Otolaryngology
Ear, nose & throat clinical trials
Hearing, balance, and conditions of the ears, nose, sinuses, and throat. We’re tracking 1,266 recruiting studies in this area right now.
By phase
- Not applicable888
- Phase 2153
- Phase 3103
- Phase 147
- Phase 431
- Phase 1/Phase 230
- Phase 2/Phase 314
Top conditions
- Nasopharyngeal Carcinoma73
- Dysphagia66
- Hearing Loss61
- Tinnitus29
- Hearing Loss, Sensorineural24
- Nasopharyngeal Carcinoma (NPC)24
- Head and Neck Cancer23
- Allergic Rhinitis22
- Oropharynx Cancer21
- Nasopharyngeal Cancinoma (NPC)18
- Sensorineural Hearing Loss18
- Stroke17
- Oropharyngeal Cancer14
- Vestibular Schwannoma14
- Chronic Rhinosinusitis With Nasal Polyps13
- Deafness13
- Head and Neck Squamous Cell Carcinoma13
- Nasopharyngeal Cancer13
Leading sponsors
- Sun Yat-sen University57
- Assistance Publique - Hôpitaux de Paris14
- Eye & ENT Hospital of Fudan University14
- Cairo University13
- NYU Langone Health13
- National Cancer Institute (NCI)13
- Mayo Clinic12
- Johns Hopkins University11
- Ming-Yuan Chen11
- Massachusetts Eye and Ear Infirmary10
Where studies are running
- California61
- Maryland37
- Florida32
- New York32
- Massachusetts24
- Illinois20
- Texas20
- Alabama15
- Arizona15
- Colorado15
Recruiting studies1,266 total
- NCT05375266Recruiting
Study of immune signals in head and neck cancer
This study looks at “immune signals” in blood, saliva, and stool to learn more about head and neck cancers (especially squamous cell carcinoma). It may help researchers find patterns that improve understanding of disease or how treatment should be guided.
Erlangen, BavariaAges 18 years+ - NCT05877872RecruitingPhase 3
Smaller surgery after chemotherapy for recurring nasopharyngeal cancer
This trial tests whether doing a smaller surgery (after chemotherapy works well) can control recurring nasopharyngeal cancer while reducing treatment burden. It is for people whose cancer can be removed by surgery and who respond to an initial course of chemotherapy plus immunotherapy (or another targeted regimen).
Guangzhou, GuangdongAges 18–75 - NCT05453019Recruiting
Cochlear implants and changes in tinnitus symptoms
This study looks at whether a cochlear implant affects tinnitus (ringing in the ears) and related symptoms. It compares people who had tinnitus before surgery with people who did not.
Beijing, FranceAges 16–90 - NCT03919552RecruitingPhase 3
Chemoradiation with two cisplatin or carboplatin plans for nasopharyngeal cancer
This Phase 3 trial compares two chemotherapy-and-radiation combinations (cisplatin-based vs carboplatin-based) for locally advanced nasopharyngeal cancer that has not spread to distant organs. It may help researchers find which plan works best while balancing safety and effectiveness.
Guangzhou, GuangdongAges 18–64 - NCT05955859Recruiting
Testing how to diagnose fungal sinus infections
This study looks at better ways to diagnose a fungal (mycotic) infection in the sinus/near-nose area. You may be considered if you have symptoms on only one side, such as blockage or drainage, and you can safely take part in the study tests.
Ostrava, Czech RepublicAges 18–80 - NCT05994170Recruiting
Lower radiation dose to tumor area for early nasopharyngeal cancer
This trial studies whether lowering the radiation dose to a smaller area around the tumor is safe and effective for people with newly diagnosed nasopharyngeal cancer that has not spread. It may reduce side effects while still curing the cancer.
Zhongshan, GuangdongAges 18–70 - NCT01885767Recruiting
Neurofibromatosis registry for NF1, NF2, and Schwannomatosis
This trial is a patient registry portal for people diagnosed with neurofibromatosis types NF1, NF2, or schwannomatosis. By joining, you help researchers collect real-world information that may guide future studies and care.
New York, New YorkAges Any age - NCT06000527Recruiting
A French study on juvenile recurrent respiratory papillomatosis
This study is creating a national group of patients with juvenile recurrent respiratory papillomatosis, a condition causing wart-like growths in the airway. It aims to learn more about the disease and improve care.
ParisAges Any age - NCT05281952Recruiting
Tested ways to treat severe nosebleeds after failed packing
This study looks at different management strategies for severe nosebleeds when the initial packing method has not worked for over 48 hours. It also measures the cost/benefit of these approaches to help improve care.
ToulouseAges 18 years+ - NCT04463316Recruiting
Clinic study for people with rare genetic conditions
This study is for people who have a rare syndrome or rare congenital condition and are seen at a rare-disease clinic. It aims to better understand these conditions and how care works in a team setting, which may help guide future treatment decisions.
Rotterdam, South HollandAges 18 years+ - NCT06026878RecruitingPhase 3
GNT induction treatment for advanced nasopharyngeal cancer
This trial tests a new drug combination called GNT given before standard chemoradiation for people with locally advanced nasopharyngeal cancer. It aims to improve treatment outcomes.
Xi'an, ShaanxiAges 18–75 - NCT06039631RecruitingPhase 2
Immuno-chemo before surgery and organ-sparing treatment for throat cancer
This trial tests whether adding immunotherapy before surgery, followed by either radiation or organ-preserving surgery, can improve outcomes for people with locally advanced laryngeal or hypopharyngeal cancer. It may help avoid complete removal of the voice box.
Shanghai, Shanghai MunicipalityAges 18–75 - NCT05918510Recruiting
Blood and tumor study for virus markers in throat cancer
This study looks at virus-related markers and tiny gene regulators (microRNAs) in tumor tissue from people with certain throat cancers caused by human papilloma virus (HPV). It’s observational, meaning it does not change your treatment, but results may help doctors better understand these cancers and how they behave.
RomeAges 18 years+ - NCT06100601Recruiting
Nervous System and Voice Disorder Study
This study looks at how the autonomic nervous system (the part that controls things like heart rate and sweat) might be linked to functional dysphonia, a voice problem with no clear physical cause. If you have this voice disorder and meet the health and lifestyle criteria, your participation could help improve understanding of the condition.
Ghent, East-FlandersAges 18–60 - NCT06123221Recruiting
Sinus lift study: comparing two dental implant techniques
This study compares two methods for lifting the sinus floor to place dental implants. It is for people who need an implant in the upper jaw but don't have enough bone height. The goal is to see which technique works better.
Porto Alegre, Rio Grande do SulAges 18 years+ - NCT04685746Recruiting
Testing how balance and motion affect child development
This study looks at how the vestibular system (your balance and motion sensing) is involved in children’s thinking and movement. It compares typically developing children with children who have balance-related (vestibular) problems or certain neurodevelopmental conditions to understand what to expect and how development may differ.
GhentAges 6–13 - NCT03240965Recruiting
Testing changes in smell and taste after recent stroke
This study looks at how smell and taste may change after a new stroke, especially in the first few days. It may help doctors better understand and monitor symptoms related to eating and swallowing after stroke.
Giessen, HesseAges 18 years+ - NCT05851508RecruitingPhase 3
Steroid ear injections for vertigo in one-ear Ménière’s
This Phase 3 study compares injections of steroid medicine into the ear versus a dummy (placebo) injection to see if it reduces vertigo attacks in people with Ménière’s disease. It may help by improving balance symptoms and reducing how often attacks happen.
Leiden, South HollandAges 18–100 - NCT06161779Recruiting
Reconstructing the hypopharynx after cancer removal
This trial tests a surgical technique using a flap from under your chin to rebuild the hypopharynx after removing cancer. It may help people with hypopharyngeal cancer that has not spread far and who have not had radiation before.
Guangzhou, GuangdongAges 18–80 - NCT06167109Recruiting
NBI and MRI to guide radiation planning for one-sided nose cancer
This trial tests whether combining a special scope (NBI) with MRI scans can help doctors better target radiation therapy for a specific type of nose/throat cancer that affects only one side. It aims to make treatment more precise and reduce side effects.
Chongqing, Chongqing MunicipalityAges 18 years+ - NCT06001047Recruiting
Head acupuncture for BPPV residual symptoms
This study tests whether head acupuncture can help with lingering symptoms (like unsteadiness or discomfort) that sometimes remain after a successful repositioning procedure for BPPV, a common cause of vertigo. If you feel better but not fully steady, this treatment might help.
Xi'anAges 18–65 - NCT06092957RecruitingPhase 3
Reduced radiation after chemo-immunotherapy for high-risk nasopharyngeal cancer
This trial tests whether a lower dose of radiation, with or without additional chemo-immunotherapy, works as well as the standard full-dose chemoradiation for people with advanced nasopharyngeal cancer who had a complete response after initial chemo-immunotherapy.
Guangzhou, GuangdongAges 18–70 - NCT07860580Recruiting
Blood markers in children with congenital hearing loss
This study looks at certain substances in the blood of children with congenital hearing loss (hearing loss present from birth) to see if they are different from children with normal hearing. It may help doctors understand why hearing loss happens and could lead to better treatments.
SanliurfaAges Up to 17 years - NCT05670158Recruiting
Testing blood immune markers after cochlear implantation
This study compares blood and fluid-related immune “profiles” after cochlear implant surgery versus another ear/middle-ear surgery group. It aims to learn which immune signals may be linked to hearing outcomes and recovery after implantation.
MontpellierAges 18 years+
Common questions
- How many ear, nose & throat clinical trials are recruiting?
- Clin2 is tracking 1,266 recruiting otolaryngology studies from the U.S. registry right now, out of 2,063 we cover in this area in total.
- What does “Ear, nose & throat” cover here?
- Hearing, balance, and conditions of the ears, nose, sinuses, and throat. We group each study into ear, nose & throat based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a ear, nose & throat trial near me?
- Use the search to filter ear, nose & throat studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Mental health
- Digestive system
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.