Gastroenterology
Digestive system clinical trials
Conditions of the stomach, intestines, liver, and the rest of the digestive tract. We’re tracking 7,606 recruiting studies in this area right now.
By phase
- Not applicable4,686
- Phase 21,188
- Phase 1568
- Phase 3457
- Phase 1/Phase 2368
- Phase 4229
- Phase 2/Phase 3110
Top conditions
- Colorectal Cancer479
- Pancreatic Cancer287
- Gastric Cancer283
- Hepatocellular Carcinoma256
- Esophageal Cancer189
- Rectal Cancer168
- Breast Cancer146
- Crohn Disease134
- Ulcerative Colitis129
- Hepatocellular Carcinoma (HCC)114
- Colon Cancer112
- Liver Cancer99
- Lung Cancer95
- Inflammatory Bowel Diseases94
- Pancreas Cancer91
- Ovarian Cancer89
- Esophageal Squamous Cell Carcinoma86
- Cystic Fibrosis77
Leading sponsors
- Fudan University101
- Sun Yat-sen University85
- Mayo Clinic75
- Chinese University of Hong Kong56
- Second Affiliated Hospital, Zhejiang University, School of Medicine56
- M.D. Anderson Cancer Center55
- Assistance Publique - Hôpitaux de Paris53
- Sixth Affiliated Hospital, Sun Yat-sen University51
- National Cancer Institute (NCI)49
- National Taiwan University Hospital45
Where studies are running
- California438
- Arizona190
- Texas140
- Alabama129
- Florida128
- New York120
- Massachusetts119
- Maryland88
- Ohio79
- Illinois69
Recruiting studies7,606 total
- NCT07109180Recruiting
Robot vs. open surgery for chronic pancreatitis pain
This study compares robot-assisted vs. open surgery for treating chronic pancreatitis pain. It aims to see which approach works better for people with a dilated pancreatic duct who need relief from severe symptoms.
AmsterdamAges 18 years+ - NCT07111572Recruiting
Can gut markers show early if a UC treatment works?
This study looks at stool samples to see if certain markers can quickly tell whether a biologic medicine is starting to work for moderate-to-severe ulcerative colitis. If successful, this could help doctors make faster, smarter treatment decisions.
Jinan, ShandongAges 18–75 - NCT07114939RecruitingPhase 1
A new pet scan for pancreatic neuroendocrine tumors
This study is testing a special type of PET/CT scan using a tracer called FTT to see if it can better find and track pancreatic neuroendocrine tumors that have spread or cannot be removed by surgery. The goal is to improve imaging for people with this type of cancer.
Philadelphia, PennsylvaniaAges 18 years+ - NCT07110064RecruitingPhase 2
A new combo therapy for advanced pancreatic cancer
This trial tests a combination of three drugs (QL1706, lenvatinib, and chemotherapy) as the first treatment for people with advanced pancreatic cancer that has spread to other parts of the body. It aims to see if this combination is safe and effective.
NanjingAges 18 years+ - NCT07108075Recruiting
Testing metformin and carvedilol for cirrhosis with variceal bleeding
This trial tests whether adding metformin to carvedilol (a standard drug) lowers liver pressure more than carvedilol alone in people with cirrhosis who have had variceal bleeding. The goal is to prevent future bleeding.
New Delhi, National Capital Territory of DelhiAges 18–75 - NCT07107815Enrolling by invitation
Predicting rectal cancer treatment response using MRI
This study uses advanced MRI scanning and computer analysis to predict how well rectal cancer might respond to treatments given before surgery. It may help doctors choose the best approach for you.
Beijing, Beijing MunicipalityAges Any age - NCT07114380Recruiting
Cold snare removal of medium colon polyps
This trial tests a way to remove medium-sized colon polyps (10–20 mm) that have a stalk, using a cold snare (a wire loop that cuts without heat). It may help you avoid more complex procedures, and the study will check if this method is safe and effective.
HsinchuAges 20 years+ - NCT07111273Recruiting
Predicting relapse in ulcerative colitis with early stool tests
This study looks at whether early stool tests (fecal immunochemical test and calprotectin) can predict when ulcerative colitis symptoms might return. It is for people who have never taken biologic medications.
Jinan, ShandongAges 18–75 - NCT07114055RecruitingPhase 2/Phase 3
Ebastine for diarrhea-predominant IBS
This trial tests whether ebastine, an allergy medicine, can help relieve symptoms of diarrhea-predominant irritable bowel syndrome (IBS-D). If you have IBS-D and are at least 18, this study may offer a new option to manage your condition.
DhakaAges 18 years+ - NCT07115134Recruiting
New dressing for feeding tube after placement
This trial tests a new type of dressing (bandage) designed to keep a gastrostomy feeding tube secure after it is placed in the stomach. It may help reduce movement and improve healing for children who have just had this surgery.
Washington D.C., District of ColumbiaAges 7–21 - NCT07111715Recruiting
AI vs. standard reading for suspected Crohn disease
This study tests whether an artificial intelligence (AI) system can help doctors find signs of Crohn's disease better than standard reading of capsule endoscopy images. It is for people who have symptoms that might be Crohn's but whose colonoscopy didn't clearly show the problem.
Brescia, BresciaAges 18–75 - NCT07106827RecruitingPhase 1
Study of a new drug for advanced or resistant solid tumors
This trial tests a new drug, GV20-0251, for people with advanced solid tumors that have not responded to standard treatments. It aims to see if the drug is safe and helpful.
Chengdu, SichuanAges 18 years+ - NCT07107750RecruitingPhase 1
New drug combo for untreated advanced bile duct cancer
This trial tests a new targeted drug (emavusertib) combined with standard chemotherapy and immunotherapy for people with advanced bile duct or gallbladder cancer that hasn't been treated before. It aims to see if this combination is safe and effective.
St Louis, MissouriAges 18 years+ - NCT07108855RecruitingPhase 1/Phase 2
Green dye to guide early cancer removal
This trial tests whether a special dye (indocyanine green) given through a vein can help doctors see the exact edges and depth of early-stage esophageal or stomach cancer during a minimally invasive procedure to remove it. If you are scheduled for this procedure, the dye may help the surgeon remove the cancer more precisely.
Groningen, Provincie GroningenAges 18 years+ - NCT07114159Recruiting
Sacral nerve stimulation for ulcerative colitis
This trial tests if sacral nerve stimulation can safely help people with ulcerative colitis that hasn't improved with standard treatments. It aims to see if this approach can reduce symptoms and improve quality of life.
Xi'an, ShaanxiAges 18–65 - NCT07112690Recruiting
Nerve block for radiation pain during anal cancer treatment
This study tests a nerve block procedure (ganglion impar neurolysis) to reduce severe pain caused by radiation therapy for anal or perianal skin cancer. It may help you manage pain while you continue your cancer treatment.
Atlanta, GeorgiaAges 18 years+ - NCT07108517Recruiting
Post-traumatic growth program for cancer survivors in Greece
This trial tests a guided program to help people with breast, colorectal, or head and neck cancer find personal growth after finishing chemotherapy. It is for those who have completed their planned treatment within the last 5 years and are not currently in other psychological care.
ThessalonikiAges 18–80 - NCT07108348Recruiting
ADAR1 levels in rectal cancer
This study looks at a protein called ADAR1 in rectal cancer tissue. It aims to see how ADAR1 levels might be related to the cancer and help doctors understand the disease better.
Konya, MeramAges 18–90 - NCT07107633RecruitingPhase 2
Imaging test for cancer spread in the abdomen
This trial tests a special imaging injection to see if it can better detect cancer that has spread to the lining of the abdomen in people with stomach or bowel cancer. If you are scheduled for surgery to remove or explore the cancer, this scan might help your doctor plan the best treatment.
ShanghaiAges 18 years+ - NCT07113275RecruitingPhase 3
Short versus long radiation schedule for advanced rectal cancer
This study compares two different schedules of radiation (a short course versus a longer course) followed by standard chemotherapy and immunotherapy for advanced rectal cancer. It aims to see which approach works best to shrink the tumor before surgery.
Wuhan, HubeiAges 18–75 - NCT07109583Recruiting
Does dinner timing affect health and behavior?
This study looks at how the time you eat dinner may influence your sleep, daily habits, and overall health. It tests whether having dinner earlier or later changes how your body works.
TaipeiAges 20–50 - NCT07111221Recruiting
Reducing bleeding risk before liver transplant
This trial tests a procedure to lower blood loss during liver transplant for patients with high blood pressure in the liver. It may help those who have had a previous transplant, abdominal surgery, or certain complications of liver disease.
WarsawAges 18 years+ - NCT06307925RecruitingPhase 1
HC010 for advanced solid tumors: a safety and early efficacy study
This trial is testing a new drug (HC010) for people with advanced solid tumors that have not responded to standard treatments. It aims to see if the drug is safe, how it works in the body, and whether it can shrink tumors.
Guangzhou, GuangdongAges 18–75 - NCT06332274RecruitingPhase 3
Tislelizumab for cancer patients with minimal residual disease
This trial is for people who have completed standard cancer treatments (like surgery, chemo or radiation) and have no visible cancer on scans, but may still have very small amounts of cancer DNA in their blood. The study tests whether the drug tislelizumab can help prevent the cancer from coming back.
Villejuif, Val De MarneAges 18 years+
Common questions
- How many digestive system clinical trials are recruiting?
- Clin2 is tracking 7,606 recruiting gastroenterology studies from the U.S. registry right now, out of 12,023 we cover in this area in total.
- What does “Digestive system” cover here?
- Conditions of the stomach, intestines, liver, and the rest of the digestive tract. We group each study into digestive system based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a digestive system trial near me?
- Use the search to filter digestive system studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Mental health
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.