Neurology
Brain & nervous system clinical trials
Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We’re tracking 11,939 recruiting studies in this area right now.
By phase
- Not applicable9,342
- Phase 2765
- Phase 1556
- Phase 3513
- Phase 4339
- Phase 1/Phase 2299
- Phase 2/Phase 3125
Top conditions
- Stroke796
- Parkinson Disease394
- Alzheimer Disease338
- Multiple Sclerosis330
- Dementia225
- Epilepsy192
- Ischemic Stroke190
- Insomnia159
- Traumatic Brain Injury151
- Obstructive Sleep Apnea142
- Spinal Cord Injuries142
- Acute Ischemic Stroke139
- Sarcopenia135
- Mild Cognitive Impairment126
- Cerebral Palsy119
- Pain Management113
- Migraine107
- Fibromyalgia105
Leading sponsors
- Beijing Tiantan Hospital124
- Assistance Publique - Hôpitaux de Paris109
- Riphah International University105
- Mayo Clinic98
- VA Office of Research and Development92
- Xuanwu Hospital, Beijing89
- Hospices Civils de Lyon77
- Johns Hopkins University69
- University of Minnesota63
- Washington University School of Medicine63
Where studies are running
- California658
- Massachusetts304
- New York295
- Florida267
- Texas266
- Maryland248
- Arizona208
- Alabama207
- Illinois183
- Pennsylvania176
Recruiting studies11,939 total
- NCT07774598Recruiting
Non-invasive nerve stimulation for essential tremor
This trial is testing whether a device that gently stimulates the nerves in your arm (called non-invasive neuromodulation) can safely reduce hand tremors over a long period. It might help with activities like eating, writing, or dressing.
ShanghaiAges 18–75 - NCT07769814Recruiting
Better CT imaging for brain stent checkups
This study looks at whether a new type of CT scanner can take clearer pictures of stents in the brain. The goal is to help doctors see if the stent is working well after it's been placed.
Beijing, Beijing MunicipalityAges 5–90 - NCT07767981Recruiting
Gut bacteria and side effects of precise radiation therapy
This study looks at how the bacteria in your gut might affect side effects from a precise type of radiation therapy called stereotactic radiosurgery. By collecting samples, researchers hope to find ways to reduce side effects in the future.
Chicago, IllinoisAges 18 years+ - NCT07775625Recruiting
Music therapy for anxiety in Alzheimer's disease
This study tests whether a specially designed music activity can help lower anxiety in people with Alzheimer's disease. If you or a loved one has Alzheimer's and feels anxious, this trial may offer a non-drug way to feel calmer.
Chicago, IllinoisAges 55 years+ - NCT06566066Recruiting
Thyroid hormone resistance patient registry
This study creates a registry for people with thyroid hormone resistance caused by specific genetic mutations. It helps doctors collect data to better understand and treat the condition.
BerlinAges Any age - NCT06567197Recruiting
MS treatment with stem cell transplant in the Netherlands
This trial studies a stem cell transplant treatment for relapsing-remitting multiple sclerosis (RRMS). It aims to see how well this therapy works for people in the Netherlands who have already been approved for it.
AmsterdamAges 18–65 - NCT06567431Recruiting
Blood and tears in alzheimer's disease
This study looks at different fluids from the body, like blood and tears, to find better ways to diagnose and track alzheimer's and related dementias. It compares people with these conditions to healthy volunteers to see what biological markers differ.
CopenhagenAges 30 years+ - NCT04460521RecruitingPhase 4
NAC pills and night splints for carpal tunnel without surgery
This trial tests whether N-acetylcysteine (NAC) along with wearing a night wrist splint can improve symptoms of mild to moderate carpal tunnel syndrome. It’s designed for people who want a non-surgical option.
Halifax, Nova ScotiaAges 18 years+ - NCT06567795Recruiting
Monitoring heart risk with a wearable sensor in diabetes
This trial tests a wearable chest sensor (called HEMOTAG) to monitor heart events in people with long-standing Type 2 diabetes who also have heart disease or specific diabetes-related complications. The sensor is worn at home for short periods to catch early signs of heart trouble, aiming to improve personalized care.
West Palm Beach, FloridaAges 40 years+ - NCT06449547Recruiting
Risk factors for anxiety and depression in shingles nerve pain
This study looks at what makes people with shingles nerve pain more likely to feel anxious or depressed. By joining, you'll help doctors understand how to better support patients like you.
Wuhan, HubeiAges 18 years+ - NCT06571929Recruiting
Augmented reality training for arm function in children with cerebral palsy
This study tests whether playing special augmented reality games (where virtual objects appear in the real world) can improve arm and hand function in children with spastic cerebral palsy. It compares game training to usual therapy.
São Carlos, São PauloAges 6–12 - NCT06569472RecruitingPhase 1
CAR-T cell therapy for tough juvenile dermatomyositis
This trial tests a treatment using your own immune cells, modified to target a protein called CD19, for children and teens with juvenile dermatomyositis that hasn't gotten better with standard treatments. The goal is to see if this therapy can help calm the inflammation and improve symptoms.
Hangzhou, ZhejiangAges 5–17 - NCT06570421Recruiting
Nerve stimulation for Parkinson's and essential tremor
This study tests a non-invasive nerve stimulation device for reducing tremors in people with Parkinson's disease or essential tremor. It follows up participants from a previous trial to see if benefits last up to 24 months.
OstravaAges 18 years+ - NCT03336008Recruiting
Registry for certain inherited spinocerebellar ataxias
This study is a registry that collects information from adults with certain types of inherited ataxia caused by specific genetic diagnoses. It may help doctors better understand these conditions and support future research.
Hong Kong, ShatinAges 18–90 - NCT06572475Recruiting
New MRI contrast for brain tumors
This trial uses a new type of MRI contrast dye (USPIO) to get clearer images of certain slow-growing brain tumors (vestibular schwannomas and low-grade gliomas). The goal is to see if this dye helps doctors better understand and treat these tumors.
Salford, Greater ManchesterAges 16–100 - NCT06501391RecruitingPhase 2
Brain radiation plus chemo-immunotherapy for untreated NSCLC with stable brain metastases
This trial tests whether combining brain radiation with chemotherapy and immunotherapy can help people with advanced lung cancer that has spread to the brain but has not yet been treated. It is for those whose tumors do not have certain gene mutations (EGFR, ALK, ROS1).
ShanghaiAges 18 years+ - NCT07758920RecruitingPhase 2
New tablet for long-term shingles pain
This trial tests a new tablet called HL-1186 for treating post-herpetic neuralgia (long-lasting pain after shingles). It compares the new drug to pregabalin, a standard treatment, to see if it's safer and more effective.
BeijingAges 18 years+ - NCT07762118Recruiting
Brain stimulation with language learning for adults
This study tests whether combining a gentle brain stimulation technique with structured language-learning sessions can help adults improve their language skills. It might be an option if you are interested in boosting your language learning.
Boston, MassachusettsAges 18 years+ - NCT07758595RecruitingPhase 1
Study of DNL921 for healthy people and people with Alzheimer's disease
This trial tests an investigational drug called DNL921 in healthy volunteers and in people with mild to moderate Alzheimer's disease. The goal is to see if it is safe and how the body handles it, which is a first step in finding a new treatment.
ManchesterAges 18–75 - NCT07762092Recruiting
Registry of lecanemab treatment for Alzheimer's in Canada
This study collects information from people in Canada who have Alzheimer's disease and are prescribed the drug lecanemab (LEQEMBI). It helps doctors learn more about the drug's safety and effects in real-world use.
Calgary, AlbertaAges Any age - NCT07762365Recruiting
Brain stimulation with reading help for children with dyslexia
This study tests whether pairing a gentle brain stimulation technique with structured reading instruction can improve reading skills in children with dyslexia. It aims to find a new way to support reading development.
Boston, MassachusettsAges 7–17 - NCT07765446RecruitingPhase 2
Study of SIR2501 for nerve pain during chemotherapy
This trial tests whether SIR2501 can prevent or reduce nerve pain caused by paclitaxel chemotherapy. It is for people with solid tumors who are about to start paclitaxel treatment.
Hollywood, FloridaAges 18 years+ - NCT07764146RecruitingPhase 1
Study of VY1706 for early Alzheimer's disease
This study tests an experimental treatment called VY1706 for people with early Alzheimer's disease. It aims to see if the treatment is safe and how well it works, and may help slow down the disease.
Maitland, FloridaAges 30–80 - NCT06265103Recruiting
Epilepsy learning healthcare system registry
This is a registry study that collects information from people being treated for epilepsy at participating healthcare centers. The goal is to improve care by learning from real-world patient data.
Phoenix, ArizonaAges Any age
Common questions
- How many brain & nervous system clinical trials are recruiting?
- Clin2 is tracking 11,939 recruiting neurology studies from the U.S. registry right now, out of 18,371 we cover in this area in total.
- What does “Brain & nervous system” cover here?
- Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We group each study into brain & nervous system based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a brain & nervous system trial near me?
- Use the search to filter brain & nervous system studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.