Otolaryngology
Ear, nose & throat clinical trials
Hearing, balance, and conditions of the ears, nose, sinuses, and throat. We’re tracking 1,367 recruiting studies in this area right now.
By phase
- Not applicable975
- Phase 2168
- Phase 398
- Phase 146
- Phase 434
- Phase 1/Phase 232
- Phase 2/Phase 314
Top conditions
- Nasopharyngeal Carcinoma80
- Dysphagia71
- Hearing Loss61
- Tinnitus31
- Hearing Loss, Sensorineural25
- Allergic Rhinitis23
- Nasopharyngeal Carcinoma (NPC)23
- Head and Neck Cancer22
- Oropharynx Cancer21
- Sensorineural Hearing Loss18
- Stroke18
- Nasopharyngeal Cancinoma (NPC)16
- Chronic Rhinosinusitis With Nasal Polyps15
- Oropharyngeal Cancer15
- Nasopharyngeal Cancer14
- Vestibular Schwannoma14
- Head and Neck Squamous Cell Carcinoma13
- Chronic Rhinosinusitis (CRS)12
Leading sponsors
- Sun Yat-sen University58
- Eye & ENT Hospital of Fudan University17
- Cairo University15
- Assistance Publique - Hôpitaux de Paris14
- NYU Langone Health14
- Mayo Clinic12
- National Cancer Institute (NCI)12
- Johns Hopkins University11
- Ming-Yuan Chen10
- Cochlear9
Where studies are running
- California63
- Maryland37
- New York35
- Florida29
- Massachusetts21
- Illinois20
- Arizona17
- Texas17
- Colorado16
- Alabama15
Recruiting studies1,367 total
- NCT05670496Recruiting
NIDCD medical data and sample collection for communication disorders
This study collects medical information and specimens to support research on problems with hearing, balance, taste, smell, voice, speech, and language. It may help you (or your child) get additional evaluation and follow-up through NIDCD, especially if your clinician thinks it could be useful.
Bethesda, MarylandAges 2–99 - NCT07441681RecruitingPhase 3
Comparing radiation plus targeted therapy vs standard chemo for head and neck cancer
This trial compares two treatments for advanced head and neck cancer in patients who cannot take the drug cisplatin. One group gets radiation plus a targeted drug called cetuximab, the other gets radiation plus standard chemotherapy. The goal is to see which approach works better and is safer for people who are not candidates for cisplatin.
Beverly Hills, CaliforniaAges 18 years+ - NCT07597473RecruitingPhase 4
Dymista nasal spray for allergies in Chinese teens
This trial tests Dymista, a nasal spray combining an antihistamine and steroid, in teenagers aged 12–17 with moderate-to-severe allergic rhinitis (nasal allergies that disrupt sleep, school, or daily life). The study will see how well it works and if it's safe for this age group.
BeijingAges 12–17 - NCT07440290RecruitingPhase 2/Phase 3
Dabrafenib and trametinib for BRAF V600 cancers
This trial tests two targeted drugs (dabrafenib and trametinib) for patients whose cancer has a specific change in the BRAF gene called V600. These drugs work together to block signals that help the cancer grow. The trial is for children, teenagers, and adults with many types of cancer, except for a few common ones that already have approved treatments.
BelfastAges 1 year+ - NCT07688772RecruitingPhase 3
Study of SHR-1819 Injection for Seasonal Allergic Rhinitis
This trial tests a new injection called SHR-1819 for people with seasonal allergies who haven't responded well to standard treatments like nasal sprays or antihistamines. It aims to see if it can reduce allergy symptoms.
Beijing, Beijing MunicipalityAges 18–75 - NCT06283953Enrolling by invitation
Helping Caregivers Care for Kids with Tracheostomies at Home
This study offers help and training to caregivers of children with a tracheostomy who are getting ready to bring their child home from the hospital. The goal is to make caring for a child with a tracheostomy at home easier and safer.
La Jolla, CaliforniaAges 18 years+ - NCT07765186Recruiting
How sound and attention affect hearing with cochlear implants
This study tests how people focus on sounds in noisy situations, comparing those with normal hearing and those with cochlear implants. It aims to better understand how the brain processes sound, which could improve hearing technology.
Tampa, FloridaAges 18–90 - NCT06100393Recruiting
New sound processing for better hearing in cochlear implant users
This trial tests new sound-processing software in cochlear implants to help users hear speech better in noisy places. It may help adult implant users who struggle with conversations in background noise.
Melbourne, VictoriaAges 18 years+ - NCT07520162RecruitingPhase 3
Tezepelumab for Nasal Polyps in Chinese Adults
This study tests whether tezepelumab, a new injectable medicine, can help reduce nasal polyps and improve symptoms like nasal congestion, loss of smell, and sleep problems. You would receive the study drug while continuing your current nasal steroid spray, and your doctors would track how your symptoms change.
BeijingAges 18 years+ - NCT07420530RecruitingPhase 2
Exercise and breathing study for young adults with vocal cord issues
This study looks at how the vocal cords move during exercise in young adults who have trouble breathing while active. It may help researchers understand why this happens and how to better diagnose and treat it.
Bloomington, IndianaAges 18–26 - NCT04649242RecruitingPhase 3
Migraine pain relief study for kids and teens
This trial studies a medicine for stopping a migraine attack in children and teens. It may help families understand which treatment works best during acute (during-attack) migraine pain.
Birmingham, AlabamaAges 6–17 - NCT07762976RecruitingPhase 2
Tailoring chemo for nasopharyngeal cancer using EBV-DNA and MRI
This trial tests whether adjusting chemotherapy based on tumor markers (EBV-DNA) and MRI scans can improve outcomes and reduce side effects for people with nasopharyngeal cancer. If you have stage II or III disease, this study might help guide your treatment more precisely.
Shanghai, Shanghai MunicipalityAges 18–65 - NCT07029997Recruiting
Follow-up study of the Solo+ ear tube device
This study checks how well the Solo+ ear tube device works over time. If you or your child had the device placed to help with ear infections or fluid buildup, joining helps doctors learn how it performs.
Trieste, Trieste (TS)Ages 6 months+ - NCT05946577Recruiting
Links tinnitus and hearing changes after head and neck cancer treatment
This study looks at how tinnitus (ringing in the ears) and hearing problems may develop after radiotherapy alone or with certain chemotherapy for high-risk head and neck cancer. The goal is to better understand who is more likely to experience these side effects.
ParisAges 18 years+ - NCT06014710Recruiting
Studying swallowing function with new testing methods
This trial tests a new way to measure how well your throat and voice box work during swallowing. It may help doctors better understand swallowing problems and improve care.
BordeauxAges 18 years+ - NCT06915038Recruiting
Measuring tumor DNA in blood for HPV-positive throat cancer
This study looks at a blood test that finds DNA from HPV-related throat tumors. It may help doctors decide on surgery and check if the cancer is completely removed.
Carmel, IndianaAges 18 years+ - NCT05592626RecruitingPhase 1/Phase 2
T cell activator STAR0602 for advanced solid tumors
This study tests an experimental drug called STAR0602 that aims to boost your immune system's T cells to fight advanced solid tumors. It's for patients whose cancer has not responded to standard treatments or for whom such treatments are not suitable.
Sacramento, CaliforniaAges 18 years+ - NCT06495021Recruiting
Osteopathic manipulation for newly diagnosed respiratory illness in older adults
This study tests whether osteopathic manipulation (a gentle hands-on treatment) helps older adults recover from common respiratory illnesses like bronchitis or pneumonia when added to regular care. It may be a good option for you if you're 65 or older and have just been diagnosed with a respiratory infection.
Bloomsburg, PennsylvaniaAges 65–100 - NCT07754266Recruiting
Headache, ear, and dizziness registry
This study collects information from people who have headaches, ear problems, dizziness, or sinus issues to better understand these symptoms and how they relate to migraine. Your participation may help improve future treatments and diagnosis.
North Kingstown, Rhode IslandAges 18 years+ - NCT07417956Recruiting
Measuring reflex in cochlear implant for kids
This study tests a new way to program cochlear implants in children by measuring a tiny muscle reflex in the ear. This could help doctors set the sound levels more accurately without needing the child to respond.
Paris, Île-de-France RegionAges birth–7 years - NCT04971954Recruiting
Nicotine test to improve age-related hearing processing
This study tests whether nicotine can improve how your brain processes sounds, which can get worse with age. It’s designed for non-smokers without significant hearing or medical/medication issues.
Irvine, CaliforniaAges 18–85 - NCT07686211RecruitingEarly Phase 1
Study on better surgical guidance for head and neck cancer re-resection
This study tests a new augmented reality tool to help surgeons remove leftover tumor tissue after the first surgery. It might make re-resection more precise and improve cancer clearance.
Nashville, TennesseeAges Any age - NCT06840015Recruiting
Testing Airpod Pros as a hearing aid for mild to moderate loss
This study tests whether Apple Airpod Pros can work as an assistive hearing device for people with mild to moderate hearing loss. If you haven't used hearing aids before, you may be able to join and help find a new, affordable option.
Richardson, TexasAges 18–60 - NCT06846853RecruitingPhase 4
Comparing two contrast dyes for pituitary MRI
This trial compares two contrasting dyes (gadopiclenol and gadobutrol) used during pituitary MRI scans to see which one provides clearer images. It is for adults with known or suspected pituitary lesions that disrupt the blood-brain barrier.
Farmington, ConnecticutAges 19 years+
Common questions
- How many ear, nose & throat clinical trials are recruiting?
- Clin2 is tracking 1,367 recruiting otolaryngology studies from the U.S. registry right now, out of 2,201 we cover in this area in total.
- What does “Ear, nose & throat” cover here?
- Hearing, balance, and conditions of the ears, nose, sinuses, and throat. We group each study into ear, nose & throat based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a ear, nose & throat trial near me?
- Use the search to filter ear, nose & throat studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Mental health
- Digestive system
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.