Ophthalmology
Eyes & vision clinical trials
Eye disease and conditions that affect sight. We’re tracking 1,819 recruiting studies in this area right now.
By phase
- Not applicable1,253
- Phase 3132
- Phase 2121
- Phase 1120
- Phase 492
- Phase 1/Phase 285
- Phase 2/Phase 316
Top conditions
- Glaucoma108
- Cataract89
- Myopia89
- Diabetic Retinopathy52
- Dry Eye42
- Keratoconus34
- Age-Related Macular Degeneration33
- Retinitis Pigmentosa31
- Sjogren's Syndrome29
- Diabetic Macular Edema26
- Eye Diseases26
- Graves Disease26
- Amblyopia24
- Astigmatism23
- Dry Eye Disease (DED)23
- Multiple Sclerosis23
- Retinal Disease23
- Ocular Hypertension22
Leading sponsors
- Zhongshan Ophthalmic Center, Sun Yat-sen University28
- Second Affiliated Hospital, School of Medicine, Zhejiang University23
- Medical University of Vienna19
- Fondation Ophtalmologique Adolphe de Rothschild18
- National Taiwan University Hospital17
- Assistance Publique - Hôpitaux de Paris16
- Eye & ENT Hospital of Fudan University15
- National Eye Institute (NEI)15
- Shanghai Eye Disease Prevention and Treatment Center15
- Duke University13
Where studies are running
- California141
- Arizona66
- Texas41
- Maryland39
- Massachusetts34
- New York34
- Florida32
- Alabama27
- North Carolina21
- Pennsylvania20
Recruiting studies1,819 total
- NCT07449936RecruitingPhase 3
Comparing a new long-lasting injection to standard one for DME
This phase 3 trial tests a new long-acting injection (EYP-1901) against a standard one (aflibercept) for people with diabetic macular edema. Both treatments are given as eye injections, and the goal is to see if the new drug works as well and may require fewer injections.
Bakersfield, CaliforniaAges 18 years+ - NCT07449923RecruitingPhase 3
Comparing a new injection to standard treatment for diabetic macular edema
This trial compares a new treatment (EYP-1901, given as an injection) to a standard injection (aflibercept) for people with diabetic macular edema. It aims to see which works better at reducing swelling and improving vision.
Gilbert, ArizonaAges 18 years+ - NCT06643403Recruiting
How aging affects oxygen use in the eyes of healthy people
This study looks at how the eyes use oxygen as people get older. It involves healthy volunteers between 18 and 80 years old who do not smoke, to see how their retinas process oxygen.
Vienna, State of ViennaAges 18–80 - NCT06893965Recruiting
Eye pressure check after Eylea 8mg injection
This trial measures eye pressure right after an injection of a higher-dose Eylea (aflibercept 8mg) to see how it affects the eye. It may help people who need frequent anti-VEGF shots for conditions like wet AMD or diabetic eye disease.
Toulon, VarAges 18 years+ - NCT05706896Recruiting
Cord blood plasma injections for dry macular degeneration
This trial tests whether injections made from umbilical cord blood “platelet-rich plasma” can improve vision in people with dry age-related macular degeneration (AMD) in both eyes. It targets older adults with specific vision levels and no major other eye or medical problems that could affect the results.
RomeAges 65 years+ - NCT06589128Recruiting
Eye product for digital eye strain in children
This study tests an eye product to see if it helps relieve digital eye strain (sore, tired, or dry eyes from screens) in children. It is for kids who have mild to moderate symptoms from using digital devices.
Kepala Batas, Pulau PinangAges 10–11 - NCT07424755Recruiting
AI eye test for cataract with high nearsightedness
This trial uses an artificial intelligence system to analyze detailed eye images from people who have both cataracts and severe nearsightedness (high myopia) with a specific eye shape (posterior staphyloma). The goal is to see if the AI can help doctors better understand and manage these conditions.
ShanghaiAges Any age - NCT06587113Recruiting
Study of attention and focus during visual search
This study explores how your brain focuses and ignores distractions while searching for things visually. It may help us understand attention processes in healthy adults.
Denver, ColoradoAges 18–65 - NCT06845163RecruitingPhase 2
Testing dapagliflozin for diabetic macular edema
This study tests whether a medication called dapagliflozin, which is usually used for diabetes and heart failure, can help reduce swelling in the retina (diabetic macular edema) and improve vision. It is for people with type 2 diabetes who are already taking insulin and metformin.
Alexandria, Alexandria GovernorateAges 18–85 - NCT05927428RecruitingPhase 2
Eye drops for neurotrophic corneal ulcers
This Phase 2 trial tests BRM424 eye drops in adults with neurotrophic keratitis (a weakened, slow-healing cornea) to see if they help and are safe over 28 days. You may be able to join if your condition matches Stage 2 or Stage 3 and you meet the safety rules.
Leland, North CarolinaAges 18 years+ - NCT06427629Recruiting
Eye cell imaging trial with moxifloxacin drops
This study uses a special camera to look at cells on the surface of your eye. It tests people using moxifloxacin eye drops either before eye surgery or for conditions like dry eye or Sjogren's syndrome.
SeoulAges 19–85 - NCT07376005Recruiting
How sugar affects eye thickness
This study looks at how a single sugary drink changes the thickness of a layer inside your eye (the choroid). It may help researchers understand how diet affects eye health.
Memphis, TennesseeAges 21–35 - NCT07364708Recruiting
Treating eye membrane detachment after cataract surgery
This trial tests a way to reattach the thin inner layer of the cornea (Descemet's membrane) that can detach after cataract surgery. It may help people who are diagnosed within the first week after surgery.
Minya, None SelectedAges 50 years+ - NCT07362927RecruitingEarly Phase 1
Gene therapy trial for diabetic macular edema
This study tests a new gene therapy called LX111 for diabetic macular edema (DME) that has not improved enough with previous injections. It aims to see if a single treatment can reduce swelling and improve vision.
ShanghaiAges 18 years+ - NCT04910503RecruitingPhase 4
Compare fluocinolone and dexamethasone implants for resistant eye swelling
This trial looks at which long-acting steroid implant works better for diabetic macular swelling that did not improve enough with past treatments. It may help patients by testing a treatment option aimed at improving vision when other eye injections have not worked well.
DijonAges 18 years+ - NCT06551766Recruiting
Light-activated gel for tear duct surgery
This trial tests a new light-activated gel to help keep the tear duct open after standard surgery. It may reduce the chance of the duct closing again.
ShanghaiAges 18–75 - NCT06487039RecruitingPhase 2
EB-203 for wet age-related macular degeneration
This trial tests a new medicine called EB-203 for people with wet age-related macular degeneration (AMD), a condition that causes blurry vision. It aims to see if the treatment is safe and can help improve or stabilize vision.
BusanAges 50 years+ - NCT03381794Recruiting
Cornea transplant registry for patients in Germany
This trial is not testing a new treatment. It collects and organizes information about people in Germany who have had a corneal (front-of-eye) transplant since 2001 to help future care and research.
Homburg, SaarlandAges 1–100 - NCT07582042Recruiting
Vision testing in geographic atrophy treated with pegcetacoplan
This study tests a specialized vision-testing method in people with geographic atrophy (a type of dry age-related macular degeneration) who are already receiving pegcetacoplan injections. The goal is to better understand how this treatment affects vision in different parts of the eye.
Salt Lake City, UtahAges 65–90 - NCT06491693Recruiting
Can eye nerve test predict brain complications after carotid surgery?
This trial checks if measuring the nerve sheath in your eye can help doctors predict brain-related problems after carotid artery surgery. It aims to improve safety during the procedure.
IstanbulAges 50–80 - NCT06536062Recruiting
Cord blood and platelet plasma for dry macular degeneration
This trial tests if a treatment made from umbilical cord blood and platelet-rich plasma can help people with dry age-related macular degeneration. The treatment is given as an injection into the eye, and the goal is to see if it slows vision loss or improves sight.
Rome, RomeAges 65 years+ - NCT06492863RecruitingPhase 1/Phase 2
Gene therapy (FT-003) for wet AMD
This trial tests a new gene therapy, FT-003, for people with wet AMD. It aims to see if a single treatment can help stop vision loss and may reduce the need for frequent eye injections.
Tianjin, Tianjin,ChinaAges 50–80 - NCT06492850RecruitingPhase 1/Phase 2
Gene therapy for RPGR-related retinitis pigmentosa
This trial tests a gene therapy for people with a specific genetic form of retinitis pigmentosa (caused by changes in the RPGR gene). It aims to improve vision and slow disease progression.
Beijing, Beijing MunicipalityAges 8–45 - NCT06924944Recruiting
A study of a new lens for people who had laser eye surgery
This study looks at how well a type of artificial lens (Clareon Vivity) works for people who have had laser eye surgery in the past and now need cataract surgery. It aims to see if this lens gives good vision without glasses.
Ogden, UtahAges Any age
Common questions
- How many eyes & vision clinical trials are recruiting?
- Clin2 is tracking 1,819 recruiting ophthalmology studies from the U.S. registry right now, out of 2,909 we cover in this area in total.
- What does “Eyes & vision” cover here?
- Eye disease and conditions that affect sight. We group each study into eyes & vision based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a eyes & vision trial near me?
- Use the search to filter eyes & vision studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Mental health
- Digestive system
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.