Otolaryngology
Ear, nose & throat clinical trials
Hearing, balance, and conditions of the ears, nose, sinuses, and throat. We’re tracking 1,371 recruiting studies in this area right now.
By phase
- Not applicable978
- Phase 2168
- Phase 399
- Phase 146
- Phase 434
- Phase 1/Phase 232
- Phase 2/Phase 314
Top conditions
- Nasopharyngeal Carcinoma80
- Dysphagia73
- Hearing Loss61
- Tinnitus31
- Hearing Loss, Sensorineural25
- Nasopharyngeal Carcinoma (NPC)24
- Allergic Rhinitis23
- Head and Neck Cancer22
- Oropharynx Cancer21
- Stroke20
- Sensorineural Hearing Loss18
- Nasopharyngeal Cancinoma (NPC)17
- Chronic Rhinosinusitis With Nasal Polyps15
- Oropharyngeal Cancer15
- Nasopharyngeal Cancer14
- Vestibular Schwannoma14
- Head and Neck Squamous Cell Carcinoma13
- Chronic Rhinosinusitis (CRS)12
Leading sponsors
- Sun Yat-sen University59
- Eye & ENT Hospital of Fudan University17
- Cairo University15
- Assistance Publique - Hôpitaux de Paris14
- NYU Langone Health14
- Mayo Clinic12
- National Cancer Institute (NCI)12
- Johns Hopkins University11
- Ming-Yuan Chen11
- Cochlear9
Where studies are running
- California62
- Maryland37
- New York35
- Florida30
- Massachusetts21
- Illinois20
- Texas18
- Arizona17
- Colorado16
- Alabama15
Recruiting studies1,371 total
- NCT06982300RecruitingPhase 1/Phase 2
PET scan for advanced nasopharyngeal cancer
This trial tests a special PET scan that can detect a receptor (SSTR2) on cancer cells to see if it can help guide treatment for people with nasopharyngeal cancer (a type of head and neck cancer). It may help doctors choose the best therapy for you.
GroningenAges 18 years+ - NCT06982716Recruiting
Community hearing aid fitting study for adults
This trial tests if community health workers can use smartphones to fit hearing aids for adults with mild to severe hearing loss in low-income communities. It aims to make hearing care more accessible.
Pretoria, GautengAges 18 years+ - NCT06984861RecruitingPhase 2
Reduced radiation with chemo for HPV-related throat cancer
This trial tests if giving less radiation along with chemotherapy is safe and effective for people with HPV-positive throat cancer. It aims to reduce side effects while still controlling the cancer.
Basking Ridge, New JerseyAges 18 years+ - NCT06988215Recruiting
Taping and swallowing exercises for stroke patients with swallowing difficulty
This trial tests whether kinesiology taping (a special tape placed on the skin) combined with swallowing exercises can help people who have had a stroke and have trouble swallowing. It may improve muscle thickness and swallowing function.
Istanbul, bahçelievlerAges 50–80 - NCT06997068RecruitingPhase 2
Drug combination for returning head and neck cancer
This trial tests a combination of three drugs—methotrexate, erlotinib, and celecoxib—for people whose head and neck cancer has come back or spread. It is designed for patients in the rural Midwest who have already had or chosen not to have standard first treatment.
Rochester, MinnesotaAges 18 years+ - NCT06999577RecruitingPhase 4
The Mechanism Versus PPI Trial for throat reflux
This study tests how well omeprazole (a common acid-blocking medicine) works for people with laryngopharyngeal reflux (LPR), a condition where stomach acid irritates the throat. If you have had throat symptoms for more than 8 weeks and are already scheduled for an endoscopy with acid monitoring, you may qualify to see if this medicine helps more than a placebo.
San Deigo, CaliforniaAges 18–89 - NCT07000643RecruitingPhase 3
Proton vs. standard radiation for nasopharyngeal cancer
This trial compares two types of radiation therapy—proton beam versus standard X-ray (photon)—for treating nasopharyngeal cancer. The goal is to see if proton therapy works as well as standard therapy while possibly causing fewer side effects.
JinanAges 18–75 - NCT07011927Recruiting
Testing a new electrode placement during cochlear implant surgery
This study is testing a safe way to place an extra electrode near a nerve in your ear during cochlear implant surgery. The goal is to see if this can improve hearing outcomes.
New York, New YorkAges 18 years+ - NCT07019870Recruiting
Screening for early diagnosis of nose cancer
This trial offers free screening to find nose cancer (nasopharyngeal carcinoma or NPC) early, before symptoms start. It is for people with a family history of NPC who may be at higher risk.
SingaporeAges 35–60 - NCT07021586Recruiting
Tongue pressure in adults with chronic neck pain
This study looks at how tongue pressure might be related to chronic neck pain in people aged 50 to 65. If you have ongoing neck pain, it could help researchers understand how your muscles work.
TaipeiAges 50–65 - NCT07028658Recruiting
Lip-reading therapy for people with hearing aids
This trial tests whether speech therapy that focuses on lip-reading can help people with hearing aids better understand speech in noisy places. You'll attend two therapy sessions each week and see if your listening improves.
ParisAges 18 years+ - NCT07029594Recruiting
Thermal spa for Primary Ciliary Dyskinesia (PCD)
This trial tests whether a stay at a thermal spa can improve symptoms of Primary Ciliary Dyskinesia (PCD), a genetic lung condition. It's for adults with stable PCD who haven't had a recent infection or spa treatment.
NiceAges 18 years+ - NCT07033091Recruiting
HPV screening study for healthy adults 40 and older
This study checks healthy adults aged 40+ for HPV in the mouth using a simple gargle rinse. It aims to see if this can help find early signs of oropharyngeal cancer.
BrnoAges 40 years+ - NCT07033221Recruiting
Balance and inner ear function in obesity
This study looks at how obesity affects your sense of balance (vestibular function). It compares people with obesity who are candidates for weight-loss surgery to people without obesity, to see if weight affects balance.
Istanbul, KüçükçekmeceAges 18–60 - NCT07035314Recruiting
Comparing medicines for pain after tonsil removal in children
This study compares two ways to manage pain after tonsil removal in children: a medication given by mouth or injection versus a medication applied directly to the surgical site. The goal is to find which approach works better for pain control.
CairoAges 4–10 - NCT07039500Recruiting
Severe sleep apnea's impact on hearing and thinking
This study looks at how severe sleep apnea affects your brain's ability to process sounds and think clearly. You will have hearing tests and an EEG, which is a safe brainwave recording, to see if treating sleep apnea can help your hearing and thinking.
Beijing, Beijing MunicipalityAges 20–60 - NCT07048418Recruiting
Nose job results in adults born with a cleft lip and palate
This trial asks adults who had a nose job as teens or children, after being born with a cleft lip and palate, to rate how they look and feel about their nose. Their answers will help doctors understand how these surgeries affect patients long-term.
MontpellierAges 18–30 - NCT07055542Recruiting
New tool to predict thunderstorm asthma risk
This research study aims to create a simple tool to predict who is at risk for thunderstorm asthma. You will be asked to track your allergy symptoms and medications online during the spring, plus do a lung function test and give a blood sample.
Albury, New South WalesAges 18–70 - NCT07056582Recruiting
Pain relief before nasal surgery: ketamine vs. dexmedetomidine
This trial tests two inhaled medicines given before surgery to see which one works better for pain after nasal surgery. One medicine is ketamine and the other is dexmedetomidine, both given as a mist through a nebulizer.
SohagAges 20–60 - NCT07059351Recruiting
Mouth health and pneumonia risk after stroke
This study looks at how oral health affects the chances of developing pneumonia after a stroke and how well people recover their ability to swallow. It may help find ways to prevent complications and improve recovery for stroke survivors with swallowing problems.
GhentAges 18 years+ - NCT07063212RecruitingPhase 2
Sacituzumab govitecan plus cetuximab for head and neck cancer
This trial tests a combination of two drugs—sacituzumab govitecan and cetuximab—for people with advanced head and neck cancer that has gotten worse after immunotherapy. The goal is to see if this new treatment can shrink or slow the cancer.
Basking Ridge, New JerseyAges 18 years+ - NCT07067268RecruitingPhase 2
Tislelizumab and capecitabine for nasopharyngeal cancer with remaining EBV DNA
This trial tests a combination of two drugs, tislelizumab and capecitabine, for people with nasopharyngeal cancer who still have detectable EBV DNA in their blood after finishing radiation therapy. The goal is to see if this treatment can help clear the virus and improve outcomes.
Shanghai, ChinaAges 18 years+ - NCT07070479RecruitingPhase 2
Combination treatment for PD-1 resistant nasopharyngeal cancer
This trial is testing a combination of drugs for people whose nasopharyngeal cancer has stopped responding to standard treatments like platinum chemotherapy and PD-1 inhibitors. It aims to find a new effective approach for advanced or recurrent disease.
Guangzhou, GuangdongAges 18–70 - NCT07071480Recruiting
Noninvasive sound therapy for chronic tinnitus
This trial tests a noninvasive device to reduce the loudness and burden of chronic tinnitus. It may help people who have constant tinnitus and are not currently using other treatments.
Miami, FloridaAges 18 years+
Common questions
- How many ear, nose & throat clinical trials are recruiting?
- Clin2 is tracking 1,371 recruiting otolaryngology studies from the U.S. registry right now, out of 2,216 we cover in this area in total.
- What does “Ear, nose & throat” cover here?
- Hearing, balance, and conditions of the ears, nose, sinuses, and throat. We group each study into ear, nose & throat based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a ear, nose & throat trial near me?
- Use the search to filter ear, nose & throat studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Mental health
- Digestive system
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.