Neurology
Brain & nervous system clinical trials
Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We’re tracking 12,407 recruiting studies in this area right now.
By phase
- Not applicable9,742
- Phase 2782
- Phase 1577
- Phase 3534
- Phase 4342
- Phase 1/Phase 2307
- Phase 2/Phase 3123
Top conditions
- Stroke843
- Parkinson Disease429
- Alzheimer Disease342
- Multiple Sclerosis342
- Dementia226
- Ischemic Stroke200
- Epilepsy197
- Obstructive Sleep Apnea156
- Spinal Cord Injuries153
- Insomnia152
- Sarcopenia150
- Traumatic Brain Injury150
- Acute Ischemic Stroke138
- Cerebral Palsy131
- Mild Cognitive Impairment129
- Migraine114
- Pain Management113
- Amyotrophic Lateral Sclerosis108
Leading sponsors
- Beijing Tiantan Hospital133
- Riphah International University125
- Assistance Publique - Hôpitaux de Paris112
- Mayo Clinic98
- Xuanwu Hospital, Beijing93
- VA Office of Research and Development92
- Hospices Civils de Lyon79
- Johns Hopkins University70
- National Taiwan University Hospital70
- University of Minnesota64
Where studies are running
- California680
- Massachusetts299
- New York292
- Florida274
- Texas267
- Maryland246
- Arizona213
- Alabama209
- Illinois189
- Pennsylvania177
Recruiting studies12,405 total
- NCT02701036Recruiting
Natural history study for adult-onset progressive ataxia
This study follows people with progressive balance and coordination problems that started after age 40. The goal is to better understand what happens over time, which can help future treatments be developed for similar conditions.
InnsbruckAges 40 years+ - NCT06743607Recruiting
Spinal stimulation to improve arm and hand function at home
This trial tests whether using a special device that sends small electrical currents to the spinal cord can help people recovering from a recent spinal cord injury regain movement in their arms and hands. The treatment happens in your home with the help of a caregiver.
Englewood, ColoradoAges 18 years+ - NCT07597603Recruiting
Unconscious Mind Training Study
This study tests a training program designed to work with your unconscious mind. Researchers want to see if this approach can help you in ways you might not immediately notice.
Naples, FloridaAges 10–75 - NCT06747728Recruiting
Bevacizumab before surgery for new high-grade brain tumors
This trial tests whether giving bevacizumab (a drug that blocks blood vessel growth) before surgery helps treat newly diagnosed high-grade gliomas. It may be an option for adults who have not had prior anti-angiogenic therapy.
Zhengzhou, HenanAges 18 years+ - NCT06738030Recruiting
Brain stimulation and listening training for hearing in noise
This study tests whether a gentle brain stimulation technique (transcranial stimulation) combined with listening exercises can help people who have trouble hearing speech in noise. If you are 50 or older and struggle to follow conversations in crowded places, this trial may be a good fit.
Boston, MassachusettsAges 50 years+ - NCT06736171Recruiting
Walking recovery after stroke using a robotic exoskeleton
This study tests if a robotic exoskeleton can help people who have had a stroke walk again. You must be between 3 and 8 months post-stroke, able to walk with a cane or walker, and fit certain physical requirements.
West Orange, New JerseyAges 50–80 - NCT07330921Recruiting
Testing a new 3D seating system for kids with motor issues
This trial is testing a new 3D seating system designed for children with motor control problems. It aims to see if this system helps them sit better and be more comfortable.
Zaragoza, ZaragozaAges 2–6 - NCT07496255Recruiting
Virtual reality for memory help after ICU confusion
This trial tests whether using virtual reality (VR) can help older adults recover their thinking and memory after a serious illness and confusion in the ICU. You may be eligible if you are 50 or older, spent time on a breathing machine, and had delirium in the ICU.
Indianapolis, IndianaAges 50 years+ - NCT06444412RecruitingPhase 2
Testing a new PET scan to detect brain tumor recurrence
This trial tests a special imaging scan called Ga-68 PSMA-11 PET/CT to see if it can better detect when a glioma brain tumor has come back or progressed. It is for people who have already had standard treatment and are planning surgery for a suspected recurrence.
Rochester, MinnesotaAges 18 years+ - NCT06401057Recruiting
Long-term brain function tracking for brain lesions
This study creates a registry to track brain function over time in people with brain lesions. It aims to better understand how the brain works and may help improve future care.
HeidelbergAges 18 years+ - NCT06201429Recruiting
New device for draining fluid after brain surgery
This study tests a new device to remove extra fluid from the brain during surgery. It may be an option if you need a brain operation that uses a drain.
Buffalo, New YorkAges 22–65 - NCT06083220Recruiting
School readiness in preschool children with cerebral palsy
This study looks at how ready preschool-aged children with cerebral palsy (affecting one side of the body) are for school. It will help understand what skills they may need extra support with.
Frisco, TexasAges 3 years–5.9 years - NCT06269939Recruiting
Memory training for healthy aging and mild memory loss
This study tests a special memory training program for people with mild memory problems (MCI) or healthy aging. It aims to improve how you learn and remember new information using guided methods.
East Hanover, New JerseyAges 60 years+ - NCT07291128Recruiting
VOJTA therapy for children with ataxic cerebral palsy
This trial tests a special movement therapy called VOJTA technique to help improve balance and coordination in children with ataxic cerebral palsy. It may offer a gentle way to help your child move better.
Lahore, Punjab ProvinceAges 2–6 - NCT03660917RecruitingPhase 2/Phase 3
Riluzole treatment for SCA7 nerve balance problems
This trial studies whether riluzole can help people with spinocerebellar ataxia type 7 (SCA7), a genetic condition that affects balance and coordination. It may help slow symptoms or improve daily function, and you’d be closely monitored for side effects.
RomeAges 7 years+ - NCT06261424Recruiting
Exercise program for spastic ataxia types ARSACS and SPG7
This study tests whether a supervised exercise program (including pool exercises) can help people with certain types of hereditary ataxia. The goal is to see if it reduces symptoms like muscle stiffness and coordination problems.
Baie-Saint-Paul, QuebecAges 16 years+ - NCT01912313Recruiting
Testing nerve signals in gut samples from IBS patients
This study looks at how nerves behave in small gut tissue samples (biopsies) from people with irritable bowel syndrome (IBS) and healthy volunteers. The goal is to better understand IBS symptoms and what might be driving them.
Leuven, Vlaams-BrabantAges 18–99 - NCT06315231RecruitingPhase 2
Stroke Recovery Thinking Trial for Recent Stroke Patients
This study tests an under-the-tongue tablet (edaravone dexborneol) to help thinking and memory problems that can happen after an ischemic stroke. It may help people who recently had a stroke and now have trouble with attention, memory, or planning.
Fuyang, AnhuiAges 40–80 - NCT07284342Recruiting
Study on sleep and advanced Parkinson's with foslevodopa/foscarbidopa
This study looks at how a Parkinson's drug delivered under the skin (foslevodopa/foscarbidopa) affects sleep problems in people with advanced Parkinson's. It is a real-world study that follows your usual treatment, no new experimental drug is being tested.
Málaga, AndalusiaAges 18 years+ - NCT06287736Recruiting
Spinal cord stimulation for diabetic nerve pain
This study tests whether a spinal cord stimulator (a device that uses mild electrical pulses to block pain signals) can help people with diabetic nerve pain that hasn't responded to other treatments. If you have long-term nerve pain from diabetes and other pain meds haven't worked, this trial might be an option for you.
Columbus, OhioAges 18 years+ - NCT06876688RecruitingPhase 2
Relma-cel and Tislelizumab for CNS Lymphoma
This trial tests a combination of two drugs for people with large B-cell lymphoma that has spread to the brain or spinal cord and has come back or not responded well to earlier treatments. The first drug, Relma-cel, is a type of immunotherapy that helps your immune system attack cancer cells. The second drug, Tislelizumab, helps keep your immune system active against the cancer.
BeijingAges 18 years+ - NCT05138588Recruiting
rTMS for thinking ups and downs in Lewy body dementia
This study tests whether repeat rTMS sessions can improve thinking “fluctuations” (noticeable ups and downs) in people with Lewy body dementia. It’s a proof-of-concept trial, meaning it’s mainly to see if the approach is feasible and potentially helpful.
StrasbourgAges 45 years+ - NCT03761121Recruiting
Imaging study for low-grade glioma in children and adults
This study is testing how to take faster, better brain images in people diagnosed with low-grade glioma (a type of brain tumor). Better imaging may help doctors see the tumor more clearly while reducing time spent in the scanner.
Boston, MassachusettsAges birth+ - NCT07271485RecruitingEarly Phase 1
Propranolol for misophonia: a pilot study
This trial tests if a blood pressure medication called propranolol can reduce the intense anger or anxiety some people feel in response to everyday sounds (like chewing or breathing). If you have misophonia and meet the study’s health and safety criteria, you may be able to join and receive the medication under medical supervision at a clinic in Littleton, Colorado.
Littleton, ColoradoAges 18–65
Common questions
- How many brain & nervous system clinical trials are recruiting?
- Clin2 is tracking 12,407 recruiting neurology studies from the U.S. registry right now, out of 19,276 we cover in this area in total.
- What does “Brain & nervous system” cover here?
- Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We group each study into brain & nervous system based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a brain & nervous system trial near me?
- Use the search to filter brain & nervous system studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.