Ophthalmology
Eyes & vision clinical trials
Eye disease and conditions that affect sight. We’re tracking 1,819 recruiting studies in this area right now.
By phase
- Not applicable1,253
- Phase 3132
- Phase 2121
- Phase 1120
- Phase 492
- Phase 1/Phase 285
- Phase 2/Phase 316
Top conditions
- Glaucoma108
- Cataract89
- Myopia89
- Diabetic Retinopathy52
- Dry Eye42
- Keratoconus34
- Age-Related Macular Degeneration33
- Retinitis Pigmentosa31
- Sjogren's Syndrome29
- Diabetic Macular Edema26
- Eye Diseases26
- Graves Disease26
- Amblyopia24
- Astigmatism23
- Dry Eye Disease (DED)23
- Multiple Sclerosis23
- Retinal Disease23
- Ocular Hypertension22
Leading sponsors
- Zhongshan Ophthalmic Center, Sun Yat-sen University28
- Second Affiliated Hospital, School of Medicine, Zhejiang University23
- Medical University of Vienna19
- Fondation Ophtalmologique Adolphe de Rothschild18
- National Taiwan University Hospital17
- Assistance Publique - Hôpitaux de Paris16
- Eye & ENT Hospital of Fudan University15
- National Eye Institute (NEI)15
- Shanghai Eye Disease Prevention and Treatment Center15
- Duke University13
Where studies are running
- California141
- Arizona66
- Texas41
- Maryland39
- Massachusetts34
- New York34
- Florida32
- Alabama27
- North Carolina21
- Pennsylvania20
Recruiting studies1,819 total
- NCT05885503RecruitingPhase 3
Testing an eye injection for diabetic macular swelling
This Phase 3 study compares a new eye injection (RC28-E) with the standard treatment (aflibercept) for diabetic macular edema, which is swelling in the central retina that affects vision. It aims to see whether the new treatment works as well and is safe.
Beijing, Beijing MunicipalityAges 18 years+ - NCT05736757Recruiting
tPA eye treatment for serious bleeding after eye rupture
This trial looks at whether a medicine called tPA can help treat serious bleeding in or behind the eye after a severe eye injury. It may help your doctors improve bleeding resolution and protect vision after rupture-type injuries.
Hangzhou, ZhejiangAges 18–80 - NCT07281391Recruiting
Laser treatment for pigmentary glaucoma
This trial tests a laser procedure called DSLT to lower eye pressure in people with pigmentary glaucoma. It may offer a treatment option for those who have not had prior glaucoma surgeries.
Houston, TexasAges Any age - NCT07275840RecruitingPhase 2
Testing IBI302 for wet age-related macular degeneration
This study tests a new medicine called IBI302 for wet age-related macular degeneration (AMD). It aims to slow vision loss by targeting both blood vessel growth and inflammation. You might qualify if you have active wet AMD and have not had certain injections recently.
Shanghai, Shanghai MunicipalityAges 50 years+ - NCT06926686Recruiting
Tissue graft vs own cartilage for lower eyelid lift
This study compares two different surgical materials to fix a lower eyelid that is sagging or pulled down. It uses either a donated tissue product (acellular dermal matrix) or a piece of your own eyelid cartilage to help lift the eyelid back into place.
Bergen, VetslandetAges 18–75 - NCT07272005Recruiting
Improving control of intermittent exotropia
This trial tests ways to improve control of intermittent exotropia, a type of eye misalignment that comes and goes, without surgery for at least 6 months.
Dallas, TexasAges 4–10 - NCT06514612RecruitingPhase 3
Eye drop study for droopy eyelids in adults
This study tests a new eye drop (oxymetazoline) to see if it can help lift droopy eyelids in adults. To join, you must have a certain amount of eyelid droop and some vision loss in your upper field of view, and you should feel that the droop bothers you enough to want treatment.
PardubiceAges 18–75 - NCT06311617Recruiting
Eye Blood Vessel Changes During Pregnancy
This observational study monitors changes in the blood vessels of your retina (the light-sensitive tissue at the back of the eye) during pregnancy. Researchers want to see how pregnancy affects the eyes, which might help better understand overall health.
Nashville, TennesseeAges 18 years+ - NCT07262125Enrolling by invitation
Carbon dioxide pressure and eye nerve sheath in kidney surgery
This study looks at how the carbon dioxide gas used during keyhole kidney cancer surgery affects the pressure behind your eye. The goal is to see if changes in gas pressure influence the nerve sheath that surrounds the optic nerve.
Istanbul, AtaşehirAges 31–69 - NCT07260097Recruiting
Eye imaging study after retinal detachment surgery
This study looks at how blood flow changes in the eye after a type of retinal detachment surgery called scleral buckling. It uses imaging to check the eye's blood vessels, and may help doctors understand recovery better.
SingaporeAges 21 years+ - NCT07258212Recruiting
Safety and normal vision data study with Neos device
This study is testing a device called Neos to gather safety information and normal vision data. It includes both healthy volunteers and people with eye or brain conditions, helping researchers understand how vision and eye movements work.
Bern, Canton of BernAges 3 years+ - NCT07362043Recruiting
Laser tool for cataract surgery
This study tests a handheld laser device used during cataract surgery to create a precise opening in the lens capsule. It may help surgeons improve accuracy and safety during the procedure.
Saint-HerblainAges 18 years+ - NCT07215390RecruitingPhase 2
Study of APL-3007 plus Syfovre for geographic atrophy
This trial tests whether a new drug called APL-3007, when added to your current Syfovre treatment, can slow the progression of geographic atrophy (an advanced form of dry age-related macular degeneration). It's for people who have already been on Syfovre for at least 6 months.
Gilbert, ArizonaAges 60 years+ - NCT07392255RecruitingPhase 1/Phase 2
Testing CTx001 for geographic atrophy (GA) in AMD
This trial is testing a new treatment called CTx001 for people with geographic atrophy (GA), a late stage of dry age-related macular degeneration (AMD). The goal is to see if the treatment is safe and can slow vision loss.
Carmel, IndianaAges 55 years+ - NCT05626920RecruitingPhase 1/Phase 2
Disulfiram trial for inherited vision loss in one eye
This early-stage study tests whether disulfiram can help preserve vision in people with inherited retinal degeneration. It focuses on one study eye and uses strict eye, blood/liver, and alcohol-avoidance rules because the medicine can affect the body and needs careful safety monitoring.
Seattle, WashingtonAges 18 years+ - NCT07225244Recruiting
Comparing balloon inflation points for tear duct surgery
This trial tests whether using four balloon inflation points during tear duct surgery works better than the standard two points for people with blocked tear ducts. It aims to improve tear drainage and reduce symptoms.
TaipeiAges 20 years+ - NCT07208318RecruitingEarly Phase 1
Restructuring brain signals for aging vision
This study tests a new way to help older adults improve their vision by retraining how the brain processes visual information. It may help with age-related vision changes.
Boston, MassachusettsAges 18 years+ - NCT06874452RecruitingPhase 4
Anti-anxiety pill for second cataract surgery
This study tests if giving the anti-anxiety pill alprazolam (XANAX) before your second cataract surgery helps reduce anxiety and improve satisfaction with the procedure.
TaipeiAges 18–80 - NCT06850571RecruitingPhase 4
Comparing two eye injections for diabetic macular edema
This trial compares two standard anti-VEGF injections (aflibercept and bevacizumab) for people with diabetic macular edema who have not recently had this treatment. The goal is to see which drug works better over three monthly doses to improve vision and reduce retinal swelling.
BaghdadAges 40 years+ - NCT07146828Recruiting
High-precision vision test for laser eye surgery
This trial tests a very precise way to measure vision (0.05 diopter steps) for people getting SMILE laser eye surgery. The goal is to see if this fine-tuning leads to better results.
Nantong, JiangsuAges 18–40 - NCT07142785Recruiting
Peeling or Not Peeling for Idiopathic Epiretinal Membrane Surgery
This study compares two surgical approaches for treating an idiopathic epiretinal membrane (a thin layer of scar tissue on the retina). It aims to see whether peeling the inner layer of the retina during surgery leads to better vision and fewer visual distortions.
Hangzhou, ZhejiangAges 18 years+ - NCT07127939Recruiting
AI eye test for traditional Chinese medicine body type
This study uses eye photos and artificial intelligence to figure out your traditional Chinese medicine body type. It may help doctors understand your health better without extra poking or prodding.
Nanchang, JiangxiAges 18–45 - NCT07273747Recruiting
Kelulut honey for eye allergy and dry eye
This study tests if Kelulut honey eye drops can help people with both allergic conjunctivitis (eye allergies) and dry eye symptoms. If you have been diagnosed with eye allergies and still have bothersome symptoms despite treatment, this trial may offer a natural option to explore.
Kota Bharu, KelantanAges 18–40 - NCT03683251RecruitingPhase 3
Extension study for a refillable eye implant plus ranibizumab
This trial studies whether continuing treatment with a refillable eye implant (Port Delivery System) and ranibizumab injection helps control a specific type of wet macular degeneration. It’s mainly for people who already finished an earlier related study and are able to keep up with frequent eye checks and procedures.
Phoenix, ArizonaAges 50 years+
Common questions
- How many eyes & vision clinical trials are recruiting?
- Clin2 is tracking 1,819 recruiting ophthalmology studies from the U.S. registry right now, out of 2,909 we cover in this area in total.
- What does “Eyes & vision” cover here?
- Eye disease and conditions that affect sight. We group each study into eyes & vision based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a eyes & vision trial near me?
- Use the search to filter eyes & vision studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Mental health
- Digestive system
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.