Neurology
Brain & nervous system clinical trials
Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We’re tracking 12,407 recruiting studies in this area right now.
By phase
- Not applicable9,742
- Phase 2782
- Phase 1577
- Phase 3534
- Phase 4342
- Phase 1/Phase 2307
- Phase 2/Phase 3123
Top conditions
- Stroke843
- Parkinson Disease429
- Alzheimer Disease342
- Multiple Sclerosis342
- Dementia226
- Ischemic Stroke200
- Epilepsy197
- Obstructive Sleep Apnea156
- Spinal Cord Injuries153
- Insomnia152
- Sarcopenia150
- Traumatic Brain Injury150
- Acute Ischemic Stroke138
- Cerebral Palsy131
- Mild Cognitive Impairment129
- Migraine114
- Pain Management113
- Amyotrophic Lateral Sclerosis108
Leading sponsors
- Beijing Tiantan Hospital133
- Riphah International University125
- Assistance Publique - Hôpitaux de Paris112
- Mayo Clinic98
- Xuanwu Hospital, Beijing93
- VA Office of Research and Development92
- Hospices Civils de Lyon79
- Johns Hopkins University70
- National Taiwan University Hospital70
- University of Minnesota64
Where studies are running
- California680
- Massachusetts299
- New York292
- Florida274
- Texas267
- Maryland246
- Arizona213
- Alabama209
- Illinois189
- Pennsylvania177
Recruiting studies12,405 total
- NCT07708233RecruitingPhase 4
Benfotiamine vs vitamin B complex for diabetic nerve pain
This study compares two types of vitamin B supplements to see which one better relieves nerve pain and numbness in people with diabetes. It may help if you have diabetic neuropathy and are looking for a safe, non-drug option.
Pathumthani, BangkokAges 18 years+ - NCT04799288RecruitingPhase 1/Phase 2
Teriflunomide for HTLV-1 spinal cord stiffness and weakness
This early-phase trial tests whether teriflunomide can help people with HTLV-1 associated myelopathy (HAM) or tropical spastic paraparesis (TSP). It also checks safety and how well the treatment can be followed over time.
Bethesda, MarylandAges 18–120 - NCT06762184Recruiting
Pain scores in serious brain surgery patients after ICU care
This study looks back at patients who had brain surgery and were in the intensive care unit (ICU) for more than 24 hours. Researchers want to learn about their pain scores, which can help improve care for future patients.
Beijing, BeijingAges 18 years+ - NCT06958523Recruiting
Apple Health Study for US iPhone users
This study uses your iPhone and optional devices like Apple Watch to collect health data over time. It aims to discover how technology can help monitor and improve health.
Washington D.C., District of ColumbiaAges 18 years+ - NCT07275736RecruitingEarly Phase 1
CAR-T cell therapy for autoimmune diseases
This trial tests a treatment called CNCT19, a type of CAR-T cell therapy, for people with certain autoimmune diseases like neuromyelitis optica, myasthenia gravis, or multiple sclerosis that have come back or not responded to other treatments. It aims to see if targeting a specific immune cell (CD19) can help control the disease.
BeijingAges 18–75 - NCT07699393RecruitingPhase 2
Choline supplement study for healthy pregnancies
This trial tests whether taking extra choline (a nutrient similar to B vitamins) during pregnancy can improve health for mothers and babies. You may be eligible if you are early in a singleton pregnancy and do not drink alcohol.
Cape TownAges 18–45 - NCT04720365Recruiting
Home video game rehab to help Parkinson’s walking and balance
This trial tests whether a serious (therapeutic) home video-game program can improve walking and balance problems for people with Parkinson’s disease who still have trouble even with levodopa. It also looks at whether the approach is worth it in real-world care (cost and benefits).
BordeauxAges 18 years+ - NCT07262645RecruitingPhase 3
Light therapy for mild to moderate Alzheimer's disease
This study tests a near-infrared light therapy device for people with mild to moderate Alzheimer's disease. It may help with memory and thinking by using light on the head, a non-invasive approach.
Beijing, Beijing MunicipalityAges 50–85 - NCT07689747Recruiting
Brain training and ankle tests for athletes with weak ankles
This study tests if adding a special computer-based brain training activity to regular ankle function tests can help teenage and young adult athletes who have ongoing ankle problems. If you are a licensed football, basketball, or volleyball player aged 16–25 with chronic ankle instability for at least a year, you may be eligible.
Istanbul, SarıyerAges 16–25 - NCT07690527Enrolling by invitationPhase 1
Long-term follow-up for RB001 gene therapy in children with Phelan-McDermid syndrome
This study follows children who completed the RB001 gene therapy trial for Phelan-McDermid syndrome (caused by changes in the SHANK3 gene) to monitor their health and progress over a longer period of time.
Beijing, ChinaAges Any age - NCT07527104Recruiting
Bone marrow cells and rehabilitation for cerebral palsy in young children
This trial tests whether transplanting cells from a child's own bone marrow, combined with rehabilitation therapy, can improve movement and function in young children with cerebral palsy caused by birth-related brain injury or bleeding. The goal is to see if this approach helps children move better and become more independent.
Hanoi, HanoiAges 6 months–18 years - NCT06995638Recruiting
Multitasking training for older adults
This study tests whether a special online training program can help older adults improve their ability to multitask and stay focused. You'll do some computer exercises at home and come in for a few checkups, including a blood test.
Newark, New JerseyAges 60–75 - NCT07688538Recruiting
Mapping vision system development in embryos
This trial studies embryos to understand how the visual system develops normally and abnormally. It compares tissues from embryos with developmental problems to healthy ones, aiming to create a detailed map of early vision system growth.
Guangzhou, GuangdongAges Any age - NCT05699226Recruiting
Testing whether adjusting ECT treatment helps depression outcomes
This study tests a way of adjusting (titrating) ECT treatment to improve outcomes in people with major depression or bipolar II. It’s mainly for those who already need ECT with right-side electrode placement.
Albuquerque, New MexicoAges 50 years+ - NCT07686809Recruiting
Leg therapy for children with one-sided weakness
This study tests a new leg exercise program to help children with hemiplegia walk better. The therapy may improve balance and movement in the affected leg.
CairoAges 6–8 - NCT07683377Recruiting
Stent-assisted coil treatment for ruptured brain aneurysms
This trial tests if using a stent with coils to treat a ruptured brain aneurysm is safe and effective. It is for people who have a specific type of aneurysm (wide-necked, cystic) and are treated soon after the rupture.
Xi'an, ShaanxiAges 18–80 - NCT06701084Recruiting
Genetic Causes of Infant Epilepsy at Boston Children's
This study looks at the genetic causes of epilepsy that starts in babies under 1 year old. It aims to learn how a genetic diagnosis might help guide care.
Boston, MassachusettsAges Any age - NCT06982638Recruiting
Speeding up walking in Parkinson's with brain stimulation
This trial tests if a special type of brain stimulation (called TMS) can help people with Parkinson's disease who experience freezing of gait—when your feet feel stuck to the floor. The goal is to see if this treatment can improve walking and reduce those freezing episodes.
Charleston, South CarolinaAges 50–80 - NCT06767280Recruiting
Testing calf muscle in chronic nerve pain patients
This study looks at how a muscle in your calf (gastrocnemius) responds to a gentle electrical test in people with long-term nerve pain from the lower back. It aims to learn more about how the condition affects muscle function, which could help improve future treatments.
Sixth of October, Giza GovernorateAges 18–55 - NCT06973746Recruiting
Sitting up in a chair in the ICU for patients on breathing machines
This study tests whether getting patients who are on a breathing machine to sit in a chair helps them recover better. It looks at whether this simple activity can improve how well they get back to normal function.
Orléans, Centre-Val de LoireAges 18 years+ - NCT07673107RecruitingPhase 2
Botulinum toxin injection for essential tremor of hands and arms
This trial tests an investigational botulinum toxin injection (AGN-151607-DP) to reduce shaking in the hands and arms caused by essential tremor. It is for adults who have been diagnosed with this condition and who do not have certain nerve or muscle disorders.
Fresno, CaliforniaAges 18–85 - NCT06473285Recruiting
Esketamine for consciousness in prolonged disorders of consciousness
This trial tests whether a drug called esketamine can help improve brain activity in people with long-term disorders of consciousness. It may help doctors understand how the brain recovers.
BeijingAges 18–65 - NCT06056180Recruiting
Motor imagery training for balance in older adults
This study tests whether imagining moving your body (motor imagery training) can improve balance in older adults. It will compare this mental practice with usual activities to see if it helps prevent falls and improves stability.
Menteşe, MuğlaAges 60–80 - NCT07505914Recruiting
Breathing exercises for better thinking in older adults
This trial tests whether simple breathing exercises can improve memory and thinking skills in adults aged 65 and older. You would attend two sessions each week for 8 weeks.
IstanbulAges 65 years+
Common questions
- How many brain & nervous system clinical trials are recruiting?
- Clin2 is tracking 12,407 recruiting neurology studies from the U.S. registry right now, out of 19,276 we cover in this area in total.
- What does “Brain & nervous system” cover here?
- Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We group each study into brain & nervous system based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a brain & nervous system trial near me?
- Use the search to filter brain & nervous system studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.