Neurology
Brain & nervous system clinical trials
Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We’re tracking 12,407 recruiting studies in this area right now.
By phase
- Not applicable9,742
- Phase 2782
- Phase 1577
- Phase 3534
- Phase 4342
- Phase 1/Phase 2307
- Phase 2/Phase 3123
Top conditions
- Stroke843
- Parkinson Disease429
- Alzheimer Disease342
- Multiple Sclerosis342
- Dementia226
- Ischemic Stroke200
- Epilepsy197
- Obstructive Sleep Apnea156
- Spinal Cord Injuries153
- Insomnia152
- Sarcopenia150
- Traumatic Brain Injury150
- Acute Ischemic Stroke138
- Cerebral Palsy131
- Mild Cognitive Impairment129
- Migraine114
- Pain Management113
- Amyotrophic Lateral Sclerosis108
Leading sponsors
- Beijing Tiantan Hospital133
- Riphah International University125
- Assistance Publique - Hôpitaux de Paris112
- Mayo Clinic98
- Xuanwu Hospital, Beijing93
- VA Office of Research and Development92
- Hospices Civils de Lyon79
- Johns Hopkins University70
- National Taiwan University Hospital70
- University of Minnesota64
Where studies are running
- California680
- Massachusetts299
- New York292
- Florida274
- Texas267
- Maryland246
- Arizona213
- Alabama209
- Illinois189
- Pennsylvania177
Recruiting studies12,405 total
- NCT06637579Recruiting
Exercise Program for Walking in Children with Cerebral Palsy
This trial tests a special exercise program (Universal Exercise Unit) plus task-focused training for children with spastic cerebral palsy. It aims to help with walking, balance, and daily activities.
Sialkot, Punjab ProvinceAges 5–15 - NCT06746415Recruiting
Robot-assisted walking training for chronic stroke
This study tests whether robot-assisted walking training helps people who had a stroke at least 6 months ago. It aims to improve walking ability and leg movement for those still having some walking difficulty.
Istanbul, ZeytinburnuAges 40–75 - NCT07576179Recruiting
Foot Muscle Exercises for Diabetic Nerve Damage
This study tests whether special exercises that strengthen the small muscles in your foot and ankle can help improve balance, reduce fall risk, and ease walking difficulties caused by diabetic nerve damage (diabetic peripheral neuropathy). You'll be compared to a group doing different ankle and foot exercises.
Sargodha, Punjab ProvinceAges 50–75 - NCT07142304Recruiting
A study of compression gloves and boots to prevent chemo nerve damage
This trial is testing a wearable device (gloves and boots) that applies gentle compression to your hands and feet during chemotherapy. It aims to prevent or reduce nerve damage (numbness, tingling, pain) that some chemotherapy drugs can cause.
Poway, CaliforniaAges 18 years+ - NCT06747637Recruiting
Spanish-language program for Latino dementia caregivers
This study tests a program designed to support Latino and Hispanic caregivers of people with dementia. It is delivered in Spanish and aims to see if it helps caregivers manage their role and well-being.
Los Angeles, CaliforniaAges 18–100 - NCT07139002Recruiting
Sensory training with Bobath therapy for chronic stroke
This study tests whether combining sensory training with Bobath therapy (a type of physical therapy) helps people with chronic stroke improve their balance and movement. If you've had a stroke between 6 months and 2 years ago and struggle with balance, this trial may offer a way to enhance your recovery.
Lahore, Punjab ProvinceAges 45–60 - NCT06421077Recruiting
Ear nerve stimulation to prevent confusion after surgery in older adults
This trial tests if a gentle electrical stimulation on the ear can help prevent postoperative delirium (sudden confusion) in older patients after surgery. It focuses on people 65 and older who will have longer operations.
BeijingAges 65 years+ - NCT06776458Recruiting
Aromatase inhibitor effects on heart and brain health in breast cancer
This study looks at how aromatase inhibitors (a type of hormone therapy for breast cancer) affect your heart and brain health over time. It compares women with breast cancer who have taken these drugs to healthy women of similar age.
Toronto, OntarioAges Any age - NCT07570680Recruiting
Brain Bleeding Stroke AI Decision Support System
This study tests an artificial intelligence system designed to help doctors make better treatment decisions for patients with sudden brain bleeding. The AI analyzes CT scans and patient information to guide care choices during hospitalization.
NanchangAges 8 years+ - NCT05375812Recruiting
Deep health study of Gulf War veteran symptoms and brain-body changes
This study closely measures health, thinking, and body function in Gulf War veterans using detailed testing (including exercise testing and possibly brain scans). It aims to better understand what may be driving Gulf War illness and related symptoms, which could improve future care.
Bethesda, MarylandAges 48–70 - NCT06624202Recruiting
Football study testing mouthpiece to reduce concussions
This trial tests a new mouthpiece that tracks head impacts during football practice and games. The goal is to help reduce concussions and head impact exposure.
Winston-Salem, North CarolinaAges 11–14 - NCT07020312RecruitingPhase 2
Brain training to improve muscle recovery after joint surgery
This trial tests whether brain-computer interface training can help you regain muscle control more effectively after knee or hip surgery. It focuses on four common procedures and uses neurofeedback to optimize muscle activation during recovery.
Chicago, IllinoisAges 18 years+ - NCT07136428RecruitingPhase 1/Phase 2
Asciminib for HER2+ breast cancer that has spread to the brain
This trial tests the drug asciminib for people with HER2-positive breast cancer that has spread to the brain and is growing. It may be an option if you have already tried standard treatments like T-DXd and tucatinib.
Durham, North CarolinaAges 18 years+ - NCT07585149Recruiting
Brain Biomarker Reference Levels in Healthy Newborns
This study collects blood samples and health information from healthy full-term newborns to establish normal ranges for brain-related markers in early life. Understanding these baseline levels may help doctors better identify babies who need extra care in the future.
CorkAges birth–1 week - NCT06429215Recruiting
Virtual reality and telemedicine to lower dementia risk
This trial tests whether a program using virtual reality and telemedicine can help lower the risk of memory decline and dementia in people who feel their thinking is slipping but don't have a diagnosed memory problem.
Rome, LazioAges 55–80 - NCT07318818RecruitingPhase 1/Phase 2
Revised cell therapy for recurrent brain cancer
This trial tests a new cell therapy (P134 cells) for people whose glioblastoma has come back after standard treatments like radiation or chemotherapy. The therapy uses a patient's own immune cells (PBMCs) to target cancer cells that have specific markers (CD44 or CD133). It also requires a small procedure to place a reservoir under the scalp for drug delivery.
BeijingAges 18–70 - NCT06058676Enrolling by invitation
Predicting blood flow changes after carotid stenting
This study looks at why some people have too much blood flow to the brain after a procedure to open a blocked neck artery. It uses special tests to check how well your brain controls its own blood flow, with the goal of predicting and preventing problems.
Beijing, Beijing MunicipalityAges 18–80 - NCT07500922Recruiting
Menopause effects on brain activity study
This study looks at how menopause affects brain signals controlling movement. It offers combined hormone treatment to eligible women.
JyväskyläAges 50–59 - NCT05994053Recruiting
Brain stimulation study for OCD symptoms
This study tests a gentle type of brain stimulation, called tACS, combined with brain-wave recording (EEG) to see if it can improve OCD symptoms. It's for adults with moderate-to-severe OCD who meet specific safety and health criteria.
Boston, MassachusettsAges 18 years+ - NCT07720622Recruiting
Motor learning vs muscle stimulation after stroke
This study compares two different therapies to help people regain movement after a recent stroke. It tests whether a motor relearning program or electric muscle stimulation works better for improving arm and leg function.
Lahore, Punjab ProvinceAges 40–65 - NCT07710040RecruitingPhase 1
Proton radiation before surgery for high-grade brain tumors
This trial tests proton radiation therapy given before surgery for people with a single, high-grade brain tumor. The goal is to see if pre-surgery radiation helps with treatment outcomes.
Obninsk, Kaluga OblastAges 18 years+ - NCT06742450Recruiting
Comparing two ways to stimulate the brain for Parkinson's
This trial compares two methods of deep brain stimulation (constant current vs constant voltage) for people with Parkinson's who already have the device placed but haven't turned it on yet. The goal is to see which method works better.
BeijingAges 18–75 - NCT07711990Recruiting
Studying ketone supplements and brain health
This trial tests how a ketone drink affects the brain in healthy middle-aged adults. It may help researchers understand if ketones can support brain function.
Columbus, OhioAges 45–65 - NCT07060651Recruiting
How the brain processes smells
This study looks at how different parts of the brain handle smells. It may help researchers better understand the sense of smell in people.
Chicago, IllinoisAges 18 years+
Common questions
- How many brain & nervous system clinical trials are recruiting?
- Clin2 is tracking 12,407 recruiting neurology studies from the U.S. registry right now, out of 19,276 we cover in this area in total.
- What does “Brain & nervous system” cover here?
- Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We group each study into brain & nervous system based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a brain & nervous system trial near me?
- Use the search to filter brain & nervous system studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.