Otolaryngology
Ear, nose & throat clinical trials
Hearing, balance, and conditions of the ears, nose, sinuses, and throat. We’re tracking 1,366 recruiting studies in this area right now.
By phase
- Not applicable975
- Phase 2167
- Phase 398
- Phase 146
- Phase 434
- Phase 1/Phase 232
- Phase 2/Phase 314
Top conditions
- Nasopharyngeal Carcinoma80
- Dysphagia72
- Hearing Loss61
- Tinnitus31
- Hearing Loss, Sensorineural25
- Allergic Rhinitis23
- Nasopharyngeal Carcinoma (NPC)23
- Head and Neck Cancer22
- Oropharynx Cancer21
- Stroke19
- Sensorineural Hearing Loss18
- Nasopharyngeal Cancinoma (NPC)16
- Chronic Rhinosinusitis With Nasal Polyps15
- Oropharyngeal Cancer15
- Nasopharyngeal Cancer14
- Vestibular Schwannoma14
- Head and Neck Squamous Cell Carcinoma13
- Chronic Rhinosinusitis (CRS)12
Leading sponsors
- Sun Yat-sen University58
- Eye & ENT Hospital of Fudan University17
- Cairo University15
- Assistance Publique - Hôpitaux de Paris14
- NYU Langone Health14
- Mayo Clinic12
- National Cancer Institute (NCI)12
- Johns Hopkins University11
- Ming-Yuan Chen10
- Cochlear9
Where studies are running
- California62
- Maryland37
- New York35
- Florida29
- Massachusetts21
- Illinois20
- Arizona17
- Texas17
- Colorado16
- Alabama15
Recruiting studies1,366 total
- NCT06805175Recruiting
Balance implant study for adults with dizziness
This study tests a new device that may help restore balance for people with long-term dizziness from inner ear problems. The implant is placed surgically to stimulate the balance nerve.
Antwerp, WilrijkAges 18 years+ - NCT07107256RecruitingPhase 3
Study of TQC2731 for chronic sinusitis with nasal polyps
This trial tests an injectable drug called TQC2731 for people with chronic sinusitis and nasal polyps that haven't been controlled well enough by standard treatments like steroid sprays or surgery. The goal is to see if it helps reduce nasal congestion, improve sense of smell, and shrink polyps.
Fuyang, AnhuiAges 18–75 - NCT03751566Recruiting
Acupuncture to ease short-term side effects of head and neck radiation
This trial studies whether adding acupuncture to standard radiation care can reduce short-term side effects from radiation for head and neck tumors. You might qualify if you are having treatment with the goal of cure or after-surgery prevention and can reliably complete symptom/side-effect tracking.
BrnoAges 18 years+ - NCT07489742Recruiting
Ondansetron lozenge vs IV for shivering prevention in tonsillectomy
This trial tests whether an ondansetron lozenge works as well as IV ondansetron to prevent shivering after tonsillectomy in children. It could offer a needle-free way to reduce side effects during recovery.
Tanta, El-GharbiaAges 4–15 - NCT07060261Recruiting
Pre-op MRI for HPV+ tonsil cancer surgery
This trial is looking at whether an MRI before surgery can help improve outcomes for people with HPV-positive tonsil cancer who are undergoing robotic surgery (TORS). The results may help doctors better plan surgery to remove all cancer.
Cleveland, OhioAges 18 years+ - NCT07068048Enrolling by invitation
Steroid wash during thyroid surgery to protect voice nerves
This trial tests if rinsing the surgical area with a steroid drug (dexamethasone) during thyroid surgery can help prevent damage to the nerve that controls your vocal cords. It may lower the risk of voice changes after surgery.
Petaling Jaya, SelangorAges 18–80 - NCT07608861Recruiting
Numbing Block to Reduce Pain Medicine During Nose Surgery
This study tests whether a special numbing injection in the upper jaw (bilateral maxillary block) helps reduce the amount of pain medication needed during septorhinoplasty—a surgery to reshape the nose and straighten the septum. The goal is to find ways to use less strong pain medication during surgery.
Yenimahalle, AnkaraAges 18–65 - NCT07515885Recruiting
Electroacupuncture for Shingles Pain Relief
This study tests whether electroacupuncture (a form of acupuncture with mild electrical stimulation) can reduce pain from shingles (herpes zoster), a viral infection that causes painful skin rashes. Researchers will also measure certain markers in your blood to understand how the treatment works.
Hangzhou, ZhejiangAges 20–80 - NCT07379866Recruiting
Nerve blocks for pain relief after tonsil removal in children
This trial tests if injecting numbing medicine near certain nerves in the head and neck can reduce pain after tonsil and adenoid surgery in children aged 5–13. It may help them recover more comfortably.
Cairo, GovernorateAges 5–13 - NCT06677125Recruiting
Magnetic mallet and special drill for sinus lift in dental implants
This study tests two tools (a magnetic mallet and a special drill) used to lift the sinus floor during dental implant placement in the upper jaw. It may help people who need implants but have limited bone height.
AlexandriaAges 30–60 - NCT07524452RecruitingPhase 3
Becotatug vedotin plus immunotherapy for head and neck cancer
This trial tests a new combination of two drugs—becotatug vedotin (a targeted therapy) and a PD-1 inhibitor (an immunotherapy)—given before surgery to treat advanced head and neck squamous cell carcinoma. The goal is to shrink tumors and improve surgical outcomes for patients with specific cancer markers.
Zhuhai, GuangdongAges 18–75 - NCT06683560Recruiting
3D-printed aligners for cleft lip and palate repair
This study tests whether custom 3D-printed aligners can help shape a baby's cleft lip, gum, and palate before surgery. It aims to make traditional molding treatment more precise and easier for families.
Cairo, AbbasyaAges Up to 1 month - NCT07612995Recruiting
3D Printing Models to Help Students Practice Breathing Tube Placement
This study tests whether using 3D-printed models of airways helps medical students learn to place breathing tubes (endotracheal intubation) more successfully. Researchers will compare traditional training methods with this new 3D printing technology.
Taiyuan, ShaanxiAges Any age - NCT07371234RecruitingPhase 2
Low-dose radiation and immunotherapy before surgery for head and neck cancer
This trial tests a combination of low-dose radiation and an immunotherapy drug (similar to Keytruda) given before surgery for advanced head and neck cancer. The goal is to see if this approach can shrink tumors and improve outcomes.
GuangdongAges 18–75 - NCT05315791Recruiting
Bone-window dental procedure for missing back upper tooth
This study looks at how to place bone support for an upper back tooth replacement when part of the upper jaw bone is limited. If you’re missing one upper back tooth for at least 3 months, they may use a specific “bone window” approach guided by a 3D scan.
Hangzhou, ZhejiangAges 18–80 - NCT06282497Recruiting
New radiation technique to reduce dry mouth in nasopharyngeal cancer
This trial compares a new radiation technique designed to reduce dry mouth (xerostomia) with standard radiation for people with nasopharyngeal cancer. It aims to see if the new approach can protect saliva glands while still treating the cancer effectively.
Zhongshan, GuangdongAges 18–70 - NCT05062005RecruitingPhase 3
Tests two ways of treating locally advanced nasopharyngeal cancer
This phase 3 trial compares a standard treatment plan (CRT) versus a new approach (ICCRT) for people with locally advanced nasopharyngeal cancer, without spread to distant organs. It aims to see which plan works better and is safe for tumors in the head and neck area.
Guangzhou, GuangdongAges 18–65 - NCT07216937Recruiting
Comparing 3D-printed vs. regular ear tip comfort
This study compares how comfortable 3D-printed ear tips are versus regular ear tips for people with normal hearing.
Tucson, ArizonaAges 18–89 - NCT07537699RecruitingPhase 2
Ear Stimulation and Steroid for Chemo-Related Nausea
This trial tests whether stimulating specific points on your ear, combined with a steroid medication, can reduce nausea and vomiting caused by chemotherapy drugs (docetaxel and cyclophosphamide) given after breast cancer surgery. Many patients experience these side effects, and the study wants to see if this non-drug approach helps.
HangzhouAges 18–85 - NCT05997186Recruiting
Reinnervated flap for mouth and throat reconstruction
This trial tests a new way to rebuild parts of the mouth or throat after surgery, using a flap from the thigh that is reconnected to nerves to help it work better. It may help people who need a reconstructive procedure for these areas.
BaselAges 18 years+ - NCT07546045Recruiting
Robotic Surgery and Swallowing Recovery for Head and Neck Cancer
This trial tests a specialized robotic surgical approach for head and neck cancers, combined with personalized speech and swallowing rehabilitation. The goal is to remove tumors while preserving organ function and improving your ability to swallow and speak after surgery.
LausanneAges 18 years+ - NCT07193485Recruiting
Buteyko breathing for seniors with chronic ear tube blockage
This study tests whether a special breathing technique (Buteyko breathing) can help seniors with long-lasting Eustachian tube dysfunction that affects only one ear. It may offer a drug-free way to relieve ear pressure or discomfort.
Dokki, Giza GovernorateAges 65–75 - NCT07565740RecruitingPhase 1
Vaccine plus immunotherapy for newly diagnosed HPV-positive throat cancer
This trial tests a new nasal vaccine combined with an immunotherapy drug (tislelizumab) given before surgery for people with HPV-positive oropharyngeal cancer. The goal is to help the immune system fight the cancer and potentially improve outcomes after surgery.
Chengdu, SichuanAges 18 years+ - NCT05860868RecruitingPhase 3
Two versus three chemo treatments before radiation for nasopharyngeal cancer
This Phase 3 trial compares giving two cycles versus three cycles of chemotherapy before other treatment for locally advanced nasopharyngeal cancer. It may help find which schedule works best to control the cancer while managing side effects.
Guangzhou, Other (Non U.s.)Ages 18–65
Common questions
- How many ear, nose & throat clinical trials are recruiting?
- Clin2 is tracking 1,366 recruiting otolaryngology studies from the U.S. registry right now, out of 2,207 we cover in this area in total.
- What does “Ear, nose & throat” cover here?
- Hearing, balance, and conditions of the ears, nose, sinuses, and throat. We group each study into ear, nose & throat based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a ear, nose & throat trial near me?
- Use the search to filter ear, nose & throat studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Mental health
- Digestive system
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.