Neurology
Brain & nervous system clinical trials
Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We’re tracking 12,407 recruiting studies in this area right now.
By phase
- Not applicable9,742
- Phase 2782
- Phase 1577
- Phase 3534
- Phase 4342
- Phase 1/Phase 2307
- Phase 2/Phase 3123
Top conditions
- Stroke843
- Parkinson Disease429
- Alzheimer Disease342
- Multiple Sclerosis342
- Dementia226
- Ischemic Stroke200
- Epilepsy197
- Obstructive Sleep Apnea156
- Spinal Cord Injuries153
- Insomnia152
- Sarcopenia150
- Traumatic Brain Injury150
- Acute Ischemic Stroke138
- Cerebral Palsy131
- Mild Cognitive Impairment129
- Migraine114
- Pain Management113
- Amyotrophic Lateral Sclerosis108
Leading sponsors
- Beijing Tiantan Hospital133
- Riphah International University125
- Assistance Publique - Hôpitaux de Paris112
- Mayo Clinic98
- Xuanwu Hospital, Beijing93
- VA Office of Research and Development92
- Hospices Civils de Lyon79
- Johns Hopkins University70
- National Taiwan University Hospital70
- University of Minnesota64
Where studies are running
- California680
- Massachusetts299
- New York292
- Florida274
- Texas267
- Maryland246
- Arizona213
- Alabama209
- Illinois189
- Pennsylvania177
Recruiting studies12,405 total
- NCT06345625Recruiting
Balance and walking with head movement in older adults
This study looks at how older adults keep their balance and walk when their head is moving. You may be asked to stand or walk while your head gently moves, so researchers can understand how your body reacts.
AntwerpAges 65–100 - NCT05711394RecruitingPhase 3
Atogepant for preventing episodic migraine in children
This study tests whether an oral medicine called atogepant can reduce migraine activity in children ages 6–17 and checks its side effects. It’s meant for kids with episodic migraine (not the more constant types) who may benefit from preventive treatment.
Huntsville, AlabamaAges 6–17 - NCT06902298RecruitingPhase 1/Phase 2
Ultrasound brain stimulation for depression
This trial tests a new, non-invasive ultrasound treatment for people with depression who haven't gotten enough relief from at least two prior treatments. It uses sound waves to gently stimulate areas of the brain linked to mood.
Salt Lake City, UtahAges 18–65 - NCT04866251Recruiting
Tests gag reflex differences in healthy people and patient groups
This study measures your gag reflex (how strongly you gag when stimulated) and compares it across different groups. The results may help improve screening for swallowing problems (called dysphagia).
Giessen, HesseAges 18 years+ - NCT07699562Recruiting
EMG device study in healthy people and ICU patients
This study tests a device that records muscle activity (EMG) in healthy volunteers and critically ill patients in the ICU. It aims to learn how well the device works in different groups, which could help monitor muscle function in the future.
Evanston, IllinoisAges 18–90 - NCT04906096RecruitingPhase 2
Paxalisib for repeat or resistant brain lymphoma
This Phase 2 study tests paxalisib to shrink or control primary CNS lymphoma that has come back or did not respond to prior treatment. It may help by blocking specific cell-growth signals that can drive this lymphoma.
Boston, MassachusettsAges 18 years+ - NCT06323057Recruiting
TMS and reward learning in healthy adults
This study uses a painless magnetic stimulation technique called TMS to see how it affects the way the brain learns from rewards. It's for healthy adults who want to help scientists understand basic brain function.
Newark, New JerseyAges 18–55 - NCT07136441Recruiting
Sciatic nerve stiffness test for leg pain patients
This study measures how stiff the sciatic nerve is using ultrasound while you do gentle leg movements. It compares people with sciatica to healthy volunteers to understand nerve changes.
GizaAges 25–40 - NCT03639285Recruiting
Study of inherited leukodystrophy symptoms and outcomes
This study follows people with inherited leukodystrophies to better understand how the condition is diagnosed and how it changes over time. It may help doctors improve testing and care planning by collecting clinical and imaging information.
Salt Lake City, UtahAges Any age - NCT06860633RecruitingPhase 4
Efgartigimod for worsening myasthenia gravis in hospital
This trial tests a drug called efgartigimod for people with myasthenia gravis who are in the hospital because their symptoms are getting worse. The goal is to see if it can help them recover faster and avoid needing a breathing tube.
Aurora, ColoradoAges 18 years+ - NCT03154697Recruiting
Study for parents of children with Smith-Magenis syndrome and sleep issues
This study builds a database about people with Smith-Magenis syndrome and their sleep problems. It wants information from the child’s parent or legal guardian to better understand sleep disturbances.
Washington D.C., District of ColumbiaAges 3–65 - NCT07639359RecruitingPhase 2
Ketamine for depression in intensive care patients
This study tests whether low-dose ketamine infusions can reduce depressive symptoms in patients staying in the intensive care unit for at least 6 days. Ketamine is a medication that may work differently than standard antidepressants and could provide faster relief.
Jacksonville, FloridaAges 18–99 - NCT06449495Recruiting
Virtual reality therapy for balance and coordination in kids
This trial tests whether a virtual reality (VR) program can help children with balance or coordination problems improve their movement skills. It's for kids ages 4 to 17 who can walk and follow simple instructions.
Bosisio Parini, LeccoAges 4–17 - NCT03458676Recruiting
MRI results to help guide brain tumor biopsy
This study checks whether advanced brain MRI images can help doctors choose the best spot to biopsy suspected or proven primary brain tumors. It may help make biopsies safer and more accurate before tissue diagnosis.
Houston, TexasAges 18 years+ - NCT02995538Recruiting
Registry for people with suspected genetic nerve disorders
This registry collects health and family history from people who may have an inherited (genetic) neurological condition. It helps researchers understand what genetic causes are involved and may lead to better future care.
Pittsburgh, PennsylvaniaAges Any age - NCT06822920Recruiting
Collagen Patch for Repairing Brain or Spinal Covering
This study is testing a special collagen patch (called Dura Membranes) used by surgeons to repair tears in the outer covering of the brain or spinal cord. If you need this type of repair and don't have a cow collagen allergy, you may be able to join.
Milwaukee, WisconsinAges 18 years+ - NCT07651540Recruiting
Understanding Sensory Nerve Damage: The Neuronoscore Study
This study helps doctors better understand and measure sensory nerve damage (nerves that feel pain, temperature, and touch). You may qualify if you have a specific type of nerve damage caused by cancer, autoimmune disease, platinum chemotherapy, or a rare genetic condition.
AngersAges 18 years+ - NCT07148466Recruiting
Shoulder and arm exercises for stroke with shoulder blade issues
This trial tests if specific shoulder and arm exercises can improve movement and walking in people who had a stroke and have shoulder blade problems. It may help if you have some muscle tightness but can still follow instructions.
Islamabad, Punjab ProvinceAges 40–65 - NCT07629674Recruiting
Video Therapy to Help Leg Movement Recovery After Stroke
This study tests whether watching specially designed videos can help improve leg strength and walking ability in people recovering from stroke. You'll receive this video therapy alongside your regular rehabilitation care.
Saint-EtienneAges 18–80 - NCT06221722Recruiting
Brain scan study for treating constipation
This trial uses brain scans to see if doctors can predict how well constipation treatments will work. It is for adults with functional constipation, but only if they have no other digestive problems or medical implants.
Yinchuan, NingxiaAges 18–45 - NCT06430814Recruiting
Blood test to predict nerve damage from paclitaxel
This study looks at whether certain markers in your blood can predict nerve damage from paclitaxel chemotherapy. If you join, researchers will monitor your nerve health during treatment to better understand and possibly prevent side effects.
OdenseAges 18 years+ - NCT07419633Recruiting
Study on supplements to improve strength and thinking in older adults
This trial tests if two supplements, HMB and 2-HOBA, taken alone or together, can help improve muscle strength and mental function in healthy adults over 65. The goal is to see if these supplements can improve overall quality of life.
Montreal, QuebecAges 65 years+ - NCT06339268Recruiting
Brain and body training to prevent confusion after lung surgery
This study tests whether special physical and brain exercises before and after lung surgery can help older adults (ages 60+) avoid confusion or memory problems. Participants will use a tablet or phone to follow the program.
BelgradeAges 60 years+ - NCT06746909Recruiting
Brain inflammation and imaging in older adults at risk for dementia
This study looks at how changes in the brain (like inflammation) relate to thinking and memory decline in older adults. It uses brain scans and computer tools to find early signs of dementia risk, with the goal of better preventing memory loss.
PisaAges 65–89
Common questions
- How many brain & nervous system clinical trials are recruiting?
- Clin2 is tracking 12,407 recruiting neurology studies from the U.S. registry right now, out of 19,276 we cover in this area in total.
- What does “Brain & nervous system” cover here?
- Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We group each study into brain & nervous system based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a brain & nervous system trial near me?
- Use the search to filter brain & nervous system studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.