Gastroenterology
Digestive system clinical trials
Conditions of the stomach, intestines, liver, and the rest of the digestive tract. We’re tracking 7,874 recruiting studies in this area right now.
By phase
- Not applicable4,909
- Phase 21,178
- Phase 1584
- Phase 3466
- Phase 1/Phase 2389
- Phase 4235
- Phase 2/Phase 3113
Top conditions
- Colorectal Cancer495
- Gastric Cancer297
- Pancreatic Cancer294
- Hepatocellular Carcinoma283
- Esophageal Cancer191
- Rectal Cancer174
- Breast Cancer146
- Crohn Disease144
- Ulcerative Colitis141
- Colon Cancer113
- Inflammatory Bowel Diseases108
- Hepatocellular Carcinoma (HCC)103
- Liver Cancer99
- Lung Cancer98
- Pancreas Cancer94
- Ovarian Cancer90
- Esophageal Squamous Cell Carcinoma88
- Cystic Fibrosis78
Leading sponsors
- Fudan University104
- Sun Yat-sen University89
- Mayo Clinic75
- Chinese University of Hong Kong60
- M.D. Anderson Cancer Center59
- Second Affiliated Hospital, School of Medicine, Zhejiang University57
- Assistance Publique - Hôpitaux de Paris55
- Sixth Affiliated Hospital, Sun Yat-sen University50
- National Taiwan University Hospital49
- Cancer Institute and Hospital, Chinese Academy of Medical Sciences48
Where studies are running
- California465
- Arizona175
- Texas146
- Florida134
- Massachusetts128
- New York123
- Alabama121
- Maryland86
- Ohio78
- Pennsylvania72
Recruiting studies7,874 total
- NCT06468917Recruiting
Removing drains early after pancreatic surgery
This trial tests whether removing surgical drains on the first day after surgery is better than waiting longer. If you are having pancreatic surgery and are at low risk for complications, this study may help reduce discomfort and recovery time.
Peschiera del Garda, VeronaAges 18–85 - NCT06474637Recruiting
Powered handle sleeve gastrectomy study
This trial tests a new powered handle tool that doctors use during sleeve gastrectomy surgery to help people lose weight. It is for patients having this surgery for the first time.
KaunasAges 18–65 - NCT06448494Recruiting
Geriatric care before and after surgery for older adults
This study looks at how well new geriatric units help older adults recover after certain digestive and urological surgeries in the Paris area. If you are 75 or older and having one of the listed surgeries, this may apply to you.
Paris, IIe-de-FranceAges 75 years+ - NCT06696261RecruitingPhase 3
Lianxiaxiaopi granules for post-meal fullness
This study tests a Chinese herbal granule (Lianxiaxiaopi) for people with postprandial distress syndrome, a condition where you feel full too soon or uncomfortably full after eating. The goal is to see if it helps reduce these symptoms.
Beijing, Beijing MunicipalityAges 18–65 - NCT06364735Recruiting
Celiac disease and catch-up growth in children
This study looks at how children with celiac disease grow after starting a gluten-free diet. It focuses on children diagnosed at a specific hospital in Milan to understand what helps them catch up in growth.
MilanAges 18 years+ - NCT06523179Recruiting
Liver cancer risk study for people with fatty liver disease
This study looks at your risk of developing liver cancer (hepatocellular carcinoma) if you have a liver condition such as NAFLD or a related disease. It aims to improve how doctors predict who might be at higher risk, so they can offer better monitoring and care.
Milan, MilanoAges 45–75 - NCT06454149Recruiting
Study of gastric MALT lymphoma
This study is looking at people with a rare stomach lymphoma (MALT lymphoma) or people with other stomach conditions. It aims to understand more about the disease and track outcomes over time.
Ansan-si, Gyeonggi-doAges 18–75 - NCT06461559RecruitingPhase 1/Phase 2
Bowel training before ileostomy reversal
This study tests whether infusing liquid into the bowel through the stoma before surgery can help prepare the gut. It is for people with a loop ileostomy who are planning to have it reversed.
La Jolla, CaliforniaAges 18–80 - NCT06463366Recruiting
Using MRI to better diagnose liver fat, inflammation, and scarring
This study uses advanced MRI scans to get a clearer picture of liver fat, inflammation, and scarring in people with chronic liver disease. It aims to help doctors diagnose and understand liver problems better.
Shenyang, LiaoningAges 18–75 - NCT06462742Recruiting
Microwave ablation vs. surgery for intrahepatic cholangiocarcinoma
This trial compares two treatments for a liver cancer called intrahepatic cholangiocarcinoma—surgery to remove the tumor versus microwave ablation, which uses heat to destroy cancer cells. It tests if ablation works as well as surgery for people with small tumors that haven't spread.
Beijing, Beijing MunicipalityAges 18 years+ - NCT06382493Recruiting
Tegoprazan sequential therapy for H. pylori infection
This study tests a new treatment plan using a medicine called tegoprazan for people with H. pylori, a bacteria that can cause stomach ulcers. The goal is to see if this sequential treatment works better at clearing the infection.
Seongnam-si, Gyeonggi-doAges 18 years+ - NCT06298409RecruitingPhase 1
Rifaximin for SIBO: Gut Bacteria Study
This study tests how Rifaximin (a medicine for SIBO) affects the bacteria and other substances in your gut. You'll swallow a small capsule that collects samples as it travels through your digestive system, so researchers can see how your gut changes during treatment.
Mountain View, CaliforniaAges 18–80 - NCT06444633Recruiting
Home delivery of diarrhea treatment for children under 5
This trial tests whether sending ORS (oral rehydration solution) and zinc tablets to homes ahead of time helps treat diarrhea in young children faster. It's for caregivers in Nigeria who speak English or Hausa and have a child under 5.
AbujaAges 15 years+ - NCT06402864RecruitingPhase 3
Internal radiation for rectal preservation in intermediate rectal cancer
This study is testing whether a special internal radiation treatment (contact X-ray brachytherapy) can help people with intermediate-stage rectal cancer avoid surgery and keep their rectum intact. It is for patients who are also receiving mFolfirinox chemotherapy.
Avignon, FranceAges 18–99 - NCT06279351RecruitingPhase 2
Thalidomide plus standard chemo and cetuximab for left-sided colon cancer
This trial tests whether adding the drug thalidomide to standard chemotherapy plus cetuximab can work better for people with advanced left-sided colorectal cancer that hasn't been treated before. If you have a specific gene type (RAS/BRAF wild-type) and are in generally good health, this study may be an option.
Chongqing, Chongqing MunicipalityAges 18–75 - NCT06285734Recruiting
Trial on small intestinal bacterial overgrowth in people with abdominal bloating
This study looks at whether certain bacteria in the small intestine cause abdominal bloating and distension. It aims to help understand this common problem and find better ways to treat it.
Jinan, ShandongAges 18–60 - NCT06192082Recruiting
Heart risks during painless stomach scope in frail elderly
This study looks at whether older, frail patients have heart problems during a painless stomach scope (gastroscopy). It aims to find safer ways to give sedation for these patients.
Beijing, Beijing MunicipalityAges 65–100 - NCT06195332Recruiting
Comparing two hernia repair methods (open vs. camera-assisted)
This study compares two ways to fix a hernia that appears after a previous belly surgery: one uses a larger cut (open surgery) and the other uses smaller cuts and a camera. The goal is to see which approach leads to a better recovery.
MoscowAges 18–90 - NCT06142084Recruiting
Digesting plant proteins: a study in people with ileostomy
This study looks at how well your body digests different plant-based proteins. You may help by providing samples through your ileostomy, so researchers can understand which proteins are easiest to absorb.
ÖrebroAges 18–75 - NCT06329102Recruiting
Right colon cancer surgery and specimen quality study
This trial is studying how the type and method of surgery for right-sided colon cancer affects the quality of the removed tissue. It aims to improve surgical techniques for this type of cancer.
BergenAges 18–99 - NCT06182215Recruiting
Brain function after major abdominal surgery in older adults
This trial studies whether older adults experience thinking or memory changes after major abdominal surgery. It aims to understand these changes so doctors can better support recovery.
Guangzhou, GuangdongAges 65–90 - NCT06256705Recruiting
Study of targeted radiation for neuroendocrine tumors
This study follows people with a type of digestive tract cancer called GEP-NET that has spread and is growing. It uses a special imaging scan to find tumors that absorb a radioactive drug, then treats them with targeted radiation therapy. The goal is to learn more about who benefits most from this treatment.
ClichyAges 18 years+ - NCT06298331Recruiting
Aerobic exercise with abdominal massage for chronic constipation
This study tests whether adding aerobic exercise to abdominal massage helps people with chronic constipation. If you have ongoing constipation and haven't tried new treatments recently, you may be eligible.
AnkaraAges 18–65 - NCT06322862Recruiting
Fluorescence test for blood flow in emergency bowel surgery
This trial tests if a special imaging technique (fluorescence) can help doctors see how well blood is flowing to the bowel during emergency surgery for suspected mesenteric ischemia. This could help them decide which part of the bowel to remove, if any.
Copenhagen, Capital RegionAges 18 years+
Common questions
- How many digestive system clinical trials are recruiting?
- Clin2 is tracking 7,874 recruiting gastroenterology studies from the U.S. registry right now, out of 12,294 we cover in this area in total.
- What does “Digestive system” cover here?
- Conditions of the stomach, intestines, liver, and the rest of the digestive tract. We group each study into digestive system based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a digestive system trial near me?
- Use the search to filter digestive system studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Mental health
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.