Otolaryngology
Ear, nose & throat clinical trials
Hearing, balance, and conditions of the ears, nose, sinuses, and throat. We’re tracking 1,269 recruiting studies in this area right now.
By phase
- Not applicable890
- Phase 2154
- Phase 3103
- Phase 147
- Phase 431
- Phase 1/Phase 230
- Phase 2/Phase 314
Top conditions
- Nasopharyngeal Carcinoma73
- Dysphagia66
- Hearing Loss61
- Tinnitus29
- Hearing Loss, Sensorineural24
- Nasopharyngeal Carcinoma (NPC)24
- Head and Neck Cancer23
- Allergic Rhinitis22
- Oropharynx Cancer21
- Nasopharyngeal Cancinoma (NPC)18
- Sensorineural Hearing Loss18
- Stroke17
- Oropharyngeal Cancer14
- Vestibular Schwannoma14
- Chronic Rhinosinusitis With Nasal Polyps13
- Deafness13
- Head and Neck Squamous Cell Carcinoma13
- Nasopharyngeal Cancer13
Leading sponsors
- Sun Yat-sen University57
- Assistance Publique - Hôpitaux de Paris14
- Eye & ENT Hospital of Fudan University14
- National Cancer Institute (NCI)14
- Cairo University13
- NYU Langone Health13
- Mayo Clinic12
- Johns Hopkins University11
- Ming-Yuan Chen11
- Massachusetts Eye and Ear Infirmary10
Where studies are running
- California61
- Maryland38
- Florida32
- New York32
- Massachusetts24
- Illinois20
- Texas20
- Alabama15
- Arizona15
- Colorado15
Recruiting studies1,269 total
- NCT07683689Recruiting
Better hearing with cochlear implants
This study looks at how the inner ear's health affects cochlear implant results. Researchers hope to use special programming to improve hearing for people with Advanced Bionics implants.
Boston, MassachusettsAges 18–80 - NCT06643702Recruiting
Dizziness and balance in older adults
This study is looking at whether dizziness and balance problems in older adults are caused by BPPV (tiny crystals in the inner ear). If you qualify, you may be diagnosed with simple head movements.
Saltsjö-Boo, Stockholm CountyAges 65 years+ - NCT06662929Recruiting
Arabic quality of life measure for head and neck cancer patients
This study will test a new Arabic questionnaire to measure how radiotherapy affects the quality of life of head and neck cancer patients. If you are receiving, have received, or will receive radiation treatment for head or neck cancer, you may be able to help by filling out surveys.
RiyadhAges 18 years+ - NCT04671381Recruiting
More affordable adult hearing care for eligible Alabama residents
This study aims to improve access and affordability of hearing healthcare for adults who have mild to moderate hearing loss. If you live in parts of South or West Central Alabama and meet the age and health requirements, your care may be coordinated through the program being tested.
Tuscaloosa, AlabamaAges 40 years+ - NCT07678086Recruiting
Breathing tube pressure and sore throat in children's appendix surgery
This trial tests whether carefully managing the pressure in the breathing tube during surgery can help prevent a sore throat in children after they have their appendix removed by keyhole surgery. It may help your child have a more comfortable recovery.
Ankara, YenimahalleAges 6–18 - NCT07678931RecruitingPhase 3
New injection for seasonal allergies in teens
This trial tests a new biologic medicine (injection) to see if it can better control seasonal allergy symptoms in teens who haven't had good relief from standard treatments like nasal sprays.
Beijing, Beijing MunicipalityAges 12–18 - NCT06664697Recruiting
Study of the IotaSOFT Insertion System for cochlear implants
This trial tests a new robotic system that helps doctors insert cochlear implant electrodes more gently. It may lead to safer surgery and better hearing outcomes for people with severe hearing loss.
Indianapolis, IndianaAges 12 years+ - NCT07672418Recruiting
Pain relief after tonsil surgery: ibuprofen vs. ketorolac
This study compares two common pain relievers (ketorolac and ibuprofen) given after tonsil/adenoid surgery in teenagers. It aims to see which works better while keeping side effects low.
Houston, TexasAges 13–18 - NCT06439927Recruiting
New method for closing a hole in the nasal septum
This trial is testing a new way to close a hole in the nasal septum (the wall inside your nose) during surgery. It may be a better option for people who need this repair.
CairoAges 18–58 - NCT06675214RecruitingPhase 3
Immunotherapy with modified radiation for advanced NPC
This trial tests a new way to give radiation therapy after immunotherapy and chemotherapy for people with advanced nasopharyngeal cancer (NPC) that has partially shrunk. It aims to see if a different radiation schedule works better and has fewer side effects.
Zhuhai, GuangdongAges 18–65 - NCT06677125Recruiting
Magnetic mallet and special drill for sinus lift in dental implants
This study tests two tools (a magnetic mallet and a special drill) used to lift the sinus floor during dental implant placement in the upper jaw. It may help people who need implants but have limited bone height.
AlexandriaAges 30–60 - NCT07663409Recruiting
Studying markers in sinusitis patients having surgery
This study looks at tissue and blood samples from people with chronic sinusitis to find markers that could predict how the disease behaves. It may help doctors choose better treatments in the future.
AlexandroupoliAges 18 years+ - NCT07661771RecruitingPhase 3
Personalized radiation therapy for nasopharyngeal cancer
This trial tests a new way to plan radiation treatment for nasopharyngeal cancer, where the target area is tailored to each patient's tumor spread. It aims to improve effectiveness while reducing side effects.
Dongguan, GuangdongAges 18–65 - NCT05882903RecruitingPhase 2
Nasal steroid cream after sinus surgery for chronic sinus trouble
This trial studies whether placing a steroid nasal cream inside your sinus area can reduce symptoms in people with chronic rhinosinusitis (CRS) even after sinus surgery. It may help lower ongoing inflammation and symptoms for those who still feel unwell despite usual medical treatments.
Sydney, New South WalesAges 18–80 - NCT06683261Recruiting
Real-world study of biologics for nasal polyps
This study follows people with chronic rhinosinusitis and nasal polyps who are starting a biologic medication (omalizumab, mepolizumab, or dupilumab) to see how well it works in real life.
AalstAges 18 years+ - NCT06260618Recruiting
Testing a new gel for better healing in ear surgery
This trial tests a special gel applied during common ear surgeries to see if it helps healing and improves hearing. It may be an option for people having surgery to fix a perforated eardrum, repair ear bones, or treat chronic ear infections.
Adelaide, South AustraliaAges 18 years+ - NCT07651891RecruitingPhase 4
Dog allergy vaccine study for Swedish adults
This study tests an allergy shot (Alutard SQ Dog) for people with moderate to severe dog allergies. It aims to see how well the vaccine works in Swedish medical practices.
Lund, Skåne CountyAges 18–50 - NCT06688760Recruiting
Surgery vs surgery plus lower-dose radiation for early nasopharyngeal cancer
This trial compares two treatments for newly diagnosed Stage I nasopharyngeal cancer: surgery alone versus surgery followed by a lower dose of radiation. The goal is to see if adding a gentler radiation dose can prevent the cancer from coming back without too many side effects.
Guangzhou, GuangdongAges 18–70 - NCT07640568Recruiting
Parent-Led Ear Infection Detection Using Phone Imaging
This study teaches parents how to use a special phone camera tool to spot ear infections (acute otitis media, or AOM) at home. Researchers want to see if parents can reliably identify these infections early, which might help avoid unnecessary doctor visits or catch problems sooner.
Vaasa, PohjanmaaAges 1 year–3.9 years - NCT07638579Enrolling by invitation
Nerve monitoring methods during thyroid and parathyroid surgery
This study compares two ways to monitor nerves during thyroid or parathyroid surgery to see which method works better. During surgery, doctors use electrical sensors to make sure they don't accidentally damage important nerves in your neck.
ThessalonikiAges Any age - NCT07646119Recruiting
Understanding Hidden Hearing Loss in Older Adults
This study investigates 'hidden hearing loss'—a condition where people have normal standard hearing test results but still struggle to hear in difficult situations. Researchers want to understand this problem better in adults over 60 to potentially improve diagnosis and treatment.
Shanghai, Shanghai MunicipalityAges 60 years+ - NCT07633158Recruiting
Real-world study of tezepelumab for chronic nasal polyps
This study follows patients with chronic rhinosinusitis with nasal polyps (CRSwNP)—a condition causing blocked sinuses and nasal growths—who are starting a new biologic medication called tezepelumab. Researchers will track how symptoms and quality of life improve over time in everyday medical practice.
BochumAges 18–130 - NCT07637981RecruitingPhase 2
Safety Study of DX243 for Hearing Loss in Noise
This study tests a new medicine (DX243) to see if it is safe and well-tolerated in people with hearing difficulties, especially trouble hearing speech in noisy environments. The goal is to understand how the body processes this medicine and whether it might help improve hearing.
Liège, LiègeAges 18–75 - NCT07635719Recruiting
Comparing surgical tools for tonsil and adenoid removal
This study compares different surgical tools used during tonsil and adenoid removal surgery in children. The goal is to see which tool works best and is safest for this common pediatric surgery.
The Bronx, New YorkAges 1–18
Common questions
- How many ear, nose & throat clinical trials are recruiting?
- Clin2 is tracking 1,269 recruiting otolaryngology studies from the U.S. registry right now, out of 2,074 we cover in this area in total.
- What does “Ear, nose & throat” cover here?
- Hearing, balance, and conditions of the ears, nose, sinuses, and throat. We group each study into ear, nose & throat based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a ear, nose & throat trial near me?
- Use the search to filter ear, nose & throat studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Mental health
- Digestive system
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.