Gastroenterology
Digestive system clinical trials
Conditions of the stomach, intestines, liver, and the rest of the digestive tract. We’re tracking 7,916 recruiting studies in this area right now.
By phase
- Not applicable4,936
- Phase 21,188
- Phase 1583
- Phase 3465
- Phase 1/Phase 2396
- Phase 4237
- Phase 2/Phase 3111
Top conditions
- Colorectal Cancer493
- Gastric Cancer298
- Pancreatic Cancer292
- Hepatocellular Carcinoma284
- Esophageal Cancer191
- Rectal Cancer176
- Breast Cancer148
- Crohn Disease144
- Ulcerative Colitis140
- Colon Cancer115
- Inflammatory Bowel Diseases108
- Hepatocellular Carcinoma (HCC)107
- Liver Cancer101
- Lung Cancer99
- Pancreas Cancer94
- Esophageal Squamous Cell Carcinoma89
- Ovarian Cancer88
- Cystic Fibrosis78
Leading sponsors
- Fudan University104
- Sun Yat-sen University91
- Mayo Clinic75
- Chinese University of Hong Kong60
- M.D. Anderson Cancer Center58
- Second Affiliated Hospital, School of Medicine, Zhejiang University57
- Assistance Publique - Hôpitaux de Paris55
- Sixth Affiliated Hospital, Sun Yat-sen University50
- National Taiwan University Hospital49
- Cancer Institute and Hospital, Chinese Academy of Medical Sciences48
Where studies are running
- California461
- Arizona174
- Texas148
- Florida135
- Massachusetts127
- Alabama123
- New York123
- Maryland87
- Ohio80
- Pennsylvania72
Recruiting studies7,916 total
- NCT07510984Recruiting
Heterotopic gastric mucosa and quality of life study
This study looks at how a condition called heterotopic gastric mucosa (HGM), which is stomach tissue in the wrong place in the esophagus, affects symptoms and quality of life. If you are scheduled for an upper endoscopy and are at least 18, you may be able to join.
Bottrop, North Rhine-WestphaliaAges 18 years+ - NCT07511244Recruiting
Spinal cord stimulation for bladder and bowel control after spinal cord injury
This trial tests whether spinal cord stimulation can help improve bladder and bowel function in people who have had a spinal cord injury for more than 6 months. The goal is to see if this treatment can restore more control and quality of life.
BeijingAges 18–60 - NCT07512232Recruiting
Rectal Lavage During Surgery to Lower Cancer Recurrence Risk
This trial tests whether rinsing the rectum with special fluid during minimally invasive surgery for mid-to-low rectal cancer helps prevent the cancer from coming back locally. The procedure aims to wash away cancer cells that might have leaked into the surgical area.
Guangzhou, GuangdongAges 18–75 - NCT07512934Recruiting
Pancreatic Function Study in Early Type 2 Diabetes
This study examines how the pancreas works in people newly diagnosed with type 2 diabetes. Researchers will assess pancreatic function to better understand early diabetes and potentially improve treatment.
Aktobe, AktobeAges 18–74 - NCT07513038RecruitingPhase 1/Phase 2
Using dye imaging to diagnose bile duct blockage in infants
This trial tests whether a special fluorescent dye called indocyanine green (ICG) can help doctors better diagnose biliary atresia—a rare condition where a baby's bile ducts don't form properly. The dye is used during an imaging scan to light up the bile system so doctors can see it more clearly.
Boston, MassachusettsAges birth–3 months - NCT07514494RecruitingPhase 2
Intensive Ovarian Cancer Treatment Using Pressurized Chemotherapy
This trial tests a special chemotherapy delivery method called PIPAC (pressurized intraperitoneal aerosol chemotherapy) for ovarian cancer that has spread within the abdomen. The goal is to deliver cancer-fighting drugs more effectively directly to where the cancer is.
BalashikhaAges 18–75 - NCT07517029Recruiting
Gut Bacteria Study in Post-Infectious IBS
This study looks at how gut bacteria may change in people who developed irritable bowel syndrome (IBS) after a stomach infection. Researchers hope to understand why some people recover completely while others develop ongoing digestive problems.
RomeAges 18 years+ - NCT07517107RecruitingPhase 2
Blood tests to guide gastric cancer treatment decisions
This study uses special blood tests to detect cancer DNA and help doctors decide the best treatment plan for gastric cancer. The goal is to improve outcomes by personalizing therapy based on how your cancer responds.
ShanghaiAges 18 years+ - NCT07517198RecruitingPhase 1
EXS74539 Study for Advanced Solid Tumors
This is an early-stage study testing a new cancer drug called EXS74539 to find the right dose and see how well it works in people with various advanced solid tumors. The drug may help patients whose cancers have stopped responding to standard treatments.
Los Angeles, CaliforniaAges 18 years+ - NCT07517432Recruiting
Registry tracking robotic surgery outcomes in gastric cancer
This study follows patients with stomach cancer who have robotic-assisted surgery to understand how well this advanced surgical approach works. By collecting information from multiple hospitals worldwide, researchers can learn what outcomes patients experience and how to improve care.
Hong KongAges Any age - NCT07517926Recruiting
Chewing gum and cold water gargle after lung breathing tube procedure
This study tests whether chewing gum and gargling with cold water can reduce sore throat and other discomfort after a bronchoscopy—a procedure where doctors look inside your airways with a thin camera. If it works, it could be a simple, safe way to feel better after the procedure.
AnkaraAges 18 years+ - NCT07518147RecruitingPhase 3
BL-M05D1 for advanced stomach cancer after first treatment
This study tests a new antibody drug (BL-M05D1) for advanced stomach or lower esophagus cancer that did not respond to first-line chemotherapy. The drug targets a protein called claudin 18.2 found on some cancer cells and may help slow or shrink the cancer.
Beijing, Beijing MunicipalityAges 18–75 - NCT07518784Recruiting
Testing a new liver scanning device for fatty liver disease
This study tests a new device called LiverScope® that scans your liver to detect fatty liver disease (MASLD). The scan uses special imaging technology and may help doctors diagnose liver disease more quickly and accurately.
La Jolla, CaliforniaAges 18 years+ - NCT07519057Recruiting
Carbohydrate drink before liver transplant surgery
This study tests whether drinking a carbohydrate solution before planned liver transplant surgery helps patients recover better afterward. Researchers believe it may reduce complications and improve healing.
WarsawAges 18 years+ - NCT07519330RecruitingPhase 2
Testing HH-006 treatment for chronic hepatitis B
This study tests a new drug called HH-006 to see if it can help treat chronic hepatitis B infection. Participants will be grouped by their infection level, and the study checks whether the drug is safe and works to reduce the hepatitis B virus.
Chongqing, Chongqing MunicipalityAges 18–45 - NCT07519395RecruitingPhase 2
Camlipixant for abdominal symptoms in IBS-D and IBS-M
This study tests whether a new drug called camlipixant can reduce belly pain and other uncomfortable symptoms in people with irritable bowel syndrome that causes diarrhea or mixed symptoms. The trial compares camlipixant to a placebo (inactive pill) to see if it works better.
Anniston, AlabamaAges 18–80 - NCT07519486RecruitingPhase 2
Nutrition support during cancer treatment before surgery
This trial tests whether intensive nutritional support helps patients with advanced esophageal cancer (a type of squamous cell carcinoma) respond better to treatment before surgery. The goal is to improve how well the cancer shrinks and prepare the body for a successful operation.
Chengdu, SichuanAges 18–80 - NCT07519850Recruiting
How Perianal Disease Affects Sexual Health and Quality of Life
This study explores how chronic perianal conditions—like anal fistulas or pilonidal disease—affect patients' sexual function and relationships. Researchers will ask you to complete surveys about your symptoms and sexual health to better understand this impact and help future patients.
Thessaloniki, ThessalonikiAges 18 years+ - NCT07519915Recruiting
Understanding Nerve Stimulation for Bowel Problems in Children
This research study looks at using sacral neuromodulation—a treatment that uses mild electrical stimulation of nerves in the lower spine—to help children with bowel movement problems. Researchers want to understand how well this treatment works and what improvements matter most to patients and families.
ErlangenAges 3–18 - NCT07520552Recruiting
Comparing surgical techniques for chronic anal fissures
This study compares two surgical approaches to treat chronic anal fissures (painful tears in the anus) that haven't healed with conservative treatment. The goal is to determine which technique is safer and more effective.
Çanakkale, ÇanakkaleAges 18 years+ - NCT07521332RecruitingPhase 4
Testing Apixaban to Prevent Bleeding Complications in Cirrhosis
This study tests whether a blood thinner called apixaban can safely prevent dangerous bleeding in people with cirrhosis (liver scarring) who have portal hypertension (high blood pressure in veins leading to the liver). The goal is to see if it reduces bleeding risk without causing excessive bleeding.
Hyderābād, SindhAges 18 years+ - NCT07521969Recruiting
Outpatient care after emergency appendix removal surgery
This trial tests whether patients with a specific type of appendix infection (gangrenous appendicitis) can safely recover at home instead of staying in the hospital after surgery. The goal is to see if home-based care with close follow-up visits works as well as traditional hospital stays.
Seville, SevillaAges 14 years+ - NCT07522528Recruiting
Biologics and Nutrition Treatment for Active Crohn's in Young People
This study tests whether combining biologic medicines (TNF-alpha inhibitors like infliximab or adalimumab) with a special nutrition plan helps young people with active Crohn's disease feel better. The nutrition plan may include drinking special formula drinks instead of regular food (or alongside some regular food).
AberdeenAges 6–18 - NCT07522762Recruiting
Long-term life after advanced GIST on targeted drug therapy
This study follows people who have been taking targeted cancer drugs (called TKIs) for advanced GIST for at least 2 years to understand how these long-term treatments affect quality of life, side effects, and daily living. Researchers want to learn what challenges patients face and how to better support them.
Amsterdam, North HollandAges 18 years+
Common questions
- How many digestive system clinical trials are recruiting?
- Clin2 is tracking 7,916 recruiting gastroenterology studies from the U.S. registry right now, out of 12,516 we cover in this area in total.
- What does “Digestive system” cover here?
- Conditions of the stomach, intestines, liver, and the rest of the digestive tract. We group each study into digestive system based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a digestive system trial near me?
- Use the search to filter digestive system studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Mental health
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.