Neurology
Brain & nervous system clinical trials
Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We’re tracking 11,941 recruiting studies in this area right now.
By phase
- Not applicable9,343
- Phase 2764
- Phase 1557
- Phase 3513
- Phase 4339
- Phase 1/Phase 2300
- Phase 2/Phase 3125
Top conditions
- Stroke796
- Parkinson Disease395
- Alzheimer Disease338
- Multiple Sclerosis329
- Dementia226
- Epilepsy193
- Ischemic Stroke190
- Insomnia159
- Traumatic Brain Injury151
- Obstructive Sleep Apnea142
- Spinal Cord Injuries142
- Acute Ischemic Stroke139
- Sarcopenia135
- Mild Cognitive Impairment127
- Cerebral Palsy119
- Pain Management114
- Migraine107
- Fibromyalgia104
Leading sponsors
- Beijing Tiantan Hospital124
- Assistance Publique - Hôpitaux de Paris109
- Riphah International University105
- Mayo Clinic98
- VA Office of Research and Development92
- Xuanwu Hospital, Beijing89
- Hospices Civils de Lyon77
- Johns Hopkins University69
- University of Minnesota63
- Washington University School of Medicine63
Where studies are running
- California659
- Massachusetts305
- New York294
- Florida271
- Texas266
- Maryland248
- Alabama207
- Arizona207
- Illinois181
- Pennsylvania176
Recruiting studies11,941 total
- NCT07713706Enrolling by invitation
Brain activity study for speech production
This study looks at how the brain stops speech, using electrical recordings taken during your already-planned epilepsy monitoring. It may help understand speech control.
Pittsburgh, PennsylvaniaAges 8–26 - NCT07715006Recruiting
Spinal nerve stimulation for children with cerebral palsy
This study adds a mild electrical stimulation to the spinal nerves during a planned SDR surgery for children with cerebral palsy, to see if it helps improve movement more than the surgery alone.
Pittsburgh, PennsylvaniaAges 3–14 - NCT07707076Recruiting
Flow diverter vs standard treatment for wide-neck brain aneurysms
This trial compares a flow diverter device to standard endovascular treatment for unruptured wide-neck brain aneurysms at a bifurcation. If you have this type of aneurysm, this study may help determine which treatment works better.
Guangzhou, GuangdongAges 18–75 - NCT07707830Recruiting
Thyroid and body health assessment for adults with low thyroid function
This study looks at how an underactive thyroid (hypothyroidism) affects internal organs, muscles, and bones. It uses ultrasound and physical measurements to understand these effects, which may help improve care.
AndijanAges 18–59 - NCT07713121Recruiting
Keeping blood pressure up during surgery to prevent confusion in older adults
This trial tests whether keeping blood pressure at 85 mmHg or higher during surgery can reduce confusion (delirium) after surgery. It is for older adults with high blood pressure who are having non-cardiac surgery.
HamburgAges 65 years+ - NCT06636578RecruitingPhase 4
Adding dexmedetomidine to pain block for heart surgery
This study tests adding a medicine called dexmedetomidine to a standard pain-blocking injection (ropivacaine) used during heart surgery. The goal is to see if it reduces pain and speeds recovery better than the injection alone.
Al FayyumAges 20–65 - NCT06643013Recruiting
Targeting brain blood vessels to help small vessel disease
This study tests a drug that targets a protein called TSPO to see if it can improve the function of the cells lining the small blood vessels in the brain of people with cerebral small vessel disease. It may help with mild memory or thinking problems.
LondonAges 60–90 - NCT05811013Recruiting
Static magnetic brain stimulation for progressive multiple sclerosis
This trial studies whether a noninvasive brain stimulation approach using a static magnetic field can help people with progressive multiple sclerosis. It aims to improve progressive nerve function while keeping other treatments stable.
Pozzilli, IserniaAges 18–65 - NCT06639009Recruiting
Laser treatment for better mouth opening in oral fibrosis
This study tests if a special laser therapy (photobiomodulation) helps people with oral submucous fibrosis open their mouths wider. It's for people who haven't had other treatments for this condition in the last three months.
New Delhi, National Capital Territory of DelhiAges 18–99 - NCT06639802Recruiting
Therapy for balance and coordination in ataxic cerebral palsy
This trial tests a hand-arm and leg therapy program to improve balance and coordination in children with ataxic cerebral palsy. It may help your child move more steadily and confidently.
RawalpindiAges 6–15 - NCT05951101Recruiting
Device to close an irregular heartbeat heart pocket safely
This trial tests the Zenith system, a device that seals off a heart area called the left atrial appendage to reduce stroke risk in people with atrial fibrillation (AF). You may be eligible if you have AF and a doctor recommends LAA closure, and you can return for follow-up scans and visits.
Parkville, VictoriaAges 18 years+ - NCT06146062RecruitingPhase 2
Stem cell therapy for severe traumatic brain injury
This trial tests whether a single infusion of stem cells from donated umbilical cord tissue can help calm inflammation in the brain after severe traumatic brain injury. It is for patients aged 18–50 who need brain pressure monitoring and are not responding to verbal commands 5 days after sedation is stopped.
ClamartAges 18–50 - NCT06457217Recruiting
MRSI for minor stroke with large artery blockage
This study uses a special MRI technique (called MRSI) to look at brain chemistry in people who have had a minor stroke due to a blocked large artery. The goal is to see if the scan can help doctors better understand the stroke and guide treatment decisions.
Shanghai, Shanghai MunicipalityAges 18–100 - NCT06644807Recruiting
Neuromodulation for phantom limb pain after amputation
This trial tests a new approach to suppress phantom limb pain using neuromodulation methods. It may help people who have had a limb amputated and continue to experience persistent pain.
Moscow, MoscowAges 18–65 - NCT06645405Recruiting
AI scan reading for stroke caused by large vessel blockage
This trial tests whether an AI program can better read CT scans to find large blood vessel blockages that cause stroke. If you had a stroke from a blocked large vessel and already had CT scans, the AI may help doctors decide on treatment faster.
Shanghai, Shanghai MunicipalityAges 18–95 - NCT04981184Recruiting
Testing muscle signals to predict walking recovery after stroke
This study looks at surface muscle electrical signals (from electrodes on the skin) to understand and predict how well your balance and walking may improve after a first stroke. You might benefit by learning more about your recovery and by helping researchers find better ways to track progress.
KaunasAges 18–89 - NCT05724719Recruiting
Study brain signals after a first unprovoked seizure
This study looks at people ages 18 to 65 after they have a first seizure that is not clearly triggered. It also compares them with healthy volunteers to better understand what might predict whether seizures come back.
Halifax, Nova ScotiaAges 18–65 - NCT07699094Recruiting
Predicting blood pressure changes in spinal cord injury
This study uses a simple finger sensor to monitor blood pressure regulation in people with spinal cord injury. It aims to find a new way to predict and manage blood pressure issues.
The Bronx, New YorkAges 18–75 - NCT06646601Recruiting
Garden-based program for heart and stroke recovery
This trial tests a preventive program that uses a therapeutic garden to help people with heart or blood vessel conditions. It looks at whether patients find the program helpful and easy to take part in.
GapAges 18 years+ - NCT06454591Recruiting
Using fast MRI to understand brain injury recovery
This study uses a quick MRI scan to check brain function and predict recovery after a traumatic brain injury. It may help researchers develop better ways to assess and treat TBI patients.
Calgary, AlbertaAges 18 years+ - NCT07704099RecruitingPhase 2
Study of KER-065 for Duchenne Muscular Dystrophy
This study tests a new medication called KER-065 to see if it helps people with Duchenne Muscular Dystrophy (DMD). It may help boys and men who are still walking, as well as those who use a wheelchair, as long as they are on a stable corticosteroid treatment.
Auckland, North IslandAges 9 years+ - NCT07704931Enrolling by invitation
Can spinal cord stimulation repair small nerve fibers?
This study tests whether a special type of spinal cord stimulation (which uses mild electrical pulses to block pain) can help repair damaged small nerve fibers in people with small fiber neuropathy. If you have chronic nerve pain and meet the criteria, you may be able to join.
Grand Island, NebraskaAges 19 years+ - NCT07701161Recruiting
At-home blood test for Alzheimer's disease
This study is developing a simple finger-prick test you can do at home to measure a blood marker related to Alzheimer's disease. It aims to make checking for Alzheimer's easier and more convenient.
Chicago, IllinoisAges 40–90 - NCT07698951Recruiting
Testing a new device to close PFO after stroke
This trial tests a new device to close a PFO (a small hole in the heart) in people who have had a stroke caused by a blood clot passing through that hole. The goal is to see if the device can prevent another stroke.
BelgradeAges 18–65
Common questions
- How many brain & nervous system clinical trials are recruiting?
- Clin2 is tracking 11,941 recruiting neurology studies from the U.S. registry right now, out of 18,432 we cover in this area in total.
- What does “Brain & nervous system” cover here?
- Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We group each study into brain & nervous system based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a brain & nervous system trial near me?
- Use the search to filter brain & nervous system studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.