Otolaryngology
Ear, nose & throat clinical trials
Hearing, balance, and conditions of the ears, nose, sinuses, and throat. We’re tracking 1,371 recruiting studies in this area right now.
By phase
- Not applicable978
- Phase 2168
- Phase 399
- Phase 146
- Phase 434
- Phase 1/Phase 232
- Phase 2/Phase 314
Top conditions
- Nasopharyngeal Carcinoma80
- Dysphagia73
- Hearing Loss61
- Tinnitus31
- Hearing Loss, Sensorineural25
- Nasopharyngeal Carcinoma (NPC)24
- Allergic Rhinitis23
- Head and Neck Cancer22
- Oropharynx Cancer21
- Stroke20
- Sensorineural Hearing Loss18
- Nasopharyngeal Cancinoma (NPC)17
- Chronic Rhinosinusitis With Nasal Polyps15
- Oropharyngeal Cancer15
- Nasopharyngeal Cancer14
- Vestibular Schwannoma14
- Head and Neck Squamous Cell Carcinoma13
- Chronic Rhinosinusitis (CRS)12
Leading sponsors
- Sun Yat-sen University59
- Eye & ENT Hospital of Fudan University17
- Cairo University15
- Assistance Publique - Hôpitaux de Paris14
- NYU Langone Health14
- Mayo Clinic12
- National Cancer Institute (NCI)12
- Johns Hopkins University11
- Ming-Yuan Chen11
- Cochlear9
Where studies are running
- California62
- Maryland37
- New York35
- Florida30
- Massachusetts21
- Illinois20
- Texas18
- Arizona17
- Colorado16
- Alabama15
Recruiting studies1,371 total
- NCT07183826Recruiting
Online mindfulness therapy for chronic tinnitus
This trial tests an online mindfulness program (iMBCT) to help people with chronic tinnitus manage their symptoms. If you have had tinnitus for at least 3 months and it bothers you, you may be able to join from home.
WarsawAges 18 years+ - NCT07184892Recruiting
Swallowing therapy after stroke
This study tests if watching swallowing movements (action observation therapy) helps people recover swallowing function after a first-time stroke. It uses a brain imaging technique called fNIRS to see how the brain responds.
Jinan, ShandongAges 18–80 - NCT07188584RecruitingPhase 3
Smaller radiation vs. standard after chemo-immunotherapy for advanced nasopharyngeal cancer
This trial tests whether a smaller radiation treatment area is as effective as the usual larger one for people whose metastatic nasopharyngeal cancer has responded well to first-line chemotherapy plus immunotherapy. It aims to reduce side effects while keeping the cancer under control.
ZhuhaiAges 18–70 - NCT07192757Recruiting
Trial to help you hear speech in noisy places
This study tests a new way to help people with age-related hearing loss understand conversations in noisy environments. It might improve your ability to hear clearly when there is background noise.
Gainesville, FloridaAges 55–80 - NCT07195383Recruiting
Safe swallowing check after breathing tube removal in ICU
This study tests a special nutrition program for patients who just had a breathing tube removed in the ICU. It aims to see if a safe swallowing check can help prevent problems and make feeding safer.
IstanbulAges 18 years+ - NCT07198568Recruiting
Swallowing and Neck Muscle Activity in Sarcopenic Dysphagia
This study looks at how the muscles in your neck and throat work when you swallow, specifically in older adults who have both sarcopenia (low muscle mass) and trouble swallowing. The goal is to better understand the connection between swallowing and muscle activity, which may help develop better treatments.
Incheon, Jung-guAges 65 years+ - NCT07205354Recruiting
Food preference tool for older hospital patients
This study is creating a tool to better understand what foods older patients prefer, especially those with swallowing difficulties. It could help hospitals make meals more enjoyable and safer for you.
LyonAges 70 years+ - NCT07209189RecruitingPhase 2
Chemo and immunotherapy before surgery for head and neck cancer
This trial tests a combination of chemotherapy and an immunotherapy drug called Toripalimab before surgery for certain head and neck cancers. The goal is to see if this approach can reduce the extent of treatment needed while still being effective.
Baltimore, MarylandAges 18 years+ - NCT07211711Recruiting
Splint therapy for tinnitus linked to jaw joint issues
This trial tests if a custom mouthpiece (occlusal splint) can relieve ringing in the ears (tinnitus) that started along with jaw or face pain (TMD). It aims to see if stabilizing the jaw helps reduce both the noise in your ears and the discomfort.
São Paulo, São PauloAges 18 years+ - NCT07212530Recruiting
EmoTIChealth: A game to boost teen health
This trial tests a serious video game designed to help teenagers learn skills for better health. It's for 12- to 16-year-olds who speak Spanish and have internet access.
Valencia, ValenciaAges 12–16 - NCT07216430RecruitingPhase 2
Safety and efficacy of a pneumococcal vaccine in young kids
This study tests a new pneumococcal vaccine (wSp) in young children who have already had 3 doses of a standard pneumococcal shot. It aims to see if the new vaccine is safe and works well to protect against serious infections.
Pittsford, New YorkAges 5 months–7 months - NCT07217938RecruitingPhase 2
Testing statins for swallowing problems after radiation
This study tests whether a common cholesterol-lowering drug (pravastatin, a type of statin) can reduce swallowing problems caused by past radiation for head and neck cancer. If you have had radiation at least 2 years ago and still have trouble swallowing, this trial may help find a new way to ease those symptoms.
Melbourne, VictoriaAges 18 years+ - NCT07218913RecruitingPhase 1
Testing a drug to reduce ear damage from chemo in testicular cancer
This trial tests whether adding Pedmark (sodium thiosulfate) to cisplatin chemotherapy can protect hearing in men with stage II or III testicular germ cell tumors. It aims to reduce the risk of drug-related ear damage while still treating the cancer.
Duarte, CaliforniaAges 18 years+ - NCT07219849RecruitingPhase 2
Testing a new nasal spray for seasonal allergies
This study tests a new nasal spray (ALDP001) in adults with seasonal allergies to ragweed. It aims to find the best dose and how often to use it.
Mississauga, OntarioAges 18–65 - NCT07222202Recruiting
Testing flexible hearing aids for hearing loss
This study tests flexible hearing aids for people with conductive or mixed hearing loss (where sound is blocked or not transmitted well to the inner ear). It aims to see if these devices work well and are comfortable for daily use.
Winston-Salem, North CarolinaAges 6 months–80 years - NCT07226167Recruiting
Hearing aid benefit in noisy places
This study tests how well hearing aids help people hear in real-world noisy environments. If you already use hearing aids and have hearing loss in both ears that started after childhood, this trial may help understand how to improve your experience.
Madison, WisconsinAges 18 years+ - NCT07228845Recruiting
Comparing 3D-printed vs. standard ear tips for hearing loss
This study tests whether a custom 3D-printed ear tip is more comfortable than a regular one for people with hearing loss. If you wear hearing aids or are considering them, this could help make the fit better.
Tucson, ArizonaAges 18–89 - NCT07230236Recruiting
Hidden hearing loss: brain waves and speech in noise
This study explores a possible condition called 'hidden hearing loss' – where you struggle to hear in noisy situations despite passing a standard hearing test. It uses a special brain-wave test (LS Chirp ABR) to see if there is a link between your brain's response and how well you understand speech in noise.
IstanbulAges 20–60 - NCT07235488Recruiting
Integrative Medicine for Sudden Hearing Loss
This trial tests a combination of treatments (integrative medicine) for people who have just lost their hearing suddenly. It may help improve hearing recovery if started early.
TaichungAges 18 years+ - NCT07245329Recruiting
Expanded sinus surgery with throat tissue ablation for nasal polyps
This trial tests a more thorough sinus surgery combined with removing lymphoid tissue in the throat to see if it helps people with nasal polyps. Researchers want to know if this approach reduces inflammation and improves symptoms.
Wuhan, HubeiAges 18–65 - NCT07248956RecruitingPhase 2
Chemo plus immunotherapy before surgery for throat cancer
This trial tests giving chemotherapy combined with an immunotherapy drug (finotonlimab) before surgery for locally advanced hypopharyngeal cancer. It aims to shrink the tumor enough to improve surgery outcomes.
Harbin, HeilongjiangAges 18–75 - NCT07681973Recruiting
Smell training for loss of smell in sinus patients
This study tests whether smell training can improve your sense of smell and affect your immune system. It is for people with chronic sinus inflammation and nasal polyps who have lost their sense of smell.
Cleveland, OhioAges 18 years+ - NCT07576582Recruiting
Mud therapy for jaw joint pain
This trial tests whether a special mud treatment (peloid therapy) can reduce jaw joint pain and improve function in people with temporomandibular joint disorder. It is a non-drug approach that may help those who have had jaw pain for at least 4 weeks.
Uşak, MerkezAges 18–65 - NCT05451628Recruiting
Personalized Sound Processor Tuning for New Cochlear Implant Users
This study tests a personalized way to program your cochlear implant sound processor based on your unique ear anatomy. It's for adults who have recently received a MED-EL implant and haven't turned it on yet.
Brussels, Brussels CapitalAges 18 years+
Common questions
- How many ear, nose & throat clinical trials are recruiting?
- Clin2 is tracking 1,371 recruiting otolaryngology studies from the U.S. registry right now, out of 2,216 we cover in this area in total.
- What does “Ear, nose & throat” cover here?
- Hearing, balance, and conditions of the ears, nose, sinuses, and throat. We group each study into ear, nose & throat based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a ear, nose & throat trial near me?
- Use the search to filter ear, nose & throat studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Mental health
- Digestive system
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.