Ophthalmology
Eyes & vision clinical trials
Eye disease and conditions that affect sight. We’re tracking 1,764 recruiting studies in this area right now.
By phase
- Not applicable1,204
- Phase 3133
- Phase 2119
- Phase 1117
- Phase 492
- Phase 1/Phase 285
- Phase 2/Phase 314
Top conditions
- Glaucoma107
- Myopia88
- Cataract76
- Diabetic Retinopathy51
- Dry Eye38
- Keratoconus34
- Retinitis Pigmentosa33
- Age-Related Macular Degeneration31
- Amblyopia26
- Eye Diseases24
- Graves Disease24
- Sjogren's Syndrome24
- Dry Eye Disease (DED)23
- Multiple Sclerosis22
- Astigmatism21
- Ocular Hypertension21
- Diabetic Macular Edema20
- Macular Degeneration20
Leading sponsors
- Zhongshan Ophthalmic Center, Sun Yat-sen University25
- Medical University of Vienna20
- Second Affiliated Hospital, Zhejiang University, School of Medicine19
- Fondation Ophtalmologique Adolphe de Rothschild18
- Assistance Publique - Hôpitaux de Paris16
- National Taiwan University Hospital16
- The Hong Kong Polytechnic University16
- Eye & ENT Hospital of Fudan University15
- National Eye Institute (NEI)15
- Shanghai Eye Disease Prevention and Treatment Center15
Where studies are running
- California133
- Arizona68
- Florida43
- Maryland39
- Texas37
- New York36
- Massachusetts35
- Alabama26
- North Carolina20
- Pennsylvania20
Recruiting studies1,764 total
- NCT07695207RecruitingPhase 3
Testing SMZ1 with ranibizumab for wet macular degeneration
This trial tests a new medicine called SMZ1 combined with ranibizumab (a standard treatment) for people with wet macular degeneration. It may help improve vision by targeting the cause of the disease more effectively.
Seoul, SeoulAges 50 years+ - NCT07694375RecruitingPhase 2
Eye drop study to protect corneal cells after cataract surgery
This trial tests an eye drop called CA201A to see if it can prevent loss of cells in the clear front layer of the eye (the cornea) after cataract surgery. The drop contains ascorbic acid, a form of vitamin C, and is given before and after the procedure to help protect the eyesight.
Deakin, Australian Capital TerritoryAges 18–85 - NCT06017362RecruitingPhase 4
Insulin drops for dry eye in glaucoma patients
This study tests whether insulin eye drops can safely help dry eye in people who also use eye drops for glaucoma. It may offer a new option if you have both conditions and your eye pressure is stable.
Madrid, MadridAges 18 years+ - NCT07696130Recruiting
Trifocal lens implant study for cataract or presbyopia
This study tests a new type of trifocal lens implant to see how well it improves vision at all distances after cataract or lens replacement surgery. It may help you become less dependent on glasses.
Szczecin, ZachodnipomorskieAges 50–75 - NCT07695298RecruitingPhase 4
Testing faricimab for a rare eye disease linked to histoplasmosis
This trial tests a drug called faricimab (brand name Vabysmo) for treating abnormal blood vessel growth in the back of the eye, caused by a past infection with histoplasmosis. The goal is to see if it helps improve vision over 52 weeks.
Cincinnati, OhioAges 18 years+ - NCT07693829Recruiting
Smart bed-exit alert for cataract surgery patients
This trial tests a smart bed-exit alert device to help detect when patients get out of bed before eye surgery. It aims to improve safety in the operating room.
TaipeiAges 18 years+ - NCT07693205RecruitingPhase 4
Comparing two lens types for cataract surgery with astigmatism
This study compares two types of artificial lenses placed during cataract surgery to see which one gives better vision for people with cataracts and astigmatism. You will receive the same type of lens in both eyes.
Sugar Land, TexasAges 22 years+ - NCT07690813Recruiting
AI model to predict nearsightedness with a non-dilated eye exam
This study uses an AI model to predict your nearsightedness prescription using a quick, non-dilated eye exam instead of the usual dilated exam. If you are between 18 and 60, have nearsightedness, and no major eye surgeries or conditions, you may be a good fit.
JiangxiAges 18–47 - NCT07691463Recruiting
How light-sensitive cells help your eye focus
This trial studies how different types of light-sensitive cells in your eye work to help you focus. It involves sitting still and looking at lights while measurements are taken.
Rochester, New YorkAges Up to 35 years - NCT02576483Recruiting
Compare LASIK, SMILE, and PRK for eye prescription correction
This study compares three laser eye surgeries—LASIK, SMILE, and PRK—to see which works best for people who have similar eye prescription needs. You may be a good fit if you’ve never had vision-correcting surgery before and you meet the eye-health safety checks.
Palo Alto, CaliforniaAges 21–62 - NCT05927428RecruitingPhase 2
Eye drops for neurotrophic corneal ulcers
This Phase 2 trial tests BRM424 eye drops in adults with neurotrophic keratitis (a weakened, slow-healing cornea) to see if they help and are safe over 28 days. You may be able to join if your condition matches Stage 2 or Stage 3 and you meet the safety rules.
Leland, North CarolinaAges 18 years+ - NCT07682025Enrolling by invitation
Imaging and eye model for PVR study
This study uses eye scans and computer models to better understand and predict a condition called proliferative vitreoretinopathy (PVR), which can cause vision problems after eye surgery. If you already took part in specific studies that collected your eye images, this trial may analyze those images with artificial intelligence (AI).
LondonAges 18 years+ - NCT07688538Recruiting
Mapping vision system development in embryos
This trial studies embryos to understand how the visual system develops normally and abnormally. It compares tissues from embryos with developmental problems to healthy ones, aiming to create a detailed map of early vision system growth.
Guangzhou, GuangdongAges Any age - NCT07682896RecruitingPhase 2
Testing YB-101 for safety and effectiveness in Graves' disease
This trial tests an investigational drug called YB-101 for people with Graves' disease, whether or not they have thyroid eye disease. The goal is to see if the drug is safe and can help.
Gilbert, ArizonaAges 18 years+ - NCT04846140Recruiting
Non-invasive brain stimulation to help side vision in glaucoma
This study tests a non-invasive brain stimulation treatment to see if it can improve peripheral (side) vision in people with open-angle or normal-tension glaucoma. It targets people whose central vision is still relatively preserved but whose side vision has a measurable “gap” on vision testing.
Hong KongAges 18–80 - NCT05874258Recruiting
Electric brain stimulation plus vision training for glaucoma
This trial tests whether combining a short vision learning program with non-invasive electrical stimulation to the brain can improve vision in people with open-angle or normal-tension glaucoma. It may help by training the visual system while stimulating brain pathways to support vision.
Hong KongAges 18–80 - NCT04561557RecruitingEarly Phase 1
Cell therapy for relapsing nervous system autoimmune diseases
This early-phase trial tests CT103A “CAR-T” cell therapy to treat certain relapsing or treatment-resistant autoimmune diseases that affect the nervous system. It aims to see whether the cells are safe and may help reduce disease activity when standard treatments haven’t controlled symptoms.
Wuhan, HubeiAges 18–75 - NCT05039684Recruiting
Testing eye-surface inflammation in glaucoma or high eye pressure
This study measures inflammation markers on the eye surface in people with primary open-angle glaucoma or ocular hypertension who use certain glaucoma drops. The results may help doctors understand how these drops affect the eye and inflammation.
ValladolidAges 18–99 - NCT07675811RecruitingPhase 3
Study of a new treatment for cat allergy related eye symptoms
This trial tests an injectable treatment that may help manage eye allergy symptoms caused by cat allergies. It aims to see if the treatment is safe and effective for adults and children, and includes a controlled cat exposure challenge.
Andover, MassachusettsAges 8 years+ - NCT07676084RecruitingPhase 4
Over-the-counter lubricating eye drops for dry eye
This study tests whether over-the-counter lubricating eye drops can improve dry eye symptoms and eye comfort. It compares the drops to no treatment to see how well they work.
Andover, MassachusettsAges 18 years+ - NCT07679412Recruiting
CMV Retinitis Trial: Your Own Cells vs. Resistant Virus
This trial tests a new treatment made from your own immune cells (called LB-DTK-CMV) for a type of CMV eye infection that is not getting better with standard antiviral drugs. The goal is to see if these cells can safely control the infection and improve your vision.
SeoulAges 19 years+ - NCT07675824RecruitingPhase 1/Phase 2
New treatment for open-angle glaucoma or high eye pressure
This trial tests an investigational drug called REGN22530 for people with mild to moderate primary open-angle glaucoma or ocular hypertension (high eye pressure). The goal is to see if it can safely lower eye pressure and protect vision.
Deerfield Beach, FloridaAges 18 years+ - NCT07680244Recruiting
Testing a new tool to see retina in eye scans
This trial is testing a new software tool that helps doctors see and assess different parts of the retina in eye scans. It aims to see how well the tool works in people with and without certain retina conditions.
Tucson, ArizonaAges 18 years+ - NCT07674290RecruitingPhase 4
Study of MC4R Agonist for Bardet-Biedl Syndrome and Genetic Obesity
This trial tests a drug called setmelanotide for people with Bardet-Biedl Syndrome (a rare genetic condition) or other severe genetic obesity. It looks at how well the drug works in real-world settings, not just in a lab.
EssenAges Any age
Common questions
- How many eyes & vision clinical trials are recruiting?
- Clin2 is tracking 1,764 recruiting ophthalmology studies from the U.S. registry right now, out of 2,747 we cover in this area in total.
- What does “Eyes & vision” cover here?
- Eye disease and conditions that affect sight. We group each study into eyes & vision based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a eyes & vision trial near me?
- Use the search to filter eyes & vision studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
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Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.