Ophthalmology
Eyes & vision clinical trials
Eye disease and conditions that affect sight. We’re tracking 1,764 recruiting studies in this area right now.
By phase
- Not applicable1,204
- Phase 3133
- Phase 2119
- Phase 1117
- Phase 492
- Phase 1/Phase 285
- Phase 2/Phase 314
Top conditions
- Glaucoma107
- Myopia88
- Cataract76
- Diabetic Retinopathy51
- Dry Eye38
- Keratoconus34
- Retinitis Pigmentosa33
- Age-Related Macular Degeneration31
- Amblyopia26
- Eye Diseases24
- Graves Disease24
- Sjogren's Syndrome24
- Dry Eye Disease (DED)23
- Multiple Sclerosis22
- Astigmatism21
- Ocular Hypertension21
- Diabetic Macular Edema20
- Macular Degeneration20
Leading sponsors
- Zhongshan Ophthalmic Center, Sun Yat-sen University25
- Medical University of Vienna20
- Second Affiliated Hospital, Zhejiang University, School of Medicine19
- Fondation Ophtalmologique Adolphe de Rothschild18
- Assistance Publique - Hôpitaux de Paris16
- National Taiwan University Hospital16
- The Hong Kong Polytechnic University16
- Eye & ENT Hospital of Fudan University15
- National Eye Institute (NEI)15
- Shanghai Eye Disease Prevention and Treatment Center15
Where studies are running
- California133
- Arizona68
- Florida43
- Maryland39
- Texas37
- New York36
- Massachusetts35
- Alabama26
- North Carolina20
- Pennsylvania20
Recruiting studies1,764 total
- NCT06638424Recruiting
Cataract surgery effects on eyes in diabetic patients
This study looks at how cataract surgery affects the surface of the eye in people with diabetes. Researchers want to see if the surgery causes changes, so they can better understand and care for diabetic patients.
StrasbourgAges 18 years+ - NCT07710196RecruitingPhase 3
NPI-001 for preserving vision in usher syndrome
This study tests a 24-month treatment with NPI-001, an oral medication, to see if it can slow the loss of light-sensing cells in the retina for people with retinitis pigmentosa tied to Usher syndrome. It aims to preserve remaining vision and delay further damage.
Dallas, TexasAges 18 years+ - NCT07712939RecruitingPhase 1
Study of CND319 for rheumatic diseases
This study tests a new drug called CND319 in healthy volunteers and people with rheumatoid arthritis or Sjögren's disease. The goal is to see if it is safe and how the body responds to it.
Melbourne, VictoriaAges 18–65 - NCT07708142RecruitingPhase 3
Testing a new injection for swelling after retinal vein blockage
This trial tests a new medicine called SMO1 for people with vision loss and swelling in the eye caused by a blocked vein in the retina. It involves regular eye injections to see if the medicine can reduce swelling and improve vision.
Seoul, Gangdong-guAges 19 years+ - NCT07713979Recruiting
VisionWay Accessibility study for people with vision loss
This study tests a new system called VisionWay to help people with severe vision loss or blindness navigate safely. Researchers want to see if it works better than a cane or guide dog alone.
Orono, MaineAges 18 years+ - NCT07711561RecruitingPhase 1
Cell therapy for cornea swelling after cataract surgery
This trial tests a simple cell treatment for a swollen cornea caused by cataract surgery. It aims to help your cornea become clear again without a full transplant.
Hyderabad, TelanganaAges 18–80 - NCT07707817Recruiting
Expanding preventive medicine access for mobile groups
This study tests whether giving preventive medicine to people who move or migrate can help control river blindness and lymphatic filariasis. It focuses on children and household heads who have missed past treatment rounds.
Ondo, Ondo, Taraba and Akwa IbomAges 5 years+ - NCT07713056Recruiting
Studying a glaucoma surgery for pigmentary glaucoma
This trial looks at how well a specific type of surgery (ab-interno 120° trabeculotomy) works for people with pigmentary glaucoma. It aims to understand the safety and effectiveness by tracking eye pressure and vision over time.
Wuhan, HubeiAges 16–80 - NCT07708740Recruiting
Two doses of ketamine for preventing slow heart rate during eye surgery
This study tests whether two doses of ketamine (a medicine given through a vein) can reduce a reflex that slows the heart during eye surgery. If you are having eye surgery that involves moving the eye muscles, you may be eligible.
CairoAges 18–65 - NCT06642870Recruiting
Self-management programme for rare rheumatic conditions
This trial is developing a self-management programme for people with rare rheumatic conditions like lupus, vasculitis, myositis, or Sjogren syndrome. It aims to help participants better manage their condition and improve their quality of life.
BristolAges 18 years+ - NCT04981145RecruitingPhase 4
Iguratimod for Sjögren’s syndrome symptoms and safety
This trial studies whether iguratimod improves symptoms in people with primary Sjögren’s syndrome, and checks how safe it is. It focuses on people with confirmed disease markers (anti-SSA/Ro-60) and ongoing dry eyes and dry mouth.
Hangzhou, ZhejiangAges 18–70 - NCT06643338Recruiting
Testing AI to spot eye nerve conditions in the ER
This trial is testing a new computer system that uses photographs of the back of your eye (color fundus photos) to help doctors quickly identify certain nerve or vision problems in the emergency room. If you come to the specific hospital and meet the basic requirements, this study will take pictures of your eyes to see if the AI can spot conditions more accurately.
ParisAges 18 years+ - NCT07705607RecruitingPhase 3
Comparing MK-8748 to standard treatment for diabetic eye swelling
This trial tests a new medicine (MK-8748) against an existing treatment (aflibercept) for people with diabetic macular edema, which causes vision loss due to swelling in the back of the eye. The goal is to see which works better to improve or protect vision.
Winter Haven, FloridaAges 18 years+ - NCT07705555RecruitingPhase 3
Comparing a new eye injection to standard treatment for diabetic eye swelling
This trial tests if a new medicine (MK-8748) works as well as or better than the usual treatment (aflibercept) for people with diabetic macular edema, a condition that causes vision loss from diabetes-related swelling in the back of the eye.
Glendale, CaliforniaAges 18 years+ - NCT06645626Recruiting
Health service use and quality of life in atypical Parkinson's
This study looks at how people with certain rare brain conditions (like progressive supranuclear palsy, corticobasal syndrome, or multiple system atrophy) use healthcare services and how their quality of life is affected. It may help doctors better support patients and their carers.
Southampton, HampshireAges 18 years+ - NCT07700498Recruiting
Combined cataract and glaucoma surgery for new patients
This trial tests a single surgery to treat both glaucoma and cataracts at the same time. It is for people who have not had any prior glaucoma treatment and need cataract surgery.
Ningxia, NingxiaAges 40–85 - NCT07705893Recruiting
Treating contact lens discomfort with a nasal spray
This trial tests a nasal spray (varenicline) to see if it can relieve discomfort and dryness from contact lens wear. If you wear daily disposable soft contacts and experience end-of-day eye dryness, you may be eligible.
Houston, TexasAges 18–99 - NCT07702149Recruiting
Diet for Behcet's disease patients with ringing in the ears
This trial tests whether a special diet can help ringing in the ears (tinnitus) in people with Behcet's disease who also have obesity. The goal is to see if dietary changes reduce tinnitus symptoms.
Giza, DokkiAges 40–55 - NCT07702123Recruiting
Physical activity study for women with Behcet's and metabolic syndrome
This study tests if a physical activity program helps women who have both Behcet's disease and metabolic syndrome. It aims to improve their health and well-being.
Giza, DokkiAges 40–50 - NCT07701759Recruiting
Oxygen levels during eye injections for premature babies
This study looks at how often low oxygen levels happen in premature babies when they get eye injections for a serious eye condition. The goal is to understand the risks and make the procedure safer.
BuraidahAges Any age - NCT07705061Recruiting
Measuring eye bulge in mexican adults
Researchers are measuring the normal distance that eyes stick out in Mexican adults. By taking these measurements, they hope to create better standards for detecting eye bulging in conditions like thyroid eye disease.
Mexico City, Mexico CityAges 18 years+ - NCT07698977Recruiting
Slowing nearsightedness with special glasses
This study tests special glasses to slow down nearsightedness (myopia) getting worse in children. Researchers want to see if these glasses help keep eyes from getting more nearsighted over time.
BudapestAges 6–15 - NCT05870566Recruiting
Vitamin and light treatment before risky corneal transplant
This trial studies whether pretreatment with a specific vitamin and ultraviolet light can help a future, high-risk corneal transplant keep its new cornea healthy for longer. It may help people whose corneas already have new blood vessels, which can make transplant results harder.
München, BavariaAges 18 years+ - NCT06650306Recruiting
Soft contact lenses and eye health in high myopia
This study looks at how wearing soft contact lenses affects the cornea and vision quality in people with high myopia before they have SMILE laser surgery. It may help doctors understand how to better prepare patients for the procedure.
Shanghai, Shanghai MunicipalityAges 18–45
Common questions
- How many eyes & vision clinical trials are recruiting?
- Clin2 is tracking 1,764 recruiting ophthalmology studies from the U.S. registry right now, out of 2,747 we cover in this area in total.
- What does “Eyes & vision” cover here?
- Eye disease and conditions that affect sight. We group each study into eyes & vision based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a eyes & vision trial near me?
- Use the search to filter eyes & vision studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Mental health
- Digestive system
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.