Otolaryngology
Ear, nose & throat clinical trials
Hearing, balance, and conditions of the ears, nose, sinuses, and throat. We’re tracking 1,269 recruiting studies in this area right now.
By phase
- Not applicable890
- Phase 2154
- Phase 3103
- Phase 147
- Phase 431
- Phase 1/Phase 230
- Phase 2/Phase 314
Top conditions
- Nasopharyngeal Carcinoma73
- Dysphagia66
- Hearing Loss61
- Tinnitus29
- Hearing Loss, Sensorineural24
- Nasopharyngeal Carcinoma (NPC)24
- Head and Neck Cancer23
- Allergic Rhinitis22
- Oropharynx Cancer21
- Nasopharyngeal Cancinoma (NPC)18
- Sensorineural Hearing Loss18
- Stroke17
- Oropharyngeal Cancer14
- Vestibular Schwannoma14
- Chronic Rhinosinusitis With Nasal Polyps13
- Deafness13
- Head and Neck Squamous Cell Carcinoma13
- Nasopharyngeal Cancer13
Leading sponsors
- Sun Yat-sen University57
- Assistance Publique - Hôpitaux de Paris14
- Eye & ENT Hospital of Fudan University14
- National Cancer Institute (NCI)14
- Cairo University13
- NYU Langone Health13
- Mayo Clinic12
- Johns Hopkins University11
- Ming-Yuan Chen11
- Massachusetts Eye and Ear Infirmary10
Where studies are running
- California61
- Maryland38
- Florida32
- New York32
- Massachusetts24
- Illinois20
- Texas20
- Alabama15
- Arizona15
- Colorado15
Recruiting studies1,269 total
- NCT07718620Recruiting
HPV-related throat cancer radiation trial
This trial tests whether radiation or chemoradiation works well for HPV-positive throat cancer. It may be an option if you have this type of cancer and are getting or have already had surgery.
Brno, Czech RepublicAges 18 years+ - NCT05849844Recruiting
Study for children and adults with a persistent ear tube or small hole
This study looks at Tympanoseal for people who still have a childhood ear tube or a small eardrum hole. It may help protect the ear and improve healing, while researchers compare outcomes using a standardized approach.
Farmington Hills, MichiganAges 2–100 - NCT07711262RecruitingPhase 3
Study of Rupatifen for seasonal allergic rhinitis
This trial tests an experimental capsule called Rupatifen for adults with seasonal allergies. It aims to see if it reduces symptoms like sneezing, runny nose, and congestion during spring or fall allergy seasons.
Baoding, HebeiAges 18–65 - NCT07710196RecruitingPhase 3
NPI-001 for preserving vision in usher syndrome
This study tests a 24-month treatment with NPI-001, an oral medication, to see if it can slow the loss of light-sensing cells in the retina for people with retinitis pigmentosa tied to Usher syndrome. It aims to preserve remaining vision and delay further damage.
Dallas, TexasAges 18 years+ - NCT07714525RecruitingPhase 2
Steroid nanocapsules after nasal surgery
This trial tests whether a new form of steroid (triamcinolone) delivered in tiny capsules can improve healing after common nasal surgeries for chronic sinusitis or nasal polyps.
Minya, Menia GovernorateAges 18–60 - NCT07708467Enrolling by invitation
Esophageal function study in eosinophilic esophagitis
This study looks at how the esophagus stretches and moves in people with eosinophilic esophagitis (EoE) who still have symptoms even though their inflammation is under control. The goal is to better understand why symptoms persist and find better ways to measure them.
Milan, MIAges 18 years+ - NCT07709143Recruiting
MRI study of balance disorders in older adults
This study uses MRI scans to look at the brain and inner ear in people with balance problems called bilateral vestibulopathy and presbyvestibulopathy. It aims to understand risk factors and improve diagnosis.
Shanghai, Shanghai MunicipalityAges 16 years+ - NCT07711639Recruiting
Tinnitus treatment with nerve stimulation
This trial tests a non-invasive treatment that stimulates a nerve in your ear or foot (called taVNS) to see if it helps reduce tinnitus. It is for people whose main problem is tinnitus and who have normal hearing in both ears.
Hualien CityAges 18–75 - NCT07706985RecruitingPhase 3
Immunotherapy for advanced nasopharyngeal cancer
This trial tests a new combination of chemotherapy and immunotherapy drugs for advanced nasopharyngeal cancer that has not spread to distant parts of the body. The goal is to see if this approach works better than standard treatment.
Guangzhou, GuangdongAges 18–70 - NCT07701967RecruitingPhase 4
Depemokimab for chronic sinusitis with nasal polyps
This trial tests a new antibody medicine (depemokimab) for Japanese adults with chronic sinusitis and nasal polyps. It aims to see if the drug alone can reduce symptoms without needing steroid nasal sprays.
EhimeAges 18 years+ - NCT07705243RecruitingPhase 3
Maintenance therapy for advanced nasopharyngeal cancer
This trial tests a combination of two drugs (becotatug vedotin and an anti-PD1 immunotherapy) as maintenance treatment after initial chemotherapy for advanced nasopharyngeal cancer that has spread or returned. It's for people whose disease has not progressed after standard first-line treatment.
Guangzhou, GuangdongAges 18–75 - NCT07703800Recruiting
Testing a better sound fitting for single-sided deaf cochlear implant users
This study tests if a cochlear implant fitting based on your ear's anatomy helps you hear speech in noisy places and enjoy music more. It is for people who are deaf in one ear and use a MED-EL cochlear implant.
AntwerpAges 18 years+ - NCT07702149Recruiting
Diet for Behcet's disease patients with ringing in the ears
This trial tests whether a special diet can help ringing in the ears (tinnitus) in people with Behcet's disease who also have obesity. The goal is to see if dietary changes reduce tinnitus symptoms.
Giza, DokkiAges 40–55 - NCT06061848RecruitingPhase 2/Phase 3
Grass pollen allergy shot with vitamin D
This study tests if adding vitamin D to a new type of allergy shot (ILIT) works better than standard allergy drops for grass pollen allergy. It may help if you have moderate to severe seasonal allergy symptoms.
LundAges 18–60 - NCT07688772RecruitingPhase 3
Study of SHR-1819 Injection for Seasonal Allergic Rhinitis
This trial tests a new injection called SHR-1819 for people with seasonal allergies who haven't responded well to standard treatments like nasal sprays or antihistamines. It aims to see if it can reduce allergy symptoms.
Beijing, Beijing MunicipalityAges 18–75 - NCT07690995Recruiting
Testing a new software to guide cochlear implant surgery
This trial tests a new software called OTOGUIDE that helps doctors monitor the insertion of a cochlear implant electrode during surgery. It may help make the procedure more precise and safer for patients.
Innsbruck, TyrolAges 18 years+ - NCT07691853Recruiting
Custom hearing fitting for cochlear implant users with a hearing aid in the other ear
This study tests a new way to adjust the settings on your cochlear implant and hearing aid together. The goal is to improve your hearing by using the natural structure of your ear, which might help you hear better in everyday situations.
AntwerpAges 18 years+ - NCT07692243Recruiting
Study of nose and sinus tissue differences
This study looks at tissue samples taken during nose or sinus surgery to better understand how these tissues vary. It may help researchers learn more about conditions affecting the nose and sinuses.
Guangzhou, GuangdongAges Any age - NCT07690670Recruiting
WhatsApp AI support vs paper support for new hearing aid users
This study tests whether using WhatsApp for support (with help from AI) is better than paper materials for people who are using hearing aids for the first time. It's for adults with mild to moderate hearing loss in both ears who can use WhatsApp.
Pretoria, ProvinceAges 18 years+ - NCT07690618RecruitingPhase 1
Heat therapy for head and neck cancer
This phase 1 trial tests adding heat therapy (thermotherapy) to standard radiation (with or without chemo) for head and neck cancer. It aims to see if it is safe and effective for patients with locally advanced disease who have not had radiation before.
Rotterdam, South HollandAges 18 years+ - NCT07690787RecruitingPhase 2
Study of JS207 for nasopharyngeal cancer
This trial tests a new drug, JS207, which targets two proteins (PD-1 and VEGF) that help cancer grow. It's for people with nasopharyngeal cancer that has not spread too much, and who have not had certain prior treatments.
Hong KongAges 18 years+ - NCT07697404RecruitingPhase 4
Finding the best dose of ciprofol for children's breathing mask
This study tests a new sedative medicine (ciprofol) to find the best dose for placing a breathing tube mask in children during surgery. It may help your child get a safer, more comfortable experience.
Wuhan, HubeiAges 1–12 - NCT07683689Recruiting
Better hearing with cochlear implants
This study looks at how the inner ear's health affects cochlear implant results. Researchers hope to use special programming to improve hearing for people with Advanced Bionics implants.
Boston, MassachusettsAges 18–80 - NCT07686211RecruitingEarly Phase 1
Study on better surgical guidance for head and neck cancer re-resection
This study tests a new augmented reality tool to help surgeons remove leftover tumor tissue after the first surgery. It might make re-resection more precise and improve cancer clearance.
Nashville, TennesseeAges Any age
Common questions
- How many ear, nose & throat clinical trials are recruiting?
- Clin2 is tracking 1,269 recruiting otolaryngology studies from the U.S. registry right now, out of 2,074 we cover in this area in total.
- What does “Ear, nose & throat” cover here?
- Hearing, balance, and conditions of the ears, nose, sinuses, and throat. We group each study into ear, nose & throat based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a ear, nose & throat trial near me?
- Use the search to filter ear, nose & throat studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Mental health
- Digestive system
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.