5 registry. The goal is to help researchers better understand the condition and support future research.
Los Angeles, CaliforniaAges 1 month–100 years - NCT05589831Recruiting
Test breathing support and brain health in premature babies
This study checks how a type of breathing machine support affects brain health in very premature infants. It may help doctors choose safer breathing support strategies to protect the brain.
Toronto, OntarioAges 3 days+ - NCT03571334RecruitingPhase 2
Botox injections for nerve pain after chemotherapy in breast cancer
This trial studies whether botulinum toxin A (Botox) injections can reduce nerve pain caused by chemotherapy in people with breast cancer. It may help if your pain started soon after chemotherapy and fits the trial’s specific nerve-pain pattern.
Milwaukee, WisconsinAges 18 years+
Common questions
- How many brain & nervous system clinical trials are recruiting?
- Clin2 is tracking 12,407 recruiting neurology studies from the U.S. registry right now, out of 19,276 we cover in this area in total.
- What does “Brain & nervous system” cover here?
- Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We group each study into brain & nervous system based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a brain & nervous system trial near me?
- Use the search to filter brain & nervous system studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.