Neurology
Brain & nervous system clinical trials
Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We’re tracking 12,406 recruiting studies in this area right now.
By phase
- Not applicable9,740
- Phase 2783
- Phase 1576
- Phase 3534
- Phase 4342
- Phase 1/Phase 2307
- Phase 2/Phase 3124
Top conditions
- Stroke841
- Parkinson Disease427
- Alzheimer Disease342
- Multiple Sclerosis341
- Dementia227
- Ischemic Stroke201
- Epilepsy197
- Obstructive Sleep Apnea156
- Insomnia154
- Spinal Cord Injuries153
- Traumatic Brain Injury150
- Sarcopenia149
- Acute Ischemic Stroke138
- Cerebral Palsy131
- Mild Cognitive Impairment130
- Migraine113
- Pain Management113
- Amyotrophic Lateral Sclerosis108
Leading sponsors
- Beijing Tiantan Hospital133
- Riphah International University125
- Assistance Publique - Hôpitaux de Paris112
- Mayo Clinic99
- Xuanwu Hospital, Beijing93
- VA Office of Research and Development92
- Hospices Civils de Lyon79
- Johns Hopkins University70
- National Taiwan University Hospital70
- University of Minnesota64
Where studies are running
- California681
- Massachusetts299
- New York292
- Florida275
- Texas265
- Maryland246
- Arizona212
- Alabama210
- Illinois188
- Pennsylvania177
Recruiting studies12,404 total
- NCT04871035Recruiting
Compare immunoadsorption vs plasma exchange for Guillain-Barré
This study tests whether immunoadsorption works as well as plasma exchange to improve symptoms in people with Guillain-Barré syndrome. The goal is to find which treatment helps recovery and is safer for patients.
Ulm, Baden-WurttembergAges 18 years+ - NCT07253532Recruiting
Vibration belt study for improving balance and walking
This study tests a belt that vibrates to help with balance and walking. It may help people with balance problems due to conditions like ataxia or inner ear issues.
Baltimore, MarylandAges 18–80 - NCT07468110Recruiting
Nutrition and balance in chronic stroke survivors
This study looks at how a simple blood test (the CONUT score, which measures nutrition and immune health) relates to balance and daily function in people who have had a stroke a long time ago. It may help find ways to improve recovery and quality of life.
Istanbul, PendikAges 18–85 - NCT05541705Recruiting
Treadmill training to improve weight shifting after stroke
This trial tests a specialized treadmill walking program to improve how well you transfer your weight from one leg to the other during walking after a stroke. It may help with more balanced, safer steps by training your gait pattern.
Austin, TexasAges 18 years+ - NCT05872191Enrolling by invitation
Spanish-language tests for arm function after stroke
This study checks whether two hand/arm assessment questionnaires and tests work well in Spanish for people living with stroke-related arm weakness. It mainly involves you doing standardized assessments if you’re eligible.
Valencia, ValenciaAges 18–80 - NCT07208734Enrolling by invitation
Personalized brain stimulation for memory loss in older adults
This trial tests a personalized brain stimulation treatment for older adults with mild memory or thinking problems caused by Alzheimer's disease. It aims to see if tailored stimulation can improve cognitive function.
Beijing, Beijing MunicipalityAges 50–90 - NCT07208279Recruiting
Cognitive Vitality Study: Can Axolt help memory?
This clinical trial is testing whether a special dietary supplement called Axolt can help keep your memory and thinking sharp as you get older. It is for healthy adults 55 and older who live independently and have no major memory problems.
West Palm Beach, FloridaAges 55 years+ - NCT07208162Recruiting
SHARE program for African American families facing memory loss
This study tests a program called SHARE, which helps African American families work together when a loved one has early-stage memory loss. It focuses on improving communication and support at home.
Cleveland, OhioAges 18 years+ - NCT07206797Recruiting
Ultrasound to measure muscle activity from spinal cord stimulation
This study uses ultrasound to see how muscles respond to two types of electrical stimulation (spinal cord and functional electrical stimulation). It may help researchers better understand how to treat muscle weakness or paralysis.
Raleigh, North CarolinaAges 18–60 - NCT06381570RecruitingEarly Phase 1
Vinblastine and tovorafenib for recurring pediatric low-grade glioma
This trial is testing a combination of two drugs, vinblastine and tovorafenib, for children and young adults (up to age 25) whose low-grade glioma has come back or worsened after prior treatment. It is for people whose tumor has a specific change in a gene called BRAF or CRAF.
Toronto, OntarioAges birth–25 years - NCT06814964RecruitingPhase 1
Intraventricular clot removal with medication after brain bleed
This trial tests a clot-busting drug (rhTNK-tPA) to remove blood from the ventricles (fluid spaces deep in the brain) after a spontaneous brain bleed. It may help patients whose ventricles are blocked by a large clot, reducing pressure and improving recovery.
Beijing, Beijing MunicipalityAges 18–80 - NCT03514524Enrolling by invitation
PET-MRI brain scans for recent injury, stroke, or mild memory changes
This study uses special brain scans to measure proteins and connections in the brain after a recent injury, stroke, or in people with mild memory/behavior changes. The goal is to understand brain changes and how they relate to symptoms, which may help future diagnosis and treatment.
LeuvenAges 18–80 - NCT07200726Recruiting
Brain inflammation and thinking after heart surgery
This study looks at whether brain inflammation during heart surgery may affect memory and thinking. It includes people aged 60 and older who are having planned heart surgery.
Genk, LimburgAges 60 years+ - NCT07198438Enrolling by invitation
Deep vs standard brain stimulation for depression
This trial compares two types of brain stimulation (deep vs standard theta burst stimulation) to see which works better for people with depression who haven't gotten enough help from antidepressant medication. It aims to find a more effective treatment option.
Douliu, Yunlin CountyAges 18–70 - NCT07197970RecruitingPhase 3
Stent for blocked brain arteries
This trial tests whether a drug-coated stent can help people with severely narrowed brain arteries that have already caused a stroke or mini-stroke. It aims to improve blood flow and prevent future strokes.
Beijing, Beijing MunicipalityAges 18–80 - NCT07197099Recruiting
Plasma exchange for immune-related nerve diseases
This study looks at whether removing and replacing blood plasma (called therapeutic plasma exchange or TPE) can help people with immune-related nerve or brain conditions. It includes both new and returning cases that meet standard guidelines for this treatment.
CairoAges Any age - NCT06803823RecruitingPhase 2
Testing a new drug for agitation in Alzheimer's
This study tests an experimental drug, ONO-2020, to see if it can help reduce agitation in people with Alzheimer's disease. Agitation can include restlessness, pacing, or verbal outbursts, and this trial aims to find a new treatment option.
AichiAges 55–90 - NCT06541015Recruiting
TENS for improving walking after stroke
This study tests whether a small electrical device (TENS) can help stroke survivors walk better. You will receive TENS or placebo while walking on a treadmill, and the researchers will measure how your muscles respond.
Dallas, TexasAges 18–80 - NCT04763356Recruiting
Remote monitoring to manage nerve pain after chemotherapy
This study tests whether remote check-ins (via phone/app/website) can help manage chemotherapy-related nerve pain in the hands and feet. It enrolls adults who developed nerve symptoms after certain cancer medicines and need ongoing monitoring.
Salt Lake City, UtahAges 18 years+ - NCT07638579Enrolling by invitation
Nerve monitoring methods during thyroid and parathyroid surgery
This study compares two ways to monitor nerves during thyroid or parathyroid surgery to see which method works better. During surgery, doctors use electrical sensors to make sure they don't accidentally damage important nerves in your neck.
ThessalonikiAges Any age - NCT07190365Recruiting
Goal-oriented telehealth rehab for veterans with brain injury
This trial tests a telehealth program to help veterans with long-term thinking and planning problems after a mild to moderate brain injury. It aims to improve your daily life and community involvement.
Palo Alto, CaliforniaAges 18–65 - NCT07374393Enrolling by invitation
Sleep study for people with brain disorders
This study looks at sleep and sleep problems in people with neurological conditions like stroke, Parkinson's, epilepsy, or memory issues. You will do a one-night sleep test (polysomnography) and answer questionnaires to help researchers understand your sleep and daytime function.
Changchun, JilinAges 14–80 - NCT06521437Enrolling by invitation
How the brain's memory center works in epilepsy
This study looks at how the hippocampus (a part of the brain important for memory) works in people with epilepsy. If you have a hard-to-treat type of epilepsy called MTLE, this research may help doctors understand memory and brain function better.
Chicago, IllinoisAges 18 years+ - NCT07183761RecruitingPhase 2
Stem cell therapy for diabetic nerve pain
This study tests whether umbilical cord stem cells can help people with diabetic nerve damage in their legs who haven't gotten enough relief from standard treatments. It aims to improve symptoms like numbness, pain, and tingling.
Chongqing, Chongqing MunicipalityAges 18–80
Common questions
- How many brain & nervous system clinical trials are recruiting?
- Clin2 is tracking 12,406 recruiting neurology studies from the U.S. registry right now, out of 19,323 we cover in this area in total.
- What does “Brain & nervous system” cover here?
- Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We group each study into brain & nervous system based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a brain & nervous system trial near me?
- Use the search to filter brain & nervous system studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.