Neurology
Brain & nervous system clinical trials
Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We’re tracking 12,406 recruiting studies in this area right now.
By phase
- Not applicable9,740
- Phase 2783
- Phase 1576
- Phase 3534
- Phase 4342
- Phase 1/Phase 2307
- Phase 2/Phase 3124
Top conditions
- Stroke841
- Parkinson Disease427
- Alzheimer Disease342
- Multiple Sclerosis341
- Dementia227
- Ischemic Stroke201
- Epilepsy197
- Obstructive Sleep Apnea156
- Insomnia154
- Spinal Cord Injuries153
- Traumatic Brain Injury150
- Sarcopenia149
- Acute Ischemic Stroke138
- Cerebral Palsy131
- Mild Cognitive Impairment130
- Migraine113
- Pain Management113
- Amyotrophic Lateral Sclerosis108
Leading sponsors
- Beijing Tiantan Hospital133
- Riphah International University125
- Assistance Publique - Hôpitaux de Paris112
- Mayo Clinic99
- Xuanwu Hospital, Beijing93
- VA Office of Research and Development92
- Hospices Civils de Lyon79
- Johns Hopkins University70
- National Taiwan University Hospital70
- University of Minnesota64
Where studies are running
- California681
- Massachusetts299
- New York292
- Florida275
- Texas265
- Maryland246
- Arizona212
- Alabama210
- Illinois188
- Pennsylvania177
Recruiting studies12,404 total
- NCT06765564Recruiting
Study of stem cell therapy for amyotrophic lateral sclerosis (ALS) progression
This study tests whether a new treatment using special motor neuron cells made from stem cells (iPSCs) can help people with ALS. The cells will be transplanted into the spinal cord to try to slow the disease and improve function.
Shanghai, Shanghai MunicipalityAges 18–60 - NCT07252011Recruiting
Brain stimulation study for mood swings
This study tests a non-invasive electrical stimulation method to help people with mood swings. It aims to improve mood stability and brain function.
Pittsburgh, PennsylvaniaAges 18–65 - NCT06577402Recruiting
Study on energy and protein in severe brain injury patients
This study measures how your body uses energy and protein if you are in the ICU with a severe brain injury while on a breathing machine. It can help doctors better understand your recovery needs.
Nanjing, JiangsuAges 18–85 - NCT06828471Recruiting
Social skills training for Huntington's disease
This study tests a social cognition training program for people with Huntington's disease and their caregivers. It aims to help improve social understanding and interactions.
Chicago, IllinoisAges 18–65 - NCT05763706Recruiting
Laser treatment for nerve pain after chemotherapy
This trial looks at whether light (photobiomodulation) and laser-like therapy can reduce nerve pain in people who developed neuropathy after chemotherapy. If you match the chemotherapy and language requirements, you may be screened to see if this treatment is safe and helpful for your symptoms.
Hasselt, LimburgAges 18 years+ - NCT06522581RecruitingPhase 1
Citicoline for brain injury in newborns
This trial tests if citicoline, a brain-protecting supplement, can help newborns with moderate to severe brain injury from lack of oxygen. It is for babies who have not gotten cooling treatment.
RawalpindiAges 1 day–4 weeks - NCT06464731Recruiting
Clot removal for mild stroke due to large artery blockage
This trial tests whether removing a blood clot from a large brain artery (using a catheter through the groin) can help people with mild stroke symptoms. It is for patients whose stroke started within the last 24 hours and who have a blockage in the front part of the brain's blood supply.
Zhangzhou, FujianAges 18–80 - NCT07572240Recruiting
Collagen Peptides for Memory and Focus in Stressed Adults
This study tests whether a collagen supplement (a protein derived from cows) can help improve attention, focus, and memory in adults aged 35–70 who feel stressed but are otherwise healthy. Researchers want to see if this supplement can help with mild cognitive complaints like trouble concentrating.
Nashik, MaharashtraAges 35–70 - NCT07244042Recruiting
Modified arm therapy for children recovering from stroke
This study compares two types of hand and arm therapy for children who have had a stroke. It tests whether adding special movement exercises to a commonly used therapy helps improve arm function better than the therapy alone.
Lahore, Punjab ProvinceAges 5–13 - NCT07244081Recruiting
Movement therapy for arm use in children with cerebral palsy
This study tests whether a type of physical therapy called kinesiotherapy can improve arm and hand function and daily living skills in children with hemiplegic cerebral palsy (weakness on one side). It may help children who can follow simple directions and participate in therapy sessions.
Sialkot, Punjab ProvinceAges 8–13 - NCT07239115RecruitingPhase 3
Levetiracetam to prevent seizures after brain tumor surgery
This trial tests whether the drug levetiracetam can prevent seizures in people who have brain tumor surgery. If you are having surgery to remove a brain tumor and have never had a seizure, this study may help keep you from having one after the operation.
BeijingAges 18–75 - NCT05563038Recruiting
Scrambler therapy for pain after stroke
This trial studies whether “scrambler therapy” can reduce ongoing pain in the body areas affected by a past stroke. It may help people who are at least a month past stroke and still have stroke-related pain.
Baltimore, MarylandAges 18 years+ - NCT07234890RecruitingPhase 2
Testing AV-001 to protect the brain during hemodialysis
This study tests a new medicine called AV-001 to see if it can protect the brain from damage caused by hemodialysis. If you qualify, you may help find a way to reduce thinking and memory problems linked to dialysis.
London, OntarioAges 18 years+ - NCT07228611Recruiting
Osteoporosis risk after stroke
This study looks at bone health in people who have had a stroke. It aims to find out who is at risk for weak bones (osteoporosis) after a stroke, so doctors can help prevent fractures.
Ankara, YenimahalleAges 55–85 - NCT07231419RecruitingPhase 3
Study of suzetrigine for diabetic nerve pain
This trial tests an experimental pain drug called suzetrigine for people with diabetic peripheral neuropathy (nerve damage from diabetes that causes pain in the feet and legs). It aims to see if the drug can safely reduce pain over time.
Birmingham, AlabamaAges 18–80 - NCT07226297Enrolling by invitationPhase 1/Phase 2
Personalized treatment for GARS1-related CMT2D
This trial tests a personalized medicine designed for a single person with a specific genetic mutation (GARS1) that causes Charcot-Marie-Tooth disease type 2D. The treatment is an antisense oligonucleotide, a custom-made molecule that targets the faulty gene.
Houston, TexasAges 13 years+ - NCT07223645Recruiting
Handgrip exercise and brain blood flow in young adults
This study tests whether a simple handgrip exercise program can improve blood flow regulation to the brain in young adults who are not very active. Participants will do handgrip exercises at home using a mobile app to track their progress.
Tallahassee, FloridaAges 18–35 - NCT06528379Recruiting
Physical activity to prevent thinking decline in older adults
This study tests whether a physical activity program can help prevent memory loss and disability in older Greek adults who have noticed some decline in their thinking. You can join if you have mild memory concerns but no dementia and are healthy enough to be active.
Pátrai, AchaiaAges 50 years+ - NCT05260619RecruitingPhase 2
Lenalidomide after response for primary brain lymphoma
This trial studies lenalidomide taken after your first treatment has worked for primary central nervous system lymphoma (PCNSL). It aims to help keep the lymphoma from coming back by testing lenalidomide as ongoing “maintenance” treatment.
Seongnam-si, Please SelectAges 19 years+ - NCT07218120Recruiting
Alzheimer's prevention study recruitment
This study is looking for adults aged 50 and older to join a web-based Alzheimer's prevention trial. If you don't have dementia and have email access, you may be able to participate.
Chula Vista, CaliforniaAges 50 years+ - NCT07217080Enrolling by invitation
Thalamic stimulation's effect on sleep brain waves
This trial studies how electrical stimulation in a deep brain area called the thalamus affects sleep brain waves. It may help people who already need brain recordings for medical reasons.
Boston, MassachusettsAges 5–85 - NCT07267559RecruitingPhase 4
Daridorexant and emotion brain testing study
This study tests a medication called daridorexant, which affects the brain's sleep-wake system, to see how it influences emotions and thinking. You will take one dose and complete computer tasks that measure how you process emotional information.
OxfordAges 18–40 - NCT06848166RecruitingEarly Phase 1
Middle meningeal artery embolization for resistant chronic migraine
This study tests a procedure called 'middle meningeal artery embolization' using a special glue-like material (SQUID) to treat chronic migraine that hasn't responded to other treatments. The goal is to see if blocking blood flow to the membrane around the brain can reduce migraine attacks.
Bishkek, BishkekAges 35–59 - NCT07209514Enrolling by invitation
Testing a spinal cord stimulator for diabetic nerve pain in the legs
This trial is studying a device called the Medtronic Inceptiv™ Closed-Loop DTM Spinal Cord Stimulator to see if it can help reduce pain from diabetic peripheral neuropathy (nerve damage caused by diabetes) in the lower legs. It is for people whose pain has lasted at least 6 months and hasn't been helped by other treatments.
Grand Island, NebraskaAges 19 years+
Common questions
- How many brain & nervous system clinical trials are recruiting?
- Clin2 is tracking 12,406 recruiting neurology studies from the U.S. registry right now, out of 19,323 we cover in this area in total.
- What does “Brain & nervous system” cover here?
- Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We group each study into brain & nervous system based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a brain & nervous system trial near me?
- Use the search to filter brain & nervous system studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.