Ophthalmology
Eyes & vision clinical trials
Eye disease and conditions that affect sight. We’re tracking 1,819 recruiting studies in this area right now.
By phase
- Not applicable1,253
- Phase 3132
- Phase 2121
- Phase 1120
- Phase 492
- Phase 1/Phase 285
- Phase 2/Phase 316
Top conditions
- Glaucoma108
- Cataract89
- Myopia89
- Diabetic Retinopathy52
- Dry Eye42
- Keratoconus34
- Age-Related Macular Degeneration33
- Retinitis Pigmentosa31
- Sjogren's Syndrome29
- Diabetic Macular Edema26
- Eye Diseases26
- Graves Disease26
- Amblyopia24
- Astigmatism23
- Dry Eye Disease (DED)23
- Multiple Sclerosis23
- Retinal Disease23
- Ocular Hypertension22
Leading sponsors
- Zhongshan Ophthalmic Center, Sun Yat-sen University28
- Second Affiliated Hospital, School of Medicine, Zhejiang University23
- Medical University of Vienna19
- Fondation Ophtalmologique Adolphe de Rothschild18
- National Taiwan University Hospital17
- Assistance Publique - Hôpitaux de Paris16
- Eye & ENT Hospital of Fudan University15
- National Eye Institute (NEI)15
- Shanghai Eye Disease Prevention and Treatment Center15
- Duke University13
Where studies are running
- California141
- Arizona66
- Texas41
- Maryland39
- Massachusetts34
- New York34
- Florida32
- Alabama27
- North Carolina21
- Pennsylvania20
Recruiting studies1,819 total
- NCT06810011Recruiting
Eye disease treatment study using medical records
This study uses a computer system to look at medical records of people who have had a certain type of eye injection. It aims to improve how information about eye treatments is shared and understood.
Chemnitz, SaxonyAges 18 years+ - NCT07081945Recruiting
Human amniotic membrane for inferior retinal detachment
This study tests whether a special membrane (human amniotic membrane) can help repair a detached retina, especially if the tear is in the lower part of the eye. It might be a good option if standard surgery is harder to do because of scarring or a tear's location.
Shanghai, Shanghai MunicipalityAges 18–70 - NCT06824935Enrolling by invitation
Cataract surgery anesthesia needs study
This study looks at how much anesthesia is needed during outpatient cataract surgery. It may help find the right approach for your comfort and safety.
IstanbulAges 18 years+ - NCT07663331RecruitingPhase 4
Adalimumab for adults with non-infectious uveitis
This study tests an injection called adalimumab (Tebiovio®) to see if it helps control inflammation in the eyes of adults with non-infectious uveitis. It might be a good option if you are already on steroid pills and looking for another treatment.
Tianjin, Tianjin MunicipalityAges 18 years+ - NCT07050095Recruiting
Virtual reality vs. medication for anxiety before eye surgery
This trial compares using a virtual reality headset against a standard anti-anxiety medication (midazolam) to help patients relax before dacryocystorhinostomy (tear duct) surgery. It aims to find a non-drug way to reduce anxiety.
CairoAges 18–65 - NCT07305987RecruitingPhase 3
Eye drop study for people after cataract surgery
This study tests a new anti-inflammatory eye drop (PRO-232) in people who had routine cataract surgery on one eye the day before. The goal is to see if it helps control swelling and pain without problems.
Tijuana, Estado de Baja CaliforniaAges 18 years+ - NCT06749639RecruitingEarly Phase 1
Gene therapy trial for RDH12-related eye disease
This trial tests an injection called PUMCH-E101 for people with vision loss caused by changes in the RDH12 gene. The goal is to see if it is safe and if it can help improve vision.
Beijing, Beijing MunicipalityAges 8–45 - NCT07285070RecruitingPhase 2
Tacrolimus eye drops for non-infectious anterior uveitis
This trial tests a new eye drop (tacrolimus) to treat non-infectious anterior uveitis, an inflammation in the front part of the eye. It may help reduce the need for steroid eye drops.
Phoenix, ArizonaAges 18 years+ - NCT06997354Recruiting
Parent survey to screen children for vision brain problems
This trial is testing a questionnaire for parents to help spot signs of vision problems in children that come from how the brain processes sight, not from the eyes themselves. It aims to make early detection easier for families and doctors.
Louvain-la-NeuveAges 3 years+ - NCT07537166Enrolling by invitation
Atropine Drops and Ear Acupressure for Childhood Myopia
This trial tests whether very low-dose atropine eye drops combined with acupressure on the ear can slow down myopia (nearsightedness) progression in children. Researchers will also check how the treatment affects the inner eye tissue.
Taichung, North StrictAges 6–12 - NCT05210803Enrolling by invitationPhase 2
Long-term safety follow-up for wet AMD treatment
This study is a follow-up for people who have already received an injection of RGX-314 for wet age-related macular degeneration (AMD) in an earlier trial. It looks at how the treatment works over a longer time and any long-term effects.
Phoenix, ArizonaAges Any age - NCT03714503Recruiting
Head positioning after retinal detachment surgery
This study looks at whether a specific head position after retinal detachment repair affects healing. It may help patients learn a safer, more effective way to position their head while recovering.
Prairie Village, KansasAges 18 years+ - NCT07236671Recruiting
Study of enlarged eye blood vessel changes
This study looks at how certain enlarged blood vessels in the back of the eye change over time. By taking special images, researchers hope to learn more about these vessels. It might help if you have been told you have pachyvessels.
Hong KongAges 45 years+ - NCT06985706RecruitingPhase 3
Comparing two treatments for diabetic eye swelling after initial injections
This trial tests whether switching from anti-VEGF injections to a special laser is better than continuing injections alone for people with diabetic macular edema whose central retinal thickness has dropped below 400 microns after the first year of treatment.
BelfastAges 18 years+ - NCT05802329RecruitingPhase 1
Testing eye injections for diabetic macular swelling
This Phase 1 study tests the safety and early effectiveness of OCU200 eye injections in people with diabetic macular edema (DME) that affects the center of vision. It may help by reducing the eye swelling that blurs vision from diabetes.
Deerfield Beach, FloridaAges 18 years+ - NCT06952452RecruitingPhase 3
Testing genes to improve AMD treatment
This trial studies how genes affect response to anti-VEGF injections for a common form of age-related vision loss (wet AMD). It aims to tailor treatment to each patient.
San Cristóbal de La Laguna, Santa Cruz De TenerifeAges 50 years+ - NCT07185841RecruitingPhase 1/Phase 2
Oral tablets for wet macular degeneration
This trial tests an experimental oral tablet for people with wet age-related macular degeneration. It may offer a new way to treat the condition without frequent eye injections.
BeijingAges 50–85 - NCT06849375Recruiting
Eye cell check after lens implant for nearsightedness
This trial checks how a special lens implant (called a phakic IOL) affects the cells on the inside of your cornea (the clear front part of your eye). It is for people with high nearsightedness who want better vision without glasses or contacts.
Sohag, Sohag GovernorateAges 18–35 - NCT05874310RecruitingEarly Phase 1
Gene therapy trial for RPGR-related vision loss
This early study tests a gene therapy designed for people whose vision problems are caused by an RPGR genetic change. It may help slow or improve the eye disease by treating the underlying cause.
Beijing, Beijing MunicipalityAges 8–45 - NCT06839443Recruiting
AI to detect hydroxychloroquine eye damage
This study uses artificial intelligence to look at eye images of people who have taken hydroxychloroquine for a long time. The goal is to better detect or predict early signs of retinal damage, so you can get the right care sooner.
PortugalAges 18–100 - NCT06830538Recruiting
Recovery and quality of life after corneal transplant
This study looks at how well people recover after a corneal transplant, including their vision, eye health, and overall quality of life. It aims to learn what helps people heal best after surgery.
BolognaAges 18 years+ - NCT06818747Recruiting
Comparing two cornea transplant methods for advanced bullous keratopathy
This trial compares two types of cornea transplant surgery (PKP and DSAEK) to see which one helps people with severe corneal swelling see better after two years. It may be an option if you have advanced bullous keratopathy and need a first-time cornea transplant.
BesançonAges 50 years+ - NCT06834906Recruiting
Usability test of the Easy-EyeFM AI platform
This study tests how easy it is to use the Easy-EyeFM AI platform, a new tool that may help with eye exams. If you are a medical student or doctor, you can help by using the platform for about an hour and sharing your experience.
BeijingAges 18–80 - NCT05555589RecruitingPhase 3
RGN-259 eye drops for neurotrophic keratopathy with persistent corneal defects
This Phase 3 trial tests whether a 0.1% RGN-259 eye drop can safely improve a stubborn corneal wound in adults with neurotrophic keratopathy (nerve-related corneal healing problems). You may qualify if you still have an eye surface defect after at least a week of standard treatments, and you meet specific measurements for corneal sensitivity and vision.
Laguna Hills, CaliforniaAges 18 years+
Common questions
- How many eyes & vision clinical trials are recruiting?
- Clin2 is tracking 1,819 recruiting ophthalmology studies from the U.S. registry right now, out of 2,909 we cover in this area in total.
- What does “Eyes & vision” cover here?
- Eye disease and conditions that affect sight. We group each study into eyes & vision based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a eyes & vision trial near me?
- Use the search to filter eyes & vision studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
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- Pain
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Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.